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SOPHiA GENETICS Presents Ground-Breaking Multimodal Research on AI-Driven Patient Stratification at ESMO 2024

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Research highlights the use of multimodal machine learning to identify non-small cell lung cancer patients predicted to derive the most benefit from combination immunotherapy

BOSTON and ROLLE, Switzerland, Sept. 14, 2024 /PRNewswire/ — SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native healthcare technology company and a leader in data-driven medicine, will unveil new research at the European Society for Medical Oncology (ESMO) 2024. The study, conducted in collaboration with AstraZeneca, leverages advanced AI-driven techniques to identify subgroups of stage IV non-small cell lung cancer (NSCLC) patients who could most benefit from the addition of tremelimumab to durvalumab and chemotherapy.

The research is a retrospective, multimodal analysis of the POSEIDON Phase 3 clinical trial (NCT03164616). This trial originally demonstrated that the combination of tremelimumab, durvalumab, and chemotherapy significantly increases progression-free survival (PFS) and overall survival (OS) versus chemotherapy in patients with metastatic NSCLC, which lead to approval of this regiment globally in 1L mNSCLC. The SOPHiA GENETICS study used cutting-edge multimodal machine learning models to analyze clinical, biological, genomic, and imaging data, pinpointing patient subgroups who are most likely to benefit from the combination treatment.

The research highlighted signatures identifying patients with non-squamous metastatic NSCLC who may derive higher OS benefit from the addition of tremelimumab to durvalumab plus chemotherapy in the first-line treatment setting. In particular, EGFR wild-type, FGFR3 wild-type, CDKN2A wild-type, KRAS mutation, and STK11 mutation comprised elements of a signature was identified as being associated with a higher OS benefit. These findings could have significant implications for the treatment of NSCLC, as it provides an exploration avenue towards a more tailored approach to patient care.

“Our collaboration with AstraZeneca represents a major step forward in personalized oncology. Non-small cell lung cancer remains one of the most challenging cancers to treat due to its complex biology and the late stage at which it is often diagnosed,” said Jurgi Camblong, Ph.D., Co-founder and CEO of SOPHiA GENETICS. “This study harnesses the power of multimodal data and advanced AI to identify which patients are most likely to benefit from specific therapies. By tailoring treatment strategies based on a patient’s unique multimodal profile, we aim to improve outcomes and offer new hope to those battling this difficult disease.”

The study will be presented as a poster by Ferdinandos Skoulidis, Department of Thoracic Medical Oncology, University of Texas MD Anderson Cancer Center at ESMO 2024 hosted in Barcelona, Spain from September 13-17, 2024. His presentation showcases the operational feasibility and clinical impact of large-scale multimodal analyses in identifying heterogeneous treatment effects in oncology.

For more information on SOPHiA GENETICS, visit SOPHiAGENETICS.COM, or connect on LinkedIn.

About SOPHiA GENETICS 
SOPHiA GENETICS (Nasdaq: SOPH) is a cloud-native healthcare technology company on a mission to expand access to data-driven medicine by using AI to deliver world-class care to patients with cancer and rare disorders across the globe. It is the creator of the SOPHiA DDM™ Platform, which analyzes complex genomic and multimodal data and generates real-time, actionable insights for a broad global network of hospital, laboratory, and biopharma institutions. For more information, visit SOPHiAGENETICS.COM and connect with us on LinkedIn.

SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures unless specified otherwise. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact support@sophiagenetics.com to obtain the appropriate product information for your country of residence. 

SOPHiA GENETICS Forward-Looking Statements: 
This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management’s beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements.

 

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Klook launches K.ai, an AI agent that manages merchants’ back-office operations

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K.ai goes beyond answering questions to executing inventory, pricing, and booking-related tasks in Klook’s merchant portal

SINGAPORE and HONG KONG, Nov. 3, 2026 /PRNewswire/ — Klook, a leading global platform for experiences, launches K.ai, an AI agent that helps experiences merchants manage their businesses by executing everyday tasks in Klook’s merchant portal.

Unlike conventional AI assistants that only answer questions or provide recommendations, K.ai can retrieve business information and act on merchants’ instructions, from checking bookings and availability to updating inventory and pricing. This reduces the need for merchants to navigate multiple menus and complete routine tasks manually.

K.ai is now being introduced to Klook’s merchants through a phased global rollout, ahead of the year-end travel season.

Bringing SMEs from offline to AI-powered operations

Experiences remain one of travel’s least digitized categories. According to Euromonitor, only about 34% of experiences bookings are made online, compared with 66% for accommodations and 81% for flights.

A key reason is fragmentation: small and medium-sized (SME) operators make up around 95% of the sector, and many lack the digital reach to sell beyond walk-ins and offline channels. The result is a large, fragmented supply base that travelers still struggle to find, compare and book online.

By bringing these merchants online, Klook makes them discoverable and bookable to travelers worldwide, and by embedding AI into Klook’s existing tech infrastructure, it helps them leapfrog from manual processes to AI-powered business management.

“Many experiences merchants don’t have dedicated teams to manage technology or back-office operations. With K.ai, we’re bringing the most practical and valuable agentic AI capabilities into their day-to-day operations, removing much of the manual work involved in running their businesses, so they can spend more time on what they do best: delivering meaningful experiences for travelers,” says Bernie Xiong, Co-founder and CTO of Klook.

From answering questions to getting work done

For SME merchants, managing bookings, inventory and pricing is essential but time-consuming. While most AI business assistants only answer questions, K.ai goes further — it answers questions and takes action.

A merchant can ask, “What did my bookings look like last week?” and receive a report. The merchant can then instruct K.ai to “Raise the weekend price by 10%” and have the change applied in the merchant portal.

Early results from merchants using K.ai demonstrate operational improvements. Tasks that required multiple steps can now be completed 95% faster for individual inventory and pricing updates, and 97% faster for batch checks of products, inventory and orders.

Beyond efficiency, merchants using K.ai recorded 3.4 times as many monthly bookings of those not using the agent. With the ability to adjust operational details in seconds, merchants are better equipped to respond to changing demand and capture booking opportunities.

“I used to block out an hour every morning to update prices and availability across my tours,” says Erica Yu, Co-founder of MyProGuide in Taiwan. “The difference is tangible. Now I tell K.ai what I want, and it’s done before my coffee is. I’m catching last-minute demand that I used to miss, and I finally have more time to work on the tours themselves.”

From back-office operations to business growth

Beyond supporting day-to-day merchant portal operations and queries, K.ai also simplifies other time-consuming aspects of running an experiences business.

With one-click product listing, merchants can upload existing materials and have K.ai generate structured product listings, pre-filling fields for merchants to review and edit instead of building listings from scratch.

K.ai also helps merchants make more informed business decisions by turning customer reviews and performance data into actionable insights.

Through the Reviews and Dashboard pages, K.ai highlights changes in business performance, identifies potential reasons behind them and surfaces opportunities for improvement. This helps merchants better understand customer needs, improve service quality and refine their offerings, shifting their focus from routine administration to growing their businesses.

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SOURCE Klook

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izmo Microsystems Successfully Develops and Qualifies Indigenous Pitch Detector for Defence Avionics

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Achievement demonstrates integrated electronics design, advanced semiconductor packaging and military grade manufacturing capabilities.

BENGALURU, India, Nov. 3, 2026 /PRNewswire/ — izmo Limited (NSE: IZMO) (BSE: 532341) today announced that its semiconductor subsidiary, izmo Microsystems Pvt. Ltd., has successfully developed and completed defence qualification of an indigenous Pitch Detector – a critical avionics component that senses aircraft pitch attitude and provides correction data to the gyromagnetic compass navigation system. The component is used across multiple military aircraft and helicopter platforms currently in active service.

The original foreign origin Pitch Detector faced irregular and limited supply from its overseas manufacturer, creating operational challenges for platforms dependent on it. izmo Microsystems undertook a complete indigenization program to develop a fully compatible Indian replacement, reducing dependence on imported components and strengthening domestic supply chain resilience.

izmo Microsystems successfully reengineered the original component without access to its design documentation, redesigned the electronics using modern technology, and manufactured a fully compatible replacement in India. The component was developed and manufactured at the Company’s DSIR recognised advanced semiconductor packaging facility in Bangalore, and successfully qualified to military reliability standard MIL-PRF-38534.

The achievement demonstrates izmo Microsystems’ ability to undertake complete product development programs, from design and engineering through manufacturing and qualification. These integrated capabilities position the Company to address a wider range of defence and aerospace indigenization opportunities, particularly where imported components are obsolete, difficult to procure or no longer supported by their original manufacturers.

The development also reflects the growing maturity of izmo Microsystems’ technology platform, which combines advanced electronics design with high reliability semiconductor packaging and manufacturing. These capabilities support the Company’s activities across defence, aerospace, silicon photonics and other advanced semiconductor applications.

India’s defence budget for FY2026–27 stands at ₹7.85 lakh crore, including ₹2.19 lakh crore for capital expenditure, reflecting the Government’s continued commitment to defence modernization and self reliance. With increasing emphasis on indigenous procurement and import substitution, izmo Microsystems sees growing opportunities to apply its engineering and manufacturing capabilities across the defence electronics sector.

About izmo Microsystems Pvt. Ltd.

izmo Microsystems Pvt. Ltd. is the advanced semiconductor packaging subsidiary of NSE/BSE listed izmo Limited. Based in Bengaluru, the Company operates a state-of-the-art facility providing integrated design, packaging and manufacturing services across silicon photonics, RF and microwave electronics, 3D System-in-Package integration, hermetic packaging and high reliability defence electronics.

For more information, visit  www.izmomicro.com / www.izmoltd.com or contact:   

Media Contact

izmomicro Communications

Email: info@izmomicro.com 

Investor Contact  

izmo Limited

No. 177/2C, Bilekahalli Industrial Area, Bannerghatta Road, Bangalore 560076

CIN: L72200KA1995PLC018734

Email ID: investors@izmoltd.com

Caution Concerning Forward- Looking Statements: Certain statements in this document may be forward-looking statements. Such forward-looking statements are subject to certain risks and uncertainties like regulatory changes, local political or economic developments, and many other factors that could cause our actual results to differ materially from those contemplated by the relevant forward-looking statements. Further, past performance is not necessarily indicative of future results. Given these risks, uncertainties and other risk factors, viewers are cautioned not to place undue reliance on these forward-looking statements. The Company will not be in any way responsible for any action taken based on such statements and undertakes no obligation to publicly update these forward-looking statements to reflect subsequent events or circumstances. 

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Auden Techno Corp. Recognized at Asia Pacific Enterprise Awards 2026 Taiwan Chapter for Strong Corporate Governance and Ethical Practices

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TAIPEI, Nov. 3, 2026 /PRNewswire/ — Auden Techno Corp., a Taiwan-based connectivity solutions provider established in 1981, has been recognized with the Corporate Integrity and Governance Excellence (CIGE) Award at the Asia Pacific Enterprise Awards (APEA) 2026 Taiwan, organized by Enterprise Asia. The recognition highlights the company’s continued commitment to integrity, responsible governance, and effective risk management as it advances connectivity solutions worldwide.

Led by Chairman and General Manager Daniel Chang, Auden Techno Corp. operates five business divisions covering Wireless Communications, Instrument Equipment Sales, Sustainability, mmWave, and Advanced R&D. Guided by its principles of “Integrity and Innovation”, the company places the Board of Directors at the center of its governance framework. In 2025, the Board convened eight meetings with a 97% attendance rate, while ESG oversight covering governance, information security, environmental protection, and social engagement was delegated to the Sustainable Development Committee. An independent Internal Audit Office reports quarterly to the Board and supports risk management across strategy, finance, compliance, and climate change.

Auden Techno Corp. has also embedded integrity into its organizational practices. All directors and senior executives have signed Integrity Management Declarations, while annual anti-corruption training is provided to all employees. An independent whistleblowing channel protects reporting parties, with zero violations recorded in 2025. Since 2025, ESG performance has also been linked to executive compensation with a 30% weighting.

The company’s governance framework is supported by measurable performance. It recorded zero information security incidents in 2025 and has maintained zero environmental violations, corruption incidents, and discrimination complaints for years. Its Corporate Governance Evaluation score of 91.30 placed it in the top tier for two consecutive years, demonstrating how integrity and governance have been integrated into its business operations.

These sustained efforts reflect Auden Techno Corp.’s commitment to embedding integrity, accountability, and responsible governance across its operations. Its consistent approach to ethical business practices and effective oversight demonstrates the strong governance foundation behind its recognition at the APEA 2026.

The APEA 2026 Taiwan is supported by the Taiwan Institute for Sustainable Energy (TAISE), with KPMG Taiwan as the Official Assurance Partner. PR Newswire serves as the Official News Release Distribution Partner while Commercial Times and Dailywire.asia serve as the Media Partners.

About Enterprise Asia

Enterprise Asia is a non-governmental organization in pursuit of creating an Asia that is rich in entrepreneurship as an engine toward sustainable and progressive economic and social development within a world of economic equality. Its two pillars of existence are investment in people and responsible entrepreneurship. Enterprise Asia works with governments, NGOs, and other organizations to promote competitiveness and entrepreneurial development, uplifting the economic status of people across Asia and ensuring a legacy of hope, innovation, and courage for future generations. Please visit https://www.enterpriseasia.org/ for more information.

About Asia Pacific Enterprise Awards

Launched in 2007, the Asia Pacific Enterprise Awards is the region’s most prestigious award for outstanding entrepreneurship, continuous innovation, and sustainable leadership. The Award provides a platform for companies and governments to recognize entrepreneurial excellence, hence spurring greater innovation, fair business practices, and growth in entrepreneurship. As a regional award, it groups together leading entrepreneurs as a powerful voice for entrepreneurship and serves as a by-invitation-only networking powerhouse. The program has grown to encompass 16 countries/ regions and markets all over Asia. For further information, please visit https://apea.asia/taiwan/. 

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SOURCE Enterprise Asia

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