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Amytrx Therapeutics Announces Open Enrollment for Phase 2b Clinical Trial of AMTX-100 CF3, a Promising Anti-Inflammatory Peptide Therapeutic for Atopic Dermatitis

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NASHVILLE, June 28, 2023 /PRNewswire/ — Amytrx Therapeutics, an emerging pharmaceutical company specializing in innovative anti-inflammatory therapies, is pleased to announce the open enrollment for its highly anticipated Phase 2b clinical trial of a topical formulation of AMTX-100 CF3, a groundbreaking anti-inflammatory peptide therapeutic designed to treat patients suffering from mild to moderate atopic dermatitis. This milestone marks a significant step forward in the development of advanced treatment options for individuals affected by this chronic and debilitating skin condition.

The trial’s primary endpoints include improvement in disease severity, reduction in symptoms, and assessment of safety.

Atopic dermatitis, also known as eczema, affects millions of adults worldwide, causing intense itching, redness, and dry skin (1). Despite the availability of various treatment options, there remains an unmet need for more effective and safer therapies. With this topical formulation of AMTX-100 CF3, Amytrx Therapeutics aims to revolutionize the treatment landscape and offer hope to those living with atopic dermatitis.

The Phase 2b clinical trial will continue to build upon a recent trial that has evaluated the safety and efficacy of AMTX-100 CF3 in a larger cohort of adult patients that has shown favorable efficacy bypassing the need for rescue steroid treatment. This randomized, double-blind, placebo-controlled study will be conducted at 8-10 clinical sites across the country. This study is seeking 60 participants to generate a 1:1 ratio between placebo and active arms of the study. The trial’s primary endpoints include improvement in disease severity, reduction in symptoms, and assessment of treatment safety.

This clinical trial will include a 28-day treatment period with twice daily treatment and a 2-week follow-up assessment post-treatment to determine therapeutic efficacy. In addition, participants will receive a topical emollient 2-weeks prior to trial to exclude participants who may be impacted by a placebo effect. Precision medicine techniques will also be used to assess changes in the expression of genes involved in inflammation.

“We are thrilled to initiate the open enrollment for our Phase 2b clinical trial of AMTX-100 CF3,” said Dr. Matthew A. Gonda, CEO of Amytrx Therapeutics. “At Amytrx, we are committed to developing innovative therapies that can make a meaningful difference in the lives of patients. This trial represents a crucial step towards bringing a safe and targeted treatment option to adults suffering from atopic dermatitis, in addition to other chronic inflammatory skin diseases such as psoriasis, vitiligo, lupus, graft vs. host, and more.”

Amytrx Therapeutics has invested years of research and development into the creation of AMTX-100 CF3. This unique topical formulation of their anti-inflammatory peptide has shown promising results in preclinical and clinical studies. AMTX-100 CF3 utilizes a novel untapped intracellular target to control inflammation. The company believes that AMTX-100 CF3 has the potential to provide durable relief, enhance quality of life, and minimize the burden of this chronic condition with a revolutionary approach that interacts with a key checkpoint in the initiation of inflammation.

The open enrollment for the Phase 2b clinical trial of AMTX-100 CF3 is now underway. Eligible adults interested in participating or learning more about the trial are encouraged to visit the ClinicalTrials.Gov listing # NCT04313400 or visit Amytrx Therapeutics’ website at www.amytrx.com. The company welcomes collaboration with research institutions that wish to contribute to advancing the knowledge and treatment of other inflammatory skin disorders.

The current topical formulation of AMTX-100 CF3 being studied in the Phase 2b clinical trial provides an example of the various formulations available for novel anti-inflammatory peptide AMTX-100. Amytrx Therapeutics is actively exploring other delivery methods to cater to the diverse needs of patients across a variety of inflammatory diseases. These formulations include oral, injectable, nasal spray, and other options. This comprehensive approach underscores Amytrx Therapeutics’ commitment to developing a range of therapeutic options that can effectively target inflammation and provide additional treatment strategies.

About Amytrx Therapeutics

Amytrx Therapeutics, Inc. is a clinical-stage biopharmaceutical company pioneering the first anti-inflammatory human peptide platform (AMTX-100) yielding the potential for vastly optimized, cutting-edge therapies that safely alter the course of chronic inflammation and metabolic dysfunction to prevent and treat some of the world’s most debilitating diseases. For further information, please visit www.amytrx.com

Kapur, S., Watson, W., & Carr, S. (2018). Atopic dermatitis. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 14(Suppl 2), 52. https://doi.org/10.1186/s13223-018-0281-6

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SOURCE Amytrx Therapeutics

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UNISORB Welcomes BILZ-USA to Expand Engineering and Product Solutions

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UNISORB Named Sole North American Distributor for BILZ

MICHIGAN CENTER, Mich., Sept. 2, 2026 /PRNewswire/ — UNISORB Installation Solutions, a global provider of machine mounting, vibration isolation, and precision leveling solutions headquartered in Michigan Center, Mich., today announced it has acquired BILZ-USA, effective August 30, 2026, making UNISORB the exclusive distributor of BILZ products across North America. The transition expands UNISORB’s engineering support and on-site project management capabilities for industrial customers seeking precision vibration isolation and leveling solutions. Full product and service details are available at www.UNISORB.com.

UNISORB is now the exclusive North American distributor of BILZ products.

“BILZ’s leveling and isolation technology closes a gap in our product line at the high-precision end of the market,” said John Hornberger, Chief Executive Officer of UNISORB. “Combining our installation and project management teams with BILZ’s engineering staff means customers get one point of contact for a project that used to require two vendors.”

What This Means for Customers

Decades of combined expertise. BILZ’s engineering staff join UNISORB’s engineering and project management teams, giving customers a single technical team backed by decades of hands-on experience in vibration isolation, leveling, and precision installation.A broader, unified product line. UNISORB’s lineup now spans BILZ’s full catalog, from basic leveling mounts to active isolation systems, alongside UNISORB’s existing machine mounting and installation solutions, giving customers access to a significantly wider range of solutions from a single source.More capability for BILZ customers. Longtime BILZ customers now gain direct access to UNISORB’s full engineering, manufacturing, and on-site project management resources; capabilities not previously available through BILZ alone.A unified approach to installation. Customers receive continuous support from initial site survey through final leveling and installation, managed by one team rather than coordinated separately across two vendors.Centralized North American distribution. Distribution from Michigan Center will consolidate logistics for customers ordering across North America as the transition is completed.One point of contact. BILZ orders will transition to being placed directly through UNISORB in the coming weeks, moving away from what was previously a two-vendor process for combined leveling and isolation projects.

About UNISORB

UNISORB Installation Solutions, headquartered in Michigan Center, Michigan, is a global provider of machine mounting, vibration isolation, and precision equipment leveling solutions for manufacturers across a range of industrial sectors. More information is available at www.UNISORB.com.

Media Contact

John Hornberger

Chief Executive Officer, UNISORB

jhornberger@unisorb.com

Tim Spahr 
Vice President – Sales & Marketing
tspahr@unisorb.com

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SOURCE UNISORB Installation Solutions

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Eliminate costly enclosures: ABB debuts IP66/Type 4X Drives for Australia’s harshest industrial environments

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New ACS580, ACH580 and ACQ580 IP66/Type 4X drives support food and beverage, HVACR, manufacturing, and water and wastewater applications exposed to harsh environmental conditions.

MELBOURNE, Australia, Sept. 3, 2026 /PRNewswire/ — ABB has introduced ACS580, ACH580 and ACQ580 drives with IP66/Type 4X protection, extending the range of motor control solutions available for applications operating in demanding environmental conditions. The new drives are designed for installations where motor control equipment may be exposed to dust, water, humidity, outdoor weather and other harsh conditions, providing greater flexibility when considering drive selection, installation design and equipment location.

Tailored for different industry requirements

The three drive families are designed to address the specific requirements of different industries and applications:

ACS580 IP66/Type 4X drives are designed for demanding food and beverage environments, supporting motor-driven applications including pumps, fans, compressors, mixers and conveyors operating across wet, washdown, indoor and outdoor production environments.ACH580 IP66/Type 4X drives are designed specifically for HVACR applications, supporting equipment operating in exposed and outdoor locations, including rooftop air handling units, cooling towers, exterior exhaust fans, outdoor pump skids and outdoor chiller units.ACQ580 IP66/Type 4X drives are designed for water and wastewater environments, supporting a broad range of applications including clarifiers, surface aerators, screens, flocculators, dosing systems, activated sludge pumps, lift stations and booster stations.

Many Australian facilities operate in environments that present challenging conditions for installed electrical equipment. The IP66/Type 4X design provides greater flexibility to locate drives closer to the application, where appropriate for the installation.

By reducing the need for additional protective enclosures or dedicated electrical rooms and enabling shorter motor cable runs, this approach can reduce site installation costs and complexity. It can also support faster installation and commissioning and a smaller overall system footprint.

The drives incorporate a range of built-in features designed to support installation, operation and integration, including coated circuit boards, integrated EMC C2 filtering, a built-in DC choke for harmonic mitigation, and Safe Torque Off (STO). The design also provides option slots for additional I/O and fieldbus communications, enabling the drives to be configured for different application requirements.

Optional Bluetooth-enabled control panels further support commissioning and interaction with the drives. When used with ABB’s Drivetune mobile application, Bluetooth connectivity provides a convenient way to access and work with drive settings. ABB’s drive software and connectivity tools can also support commissioning and diagnostic activities.

ABB is also highlighting the importance of distinguishing ingress protection ratings from other environmental performance characteristics when selecting equipment for demanding applications.

In Australia, an IP66 rating relates specifically to the enclosure’s protection against the ingress of dust and water, in accordance with AS/NZS 60529 and IEC 60529. The first digit, 6, denotes a dust-tight enclosure, while the second 6 denotes protection against powerful water jets.

Environmental characteristics such as UV, corrosion and chemical resistance should therefore be considered separately from the IP66 classification and assessed against the specifications and testing applicable to the individual product. This distinction is particularly relevant for equipment installed in outdoor, coastal, washdown or chemically exposed environments. ABB, for example, separately identifies corrosion, UV and chemical-resistance characteristics for its ACS580 IP66/Type 4X drive rather than treating these as properties conferred by the IP66 rating itself.

The ACS580, ACH580 and ACQ580 IP66/Type 4X drive range is available in power ratings from 5.5 kW to 22 kW, providing a solution for applications where protection against dust ingress and water exposure is an important consideration in the selection, installation and operation of variable speed drives.

Learn more: https://www.youtube.com/watch?v=9nCWb7g-MGI

About ABB
ABB (ABBN: SIX Swiss Ex) is a leading global technology company that energizes the transformation of society and industry to achieve a more productive, sustainable future. By connecting software to its electrification, robotics, automation and motion portfolio, ABB pushes the boundaries of technology to drive performance to new levels. With a history of excellence stretching back more than 130 years, ABB’s success is driven by about 110,000 talented employees in over 100 countries.

ABB Drives is a global technology leader serving industries, infrastructure and machine builders with world-class variable speed drives, drive systems and packages. We help our customers, partners and equipment manufacturers to improve energy efficiency, asset reliability, productivity, safety and performance.

Media Contact:
Natalie Landrito
Marketing and Communications Manager
contact.centre@au.abb.com

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SOURCE ABB

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7 Wolves Consulting Announces Release of Founder Danielle D. Pollard’s Debut Book, Act Like a Lady, Speak Like a Wolf

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7 Wolves Consulting founder and creator of the W.O.L.F. framework brings nearly three decades of engineering-backed insight to a new book on executive communication for professional women in male-dominated industries.

OAK PARK, Ill., Sept. 2, 2026 /PRNewswire/ — Danielle D. Pollard, Managing Partner of 7 Wolves Consulting and a corporate communication strategist with nearly 30 years of experience, announced the release of her debut book, Act Like a Lady, Speak Like a Wolf: From Surviving the Room to Owning It, now available on Amazon.

The book distills the philosophy Pollard has built across a career spanning industrial engineering, Agile software delivery, and Scrum coaching: that communication is not a soft skill, but a measurable performance system. Drawing on her engineering background and years spent inside complex corporate teams, Pollard argues that the biggest barrier to high performance is rarely strategy or talent; it is language. “Problems don’t live in circumstances,” she has said of her approach. “They live in language.”

That philosophy has already been proven in the field. At Allstate, Pollard was brought in to diagnose why a 60-person team spread across four offices and three time zones had not shipped a working feature in nine months. Rather than prescribing a fix, she used targeted questioning to surface the communication breakdowns the team could not see on its own. The result: a working demo in three weeks, roughly $3 million in recovered productivity, and a project completed three months ahead of schedule.

Act Like a Lady, Speak Like a Wolf takes that same engineering lens and applies it to a challenge Pollard has lived personally: navigating high-stakes, male-dominated corporate rooms as a Black woman in leadership. The book introduces her signature W.O.L.F. framework, a method for helping professional women watch their language, take ownership of outcomes, construct more constructive conversations, and measure the results, turning executive presence into a repeatable skill rather than an innate trait.

The book moves between personal narrative and professional framework, with chapters such as “The Kitchen Table” and “The Unsaid” tracing the moments that shaped Pollard’s thinking long before she named it the W.O.L.F. method.

“For almost 30 years, I watched brilliant leaders lose rooms, deals, and opportunities, not because they lacked the answers, but because they didn’t have the language to own the moment,” said Pollard. “This book is the guide I wish someone had handed me decades ago. It’s for every woman who has ever had to be the only one like her in the room and still found a way to win.”

Act Like a Lady, Speak Like a Wolf: From Surviving the Room to Owning It is available now on Amazon at a.co/d/02GJbajH. For more information about Danielle D. Pollard and 7 Wolves Consulting, visit www.DanielleDPollard.com.

Pollard will follow the release with a national speaking and book tour, bringing the W.O.L.F. framework directly to corporate teams, conferences, and live audiences. Tour details are being announced on a rolling basis at danielledpollard.com/booktour.

About Danielle D. Pollard & 7 Wolves Consulting

Danielle D. Pollard is the Managing Partner of 7 Wolves Consulting and a communication strategist known as “The Engineer of Executive Communication.” With nearly three decades in industrial engineering, Agile delivery, and Scrum coaching, she has helped teams inside organizations such as Allstate, UPS, Apartments.com, and Blue Cross Blue Shield move from stagnation to measurable performance. Through her W.O.L.F. framework, keynote speaking, and executive coaching, she helps professional women, particularly those in male-dominated industries, move from surviving the room to owning it.

Media Contact
Name: Danielle D. Pollard
Website: https://www.danielledpollard.com/
Email: danielle@7wolvesconsulting.com

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