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Esperto Medical Announces Study Results Measuring Blood Pressure with Sound

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New technology called Resonance Sonomanometry™ uses acoustic stimulation for noninvasive continuous blood pressure monitoring with accuracy within 2%—and no calibration required.

IRVINE, Calif., July 31, 2024 /PRNewswire/ — Esperto Medical™, Inc. a healthtech startup specializing in critical care and remote patient monitoring, has published study results in PNAS Nexus evaluating their Resonance Sonomanometry™ (RSM) technology, a new calibration-free, continuous, noninvasive blood pressure technology. The study compared Esperto’s technology to reference measurements both in-vitro and in-vivo, demonstrating accuracy within 2 mmHg (~2%).

The wearable technology is calibration-free, accurate for all patients, and can be used on multiple parts of the body

“RSM is an absolute measurement of blood pressure,” said Esperto Chief Technology Officer Raymond Jimenez. “Studies show that current noninvasive tools, which measure relative blood pressure can lack accuracy and be hard to use in many cases. These devices also require time-consuming calibration—an issue in situations when every minute counts. RSM is an important advancement over existing tools; it’s calibration-free, accurate for all patients, and can be used on multiple parts of the body.”

Originally developed at the California Institute of Technology, RSM uses sound waves at different frequencies to detect resonance in blood vessels. Taking thousands of measurements per second, it shows blood pressure variations throughout the cardiac cycle, allowing clinicians to find and correct blood pressure anomalies quickly and efficiently. Since RSM only uses sound waves, it can be placed on the arms, legs, and even the neck. It also requires no calibration, making it easy to set up and use.

“Accurate blood pressure measurement is essential for high quality medicine, but the gold standard invasive arterial catheter has many risks, so can only be used in the critically ill. RSM can provide continuous blood pressure (and other metrics) to all patients in a safe and easy to use arm or wrist band,” said Esperto cofounder and Chief Medical Officer, Alaina Rajagopal, MD PhD. “Cardiovascular disease is the leading cause of death worldwide. Accurate, continuous, noninvasive, calibration-free blood pressure, like what we’re developing at Esperto, has the potential to improve medical care for all patients.”  

To read the full study, “Resonance sonomanometry for noninvasive, continuous monitoring of blood pressure”, visit PNAS Nexus.

About Esperto Medical™
Esperto is dedicated to delivering the future of healthcare and expanding access by creating revolutionary noninvasive diagnostic technologies. Medicine is ready for huge breakthroughs, yet the burden of some essential tasks, like vital sign monitoring, hinders efficiency. Esperto aims to free clinicians and patients from the limitations of outdated technology. Learn more at www.esperto.health.

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SOURCE Esperto Medical

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ZNShine Solar Powers Honduras’ Renewable Future with 50MW Patuca Solar Project

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TERRERO BLANCO, Honduras, March 26, 2025 /PRNewswire/ — ZNShine Solar, a global leader in photovoltaic technology, today announced its role as module supplier for the 50MW Patuca Solar Project in Honduras. The project, developed by Empresa Nacional de Energía Eléctrica de Honduras (ENEE) and used Representaciones Mecánico Eléctricas, S.A. (REMESA) as EPC, represents a significant step in the country’s clean energy transition.

Financed through non-recourse debt by the Central Bank Honduras in December 2024, the project utilizes ZNShine’s high-efficiency 12BB PERC Monofacial Double-Glass Modules, selected for their:

Superior durability in harsh weather conditionsEnhanced energy yield for optimal performanceProven wind resistance, ideal for large-scale installations

Scheduled for commissioning in October 2025, the installation will significantly expand Honduras’ renewable energy capacity while supporting national energy security goals.

“Projects like Patuca demonstrate how advanced solar technology can drive sustainable development,” said William Wang, CEO at ZNShine Solar. “Our modules deliver the reliability and efficiency needed for Honduras’ energy future.”

About ZNShine Solar
A BNEF Tier 1 manufacturer and PVEL Top Performer, ZNShine Solar (founded 2006) delivers high-performance PV modules and integrated solutions across 60+ countries. With 10GW+ global capacity and manufacturing bases in China and internationally, the company is recognized for technological innovation in the Global Top 500 New Energy Enterprises.

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SOURCE ZNSHINE

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Patent Index 2024: US Innovation Remains Strong Despite Global Economic Uncertainties

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U.S. ranks first in European patent applications, followed by Germany, Japan, China, and Republic of Korea European Patent Office (EPO) received nearly 200,000 patent applications last year, with U.S. companies and inventors contributing nearly a quarter of thoseKey sectors for the U.S.: Medical technology, computer technology and digital

MUNICH and NEW YORK, March 25, 2025 /PRNewswire/ — Companies and inventors from around the world filed 199,264 patent applications at the European Patent Office (EPO) last year, according to the Patent Index 2024 published today. The U.S. maintained its position as the top country of origin for European patent applications, followed by Germany, Japan, China, and the Republic of Korea. U.S. innovators filed 47,787 applications, accounting for 24% of the total at the EPO in 2024.

Overall, the high level of patenting activity at the EPO was on a par with the previous year (2023: 199 452, -0.1%), following three years of significant growth. Patent applications from Europe, including all 39 EPO member states, rose by 0.3%, while those from outside Europe fell slightly (-0.4%). Notably, R. Korea saw the strongest growth (+4.2%), China’s growth slowed to +0.5%, while companies and inventors from the U.S. (-0.8%) and Japan (-2.4%) filed fewer applications.    

“Despite global uncertainties, U.S. companies and inventors continue to invest in research and development,” said EPO President António Campinos. “The rapid rise of digital technologies and AI is spurring innovation across all sectors. In 2024, the U.S. was one of the main drivers in advancing computer technology to the top technology field at the EPO. This underscores Europe’s significance as a key technology market for U.S. companies, offering a high-quality patent system that supports the development of strong IP portfolios.”

U.S. Top Fields of Technology: Surge in Computers, led by AI
The leading fields of technology for U.S. applicants at the EPO reflect significant strengths in various high-growth industries. The top three in 2024 were:

Medical technology: top field with 5,995 applications, reflecting continued investment in healthcare innovation, although it experienced a slight decrease of 2.9% compared to 2023.Computer technology: with 5,776 applications, this field saw a significant increase of +11.4% from the U.S. Growth from the U.S. was even higher (+20%) in AI-related fields such as machine learning and pattern recognition.Digital communication: which includes inventions related to mobile networks, accounted for 4,628 applications, but experienced a decrease of 4.8%.

U.S. Tech Companies Lead Innovation Push
Out of all global applicants, six of the top 20 businesses with most applications at the EPO are U.S.-based. They include: semiconductor manufacturer Qualcomm (with 3,015 patent applications, ranking 4th globally), aerospace and defence company RTX (2,061 applications), Alphabet (1,171), Microsoft (1,131), InterDigital (863), and Apple (806).

Samsung back at No. 1 in EPO Applicant Ranking
Samsung was the leading filer of patent applications at the EPO overall in 2024 (having last topped the ranking in 2020), Huawei dropped to second, followed by LG, Qualcomm and RTX.

Further information

View the Patent Index 2024 in full

 

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SOURCE European Patent Office (EPO)

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Canaan Inc. Expands Self-Mining Footprint in North America

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New mining partnerships to add ~4.7 EH/s

Mining machines to be hosted at facilities in Pennsylvania and Texas

Self-mining energization expected in coming months

SINGAPORE, March 26, 2025 /PRNewswire/ — Canaan Inc. (NASDAQ: CAN) (“Canaan” or the “Company”), an innovator in crypto mining, today announced that wholly owned subsidiaries of Canaan have signed agreements that expand the Company’s self-mining capabilities at two new partners’ mining facilities in Pennsylvania and Texas.

A three-year master colocation agreement has been entered into with Mawson Hosting LLC, an affiliate of Mawson Infrastructure Group Inc. (NASDAQ: MIGI), for its facility in Midland, Pennsylvania. This expansion in Pennsylvania, together with another recently executed 24-month equipment hosting agreement for a facility in Edna, Texas, is expected to add around 4.7EH/s of North American hashrate to Canaan’s self-mining computing power. The majority of this hashrate is expected to be installed by the second quarter of 2025.

“Our team has been evaluating mining sites across North America for several months, patiently looking for self-mining and partnership opportunities that made sense for our business.  We believe that these two new partners have goals that align with Canaan’s and that we can build long-term relationships with them,” said Nangeng Zhang, chairman and chief executive officer of Canaan.  “The U.S. has regulatory policies that support our Company’s ambitions, and we believe that we will be able to find additional partnerships and sites that will help us to increase our presence in the U.S. through self-mining activities and provide us with additional opportunities for mining machine sales.”

“We are delighted to announce the partnership between Canaan and Mawson. This agreement aligns with our strategy of optimizing digital infrastructure and compute management capabilities with the latest-generation machines. By combining Canaan’s cutting-edge hardware and Mawson’s digital infrastructure innovation, we expect to create long-term value that will benefit both companies as well as the overall ecosystem,” said Rahul Mewawalla, chief executive officer and president of Mawson Infrastructure Group Inc.

About Canaan Inc.

Established in 2013, Canaan Inc. (NASDAQ: CAN), is a technology company focusing on ASIC high-performance computing chip design, chip research and development, computing equipment production, and software services. Canaan has extensive experience in chip design and streamlined production in the ASIC field. In 2013, Canaan’s founding team shipped to its customers the world’s first batch of mining machines incorporating ASIC technology in bitcoin‘s history under the brand name Avalon. In 2019, Canaan completed its initial public offering on the Nasdaq Global Market. To learn more about Canaan, please visit https://www.canaan.io/.

Safe Harbor Statement

This press release contains forward-looking statements. These statements are made under the “safe harbor” provisions of the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as “will,” “expects,” “anticipates,” “future,” “intends,” “plans,” “believes,” “estimates” and similar statements. Among other things, Canaan Inc.’s anticipated financing plans and its intended use of proceeds contain forward-looking statements. Canaan Inc. may also make written or oral forward-looking statements in its periodic reports to the U.S. Securities and Exchange Commission (“SEC”) on Forms 20-F and 6-K, in its annual report to shareholders, in press releases and other written materials and in oral statements made by its officers, directors or employees to third parties. Statements that are not historical facts, including statements about Canaan Inc.’s beliefs and expectations, are forward-looking statements. Forward-looking statements involve inherent risks and uncertainties. A number of factors could cause actual results to differ materially from those contained in any forward-looking statement, including but not limited to the following: the Company’s goals and strategies; the Company’s future business development, financial condition and results of operations; the expected growth of the bitcoin industry and the price of bitcoin; the Company’s expectations regarding demand for and market acceptance of its products, especially its bitcoin mining machines; the Company’s expectations regarding maintaining and strengthening its relationships with production partners and customers; the Company’s investment plans and strategies, fluctuations in the Company’s quarterly operating results; competition in its industry; and relevant government policies and regulations relating to the Company and cryptocurrency. Further information regarding these and other risks is included in the Company’s filings with the SEC. All information provided in this press release and in the attachments is as of the date of this press release, and Canaan Inc. does not undertake any obligation to update any forward-looking statement, except as required under applicable law.

Investor Relations Contact

Canaan Inc.
Xi Zhang
Email: IR@canaan-creative.com 

ICR, LLC.
Robin Yang
Tel: +1 (347) 396-3281
Email: canaan.ir@icrinc.com 

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SOURCE Canaan Inc.

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