Connect with us

Technology

PredxBio Launches Enhanced SpaceIQ™ Platform with Multiomic Spatial Capabilities Ahead of AACR 2025

Published

on

PredxBio today announced the official launch of enhanced SpaceIQ™ platform to integrate brightfield, spatial proteomics and transcriptomics datasets to deliver a unified, high-resolution view of the tumor microenvironment—unlocking new insights into cellular interactions, immune architecture, and mechanisms of therapeutic response and resistance. This milestone launch, timed ahead of the American Association for Cancer Research (AACR) Annual Meeting 2025, will be highlighted by two scientific poster presentations and a spotlight symposium at the conference. The new capabilities of SpaceIQ™ are poised to accelerate insights in cancer biology, improve patient stratification, and drive advances in precision immuno-oncology.

PITTSBURGH, April 25, 2025 /PRNewswire-PRWeb/ — PredxBio today announced the official launch of enhanced SpaceIQ™ platform to integrate brightfield, spatial proteomics and transcriptomics datasets to deliver a unified, high-resolution view of the tumor microenvironment—unlocking new insights into cellular interactions, immune architecture, and mechanisms of therapeutic response and resistance. This milestone launch, timed ahead of the American Association for Cancer Research (AACR) Annual Meeting 2025, will be highlighted by two scientific poster presentations and a spotlight symposium at the conference. The new capabilities of SpaceIQ™ are poised to accelerate insights in cancer biology, improve patient stratification, and drive advances in precision immuno-oncology.

By integrating multiomic spatial data with SpaceIQ™, we are advancing the frontier of precision oncology – translating these insights into actionable solutions for patient care.

SpaceIQ™ is an explainable AI-driven spatial multiomics platform that provides a rigorous framework to interrogate the tumor microenvironment. With its latest upgrade, SpaceIQ™ can now ingest and co-analyze brightfield, spatial proteomics and transcriptomics datasets from tumor samples. Researchers are able to map gene expression profiles onto tissue architecture and identify complex cellular neighborhoods (or “microdomains”) that drive tumor progression and immune evasion. By leveraging probabilistic modeling and unbiased cell typing, SpaceIQ™ uncovers transition cell states, cell–cell interactions, and mechanistic pathway networks within the tumor – yielding a deeper understanding of tumor heterogeneity and therapy resistance.

“PredxBio’s unique capabilities in unbiased cell typing and explainable AI allow us to decode the mechanistic complexities of the tumor microenvironment,” said S. Chakra Chennubhotla, PhD, Chief of AI at PredxBio. “By integrating multiomic spatial data with SpaceIQ™, we are advancing the frontier of precision oncology – translating these insights into actionable solutions for patient care.”

At AACR 2025 in Chicago, PredxBio and its collaborators will present two new studies showcasing SpaceIQ™’s impact:

Poster 1 (Abstract #2485): “A Bayesian Framework for Unraveling Disease Biology from Spatially Resolved Single-Cell Omics Datasets.” Co-authored in collaboration with Arutha Kulasinghe, PhD, Director of the Queensland Spatial Biology Centre, this poster introduces a novel Bayesian approach for analyzing high-dimensional spatial single-cell data. Presentation Time: April 28, 2025, 9:00 AM–12:00 PM CT (Poster Section 47, Board #6). The study demonstrates how combining unbiased computational methods with biological priors in SpaceIQ™ can reveal emergent cell types and microdomains, offering new insights into disease mechanisms.Poster 2 (Abstract #5317): “Multimodal Spatial Analysis of Colon Cancer Tissue Reveals Emergence of an Immunosuppressive Tumor Maintenance Mechanism.” Co-authored by Gaurav N. Joshi, PhD, and colleagues from Nikon BioImaging Lab in Boston, this research applies SpaceIQ™ to a colon cancer sample by integrating mIF and spatial transcriptomics. Presentation Time: April 29, 2025, 2:00 PM–5:00 PM CT (Poster Section 8, Board #23). This study uncovers how tumor and immune cells are spatially organized to create an immunosuppressive microenvironment that supports tumor maintenance.

“Using SpaceIQ’s multiomic analysis, we discovered an immunosuppressive mechanism in colon cancer that would have been difficult to detect with single-modality data,” noted Gaurav N. Joshi, PhD, lead author of the colon cancer study. “By combining brightfield, spatial proteomics and transcriptomics datasets, we can see how different immune cells and signals interact within the tumor microenvironment. This level of insight is invaluable for precision immuno-oncology, as it points to biomarkers and therapeutic targets that can inform more effective, personalized treatments.”

Spotlight Symposium at AACR 2025

The launch of SpaceIQ™ will also be highlighted during a Spotlight Theater Symposium titled:

“Harnessing Spatial Multiomic Biomarkers: Ushering in a New Era of Precision Oncology”

Date: Sunday, April 27, 2025Time: 3:30 PM4:30 PM CTLocation: Spotlight Theater D, McCormick Place, Chicago

The session will begin with a joint presentation by B. Dusty Majumdar, PhD, S. Chakra Chennubhotla, PhD, and A/Prof. Arutha Kulasinghe, followed by a panel discussion featuring spatial biology experts from academia and industry. Attendees will hear how SpaceIQ™ can be applied to decode tumor complexity and guide biomarker discovery, patient stratification, and companion diagnostic development.

Visit PredxBio at AACR 2025

Exhibit Booth: #3252Conference Dates: April 26–30, 2025Venue: McCormick Place, Chicago, IL

Attendees are invited to stop by the booth for hands-on demonstrations and to learn how SpaceIQ™ is enabling faster, more informed decisions in drug development, biomarker discovery, and patient stratification.

About PredxBio

PredxBio is a spatial analytics company headquartered in Pittsburgh, PA, powering next-generation cancer therapeutics with its AI-driven spatial biomarkers. PredxBio’s proprietary approaches delve into the mechanism of action of drugs and predict patient outcomes with over 90% accuracy. By transforming multiplexed biopsy images and multi-modal spatial data into actionable insights – and revealing the network biology of cancer – PredxBio is setting new standards for biomarker discovery and clinical research. In partnership with leading pharmaceutical companies and research institutions, PredxBio is accelerating drug discovery and advancing personalized medicine to impact cancer patients globally. For more information, visit www.predxbio.com

Media Contact

A. Burak Tosun, PredxBio, 1 4122123115, info@predxbio.com, www.predxbio.com

LinkedIn

View original content:https://www.prweb.com/releases/predxbio-launches-enhanced-spaceiq-platform-with-multiomic-spatial-capabilities-ahead-of-aacr-2025-302438004.html

SOURCE PredxBio

Continue Reading
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Technology

Lianlian DigiTech Returns to Money20/20 Asia to Expand Partnerships, Share Industry Trends, and Explore AI-Enabled Global Financial Infrastructure

Published

on

By

BANGKOK, April 26, 2026 /PRNewswire/ — Lianlian DigiTech, a leading global provider of digital payment services, was once again invited to participate in Money20/20 Asia, one of the world’s most influential fintech gatherings, held in Bangkok, Thailand from April 21 to 23. At the event, the company presented its latest developments in cross-border payment infrastructure, technology innovation, and ecosystem collaboration, offering a comprehensive view of its work enhancing global cross-border payment capabilities.

During the conference, Lianlian DigiTech announced a strategic partnership with UK-based fintech company USI Money to further strengthen its global cross-border payment network, delivering more efficient and reliable fund flows for merchants worldwide. Shen Enguang, Co-President of Lianlian DigiTech; Mark Ma, Head of Global Banking Partnership at LianLian Global; and Bryan Jiang, General Manager Hong Kong of LianLian Global, attended the event and engaged with representatives from international financial institutions. They shared perspectives on fintech trends and global payment innovation, offering industry insight into the continued evolution of a more integrated and interoperable cross-border payments ecosystem.

Building a Borderless Payment Network with Global Partners Including USI Money

At the event, Lianlian DigiTech formalized a strategic collaboration with London-headquartered USI Money to further develop its global payment infrastructure.

The partnership will focus on cross-border remittance and foreign exchange services, combining both companies’ technological capabilities and resources to deliver a one-stop payment and collection solution for global businesses. The offering is built to be efficient, secure, and cost-effective, improving overall fund flow efficiency and streamlining foreign exchange execution.

Syed Bukhari, Group Chief Business and Operating Officer at USI Money, said: “Our partnership with Lianlian will strengthen our remittance capabilities, creating greater value for our customers through broader network coverage and improved transaction performance.”

Bryan Jiang, General Manager Hong Kong of LianLian Global, said: “By leveraging the complementary strengths of our ecosystem partners in technology and compliance, Lianlian will continue to scale its global payment network and improve transaction efficiency. We remain committed to enhancing financial connectivity across global financial markets and delivering more efficient and reliable cross-border payment solutions for our customers.”

Founded in 2009 and listed on the Main Board of the Hong Kong Stock Exchange in 2024 (2598.HK), Lianlian DigiTech is a China-based, globally focused digital payment company with increasingly integrated AI capabilities across its platform. Guided by its mission of “Connecting the world, Empowering global commerce,” the company focuses on developing a trusted and scalable financial infrastructure. As of the end of 2025, Lianlian DigiTech has built a cross-border payment network covering more than 100 countries and regions, serving over 10.4 million customers worldwide.

USI Money is a foreign exchange and international remittance service provider offering tailored cross-border financial solutions for businesses and individuals. With competitive real-time exchange rates and efficient execution as its core strengths, the company delivers fast, secure, and reliable global fund transfers.

In addition, Lianlian DigiTech co-hosted a networking session with Unlimit during the event, providing a forum for industry dialogue. The session brought together a broad group of fintech partners to explore collaborative models and help foster a more connected ecosystem.

Industry Roundtables: Unlocking Layered Collaboration in AI-Driven Cross-Border Payments and Advancing Financial Inclusion in Emerging Markets

At the same time, Mark Ma and Bryan Jiang were invited to the themed roundtable discussions, where they shared insights drawn from industry practice and outlined new approaches to aligning fintech innovation with the global financial system.

At the roundtable on “Fintech and Banks,” Mark Ma noted that the global payment system is rapidly shifting from isolated capabilities to a layered, collaborative model. Banks continue to serve as the foundational infrastructure, responsible for clearing networks and liquidity management. Fintech firms like Lianlian, meanwhile, build on top of this foundation to deliver application-layer services for businesses, transforming complex cross-border payment channels into more accessible solutions that support a wider range of practical business scenarios. He also emphasized fintech’s growing role in compliance and value creation. By embedding risk controls and verification processes into technology workflows, fintech companies can act as compliance intermediaries, improving efficiency while filtering risk and enabling banks to operate more effectively at scale. Meanwhile, insights derived from transaction data and business flows allow for more precise evaluation of small and medium-sized businesses, shifting capital allocation from experience-based decisions to data-driven approaches and improving access to financial services.

At the roundtable titled “Different Worlds, Shared Challenges: Bridging Emerging Markets,” Bryan Jiang pointed out that the core of financial inclusion is shifting from scale of coverage to practical usability in everyday financial activity. The ability to serve underserved segments such as small and micro merchants and overseas workers in a sustained and reliable manner ultimately depends on continuous improvements in product design and operational capabilities. Using emerging markets as an example, Jiang explained that small and medium-sized businesses in these regions often face challenges such as difficult account setup, complex cross-border collections, high foreign exchange costs, and multi-layered tax requirements. Many existing solutions still follow traditional business-focused models, resulting in cumbersome KYB processes and lengthy review cycles that are misaligned with the asset-light, high-frequency, fast-turnover nature of these businesses. In response, Lianlian has lowered barriers to fund flows by offering local collection accounts, optimizing foreign exchange mechanisms, and improving settlement efficiency. The company has also restructured account architecture, streamlined review processes, and enhanced fund visibility, creating a more seamless and intuitive user experience that better aligns financial services with its clients’ business operations and day-to-day activities.

As digital technologies increasingly integrate with the real economy, innovations in AI and blockchain are reshaping the foundations of global financial services. Lianlian DigiTech has long invested in AI capabilities, global compliance, and the growth of its international service network. Its broad licensing coverage, regulatory track record, localized service capabilities, and technical reliability have earned the trust of regulators, customers, and partners worldwide.

Looking ahead, Lianlian DigiTech will continue to build on its cross-border expertise and compliance experience to further develop its AI capabilities and deepen collaboration with global partners. The company aims to extend its role beyond payment network services into more integrated financial infrastructure solutions. Lianlian DigiTech remains committed to serving as a trusted platform for global financial transactions in an increasingly digital environment, enabling businesses and individuals worldwide to access faster, more efficient, and more seamless cross-border financial services.

View original content:https://www.prnewswire.com/apac/news-releases/lianlian-digitech-returns-to-money2020-asia-to-expand-partnerships-share-industry-trends-and-explore-ai-enabled-global-financial-infrastructure-302753667.html

SOURCE LianLian Global

Continue Reading

Technology

The Building & Furniture Category Highlights Sustainable and Human‑Centric Design at the 139th Canton Fair

Published

on

By

GUANGZHOU, China, April 26, 2026 /PRNewswire/ — Phase 2 of the 139th Canton Fair has seen the Building & Furniture category emphasize green Infrastructure and human-centric design.

A major highlight of the building and decorative materials section is the introduction of photovoltaic marble-textured cladding. This innovative surfacing material bridges the gap between high-end aesthetics and renewable energy. Unlike traditional solar panels that rely on glass, this non-opaque cladding uses precise microscopic structures to guide light to internal PV cells.

This technology offers 60% higher efficiency than traditional transparent solar systems while reducing carbon emissions by over 50%. Its ability to reproduce stone, wood, or brick‑like 3D textures allows architects to integrate power generation into a wide range of building styles without the industrial appearance of traditional solar panels.

Indoor environments are also becoming smarter and safer. Manufacturers are showcasing high-efficiency antibacterial surfacing, utilizing visible light catalysis to provide 24-hour protection against mold and bacteria. These advanced decorative papers and panels are becoming the new standard for high-end interior decoration, prioritizing long-term hygiene in residential and commercial spaces.

The sanitary ware sector is increasingly focused on the aging global population and those with limited mobility. A standout innovation is the electric lift-and-rotate shower chair. Designed for the dry-wet separation bathroom layout, it allows users to sit in a dry area and be safely rotated and lifted into the shower via remote control. This waterproof, low-voltage system provides dignity and independence for the elderly while reducing the physical strain on caregivers.

Hygiene and ease of maintenance have also seen a breakthrough with wall-mounted toilets. By moving the lid connection to the tank wall and adopting a mortise‑and‑tenon structure, the design eliminates the hard‑to‑clean areas where bacteria typically accumulate. Many of these units also incorporate ergonomic grab bars directly into the frame, blending safety with a minimalist aesthetic.

In the sports and leisure industry, the shift toward sustainability is seen in non-infill synthetic turf. This next-generation football grass eliminates the need for rubber granules or sand, providing a natural touch and superior shock absorption while significantly reducing maintenance costs and microplastic pollution.

All these innovations demonstrate how the Building & Furniture sector is advancing toward greener materials, smarter functionality, and more human‑centered design, setting new benchmarks for the future of living spaces.

For pre-registration, please click: https://buyer.cantonfair.org.cn/register/buyer/email?source_type=16

Photo – https://mma.prnewswire.com/media/2965701/Image1.jpg

View original content:https://www.prnewswire.co.uk/news-releases/the-building–furniture-category-highlights-sustainable-and-humancentric-design-at-the-139th-canton-fair-302753654.html

Continue Reading

Technology

Nexteer’s Global First Steer-by-Wire Goes into Production

Published

on

By

BEIJING, April 26, 2026 /PRNewswire/ — Nexteer Automotive helped a leading Chinese new energy vehicle (NEV) manufacturer bring the world’s first production passenger vehicle with a full drive‑by‑wire chassis to market. The vehicle features Nexteer’s steer‑by‑wire (SbW) system as a key enabler.

The SbW featured in this vehicle marks Nexteer’s first SbW system in mass production, representing a major step forward for the technology — moving from development and validation to full-scale production. Certified in late 2025, this system achieved the world’s first ASIL D functional safety approval from DAkkS (German Accreditation Body) through close collaboration with the OEM. This certification reflects global top-tier performance in fault diagnosis, redundancy, and safety monitoring. Key features include:

Multi-layered redundancy design: Dual controllers, dual power supplies, multiple communication links, and dual actuation paths — achieving redundancy at system, hardware, and software levels. This ensures that in the event of a single fault, the backup path takes over within milliseconds with no loss of steering function.Full‑scenario functional safety mechanism: Multi‑level monitoring and fault handling strategies covering sensors, controllers, actuators, and communication links.Variable steering ratio: Automatically adjusts steering angle and effort based on vehicle speed and driving mode, balancing agility and comfort.Intuitive road‑feel simulation technology: Software‑defined steering feedback delivers a more responsive and precise driving experience, adaptable to a wide range of driving scenarios.Open interface for autonomous driving: As a key actuation layer for ADAS and autonomous driving systems, it provides real‑time, precise control capabilities, supporting the development of intelligent transportation systems.

Steer-by-Wire: Electronic Signals Replace Mechanical Links, Flexible Configurations for Diverse Needs

By decoupling the mechanical link between the hand wheel and the road wheels, steer-by-wire replaces conventional mechanical connections with electronic signals and actuators — and is quickly becoming a foundational technology for next-generation intelligent chassis and autonomous driving platforms. As a motion control technology company with 120 years of engineering heritage, Nexteer offers a flexible, off-the-shelf portfolio of steering feel simulators and road wheel actuators. This modular approach allows us to meet the diverse needs of different vehicle models and driving scenarios efficiently and cost-effectively.

From Steering to Braking: Expanding Full-Stack Motion Control Capabilities

Building on its deep expertise in steering systems, Nexteer has expanded into braking with its Brake-by-Wire solution, the Electro-Mechanical Brake (EMB). EMB has completed full development and rigorous validation and is ready for mass production. Together with SbW, Brake-by-Wire (EMB), Rear-Wheel Steering, and the MotionIQ™ Software Suite make up Nexteer’s broader Motion-by-Wire™ portfolio.

With Nexteer, OEMs get more than steer-by-wire and brake-by-wire components: they get a complete, proven, production-ready and cost-effective drive-by-wire chassis motion control solution that’s shaping the future of the software-defined chassis and enabling faster development, lower costs and safter, smarter and more exciting driving experiences.

During Auto China 2026, we cordially invite you to visit Nexteer at Booth W1B03, Hall W1, China International Exhibition Center (Shunyi) in Beijing, to experience firsthand the breakthrough innovations of steer-by-wire and Motion-by-Wire™ technologies.

ABOUT NEXTEER AUTOMOTIVE

Nexteer Automotive (HK 1316) is a global leading motion control technology company accelerating mobility to be safe, green and exciting. Our innovative portfolio supports Motion-by-Wire™ chassis control, including electric and hydraulic power steering systems, steer-by-wire and rear-wheel steering systems, steering columns and intermediate shafts, driveline systems, software solutions and brake-by-wire. Celebrating 120 years of automotive innovation in 2026, Nexteer builds on a strong legacy of engineering excellence while continuing to shape the future of mobility. The company solves motion control challenges across all megatrends – including electrification, software/connectivity, ADAS/automated driving and shared mobility – for global and domestic OEMs around the world including BMW, Ford, GM, RNM, Stellantis, Toyota and VW, as well as automakers in India and China including BYD, Xiaomi, ChangAn, Li Auto, Chery, Great Wall, Geely, Xpeng and others. www.nexteer.com  

Links to Nexteer Media Center

Logo – https://mma.prnewswire.com/media/2368187/5937537/nexteer_Logo.jpg

View original content:https://www.prnewswire.com/in/news-releases/nexteers-global-first-steer-by-wire-goes-into-production-302753641.html

Continue Reading

Trending