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Lupus Research Alliance Launches the DREAM Knowledge-Exchange Platform to Accelerate Precision Medicine in Lupus

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The DREAM is the final component of the Lupus Research Alliance’s Lupus Nexus, an innovative program that provides unprecedented resources to both researchers and those living with lupus

NEW YORK, Nov. 7, 2024 /PRNewswire/ — The Lupus Research Alliance (LRA) today launched the Data Repository, Exchange and Analytics platforM (DREAM), a cutting-edge knowledge-exchange platform. The DREAM consists of two distinct interfaces: a secure data-sharing and collaboration platform for researchers, and a research engagement platform for those living with lupus. The DREAM is the final component of the Lupus Nexus, a unique program that aims to accelerate precision medicine in lupus and is comprised of a Registry, a Biorepository, the DREAM, and a Quality Management System.

For researchers, the DREAM provides access to a rich source of longitudinal patient data (clinician and patient-reported), linked biospecimens, and amassed raw molecular data (from analyzed biospecimens) offering an unprecedented lupus resource for investigators.

For those living with lupus, the DREAM offers a sense of community and opportunities to connect, access educational resources, participate in research studies, and review and visualize their personal research data, including results of their biospecimen analysis, patient-reported outcomes over time, and more. It also provides a mechanism for those living with lupus to share feedback with the LRA and broader research community.  

A Key Component of LRA’s Lupus Nexus

Through the Lupus Nexus, investigators will have access to deep datasets and powerful tools to better understand the disease and will use that knowledge to help develop new treatments and improve the quality of life for those living with lupus.

“The launch of the DREAM completes our vision of the Lupus Nexus,” said Devon Kelly, Director, Lupus Nexus, Lupus Research Alliance. “The DREAM not only enables researchers to harness powerful data, but will better connect participants with research and information, creating a collaborative, data-driven path to benefit the entire lupus community.”

The Lupus Nexus is a key pillar of the newly announced LRA five-year Strategic Plan which aims to define disease heterogeneity, advance treatments from preclinical to clinical stages, increase diversity in research, and enhance clinical research capabilities. Over time, the Lupus Nexus will continue to expand its data and research capabilities, driving the development of more personalized treatments and empowering those living with lupus.

“Since lupus is such a complex and heterogeneous disease, developing new treatments hinges on access to high-quality data from diverse populations and increased collaboration among researchers and people with lupus,” said Peter Schafer, PhD, Co-Chair of the Lupus Nexus Steering Committee and Scientific Vice President at Bristol Myers Squibb. “The Lupus Nexus, with its DREAM platform, delivers unprecedented access to data and analytical tools, enabling researchers to accelerate the discovery and development of tailored treatments, at the same time enabling critical participation and feedback from the lupus community.”  

The LRA engaged research industry leaders Lifebit and Sano Genetics to build the DREAM. Lifebit, a global leader in genomics and health data software, will implement and manage the knowledge-exchange and analytics platform for researchers and clinicians, while Sano Genetics, a health tech company accelerating precision medicine research, will drive meaningful engagement by enabling those living with lupus to participate in research, access their research data and connect through an interactive online community.

The LRA will continue to develop and advance the Lupus Nexus as the preeminent program to transform lupus research and drug development through unprecedented information exchange capabilities. For more information, visit lupusnexus.org.

About Lupus
Lupus is a chronic, complex autoimmune disease that affects millions of people worldwide. In lupus, the immune system, meant to defend against infections, produces autoantibodies that mistake the body’s own cells as foreign, causing other immune cells to attack organs such as the kidneys, brain, heart, lungs and skin, as well as blood and joints. Ninety percent of people with lupus are women, most often diagnosed between the ages of 15-45. Black, Latinx, Indigenous, Asian and Pacific Islander people are disproportionately affected by lupus and more likely to experience severe lupus symptoms.

About the Lupus Research Alliance
The Lupus Research Alliance (LRA) is the largest non-governmental, non-profit funder of lupus research worldwide. The organization aims to transform treatment by funding the most innovative lupus research, fostering diverse scientific talent, and driving discovery toward better diagnostics, improved treatments and ultimately a cure for lupus. Because the LRA board of directors funds all administrative and fundraising costs, 100 percent of all donations support lupus research programs. Visit LupusResearch.org to learn more, and follow us on LinkedIn, Twitter, Facebook, and Instagram.

Thanks go to the following companies for their sponsorship support of the Lupus Nexus development: Bristol Myers Squibb, GSK, AbbVie Inc., and EMD Serono Inc.

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SOURCE Lupus Research Alliance

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Landis+Gyr Secures Major Contract with Leading US Utility

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CHAM, Switzerland and ALPHARETTA, Ga., Oct. 26, 2026 /PRNewswire/ — Landis+Gyr Group AG (SIX: LAND), a global energy technology leader driving intelligent innovation across the grid, today announced that it has secured a major contract with a leading US investor-owned electric utility. The agreement covers more than 3 million advanced metering endpoints.

Under the agreement, Landis+Gyr will provide Revelo meters and associated network and head-end system technologies, complemented by advanced security solutions, premium support, and software maintenance and services. The deployment is expected to advance the utility’s grid modernization objectives by enhancing security, grid visibility and operational performance.

“This important win reflects the strong momentum of our Grid Edge Intelligence portfolio and the trust customers place in Landis+Gyr to support large-scale grid modernization programs. By combining advanced metering, integrated technology, security and support capabilities, we look forward to helping this utility enhance grid visibility, reliability and operational performance,” said Peter Mainz, Chief Executive Officer of Landis+Gyr.

About Landis+Gyr

Landis+Gyr is a global energy technology leader, delivering intelligent solutions that connect devices, data, and decisions across the grid. Trusted by more than 2,000 utilities worldwide, we transform traditional devices into intelligent, networked sensors, giving utilities real-time grid visibility and system control. With these combined insights, electric, gas, and water companies can anticipate demand, optimize operations, and deliver energy that’s more reliable, resilient, accessible, safe, and sustainable for everyone. For more information, please visit our website www.landisgyr.com.

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In HelloNation, Electrical Expert Sean McGahy Breaks Down How a Whole Home Surge Protector Works

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The Article Explains How This Type of System Protects a Home’s Electronics From Power Surges Throughout the Day.

WAKE FOREST, N.C., Oct. 26, 2026 /PRNewswire/ — What does a whole home surge protector do? A HelloNation article answers that question and explains how this type of device defends a home’s wiring and electronics from voltage spikes.

The article explains that many power surges happen quietly throughout the day, often without anyone noticing. Large appliances such as air conditioners and refrigerators create small voltage spikes every time they cycle on and off.

According to the article, a whole home surge protector is installed directly at the electrical panel, where it can monitor voltage across the entire house. Unlike a power strip, which protects a single outlet, this device works at the source.

The article notes that modern homes rely on sensitive electronics, including smart thermostats, entertainment systems, and connected appliances. Repeated voltage fluctuations can damage this circuitry over time, even when a homeowner never notices it happening.

External surges from lightning strikes or utility grid fluctuations tend to be more severe than everyday cycling surges, the article explains. A whole home system is designed to respond quickly and redirect excess voltage away from a home’s circuits.

Installation is typically straightforward for a licensed electrician and does not usually require major changes to existing wiring, the article states. Many systems include indicators that let homeowners confirm the device is functioning properly.

The article points out that surge protectors are rated by how much energy they can absorb, often measured in joules. Homes with more electronics generally benefit from a protector with a higher rating.

A protector does not last forever, the article notes. Absorbing a large surge can wear down its internal components, even if the device still looks functional. Periodic testing by an electrician can confirm the system is still working as intended.

Electrical Expert Sean McGahy of Zar Electric is featured in the article. The article explains how periodic testing can confirm that a whole home surge protector is still providing the level of protection it was designed for.

The article adds that surge protection works best as one part of a broader approach to electrical safety. Homes should still have properly functioning breakers, updated wiring, and routine inspections alongside this added layer of defense.

Homes in areas prone to storms or frequent power fluctuations may see added value from this protection, the article notes. New construction offers a convenient time to add it, though retrofitting an existing home is described as achievable and usually quick.

The article notes that cost varies depending on the type of system installed and the complexity of a home’s existing electrical setup. Many homeowners view the expense as reasonable compared to the potential cost of replacing damaged electronics after a serious surge event.

Some insurance providers take note of these systems when evaluating a home’s overall risk profile, the article adds, though policies vary from carrier to carrier. This is described as one more reason homeowners weigh the value of this type of protection.

The article closes by noting that deciding whether this protection makes sense often comes down to a home’s electronics, its location, and a homeowner’s comfort level with risk. A licensed electrician can walk through these considerations before a final decision is made.

How Does Whole Home Surge Protection Safeguard Your Home? features insights from Sean McGahy, Electrical Expert of Wake Forest, North Carolina, in HelloNation.

About HelloNation

HelloNation is America’s Good News Network, a premier media platform built on the idea that good news travels faster when real people tell real stories. Through its community-focused digital publications and innovative “edvertising” approach, HelloNation delivers expert-driven, good-news content that informs, inspires, and spotlights the leaders making a meaningful impact in their communities.

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SOURCE HelloNation

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In HelloNation, Building Materials Expert Andy Maetzold Explains How Freeze-Thaw Cycles Affect Minnesota Homes

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The Article Shows How Moisture, Temperature Swings, and Hail Shape Material Choices for Roofs, Windows, Walls, and Decks.

WACONIA, Minn., Oct. 26, 2026 /PRNewswire/ — How do freeze-thaw cycles damage a home in Minnesota? The answer appears in a HelloNation article that was newly published for homeowners choosing building materials for a cold climate. The article features insights from Building Materials Expert Andy Maetzold, a fourth-generation member of the family behind Mayer Lumber.

The HelloNation article explains that a Minnesota home faces a wider range of weather than houses in most of the country. Below-zero nights, humid summers, and hailstorms all test the products used to build and repair it.

According to the article, moisture often does more harm than cold by itself. Water seeps into small gaps, freezes overnight, and expands, and repeated freeze-thaw cycles slowly push joints and seams apart.

The article also notes that large temperature swings make many products expand in summer and shrink in deep cold. Materials installed without room to move can buckle, crack, or pull loose from their fasteners.

The roof takes more of this stress than any other part of the house, the article explains. Asphalt shingles remain the most common choice because they are affordable and familiar to most roofing crews. In areas that see hail, many homeowners look at impact-resistant shingles that earn a Class 4 rating.

The article points out that some insurance companies offer lower premiums for Class 4 roofs, though discount rules vary by insurer. Metal roofing is another option that sheds snow quickly, and snow guards are often added above doors and walkways.

Ice dams get special attention in the piece. The article explains that no shingle stops them alone, because the real cause is warm air leaking into the attic and melting snow on the upper roof. Air sealing, attic insulation, and steady ventilation deal with that heat directly.

Cold-climate building codes also call for an ice barrier membrane under the shingles along the eaves, according to the article. This layer helps keep backed-up water away from the roof deck and the ceilings below.

For windows, the article points readers to the National Fenestration Rating Council label and its U-factor, which measures how easily heat passes through the whole unit. A lower number means better insulation and a warmer glass surface on a January night.

The article compares double-pane windows with triple-pane units, which cut heat loss further but cost and weigh more. It also notes that vinyl and fiberglass frames insulate well, while aluminum frames need a thermal break to suit Minnesota winters.

Walls, decks, and lumber are covered as well. The article explains that house wrap and flashing protect wall framing from water, and that wood touching concrete or soil generally needs pressure treatment.

The insights from Building Materials Expert Andy Maetzold also address cost. The article encourages comparing the full life of a product rather than the purchase price alone, since a cheaper material that needs frequent repairs can cost more over 20 or 30 years.

Finally, the article advises checking with local building officials about code rules. It also stresses following manufacturer installation instructions, since many warranties depend on them.

How Do Freeze-Thaw Cycles Affect Building Materials in Minnesota? features insights from Andy Maetzold, Building Materials Expert of Waconia, Minnesota, in HelloNation.

About HelloNation

HelloNation is America’s Good News Network, a premier media platform built on the idea that good news travels faster when real people tell real stories. Through its community-focused digital publications and innovative “edvertising” approach, HelloNation delivers expert-driven, good-news content that informs, inspires, and spotlights the leaders making a meaningful impact in their communities.

View original content to download multimedia:https://www.prnewswire.com/news-releases/in-hellonation-building-materials-expert-andy-maetzold-explains-how-freeze-thaw-cycles-affect-minnesota-homes-302919645.html

SOURCE HelloNation

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