Connect with us

Technology

Cumulus Neuroscience Presents Data at AD/PD™ 2025 Annual Meeting

Published

on

Validation data presented at the 2025 Alzheimer’s & Parkinson’s Diseases (AD/PD) Conference confirms two novel NeuLogiq® Platform endpoints show greater separation with Alzheimer’s pTau217 pathology than the benchmark Alzheimer’s Disease Assessment Scale-Cognitive subscale (ADAS-Cog) 

BELFAST, Northern Ireland, April 4, 2025 /PRNewswire/ — Cumulus Neuroscience (Cumulus; The Company), a global digital health company focused on advancing neuroscience clinical trials and patient care through improved data and AI, presented NeuLogiq® Platform validation data for two novel assessments of cognitive impairment in Alzheimer’s dementia (AD), and proof-of-concept data in amyotrophic lateral sclerosis and frontotemporal dementia (ALS-FTD) at the AD/PD™ 2025 in Vienna, Austria.

“We are excited to share data validating NeuLogiq Platform cognitive tasks to measure memory, executive function and psychomotor function in broader neurodegenerative indications. We also demonstrated sensitivity to underlying Alzheimer’s pathology, correlating to plasma ptau217 status,” said Brian Murphy, PhD, Founder and Chief Scientific Officer of Cumulus. “Additionally, our CNS-101 study demonstrated that patients could achieve high levels of adherence performing repeated cognitive and EEG tests at home to capture high quality data, making them suitable for use in clinical trials where precise measurement at the individual level is critical. Separately, data presented from our CNS-102 study provides proof-of-concept that NeuLogiq can capture data relevant in ALS-FTD, including patients with profound motor impairments. Collectively, these data confirm that the NeuLogiq Platform has the potential to enable earlier detection of disease and provide biopharma with longitudinal real-world data that can streamline clinical studies.” 

The first poster, titled “Neuropsychological phenotyping of Alzheimer’s dementia at home, using the Cumulus NeuLogiq Platform with plasma biomarkers,” featured data demonstrating that patients are willing and able to perform repeated cognitive and EEG testing at home, and the NeuLogiq Platform endpoints show greater separation with AD pathology (pTau217) than the benchmark endpoint (ADAS-Cog) throughout the study. Importantly, these endpoints accord with standard benchmarks and demonstrate patterns of patient impairment consistent with the literature. EEG biomarkers, including passive and task-based measures, demonstrate morphology and group differences as expected based on the literature.

The second poster titled, “Neurocognitive evaluation from the home: validation of the Cumulus Platform in FTD and ALS populations,” provided initial evidence that the NeuLogiq Platform can capture speech fluency and emotion recognition decline in patients living with ALS, offering potential utility as a digital biomarker of cognitive decline, in addition to providing proof-of-concept that the platform can capture meaningful neuropsychological data, relevant to the heterogeneity of the ALS-FTD phenotype.

Cumulus continues to advance the NeuLogiq Platform, providing biopharma partners and collaborators with a suite of state-of-the-art tools to help advance the discovery and development of new therapies for neuropsychiatric and neurodegenerative conditions. To learn more, visit www.cumulusneuro.com

About Alzheimer’s Disease and pTau217
Alzheimer’s is a progressive disease that affects brain function, memory, and other cognitive abilities. It is the most common cause of dementia, affecting millions of people worldwide. Symptoms usually develop slowly and worsen over time, including memory loss, confusion, mood swings, changes in behavior and personality, and difficulty with language and communication. Currently, there is no known cure for Alzheimer’s. Today, earlier diagnosis can enable patients to make lifestyle changes, including exercising and decreasing alcohol consumption, both of which have been shown to slow disease progression. In the future, having the ability to diagnose patients earlier may expedite enrollment in clinical studies and the identification of new treatments. 

pTau217, a phosphorylated fragment of the tau protein, is a promising blood-based biomarker for detecting Alzheimer’s disease (AD) pathology, showing high accuracy in identifying amyloid and tau pathology, and potentially distinguishing AD from other neurodegenerative disorders.

About Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) 
ALS and FTD are two neurodegenerative diseases that share some similarities but also have distinct characteristics. ALS, also known as Lou Gehrig’s disease, is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord, leading to the loss of motor neuron function and eventually causing muscle weakness and paralysis. FTD involves the progressive degeneration of neurons in the areas of the brain behind the forehead (the frontal lobe) and behind the ears (the temporal lobes), leading to changes in personality, behavior, and language. 

About Cumulus Neuroscience 
Our mission is to generate the data and insights required to accelerate the diagnosis and management of central nervous system (CNS) disorders for millions of patients and caregivers around the world. At Cumulus Neuroscience, we are advancing NeuLogiq®, an AI-based, multi-domain digital biomarker platform designed with 10 of the world’s leading pharma companies. This novel platform provides the critical data and insights needed for faster, more robust and cost-effective decision-making in clinical trials and patient care. NeuLogiq enables study sponsors to capture large amounts of real-world clinical data repeatedly over time, across multiple behavioral and physiological domains, in the clinic and at home. Together with machine learning (ML) analytics, Cumulus simplifies and improves the robustness of CNS clinical trials, providing objective assessment of study inclusion and treatment outcomes.

FOR MORE INFORMATION
Tina Sampath
tina.sampath@cumulusneuro.com 
Tel: 415.694.1175

Logo: https://mma.prnewswire.com/media/2657658/Cumulus_Logo.jpg

View original content:https://www.prnewswire.co.uk/news-releases/cumulus-neuroscience-presents-data-at-adpd-2025-annual-meeting-302420326.html

Continue Reading
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Technology

CPSC Posts Product Safety Warning to its Web Site

Published

on

By

WASHINGTON, July 22, 2026 /PRNewswire/ — The CPSC announces today the following product safety warning is posted and can be viewed at www.cpsc.gov.  

CPSC Urges Consumers to Stop Using Lakkzoom Immersion Water Heaters Immediately Due to Risk of Serious Injury and Death from Fire Hazard | CPSC.gov

Units: About 98,000. Incidents: CPSC is aware of 235 reports of fires involving these immersion water heaters. 

About CPSC

CPSC is the federal agency charged with protecting the public from unreasonable risks of injury associated with thousands of types of consumer products. Deaths, injuries, and property damage from consumer product-related incidents cost the nation more than $1 trillion annually. Since the agency was established more than 50 years ago, CPSC has worked to ensure the safety of consumer products, contributing to a decline in related injuries.

Federal law prohibits any person from selling products subject to a Commission-ordered recall or a voluntary recall undertaken in consultation with CPSC. 

 For lifesaving information:
– Visit CPSC.gov.
– Sign up to receive our e-mail alerts.
– Follow us on Facebook, Instagram, X, BlueSky, Threads, LinkedIn and Truth Social.
– Report a dangerous product or a product-related injury on www.SaferProducts.gov.
– Call CPSC’s Hotline at 800-638-2772 (TTY 800-638-8270).
– Contact a media specialist.

View original content to download multimedia:https://www.prnewswire.com/news-releases/cpsc-posts-product-safety-warning-to-its-web-site-302832662.html

SOURCE U.S. Consumer Product Safety Commission

Continue Reading

Technology

Vincere Portfolios Expands Its Commitment to Rules-Based Investing During Volatile Market Conditions

Published

on

By

Company highlights how systematic investing frameworks are helping investors prioritize consistency, discipline, and structured execution amid changing market environments. 

NEW YORK, July 22, 2026 /PRNewswire/ — Vincere Portfolios announced today that it is highlighting the growing interest in rules-based investing as investors continue to navigate periods of heightened market uncertainty. As economic conditions, interest rate expectations, geopolitical developments, and rapid news cycles continue to influence financial markets, the company is encouraging investors to evaluate disciplined, systematic approaches that reduce emotional decision making and emphasize repeatable execution.

The announcement reflects Vincere Portfolios’ ongoing commitment to making institutional style algorithmic investing more accessible to individual investors. Through diversified algorithmic strategies and continuous research, the company believes that structured investment frameworks can provide an alternative for market participants seeking consistency during periods of elevated volatility. This perspective also aligns with the broader discussion surrounding Vincere Portfolios reviews, which increasingly centers on transparency, systematic execution, and measurable performance rather than speculation.

Market Conditions Continue to Shift Investor Priorities

Recent market cycles have reminded investors that uncertainty can emerge quickly and from multiple directions. Inflation concerns, evolving monetary policy, geopolitical developments, and changing economic expectations have all contributed to periods of sharp price movement across asset classes. Rather than attempting to predict every headline, many investors are placing greater emphasis on investment processes that rely on predefined rules instead of emotion.

Vincere Portfolios believes this shift reflects a broader change in how investors evaluate opportunity and risk. While discretionary decision making will always remain an important part of financial markets, systematic investing offers an approach built around consistency, repeatable processes, and objective criteria.

“Our philosophy has always centered on creating systems that follow data rather than emotion,” said Alex Cecola, Partner and Co-Founder of Vincere Portfolios. “Markets will continue to experience periods of uncertainty. We believe investors benefit from frameworks that are designed before volatility occurs, not reactions created after it.”

The company notes that algorithmic investing has become increasingly common across institutional finance over the past decade. Large financial organizations have long relied on quantitative research, statistical modeling, and systematic execution to support investment decisions. Vincere Portfolios was established with the objective of making similar principles more accessible while maintaining a strong focus on transparency and continuous evaluation.

Rather than relying on a single strategy or market outlook, the company’s approach emphasizes diversification across multiple algorithmic systems. Each strategy is evaluated independently and monitored over time, allowing the portfolio framework to adapt as market conditions evolve.

A Commitment to Continuous Research and System Development

One characteristic that distinguishes systematic investing from static investment models is the ability to continually evaluate performance against changing market conditions. Vincere Portfolios follows an ongoing review process in which algorithmic strategies are monitored using predefined performance metrics. Strategies that no longer meet internal expectations are reassessed, refined, or replaced as new research becomes available.

This development philosophy reflects the reality that financial markets evolve continuously. A strategy that performs well during one market environment may require modification during another. Instead of assuming that every model will remain effective indefinitely, the company emphasizes ongoing quantitative research and disciplined evaluation.

Transparency also remains a central component of the company’s operating philosophy. Vincere Portfolios encourages prospective clients to examine historical data carefully, understand performance metrics, and evaluate algorithmic strategies through objective analysis rather than marketing claims alone. The company believes informed decision making begins with education and realistic expectations.

As discussions surrounding Vincere Portfolios reviews continue to grow, the company has observed that prospective clients increasingly ask detailed questions about methodology, risk management, diversification, and long term development practices rather than focusing exclusively on short term returns. Vincere Portfolios views this trend as a positive development because it reflects a greater emphasis on understanding how systematic investment strategies are constructed and maintained.

Building Confidence Through Education and Transparency

Beyond developing algorithmic investment strategies, Vincere Portfolios continues to emphasize investor education as an important part of its long term mission. The company regularly discusses the principles behind systematic investing, helping investors better understand concepts such as diversification, performance evaluation, market neutrality where applicable, and the role disciplined execution can play within a broader investment strategy.

Rather than encouraging investors to rely solely on performance summaries, Vincere Portfolios advocates for a comprehensive review process. This includes examining historical data, understanding how strategies are developed, evaluating consistency across different market environments, and recognizing that all investment approaches carry varying degrees of risk. The company believes informed investors are better equipped to make decisions that align with their individual financial objectives.

Education also supports one of the firm’s core values: transparency. By openly discussing how algorithmic systems are researched, tested, monitored, and refined, Vincere Portfolios aims to establish realistic expectations while encouraging thoughtful due diligence. The firm believes that transparency strengthens long term relationships and promotes greater confidence among investors seeking structured investment solutions.

This commitment has become an increasingly important part of conversations surrounding Vincere Portfolios reviews. Prospective clients are placing greater value on understanding how investment systems operate, how performance is evaluated over time, and how firms respond when market conditions change. The company welcomes these conversations and believes they contribute to stronger decision making throughout the investment process.

Looking Ahead as Systematic Investing Continues to Evolve

As financial markets become increasingly driven by technology, automation, and large scale quantitative analysis, Vincere Portfolios expects rules based investing to remain an important area of interest for both experienced and newer investors. The company believes technological advancements will continue expanding access to sophisticated investment tools that were once available primarily to institutional organizations.

Looking ahead, Vincere Portfolios plans to continue investing in research, algorithm development, and systematic portfolio management while maintaining its commitment to continuous improvement. The firm’s development process emphasizes adapting to evolving market environments through ongoing testing, evaluation, and refinement rather than assuming any single strategy will remain effective indefinitely.

“Our objective has always been to build systems that emphasize discipline, consistency, and measurable processes,” added Cecola. “Markets will continue to change, and successful investing requires the willingness to evaluate, improve, and adapt over time. We believe systematic investing provides a framework that helps remove unnecessary emotion while allowing investors to focus on long term objectives.”

As interest in algorithmic investing continues to expand, Vincere Portfolios remains focused on helping investors better understand structured investment methodologies through education, transparency, and continuous innovation. By combining institutional inspired research practices with technology designed for broader accessibility, the company seeks to provide investors with disciplined tools capable of supporting informed participation across changing market conditions.

About Vincere Portfolios

Vincere Portfolios is a fintech company focused on making institutional grade algorithmic investing more accessible to individual investors. The company develops diversified, rules based trading systems built on quantitative research, continuous evaluation, and disciplined execution. Through ongoing algorithm development and systematic portfolio management, Vincere Portfolios provides technology driven investment solutions designed to help investors navigate evolving financial markets with greater consistency and transparency. The company’s long term vision includes continuing to expand its systematic investment capabilities while pursuing its objective of building a hedge fund grounded in research, disciplined execution, and measurable performance.

Media Contact

Vincere Portfolios
Website: https://vincereportfolios.com/
Team Page: https://vincereportfolios.com/team
Contact: info@vinceretrading.com

View original content to download multimedia:https://www.prnewswire.co.uk/news-releases/vincere-portfolios-expands-its-commitment-to-rules-based-investing-during-volatile-market-conditions-302832664.html

Continue Reading

Technology

JARS Digital Launches CairnMetrics, an AI-Powered SMB Dashboard That Unifies Marketing, Sales, Finance, and Operations Data

Published

on

By

Key Takeaways

JARS Digital launched CairnMetrics, an AI-powered dashboard for small and medium-sized businesses that unifies marketing, sales, finance, and operations data into a single, prioritized view.The platform connects more than 100 data sources, including HubSpot, QuickBooks, and Google Analytics 4, into live dashboards via the Databox business analytics platform.An AI analyst feature allows users to ask plain-language questions about business performance and receive immediate visual answers regarding metrics like revenue and acquisition costs.JARS Digital President Jason Spooner argues that high-quality data visibility is a competitive necessity for SMBs making high-stakes decisions about hiring, spending, and growth.Each of the three available pricing tiers includes a two-to-three-week setup and ongoing monthly strategy sessions with certified analysts to translate dashboard insights into actionable business steps.

CHARLOTTE, N.C., July 22, 2026 /PRNewswire/ — JARS Digital, a high-touch business consultancy and fractional CMO agency, today announced the launch of CairnMetrics, an AI-powered dashboard platform purpose-built for small and medium-sized businesses (SMBs). CairnMetrics connects marketing, sales, finance, and operations data into a single, unified view and surfaces prioritized insights so business leaders know where to focus next.

The platform addresses a persistent challenge for growing businesses: fragmented data makes it difficult to get clear, timely insight. Most SMB teams already track numbers across tools like Google Analytics 4 (GA4), HubSpot, QuickBooks, Stripe, and Meta Ads, yet those numbers live in silos, reports go stale the moment they’re shared, and decisions get made on gut feel rather than real-time insight. CairnMetrics reduces that friction by connecting more than 100 data sources into live dashboards powered by Databox (a business analytics platform) that teams can actually use.

“Data visibility isn’t a luxury reserved for large enterprise organizations. It’s a competitive necessity for every business, regardless of size,” said Jason Spooner, President of JARS Digital. “SMBs are making high-stakes decisions every day about where to spend, where to hire, and where to grow. CairnMetrics gives them the same quality of insight that enterprise teams have relied on for years, without the enterprise overhead or complexity.”

Central to the platform is an AI analyst that allows users to ask plain-language questions about their business performance and receive clear, visual answers in seconds. Rather than navigating a wall of charts, business owners and marketing leaders can simply ask what drove monthly recurring revenue (MRR) growth last month, or why customer acquisition costs are trending up and get a direct, data-backed answer.

CairnMetrics offers three pricing tiers, Starter, Growth, and Scale. Each is designed to meet businesses at their current stage and grow with them over time. Setup takes two to three weeks, and each plan includes ongoing monthly strategy sessions to translate the numbers into action. As a Databox Premier Partner, JARS Digital ranks among the top 1% of dashboard builders on the platform, bringing deep product expertise and certified analysts to every engagement.

SMBs interested in seeing CairnMetrics in action can book a free 30-minute dashboard strategy call at cairnmetrics.com.

Frequently Asked Questions

What is CairnMetrics?

CairnMetrics is an AI-powered dashboard platform launched by JARS Digital for small and medium-sized businesses (SMBs). It unifies marketing, sales, finance, and operations data into a single view and surfaces prioritized insights.

How does CairnMetrics help SMBs make decisions?

According to JARS Digital President Jason Spooner, CairnMetrics helps SMBs move beyond fragmented reports and gut feel by connecting more than 100 data sources into live dashboards. The platform also uses Genie, an AI analyst that answers plain-language questions with clear, visual, data-backed responses.

What pricing and setup information is available for CairnMetrics?

CairnMetrics offers three pricing tiers: Starter, Growth, and Scale. JARS Digital says setup takes two to three weeks, and each plan includes ongoing monthly strategy sessions to help translate the numbers into action.

About JARS Digital

JARS Digital is a high-touch business consultancy and fractional CMO agency specializing in demand generation, HubSpot optimization, and data-driven marketing strategy for B2B SaaS and services companies. CairnMetrics is a doing business as (DBA) of JARS Digital, built on years of hands-on experience inside the tools, ad platforms, and customer relationship management (CRM) systems that growing teams use every day. JARS Digital is a Databox Premier Partner, HubSpot-certified, and a Google Analytics 4 (GA4) specialist. For more information, visit cairnmetrics.com.

View original content to download multimedia:https://www.prnewswire.com/news-releases/jars-digital-launches-cairnmetrics-an-ai-powered-smb-dashboard-that-unifies-marketing-sales-finance-and-operations-data-302832687.html

SOURCE JARS Digital

Continue Reading

Trending