Technology

Atomic Antibiotics Developed by Czech Scientists Counter Bacterial Resistance

Published

2 years ago

October 3, 2024

OSTRAVA, Czech Republic, Oct. 3, 2024 /PRNewswire/ — Scientists from Palacký University Olomouc (UP) and the Technical University of Ostrava (VSB-TUO), in collaboration with colleagues from China, have discovered a groundbreaking method for developing a new generation of antibiotics. These antibiotics not only combat a wide range of bacteria but also effectively prevent the development of bacterial resistance. By employing atomic engineering, the researchers transformed manganese—a trace element vital for human health—into a potent antibiotic by embedding it in the structure of chemically modified graphene. Tests conducted on animal models have demonstrated the material’s significant potential, particularly in localized therapies such as wound healing. The discovery has been published in the prestigious journal Advanced Materials, and the team has filed a European patent to safeguard their innovation.

“The material we developed successfully kills and inhibits the growth of all bacteria we studied, including highly resistant pathogens. It operates at low concentrations, which are completely harmless to human cells. Furthermore, bacteria cannot develop resistance to it, thus addressing one of modern medicine’s most pressing challenges. These promising results position atomic antibiotics for practical use in the near future,” said Radek Zbořil, a physical chemist and author of the research concept, who works at the Czech Advanced Technology and Research Institute (CATRIN UP) and the Centre for Energy and Environmental Technologies (CEET) at VSB-TUO.

A Frontal Attack with Manganese

In developing this antibiotic, the scientists drew on their expertise in graphene chemistry and atomic engineering, fields they have extensively studied in recent years. This time, they utilized a graphene derivative enriched with oxygen and nitrogen atoms, chemically incorporating manganese—a transition metal that is involved in metabolism, bone formation, blood sugar regulation and cellular protection against oxidative stress.

“We chose to target one of the strongest defences of bacteria—the carbohydrates in their cell walls and membranes, which are crucial for their survival. These carbohydrates play a protective role, facilitate substance transfer, enable communication with the environment, and serve as energy reserves. By chemically binding manganese to specific carbohydrate groups, we suppressed these critical functions, ultimately causing cell death. The graphene carrier plays an essential role by ensuring the delivery of manganese ions to the bacterial surface, which enables a direct chemical attack on the carbohydrate molecules,” Zbořil explained.

Effective Against Even the Most Resistant Bacteria

The new material also shows remarkable efficacy against bacteria that existing antibiotics struggle to combat. “We observed an excellent bactericidal effect against all bacteria from the ESCAPE group, which includes highly resistant bacterial pathogens. These bacteria are particularly dangerous because they are resistant to conventional antibiotics, which complicates treatment and increases the risk of severe infections, especially in hospital settings. The atomic antibiotic was the only agent that proved effective against all resistant bacteria, compared to commercial antibiotics,” said David Panáček, the first author of the paper, from CATRIN UP and CEET VSB-TUO.

The researchers tested the atomic antibiotic’s effect not only in laboratory settings but also in mouse models in collaboration with their Chinese colleagues. “In in-vivo tests, skin infections caused by resistant strains of Staphylococcus aureus (golden staph) healed quickly and effectively, with all markers of inflammation significantly reduced. We are now considering its use for wound dressings or antibacterial treatments on surfaces of artificial materials. There is tremendous potential to prevent bacterial biofilms from forming on devices such as artificial joint replacements, stents, or cannulas. Given its mode of action, this new material could also help prevent secondary infections, which would have a major impact on healthcare,” said Milan Kolář, a microbiologist and Dean of the Faculty of Medicine and Dentistry at Palacký University Olomouc, who played a key role in the research.

Atomic Antibiotics Open New Possibilities

The research team plans to continue exploring the material’s potential for systemic antibiotic treatments. “Some serious infections are now untreatable with existing antibiotics, and bacterial sepsis is becoming an increasingly common cause of death. We aim to test atomic antibiotics’ effectiveness in treating the most severe bacterial diseases,” Kolář added.

According to the United Nations, if bacterial resistance continues to rise at its current pace, by 2050 untreatable infections caused by multidrug-resistant bacteria could become the leading cause of death worldwide. These so-called ‘superbugs’ pose a global threat, necessitating the development of new antibacterial agents that can bypass the defence mechanisms bacteria use to protect themselves. This research, which also involved colleagues from the Faculty of Science at Palacký University Olomouc and two Chinese institutions, highlights the untapped potential of atomic engineering in addressing one of humanity’s most urgent scientific and social challenges.

Read the paper at: Single Atom Engineered Antibiotics Overcome Bacterial Resistance – Panáček – Advanced Materials – Wiley Online Library

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Technology

Club Offers for Travel Enthusiasts in Canada

Published

32 minutes ago

October 23, 2026

TORONTO, Oct 23, 2026 /PRNewswire/ — Travelzoo® (NASDAQ: TZOO), the club for travel enthusiasts, announces three of many new Club Offers for Club Members in Canada.

Rigorously vetted and negotiated for us travel enthusiasts:

$799—COSTA RICA WEEK WITH FLIGHTS & CAR
We think fall is an ideal time to visit Costa Rica; the scenery is lush and the crowds are gone. Drive between volcanic Arenal and the idyllic beaches of Tamarindo on this seven-night trip. Since it’s not as busy, we were able to negotiate a price that saves members up to $648 on departures through mid-December.

$899—BARCELONA: 5 NIGHTS WITH FLIGHTS
Explore Barcelona’s world-class museums and architectural masterpieces in the quieter winter months to pack more into your trip. You won’t waste hours in lines and can access top restaurants that are fully booked in summer. We save $300 on travel this January and February, when temperatures are still spring-like. Roundtrip flights from Toronto, hotel and daily breakfast are included.

$999—ST. KITTS GETAWAY FOR 2, REG. $2083
Most visitors to St. Kitts book months in advance, but when we pointed out that travel enthusiasts are more spontaneous, this resort gave us a terrific rate for stays this November and December. Spend four nights in Frigate Bay and get an upgraded Oceanview room, too.

Are you a travel enthusiast? Join the club today: https://travelzoo.com

Who are we?
We, Travelzoo®, are the club for travel enthusiasts. We reach 30 million travellers. Club Members receive Club Offers negotiated and rigorously vetted by our deal experts around the globe. Our relationships with thousands of top travel companies give us access to irresistible deals. Our club and its benefits are built around the lifestyle of a modern travel enthusiast.

Media Contact:
Amanda Ieraci – Toronto
+1 437 866 8540
aieraci@travelzoo.com

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SOURCE Travelzoo

Technology

Howard Hughes Holdings Set to Join S&P SmallCap 600

Published

2 hours ago

October 23, 2026

NEW YORK, Oct. 23, 2026 /PRNewswire/ — Howard Hughes Holdings Inc. (NYSE: HHH) will replace Arcosa Inc. (NYSE: ACA) in the S&P SmallCap 600 effective prior to the opening of trading on Wednesday, October 28. S&P 500 constituent CRH plc (NYSE: CRH) has acquired Arcosa in a deal that closed today, October 23.

Following is a summary of the changes that will take place prior to the open of trading on the effective date:

Effective Date

Index Name

Action

Company Name

Ticker

GICS Sector

October 28, 2026

S&P SmallCap 600

Addition

Howard Hughes Holdings

HHH

Real Estate

October 28, 2026

S&P SmallCap 600

Deletion

Arcosa

ACA

Industrials

ABOUT S&P DOW JONES INDICES

S&P Dow Jones Indices is the largest global resource for essential index-based concepts, data and research, and home to iconic financial market indicators, such as the S&P 500® and the Dow Jones Industrial Average®. More assets are invested in products based on our indices than products based on indices from any other provider in the world. Since Charles Dow invented the first index in 1884, S&P DJI has been innovating and developing indices across the spectrum of asset classes helping to define the way investors measure and trade the markets.

S&P Dow Jones Indices is a division of S&P Global (NYSE: SPGI), which provides essential intelligence for individuals, companies, and governments to make decisions with confidence. For more information, visit www.spglobal.com/spdji/en/.

FOR MORE INFORMATION:

S&P Dow Jones Indices
index_services@spglobal.com

Media Inquiries
spdji.comms@spglobal.com

View original content:https://www.prnewswire.com/news-releases/howard-hughes-holdings-set-to-join-sp-smallcap-600-302918511.html

SOURCE S&P Dow Jones Indices

Technology

Chelsea FC announces multi-year sleeve partnership with Sokin, the business payments and FX platform

Published

3 hours ago

October 23, 2026

Chelsea FC name fast-growing fintech platform as Principal Partner

LONDON, Oct. 23, 2026 /PRNewswire/ — Chelsea Football Club has today announced a multi-year partnership with Sokin, the embedded finance and payments company used by businesses worldwide. Sokin will be named a Principal Partner and Official Business Payments and FX Partner of Chelsea FC and Chelsea FC Women.

As a Principal Partner, Sokin will be represented on the sleeves of the Chelsea FC men’s, women’s and academy home, away, and third kits from the 2026/27 season.

The partnership brings together two ambitious London-headquartered organisations with worldwide reach – a club with millions of fans across the world and a fintech platform through which businesses move more than $11 billion a year. A club of Chelsea’s scale works in many currencies every day, with partners, competitions and supporters around the world, and needs a financial partner built to handle that.

Sokin gives finance teams business payments, multi-currency accounts, foreign exchange, checkout and treasury in one place, so they spend less time juggling banks and providers and keep more of what they move.

As Official Business Payments and FX Partner, Sokin will simplify how Chelsea FC sends, receives and manages money in the currencies the club operates in.

The Sokin logo will feature on the sleeve of the Chelsea shirt for the first time [when the men’s team host Tottenham Hotspur at Stamford Bridge on Saturday 24th October.]

Jason Gannon, President at Chelsea FC said:

“At Chelsea, we seek to partner with organisations that share our ambition and innovative mindset. Sokin’s expertise in business payments, and their focus on making both simpler for the businesses they serve, makes them a natural fit for the Club. We are pleased to welcome Sokin to the Chelsea family and look forward to working together in the years ahead.”

Vroon Modgill, CEO and founder at Sokin said:

“Chelsea plays on the biggest stage in world football, and its business runs in dozens of currencies. Sokin was built for that with regulated, multi-currency payments and foreign exchange for organisations that operate internationally. We’re proud to be the platform behind the business payments and FX of one of the most iconic teams in football. Sokin’s platform serves businesses in more than 170 countries. We’re thrilled to be partners for the season ahead. An organisation as sophisticated as Chelsea doesn’t leave its finances to chance.”

About Sokin

Sokin is the financial layer global business runs on. Businesses can transact, convert and hold money in 70+ currencies across 170+ countries. Some businesses use Sokin to manage global finance in-house. Others build it into their products to power financial experiences for their customers. Businesses move more than $9 billion a year on licenses Sokin holds in 36+ countries and infrastructure Sokin owns. Founded in 2019, Sokin has raised over $100 million from investors including Morgan Stanley Expansion Capital and Prysm Capital.

About Chelsea Football Club

Chelsea Football Club is one of the biggest, most successful football clubs globally and our men’s team are reigning world champions, having won the four-yearly FIFA Club World Cup in 2025. Our women’s team, Chelsea Women, are also multiple trophy winners.

Founded in 1905, Chelsea is London’s most central football club, based at the iconic 40,000-capacity Stamford Bridge stadium. Nicknamed the Blues, the club lifted the Champions League for the first time in 2012 and domestically has won the Premier League five times, the FA Cup eight times, the Football League Cup five times and the Football League Championship once, in 1955.

The Chelsea Women’s team have enjoyed a huge amount of success and in 2025 won the FA Women’s Super League for a sixth consecutive year and the eighth time overall. The Women’s FA Cup has been won on six occasions. We have also captured the FA Women’s League Cup four times as well as reaching the UEFA Women’s Champions League final in 2021. In two seasons, 2020/21 and 2024/25, a domestic treble of trophies was secured.

The Chelsea Foundation boasts one of the most extensive community initiatives in sport, helping to improve the lives of children and young people all over the world.

Media Contacts:

Taina Biggs
taina.biggs@sokin.com

Nerissa Chesterfield
nerissa.chesterfield@chelseafc.com

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