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Hartwig Medical Foundation and Ultima Genomics Expand Collaboration to Advance Whole-Genome Sequencing in Oncology Care

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Hartwig to adopt Ultima Genomics’ UG200 sequencing system to accelerate implementation of whole-genome-based clinical genomics workflows on Solaris 2.0 technology

Hartwig and Ultima to continue implementation and validation of ppmSeq, the only decentralizable whole-genome solution commercially available today for monitoring of minimal residual disease (MRD) with low single-digit part-per-million sensitivity

AMSTERDAM and FREMONT, Calif., June 12, 2026 /PRNewswire/ — Hartwig Medical Foundation and Ultima Genomics today announced an expansion of their strategic collaboration, marked by Hartwig’s adoption of the new Ultima UG200™, Ultima’s 2nd generation sequencing system. The agreement builds on the organization’s existing work with Ultima’s technology and is designed to accelerate Hartwig’s mission to make whole-genome sequencing (WGS) more accessible, scalable, and clinically actionable for oncology patients.

Hartwig has been a pioneer in applying WGS for cancer diagnostics. Through OncoAct Whole Genome Sequencing (OncoAct WGS), Hartwig’s comprehensive molecular diagnostic service for solid tumors analyzes the tumor genome to identify clinically relevant biomarkers, therapy options, and potential clinical trial matches. Hartwig has been working with Ultima’s first-generation sequencing system, the UG 100®, since 2024 to build deployable bioinformatics solutions and demonstrate the utility of Ultima’s new sequencing architecture for WGS in cancer testing and emerging applications such as liquid biopsy and minimal residual disease (MRD). With the addition of the UG200, Hartwig expands the scale, throughput, and breadth of its sequencing capabilities while continuing to reduce the overall cost of cancer testing and generating comprehensive genomic data across different oncology applications.

Ultima’s UG200 is powered by Ultima’s new Solaris 2.0 workflows, which provide significant advantages for deploying the UG200 into clinical laboratory settings. The simplified workflows employ an isothermal amplification process, instead of previously used emulsion-based amplification, and now integrate with standard laboratory automation and improve coverage uniformity across challenging genomic regions. The workflows reduce hands-on time, simplify operations, and are designed to support clinical-scale deployment and automation. The workflows also enable Ultima’s ultrasensitive ppmSeq technology, which provides single-digit part-per-million accuracy using WGS for applications like MRD.

“Whole-genome sequencing for oncology applications becomes transformative when it is paired with the accuracy of our flow-based chemistry and is no longer constrained by cost, capacity, or operational complexity,” said Gilad Almogy, CEO of Ultima Genomics. “Hartwig has already shown what is possible when comprehensive genomic information is connected to clinical decision-making. This next phase is about building the clinical infrastructure that enables WGS to become routine for oncology in global settings, while also opening the door to employing WGS in applications requiring deeper sequencing and extreme accuracy, such as MRD.”

A central objective of the expanded collaboration between Ultima and Hartwig is to further validate and implement Ultima’s ppmSeq technology for whole-genome-informed circulating tumor DNA (ctDNA) monitoring. Hartwig’s comprehensive tumor-genome foundation enables development of a pure WGS-based MRD approach without the operational burden of bespoke panel design, manufacturing, or patient-specific assay production.

Today, ppmSeq technology is the only broadly available, decentralized whole genome MRD workflow that can be implemented by clinical users in-house in global settings with ultra-sensitive levels of detection down to the single-digit ppm range.

This work is closely aligned with Hartwig’s clinical research direction in the Netherlands, including ongoing efforts for setting up clinical studies designed to evaluate blood-based ctDNA monitoring in patients already undergoing standard WGS-based molecular diagnostics at the Netherlands Cancer Institute (NKI). Findings from such studies are expected to help define the clinical utility, health-economic value, and implementation pathway for broader adoption of WGS-based disease monitoring in Dutch oncology care. Together, Hartwig and Ultima aim to generate evidence that supports not only technical feasibility, but also patient impact, cost-benefit assessment, and routine-care adoption.

“OncoAct WGS was built on the principle that the complete cancer genome can provide a more complete view of the patient’s disease, resulting in improved clinical actionability and more patient impact,” said Edwin Cuppen Scientific Director at Hartwig Medical Foundation. “With the UG200, we can extend that principle from therapy selection at diagnosis toward longitudinal, high-resolution disease monitoring using a one-size-fits all assay. The question is no longer whether WGS can provide value. The question is how quickly we can build the evidence, workflows, and clinical infrastructure to make that value available to more patients.”

Finally, the collaboration will also focus on building practical end-to-end workflows including extension of the Hartwig-developed comprehensive open-source cancer genomics tools (OncoAnalyser) to optimally support Ultima data and longitudinal ctDNA analysis to help the broader clinical genomics community implement Ultima technology in-house. Hartwig and Ultima intend to continue working together across laboratory automation, sample preparation, sequencing operations, data quality control, and bioinformatics.

About Hartwig Medical Foundation

Hartwig Medical Foundation is a Dutch nonprofit organization that operates globally with the mission to improve cancer patient care. They support data-driven treatment decisions through a combination of innovative software, clinical data analyses, and molecular diagnostics. This enables patients to timely receive the right treatment, while generating and making available valuable data that supports research, drug development,and the continuous improvement of care. 

About Ultima Genomics

Ultima Genomics is unleashing the power of genomics at scale. The Company’s mission is to continuously drive the scale of genomic information to enable unprecedented advances in biology and improvements in human health. With humanity on the cusp of a biological revolution, there is a virtually endless need for more genomic information to address biology’s complexity and dynamic change—and a further need to challenge conventional next-generation sequencing technologies. Ultima’s revolutionary new sequencing architecture drives down the costs of sequencing to help overcome the tradeoffs that scientists and clinicians are forced to make between the breadth, depth and frequency with which they use genomic information. The new sequencing architecture was designed to scale far beyond conventional sequencing technologies, lower the cost of genomic information, and catalyze the next phase of genomics in the 21st century. To learn more, visit www.ultimagenomics.com

Media contacts:

Ultima Genomics: Vikki Herrera, Oak Street Communications, 408-206-7009, vikki@oakstreetcommunications.com

Hartwig Medical Foundation: Edwin Cuppen, Scientific director, info@hartwigmedicalfoundation.nl, +31 20 226 9700

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SOURCE Ultima Genomics

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Submarine Networks World x Subsea Security World 2026 – enacting GUIDE starts here!

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September 10, 2026

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Submarine Networks World x Subsea Security World 2026: the flagship annual event for the global subsea industry returns to Singapore

SINGAPORE, Sept. 10, 2026 /PRNewswire/ — Submarine Networks World 2026 (organised by Terrapinn), steps up another level and will be welcoming over 1,500 subsea fibre leaders and 150+ industry speakers from across the globe to Sands EXPO & Convention Centre in Singapore on September 23rd and 24th.

The introduction of the new Subsea Security World theatre, focused on the biggest talking point of the last twelve months, increases attendance and participation from security sector specialists, national and regional government entities, navy, coastguard, policymakers and academics from the Americas, Europe, Asia, Oceania.

“Subsea cables connect the world and protecting them has never mattered more. With the launch of Subsea Security World alongside our flagship event, 2026 brings together the commercial and security sides of the industry in one place for the first time. We’re thrilled to welcome back the global subsea community, as well as the policy makers and defence specialists shaping its future, to Singapore for what will be the largest edition yet, and the edition the industry has been waiting for”, Paul Clark, Managing Director (Asia), Terrapinn.

Everyone from cable owners/operators, consortium members, technology providers, innovators, consultants, service partners, government entities, financiers, surveying companies – the whole industry – will be onsite at the true ‘one-stop shop’ for any subsea cable project.

Meet with more than 80 sponsors, exhibitors and partners, including Title Sponsor – Nokia, Diamond Sponsors – Ciena and HMN Tech and Gold Sponsors ASN, APTelecom, BAE Systems, Center3, Digital Realty, EXFO, FiberHome, Fibersense, Huawei, Prysmian, ShinewayTech, SMD, Solwake, Starboard Maritime Intelligence and Telecom Egypt.

Attendees will hear from 150+ influential speakers from every inhabited continent around the world. Both mornings begin with the daily Keynote sessions, followed by 4 specialist theatres each day – Strategy, Cable, Data Centres & CLS, Network, O&M and Subsea Security World.

Keynote Speakers include:

Alan Mauldin, Research Director, TeleGeography Andy Palmer-Felgate, Submarine Cable Engineer, MetaGiuseppe Valentino, VP Product Management, Backbone & Infrastructure Solutions, SparkleNelson McMillan, Royal Navy Maritime Domain Awareness Adviser, Southeast Asia, UK Ministry of DefenceKent Bressie, Partner – HWG LLP / Legal Advisor, ICPC Nadia Krivetz, Director, Cable Resilience & Connectivity Centre, DFAT AustraliaCaptain Brett Dawe, Chief of Navy Liaison Officer to the Republic of Singapore Navy, Royal Australian NavySean Bergin, President & Co-Founder, APTelecomBevan Slattery, Founder, SUBCOMark Procter, Deputy CEO, Stavian HighTech InfrastructureAmbrogio Michetti, Chief Corporate & Revenue Officer, SparkleAmajit Gupta, Group CEO and MD, LightstormJim Fagan, Chief Executive Officer, EXA InfrastructureSasha Pearson, Policy Analyst, European Centre for Development Policy Management (ECDPM)Woon Sien Loh, Senior Director, Infrastructure Planning & Market Development, Info-Communications Media Development Authority (IMDA)Emily Kiernan, Head of Strategy and Investments, Telstra Digital InfrastructureRobert Pepper, Senior Fellow, Global Digital Inclusion PartnershipWalid Wakim, Chief Technology Officer of Systems, NokiaSavy Wei, Senior Network Solution Manager, HMN TechAmit Malik, Vice President, APJI Sales, Ciena

For event information and the full conference agenda, visit https://www.terrapinn.com/ExperienceSNW2026

PRNewswire is the Official Media Partner of Submarine Networks World x Subsea Security World 2026.

Press attendance is complimentary. Enquiries should be directed to:
Jessica Foong
Terrapinn Pte Ltd
Jessica.foong@terrapinn.com

About Submarine Networks World x Subsea Security World 2026:
Submarine Networks World x Subsea Security World 2026 will take place on 23-24 September 2026 at Sands Expo & Convention Centre in Singapore. Firmly established as the world’s largest annual gathering of the global subsea communications community, Submarine Networks World is the dedicated platform to exchange knowledge, explore the latest projects, develop strategies and form lucrative new partnerships to drive the industry forward. For 2026, Subsea Security World joins the event for the first time, bringing together the public, private and policy-making stakeholders shaping the future of cable security and protection.

About Terrapinn: 
Terrapinn has been sparking ideas, innovations and relationships that transform business for over 30 years. Using our global footprint, we bring innovators, disrupters and change agents together, discussing and demonstrating the technology, strategies and personalities that are changing the way the world does business. Whether you’re looking to make new connections, introduce a product or inspire change in your industry, we invite you to join us as agitators of change. Terrapinn – spark something.

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SOURCE Terrapinn Pte Ltd

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Iyuno’s Strategic Approach: Multi-Agent AI, Built Around Context

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20 minutes ago

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September 10, 2026

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Specialized AI agents are becoming an industry-wide shift. Iyuno applied that approach to one of media’s hardest problems: giving AI a memory that holds up across scenes, episodes, and seasons.

BURBANK, Calif., Sept. 10, 2026 /PRNewswire/ — Iyuno, the world’s largest media localization company, today detailed the multi-agent engineering behind CLOE’s Contextual Memory, built on the belief that applying specialized AI agents to a narrow, well-defined problem outperforms brute-force scale.

Most enterprise AI deployments chase scale — bigger models, bigger context windows, bigger compute bills — and still lose narrative continuity across long-form video. CLOE takes a different approach, built on three principles:

Vertical Multi-Agent Orchestration. Instead of one monolithic model, a network of hyper-specialized micro-agents each performs a specific function, such as character relationship mapping, emotional intent, prosodic matching, or brand compliance, instead of relying on a single system to perform every task.High-Density, Low-Token Prompting. Raw video, audio, and script are synthesized into a structured knowledge graph first; agents work from compressed, high-signal context vectors instead of massive raw inputs, cutting token consumption and inference cost per title.Persistent Graph Memory. Agent outputs converge into one persistent ontology graph instead of being discarded after each task, so understanding compounds across a title, season, or franchise without compounding inference cost.

“Our focus was never building the biggest AI system—it was building the right one for media,” said David Lee, Founder & CEO of Iyuno. “For a broad, general-purpose problem, bigger models and more compute make sense. For a specialized domain like entertainment, that scale doesn’t buy you the thing that actually matters: narrative continuity. Specialized agents working off precise, high-density context get us state-of-the-art understanding at a fraction of the footprint, and that footprint doesn’t grow with catalog size the way monolithic approaches do. Every title we process makes the graph more capable, not more expensive to run.”

This architecture already runs Iyuno’s commercial suite: CLOE Enterprise (SaaS), CLOE Sub, CLOE Script, CLOE Dub, and CLOE Live — in live studio and streaming production today. Future announcements will detail how it extends into CLOE Skills across accessibility, marketing, and additional workflows.

About Iyuno

Iyuno (www.iyuno.com) is a leading provider of localization services for the media and entertainment industry. Trusted by top entertainment brands and creators worldwide, Iyuno offers comprehensive end-to-end localization services from 40 offices across 29 countries. Backed by a team of exceptional creative and technical talent, state-of-the-art facilities, and cutting-edge technologies, Iyuno proudly boasts the largest global footprint amplifying its dubbing, subtitling and media services offerings. The company is also the creator of CLOE, a contextual intelligence platform that transforms content into structured understanding, enabling AI-powered workflows across localization, accessibility, marketing, and emerging content experiences.

 

View original content to download multimedia:https://www.prnewswire.com/news-releases/iyunos-strategic-approach-multi-agent-ai-built-around-context-302875036.html

SOURCE Iyuno

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Nel ASA: Enters framework agreement with Hydrasun as a European integration partner for PEM electrolyser solutions

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September 10, 2026

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OSLO, Norway, Sept. 10, 2026 /PRNewswire/ — Nel ASA (Nel) (OSE: NEL) has entered into a framework agreement with Hydrasun to establish dedicated assembly and integration capabilities for the MC Series, Nel’s modular and scalable PEM technology platform. With this partnership, Nel gains an experienced integration partner in Europe, complementing its existing integration setup in the US and widening its delivery capabilities for the European market. Nel’s PEM stack production will continue at Nel’s Wallingford, Connecticut facility in the US.

Under the agreement, Hydrasun will develop production capabilities for the assembly and integration of Nel’s containerized PEM technology platform. Hydrasun will procure, integrate, and manufacture the balance of plant systems surrounding the electrolyser stack, enabling delivery of a fully integrated, modular, and containerized electrolyser offering, while stack production continues to be done by Nel from its Wallingford facility. The collaboration gives Nel an experienced integration partner in Europe at a time of growing demand for standardized, modular electrolyser solutions. It will expand Nel’s manufacturing flexibility and strengthen supply chain resilience, while bringing production capabilities closer to key growth markets. Hydrasun’s initiative is supported by the Scottish Government’s Just Transition Fund and will see Hydrasun invest in and upgrade its Aberdeen facilities to support clean technology manufacturing.

“This agreement marks a defining moment in Hydrasun’s evolution. For 50 years we’ve supported the energy industry in the areas of fluid transfer, power and control solutions, and clean energy, this investment builds directly on that industrial capability,” says James Gaskell, Chief Executive at Hydrasun. “Establishing Scotland’s first electrolyser assembly and integration facility is a proud milestone for the company and an important step forward for Aberdeen’s energy sector more broadly, ensuring the city has genuine clean energy manufacturing capability.”

The project is expected to contribute to the development of Scotland’s clean energy manufacturing sector by building on existing industrial competence in Aberdeen, supporting skills development, supply chain activity, and high-value employment. Hydrasun has stated that the initiative has the potential to create up to 12 new jobs while safeguarding a further 11 existing roles.

“We are pleased to be working with Hydrasun to establish an experienced European integration partner for our standardized PEM electrolyser solutions, the MC Series. As demand for standardized, modular systems grows, this collaboration enhances our ability to serve key markets while creating greater flexibility and scalability across our production network,” says Tushar Ghuwalewala, SVP PEM Operations at Nel.

For additional information, please contact:

Kjell Christian Bjørnsen, CFO, +47 917 02 097
Wilhelm Flinder, Head of IR, Communications and Marketing, +47 936 11 350

About Nel ASA | www.nelhydrogen.com 

Nel has a history tracing back to 1927 and is today a leading pure play hydrogen technology company with a global presence. The company specializes in PEM and Alkaline electrolyser technology for production of renewable hydrogen. Nel’s product offerings are key enablers for a green hydrogen economy, making it possible to decarbonize various industries such as transportation, refining, steel, and ammonia.

This information was brought to you by Cision http://news.cision.com

https://news.cision.com/nel-asa/r/nel-asa–enters-framework-agreement-with-hydrasun-as-a-european-integration-partner-for-pem-electrol,c4392033

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