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Startup ProFuse Launches Pioneering Drug Discovery Platform for the Prevention of Muscle Loss

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YOKNEAM ILLIT, Israel, April 3, 2025 /PRNewswire/ — Israeli startup ProFuse Technology, which specializes in the cultivation of muscle tissue in laboratory conditions, has launched a new technology and program for discovering drugs that prevent muscle mass loss caused by the growing use of GLP-1 weight-loss injections, aging, and cancer.

ProFuse’s technology is based on developing methods to generate highly mature muscle tissues that accurately reflect the structure and function of natural human muscle. The company is now applying this technology to discover new drug candidates and to predict with high accuracy which molecules have the potential to gain regulatory approval as new therapies for preventing and restoring muscle mass.

The process utilizes advanced automation to efficiently screen potential drug candidates. This represents a breakthrough compared to existing technologies, which rely on conventional models with limited predictive power—necessitating extensive animal testing. ProFuse’s technology enables precise testing of a large number of molecules, thereby streamlining the research process and significantly reducing time, resources, and costs.

The demand for muscle-preserving therapies is rapidly increasing. GLP-1 weight-loss treatments are expected to grow significantly by 2030, but unintended muscle loss associated with these drugs poses a significant health concern.

Another key area for muscle preservation drugs is sarcopenia, or age-related muscle loss, which affects approximately 10% to 16% of individuals over 50—equating to around 13 million to 20 million Americans. Sarcopenia contributes to increased frailty and is linked to significant healthcare costs. Additionally, a major indication for such therapies is cancer cachexia, a condition affecting a growing number of advanced-stage cancer patients. Cancer cachexia leads to severe muscle wasting, physical decline, and reduced treatment success.

ProFuse was founded in 2021 by Professor Eldad Tzahor and Dr. Tamar Eigler-Hirsh from the Weizmann Institute of Science (CTO), along with Guy Nevo-Michrowski, who serves as the company’s CEO. Dr. Eigler-Hirsh and Prof. Tzahor, in collaboration with Dr. Ori Avinoam, identified the natural process responsible for muscle regeneration and repair. This discovery paved the way for the development of an innovative technology that enables the efficient cultivation of highly mature muscle fibers under laboratory conditions.

Over four years, this technology positioned ProFuse as a leading company in the global cultivated meat industry. Two years ago, ProFuse began leveraging its muscle cultivation technology for additional applications, and it has recently expanded into drug discovery

ProFuse also announces today the appointment of Anat Naschitz to its Board of Directors. Naschitz is a prominent investor and entrepreneur in the life sciences field, with nearly 30 years of experience in founding, managing, and investing in companies and venture capital funds. Throughout her career, she has collaborated with leading industry players, from major pharmaceutical companies to cutting-edge biotech firms. Notably, Naschitz co-founded and co-led OrbiMed Israel, part of the global healthcare investment firm managing approximately $20 billion.

Anat Naschitz: “I am grateful to ProFuse for the opportunity to be part of the journey in discovering and developing drugs that prevent muscle mass loss —an important clinical need requiring a solution. I was impressed by the company’s and management’s ability to demonstrate resilience in the face of challenges requiring adaptation and change. This adaptability was evident both at the industry level—strategically pivoting toward new directions—and at the operational level, where the company exhibited remarkable flexibility, strategic decision-making, and an unwavering positive spirit.”

“ProFuse’s timing for entering the market is excellent,” said Guy Nevo-Michrowski, CEO and co-founder of the company. “Weight-loss drugs lead to muscle mass loss, prompting pharmaceutical companies to invest significant resources in developing innovative treatments that combine GLP-1 weight-loss drugs with muscle mass preservation therapies. As a result, several major deals in the muscle preservation drug sector have been signed in recent years, with transaction values reaching several billion dollars. This trend signals a significant window of opportunity for new technologies in this field, including ours.”

ProFuse was established under the Fresh Start incubator and has raised approximately $8 million to date, including $3 million in grants from the European Union and the Israel Innovation Authority, as well as $5 million from Israeli and U.S. funds (OurCrowd and Green Circle Capital), alongside investments from Tnuva, Tempo, and private investors.

Images can be downloaded here.

For more information about ProFuse: https://profuse-tech.com

Media contact:
Amir Ben Artzi
Meirovitch PR
amir@meirovitch.com

 

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SOURCE ProFuse Technology

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Aura Q3 2026 Earnings Call and Quarterly Results

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BOSTON, Oct. 18, 2026 /PRNewswire/ — Aura (ASX: AXQ), a global leader in online safety and wellbeing, will release its Q3 2026 financial results on Thursday, 12th November 2026 prior to the ASX market opening. In addition, Aura will also release its Appendix 4C and Quarterly Activities Report for the quarter ended 30 September 2026 on Friday, 30th of October.

The company will host a webcast at 10:30 AM AEDT on Thursday, 12th November 2026 to discuss its financial results for Q3 and business outlook.

Q3 2026 Earnings Call Details

November 12, 2026 10:30am AEDT | November 11, 2026 6.30pm ESTLink to register: https://events.q4inc.com/attendee/159132282

A replay of the webcast will be available on Aura’s investor relations website at investors.aura.com.

The release of this announcement was authorized by William Lundregan, Chief Legal Officer and Secretary at Aura. 

Investor Relations:
ir@aura.com 

Press Contact:
media@aura.com 

About Aura

Aura (ASX: AXQ) is a global leader in online safety and wellbeing. Built on the belief that people deserve a trusted, always-on layer of protection, Aura’s AI-powered platform delivers protection for individuals, families and enterprises– from proactive protection against identity theft, financial fraud and online threats to tools that help schools and parents protect children from cyberbullying, harmful content, and threats to their wellbeing. Aura’s platform spans the environments that matter most– home, school and work– empowering people of all ages with end-to-end protection for every aspect of online life. Learn more at aura.com.

CATEGORY: Financial News

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SOURCE Aura

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Faith: The Spark Born by the Yudu Riverside

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BEIJING, Oct. 18, 2026 /PRNewswire/ — An interview from China.org.cn with Wang Xiaohui and David Ferguson on the Long March:

David Ferguson:

This is the Yudu River. One dusk in October, 1934, more than 86,000 soldiers of the Red Army crossed this river and embarked on the Long March, a two-year saga that has left its mark in history.

Yet, lingering here by the river, I am struck by a simple question: If you have faith in a bright future, and reality seems to thwart you at every turn, where do you find the moral strength to keep believing?

Wang Xiaohui:

At dusk on Oct. 17, 1934, an army of more than 86,000 troops gathered along the banks of the Yudu River. Over 800 boats of all sizes floated on the water, bound together with planks collected from villagers’ home gates, timber beams, and even coffin boards reserved for elderly locals. The people of Yudu built this pontoon bridge, determined to help the army led by the Communist Party of China (CPC) cross the river.

At that time, no one knew that the great expedition embarked upon by the banks of the Yudu River would go on to transform China and exert far-reaching influence across the world.

China in the 1920s and 1930s was plagued by chaos and despair.

The Kuomintang (KMT), the ruling party back then, was not capable of unifying the nation, leaving warlords locked in endless fighting. In 1931, Japanese invaders launched an assault on northeastern China, beginning their invasion. Crushed under domestic turbulence and foreign aggression, countless civilians were displaced, with many even starving to death on the streets; in certain regions, severe drought resulted in zero harvests, yet the farmers were forced to pay land taxes assessed for more than a decade into the future.

Amid this turmoil, the only glimmer of hope for the Chinese nation was kindled by the revolution ignited by the Communist Party of China.

The CPC, dedicated to winning liberation for the people and national independence, built contingents of workers’ and peasants’ Red Army troops and revolutionary base areas across the countryside. Impoverished farmers were granted land ownership, as well as unprecedented political dignity. On Nov. 7, 1931, the Chinese Soviet Republic was officially proclaimed in Ruijin, then a small village in southeastern China’s Jiangxi Province, establishing a Soviet system under which workers, peasants and soldiers elected representatives to run regional affairs and make policies.

The communist ideal of a fair society free from exploitation and equality for all blazed like a spark in the darkness; it kindled hopes among impoverished Chinese and became the wellspring of faith that enabled the Red Army — a force made up of poor workers and peasants — to overcome all hardships in the days to come.

Yet, bright as the spark was, it burned thin and fragile at times. Could this flame still endure when the ideals it carried were repeatedly battered by harsh reality?

In September 1933, flocks of warplanes clouded the skies over the Red Army’s revolutionary base areas. By then, Japanese invaders were steadily advancing towards North China, but Chiang Kai-shek’s KMT turned a blind eye to the looming national crisis. They mobilized over a million troops and more than 200 aircraft to launch a massive offensive at the Red Army’s base areas. Over the previous three years, Chiang Kai-shek had mounted four major military “encirclement” campaigns aimed at exterminating the Red Army, but all ended in failure. He was desperate for a pivotal victory to restore his prestige and to wipe out the CPC and the Red Army.

At the time, the commander of the Red Army abandoned mobile warfare tactics pioneered by Mao Zedong and other commanders, opting instead for rigid positional warfare involving conventional head-on clashes. But the reality was, some Red Army units didn’t even possess a single light machine gun; how could they confront the heavily-armed KMT army head-on?

Zhong Ming, a Red Army medic, could never erase the memories of gravely wounded soldiers being carried to his aid station. He remembered how a soldier whose chest was blown open begged his comrades to end his life. At the frontline, a whole battalion of Red Army soldiers religiously followed orders to defend crude earth-and-wood bunkers, but under the constant barrage of KMT artillery and airstrikes, every soldier in the battalion laid down their lives; not a single man survived.

What’s more heart-wrenching is that no matter how fearlessly the Red Army fought, the steep imbalance in military strength, paired with erroneous military command led to irreversible losses. By October 1934, the KMT’s iron-clad encirclement closed menacingly around Ruijin.

Faced with this dead-end, what decision would you make?

This stood as the most agonizing decision for the Red Army. The biggest challenge lay not in sacrificing one’s life for an ideal, but in finding a way to keep the revolutionary cause alive.

To stay meant defeat — the Red Army had no room to maneuver within the Central Revolutionary Base Area. To break through the encirclement, however slim the odds, offered a fighting chance. Preserving the Red Army as a living force mattered much more than clinging to isolated strongholds. Where the spark survives, the path ahead remains lit.

The air already turned chilly in October. Units of the Central Red Army assembled in Yudu to prepare for a strategic shift. The plan was kept strictly classified; none of the soldiers knew they were evacuating the base areas, only sensing an unusual vibe.

At dusk on Oct. 17, crowds lined up at the Yudu riverbank. Tens of thousands of villagers flocked from every corner to see the Red Army off. They walked alongside the marching columns, slipping food like eggs and glutinous rice balls into the soldiers’ pockets, praying for their swift homecoming.

The main force of the Central Red Army set off. Within days, they left behind revolutionary base areas where they had survived, grown and taken root. No one anticipated that the journey they embarked on would become the Long March, a trek spanning over 10 provinces. Still less could anyone imagine that this journey would ultimately pave the way for a brand-new China.

Looking back on this chapter of history, many claim that the Red Army only set out on this expedition because the enemies left them no other choice. To a degree, yes, the Long March was indeed a forced strategic shift, yet this fact does nothing to diminish its greatness and glory.

The ordinary Red Army soldiers had no idea how far they would march, or where they were heading. But they clung firmly to their founding mission: to deliver liberation for the people and independence to the nation. This unswerving conviction kept them from disintegrating through countless perils, sustaining them as they marched into the unknown with resolve.

David Ferguson:

I now realize that faith and ideals untested by harsh reality may have no true substance.

Since its founding, the Communist Party of China has always upheld the realization of communism as its fundamental goal. Despite devastating losses and extreme adversity, the Red Army continued to press forward resolutely and never faltered. Its inner strength came from an unshakable belief in the cause, an unwavering commitment to the founding aspiration, and a profound sense of mission. The Red Army was never fleeing pursuers in search of safety; it was marching forward to a future in which it had a steadfast belief.

Wang Xiaohui:

The Long March went on for two years. The Red Army trekked 25,000 li across some of China’s harshest terrain, but they kept their heads high, seeking hope amid despair and marching towards light through unending darkness. The lofty ideals and sense of mission they upheld have also become the torch that guides generations of CPC members in the following centennial, tempering them into steel as they press forward unswervingly toward national rejuvenation.

That spark lit along the Yudu River has never dimmed since.

China Mosaic
http://www.china.org.cn/video/node_7230027.htm

Faith: The Spark Born by the Yudu Riverside
http://www.china.org.cn/2026-10/16/content_118736835.shtml

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SOURCE China.org.cn

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Linktel Technologies Highlights Breakthrough 1.6T LPO Performance & Strong Market Pull at OCP 2026

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SAN JOSE, Calif., Oct. 18, 2026 /PRNewswire/ — At the recent 2026 OCP Global Summit, Linktel Technologies showcased its cutting-edge optical interconnect portfolios engineered specifically for next-generation AI computing networks. Among the heavy lineup, Linktel’s 1.6T Linear Pluggable Optics (LPO) solutions commanded immense industry attention, drawing heavy customer interest for their unprecedented energy efficiency, ultra-low latency, and supply-chain resilience.

Spotlight: 1.6T LPO Performance & High Customer Traction

AI data centers face immense scaling pressures, demanding higher bandwidth densities with tighter thermal and power budgets. Linktel’s 1.6T LPO solutions—highlighted by the 1.6T LPO 2DR4—delivered standout performance metrics that captured the spotlight at the summit:

Ultra-Low Power Consumption: Operates with power consumption as low as an impressive 10W, drastically mitigating data center cooling and power loads.Minimal Latency: Features a linear optics architecture that cuts down signal processing delays, making it a critical asset for high-performance AI scale-out fabrics.Enhanced Supply-Chain Resilience: Eliminating the optical DSP mitigates component choke points, ensuring robust scalability for mass deployments.Proven Interoperability: Following its breakthrough performance and multi-switch platform interoperability at the early September 2026 1.6T LPO-MSA Plugfest, Linktel has laid a solid foundation for the 200G-per-wavelength ecosystem.

Surging Market Interest

Throughout OCP 2026, Linktel’s live demonstrations of its 1.6T LPO, LRO, and FRO modules drew crowds of data center architects and industry partners. With volume production already in place, Linktel is fully equipped to meet the exploding market demand for energy-efficient, high-density 1.6T connectivity.

Overview of Other Innovations at OCP 2026

In addition to the heavily requested 1.6T LPO lineup, Linktel showcased two other major high-speed architectural pillars:

12.8T Liquid-Cooled XPO:Featured a live thermal demonstration integrating advanced liquid cooling to guarantee stable operations in high-density AI nodes.As a founding member of the XPO MSA, Linktel is actively scaling XPO series with FRO, LRO, and LPO variants for comprehensive scale-up, scale-out, and scale-across frameworks.6.4T/7.2T NPO Modules:Displayed with covers removed to reveal internal architectural designs supporting both ELS and ILS configurations.Combines compact high density with low power and low latency, backed by an established 6.4T/7.2T NPO roadmap.DMD Technology & Executive Presentation:Linktel Engineer Director Dr. Grace Zhang hosted a heavily attended Executive Session titled “Dispersion Managed Transceiver for Next-Gen AI Fabrics,” detailing cost-effective 800G (20km) and 1.6T (10km) solutions for OCS SuperPOD architectures, as well as the feasibility of 400G per lambda (3km).With its DMD product line already in volume production, Linktel actively calls upon ecosystem partners to join forces in collaborative development. To drive ecosystem maturity, Linktel is open to sharing its U.S.-filed patents, paving the way for industry-wide adoption and advancements in next-gen AI fabrics.

About Linktel Technologies

Linktel Technologies is a global leader in optical transceiver development and manufacturing, supplying high-speed optical I/O connectivity—including pluggable transceivers, optical engines, and ODM/JDM services.

For more information, visit www.linktel.com or follow Linktel Technologies on LinkedIn.

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SOURCE Linktel Technologies

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