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Startup ProFuse Launches Pioneering Drug Discovery Platform for the Prevention of Muscle Loss

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2 years ago

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YOKNEAM ILLIT, Israel, April 3, 2025 /PRNewswire/ — Israeli startup ProFuse Technology, which specializes in the cultivation of muscle tissue in laboratory conditions, has launched a new technology and program for discovering drugs that prevent muscle mass loss caused by the growing use of GLP-1 weight-loss injections, aging, and cancer.

ProFuse’s technology is based on developing methods to generate highly mature muscle tissues that accurately reflect the structure and function of natural human muscle. The company is now applying this technology to discover new drug candidates and to predict with high accuracy which molecules have the potential to gain regulatory approval as new therapies for preventing and restoring muscle mass.

The process utilizes advanced automation to efficiently screen potential drug candidates. This represents a breakthrough compared to existing technologies, which rely on conventional models with limited predictive power—necessitating extensive animal testing. ProFuse’s technology enables precise testing of a large number of molecules, thereby streamlining the research process and significantly reducing time, resources, and costs.

The demand for muscle-preserving therapies is rapidly increasing. GLP-1 weight-loss treatments are expected to grow significantly by 2030, but unintended muscle loss associated with these drugs poses a significant health concern.

Another key area for muscle preservation drugs is sarcopenia, or age-related muscle loss, which affects approximately 10% to 16% of individuals over 50—equating to around 13 million to 20 million Americans. Sarcopenia contributes to increased frailty and is linked to significant healthcare costs. Additionally, a major indication for such therapies is cancer cachexia, a condition affecting a growing number of advanced-stage cancer patients. Cancer cachexia leads to severe muscle wasting, physical decline, and reduced treatment success.

ProFuse was founded in 2021 by Professor Eldad Tzahor and Dr. Tamar Eigler-Hirsh from the Weizmann Institute of Science (CTO), along with Guy Nevo-Michrowski, who serves as the company’s CEO. Dr. Eigler-Hirsh and Prof. Tzahor, in collaboration with Dr. Ori Avinoam, identified the natural process responsible for muscle regeneration and repair. This discovery paved the way for the development of an innovative technology that enables the efficient cultivation of highly mature muscle fibers under laboratory conditions.

Over four years, this technology positioned ProFuse as a leading company in the global cultivated meat industry. Two years ago, ProFuse began leveraging its muscle cultivation technology for additional applications, and it has recently expanded into drug discovery

ProFuse also announces today the appointment of Anat Naschitz to its Board of Directors. Naschitz is a prominent investor and entrepreneur in the life sciences field, with nearly 30 years of experience in founding, managing, and investing in companies and venture capital funds. Throughout her career, she has collaborated with leading industry players, from major pharmaceutical companies to cutting-edge biotech firms. Notably, Naschitz co-founded and co-led OrbiMed Israel, part of the global healthcare investment firm managing approximately $20 billion.

Anat Naschitz: “I am grateful to ProFuse for the opportunity to be part of the journey in discovering and developing drugs that prevent muscle mass loss —an important clinical need requiring a solution. I was impressed by the company’s and management’s ability to demonstrate resilience in the face of challenges requiring adaptation and change. This adaptability was evident both at the industry level—strategically pivoting toward new directions—and at the operational level, where the company exhibited remarkable flexibility, strategic decision-making, and an unwavering positive spirit.”

“ProFuse’s timing for entering the market is excellent,” said Guy Nevo-Michrowski, CEO and co-founder of the company. “Weight-loss drugs lead to muscle mass loss, prompting pharmaceutical companies to invest significant resources in developing innovative treatments that combine GLP-1 weight-loss drugs with muscle mass preservation therapies. As a result, several major deals in the muscle preservation drug sector have been signed in recent years, with transaction values reaching several billion dollars. This trend signals a significant window of opportunity for new technologies in this field, including ours.”

ProFuse was established under the Fresh Start incubator and has raised approximately $8 million to date, including $3 million in grants from the European Union and the Israel Innovation Authority, as well as $5 million from Israeli and U.S. funds (OurCrowd and Green Circle Capital), alongside investments from Tnuva, Tempo, and private investors.

Images can be downloaded here.

For more information about ProFuse: https://profuse-tech.com

Media contact:
Amir Ben Artzi
Meirovitch PR
amir@meirovitch.com

 

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SOURCE ProFuse Technology

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2026 Canton Fair Design Award Winners Showcase China’s Innovation Strength

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15 minutes ago

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October 19, 2026

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GUANGZHOU, China, Oct. 19, 2026 /PRNewswire/ — As the 140th Canton Fair opens, the winners of the 2026 Canton Fair Design Award (CF Award) have also been announced. Winning products are now on display in Area D of the Canton Fair Complex, offering visitors a closer look at some of the latest advances in Chinese manufacturing and industrial design.

Among this year’s top honorees, a domestically developed high-performance sport motorcycle and an intelligent navigation capsule robot gastric endoscopy system received the Best of the Best Award, the competition’s highest recognition.

The Canton Fair also enhanced the visitor experience with a themed showcase area within the award exhibition. Built around four application-oriented concepts, namely Outdoor Pleasure, Smart Living, Cozy Home and Kitchen Elegance, the immersive displays demonstrate how innovative designs can be integrated into everyday life, helping visitors better understand the practical value behind these award-winning products.

This year, 4,218 products from 2,112 companies competed for the award. Following multiple rounds of evaluation, 222 products from 174 companies were selected.

The award-winning products reflect several key trends shaping the next stage of Chinese manufacturing. Innovation remains a defining theme, with breakthrough technologies ranging from upper limb motor function assistance and enhancement system to exoskeleton robots, underscoring the growing momentum of high-end manufacturing.

Meanwhile, intelligent technologies continue to gain traction across industries. Smart products account for more than 30% of this year’s winners, with AI-powered glasses, intelligent conference terminals and smart healthcare devices extending AI applications across home, office, medical and outdoor environments.

Sustainability is also becoming increasingly embedded throughout the product lifecycle. Green products represent over 40% of the winning entries, while innovations such as integrated energy-saving panels and sugarcane paper demonstrate how environmentally conscious practices are being incorporated into product design, materials selection and manufacturing processes.

Established in 2013, the Canton Fair Design Award is widely regarded as a benchmark for design innovation in China’s foreign trade sector. The award recognizes products that combine design excellence with commercial value, promoting the transformation and upgrading of Chinese manufacturing and supporting high-quality trade development. Entries are evaluated across five dimensions: innovation, quality, functionality, aesthetics and sustainability.

For more convenient attendance, please click here for pre-registration:
https://buyer.cantonfair.org.cn/register/buyer/email?source_type=16

 

View original content to download multimedia:https://www.prnewswire.com/news-releases/2026-canton-fair-design-award-winners-showcase-chinas-innovation-strength-302911954.html

SOURCE Canton Fair

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InstaMall Launches Same-Day Fashion Delivery Experience, Bringing 80+ Brands to Shoppers’ Doors in Miami

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16 minutes ago

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October 19, 2026

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First-of-its-kind shopping app pairs artificial intelligence with same-day delivery, bringing luxury
and contemporary brands directly to customers’ doorsteps 

Featured luxury and contemporary brands include AllSaints, John Varvatos and Aritzia

MIAMI, Oct. 19, 2026 /PRNewswire/ — InstaMall, a first-of-its-kind shopping app offering same-day delivery and access to real-time inventory across luxury and contemporary fashion, launches today in Miami, Florida. Now available via iOS and Android, InstaMall provides access to more than 80 contemporary and luxury fashion brands across Miami’s five premier retail clusters, including Balmain, Louis Vuitton, Bottega Veneta, Ganni, Coach, Diesel, Reformation, Aritzia, Cult Gaia, Prada and more. InstaMall will add more brands within the app in the coming weeks and seasons. 

Sitting at the intersection of fashion, technology and commerce, InstaMall brings inspiration and purchase together through a more dynamic way to discover and shop for fashion. The experience combines access to luxury and contemporary brands with the convenience of same-day delivery, bringing the speed customers have come to expect across categories like food and groceries to fashion while maintaining the brand experience retailers and shoppers expect.

Within the app, customers will have access to InstaMall’s AI-powered stylist and virtual try-on features, making it easier to browse, discover and shop styles online. InstaMall’s AI Stylist serves as an intelligent shopping assistant that responds to customers’ preferences in real time. Customers can use the AI Stylist to receive product recommendations, build outfits, ask questions and discover new styles, while its virtual try-on feature allows them to visualize select items on themselves before making a purchase.

“InstaMall was founded on the belief that the convenience customers have come to expect from same-day delivery should extend to the way they shop for fashion,” said Elliot Aboud, Founder and CEO of InstaMall. “As fashion and technology continue to evolve together, we saw an opportunity to create a more seamless shopping experience that brings customers closer to the brands they love, combining a curated assortment, AI-powered styling and virtual try-on with the ease and convenience of same-day delivery.”

Prior to founding InstaMall, Elliot Aboud helped build the Aroma360 and Hotel Collection brands, overseeing the launch of the first retail store and expanding the retail footprint to more than 30 stores across the United States and two in Dubai. InstaMall is bringing fashion and luxury to the next generation with its seamless shopping experience and wide selection of brands.

Customers can download InstaMall through the Apple App Store or Google Play, or by going to instamall.co.

About InstaMall 

InstaMall is a same-day fashion shopping and discovery app reimagining how consumers shop for luxury and contemporary brands. Sitting at the intersection of fashion, technology and commerce, InstaMall brings inspiration and purchase together in an experience that gives consumers a more dynamic way to discover and shop. Where on-demand delivery has long existed for categories like food and groceries, InstaMall brings that same convenience to luxury fashion for the first time, delivering the same day without compromising the brand experience fashion retailers and their customers expect. The company launched publicly in Miami on October 16, 2026, and plans to expand nationally. For more information, please visit instamall.co.

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SOURCE InstaMall

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PTC to Announce Fourth Fiscal Quarter and Full Year 2026 Results on Wednesday, November 4, 2026

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16 minutes ago

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October 19, 2026

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BOSTON, Oct. 19, 2026 /PRNewswire/ — PTC (NASDAQ: PTC) will release its fiscal 2026 fourth quarter and full year results on Wednesday, November 4th after the stock market closes. As previously announced on October 5th, 2026, PTC entered into a definitive agreement to be acquired by Schneider Electric. In light of the pending transaction, PTC is suspending quarterly earnings conference calls and is no longer providing quarterly or annual guidance.

The earnings press release and accompanying financial data tables will be accessible on the Investor Relations section of the company’s website at PTC Investor Relations.

About

PTC (NASDAQ: PTC) is a global software company that enables manufacturers and product companies to digitally transform how they design, manufacture, and service the physical products the world relies on. Headquartered in Boston, Massachusetts, PTC employs over 7,000 people and supports more than 30,000 customers globally. For more information, please visit www.ptc.com.

Investors

Michael Maguire
mmaguire@ptc.com
investor@ptc.com

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SOURCE PTC Inc.

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