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Colossal Foundation and University of Tasmania Partner to Combat Devil Facial Tumour Disease with Vaccines and Gene Editing
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4 months agoon
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The collaboration leverages Colossal’s marsupial de-extinction and conservation biotechnology platform to save the Tasmanian devil from a contagious cancer that has driven 80% population declines across Tasmania
DALLAS and HOBART, Australia, July 1, 2026 /PRNewswire/ — The Colossal Foundation, the nonprofit conservation arm of Colossal Biosciences, today announced a new partnership with the University of Tasmania to support efforts to combat Devil facial tumour disease (DFTD), a fatal transmissible cancer that has devastated wild Tasmanian devil populations and threatens the iconic marsupial with extinction.
Under the partnership, the Colossal Foundation will support the establishment of a fat-tailed dunnart research colony at the Menzies Institute for Medical Research at the University of Tasmanian, Hobart. The two teams will also collaborate on gene-editing capabilities to advance DFTD vaccine testing and explore the long-term potential of heritable resistance to transmissible cancers in dasyurid marsupials which includes the Tasmanian devils. The collaboration extends the marsupial biotechnology platform Colossal has built through its thylacine de-extinction program, and joins a growing portfolio of marsupial conservation initiatives in Australia that includes a world-first demonstration of engineered cane toad toxin resistance for the endangered northern quoll.
“Devil facial tumour disease is one of the most devastating wildlife diseases on Earth. This contagious cancer is pushing an iconic marsupial toward collapse, with consequences for the ecology of an entire island,” said Matt James, Executive Director of the Colossal Foundation. “Andy Flies and his team at the University of Tasmania have built the most advanced DFTD vaccine pipeline in existence. By combining that work with Colossal’s marsupial husbandry, reproductive science, and gene-editing platform, we have a real opportunity to accelerate this effort and give the Tasmanian devil a fighting chance.”
A CONSERVATION CRISIS WITHOUT MODERN PRECEDENT
The Tasmanian devil (Sarcophilus harrisii), the world’s largest living carnivorous marsupial, is threatened by two independent transmissible cancers: Devil facial tumour 1 (DFT1), was discovered in 1996 and has since spread across most of the species’ range. The second, DFT2, was identified in 2014 in southern Tasmania and is still emerging. Both cancers cause large tumours around the mouth and face that can prevent devils from eating, and both are nearly 100% fatal. The disease is transmitted directly between devils through biting, a behaviour central to feeding and mating, making it almost impossible to control by conventional means.
Wild devil populations have collapsed by approximately 80% since DFTD’s emergence. As Tasmania’s apex scavenger and predator, devils play an important ecological role, helping suppress feral cats and reducing pressure on smaller native species. Their decline has had cascading effects across Tasmania’s ecosystems, making DFTD not only a species-level crisis, but a much broader conservation problem.
A TWO-PART STRATEGY: VACCINES + GENE EDITING
The University of Tasmania Wild Immunology Group, led by Associate Professor Andrew Flies, Ph.D., has been developing a two-pronged strategy to help the devil immune system recognize and fight DFTD. The first prong is an advanced vaccine program. Flies’s team has developed a field-ready oral bait vaccine designed to train the devil immune system to recognize and destroy DFT1 and DFT2 cells, and that could one day protect wild devils across the Tasmanian landscape without requiring every animal having to be trapped and injected.
The second prong is a gene-editing strategy centered on LZTR1, a gene that is connected to cancer-relevant pathways in other species, and is hypothesized to play an important role in the origin and biology of devil facial tumors. Tasmanian devils carry two unusual amino-acid substitutions in LZTR1 that are not found in other mammals, and the “shattering” of one copy of the LZTR1 gene has been identified as a potential driver event in the origin of DFT1. The partnership between Colossal and University of Tasmania will explore whether targeted editing of the devil-specific LZTR1 mutations to match the ancestral mammalian sequence could reduce the underlying susceptibility of devils to these transmissible cancers.
Under the partnership, the LZTR1 gene-editing work will advance on two complementary tracks. The Colossal Australia team in Melbourne will edit LZTR1 in fat-tailed dunnart induced pluripotent stem cells (iPSCs), while the Anuk Kruawan, Ph.D. at University of Tasmania will edit LZTR1 in devil cell lines. Results from these complementary approaches will determine whether LZTR1 biology is relevant to future disease-resilience strategies
“We’ve spent years developing a vaccine designed to train the devil immune system to fight these cancers but progress is slow due to the challenges of working with an endangered species and having a lack of marsupial research tools,” said Associate Professor Andrew Flies at Menzies Institute for Medical Research, University of Tasmania. “We won’t know if the vaccine is effective until we perform field trials with naturally-infected devils. However, before we can start field trials, we need to make sure the vaccine is safe and induces a strong immune response in devils and other species that could eat a vaccine bait. Partnering with the Colossal Foundation can significantly accelerate our vaccine work, and allow us to explore a gene-editing strategy in parallel that could enhance the vaccine and make devils more resistant to DFTD.”
A DE-EXTINCTION PLATFORM, DEPLOYED FOR DEVILS
Testing a new vaccine and gene-editing approach in a marsupial system requires specialised facilities, careful adherence to regulatory requirements, and biologically appropriate models. The fat-tailed dunnart (Sminthopsis crassicaudata), a small, mouse-sized dasyurid that is a close evolutionary relative of both the Tasmanian devil and the thylacine, provides that bridge.
The Colossal Foundation is supporting the University in establishing a dedicated dunnart colony in the Menzies Institute for Medical Research facility in Hobart, with Colossal Australia’s animal-care team hosting University of Tasmania veterinarians and animal services staff to transfer husbandry, breeding, and welfare protocols developed through years of dunnart colony management. Once operational, the Hobart colony will allow vaccine safety and immunogenicity trials to be run in a biologically relevant marsupial model. This is a critical regulatory and scientific step toward devil trials and eventual field deployment.
Colossal’s work has made the fat-tailed dunnart one of the most important marsupial models in the world. Through the thylacine de-extinction program, Colossal and the University of Melbourne have advanced dunnart biology through the development of a complete genome, cell lines, induced pluripotent stem cells (iPSCs), genome editing, assisted reproductive technologies, and husbandry systems. Those same tools are now being applied to conservation challenges facing living species, including the Colossal Foundation’s northern quoll project, which uses the dunnart as a closely related model to test gene-editing strategies for cane toad toxin resistance.
“The dunnart has become the foundation of Colossal’s marsupial platform,” said Andrew Pask, Chief Biology Officer at Colossal Biosciences. “To build the thylacine program, we had to develop tools for marsupial cell culture, gene editing, reproductive biology, and husbandry that simply did not exist at this level before. Now those tools can be applied to living species. Bringing that platform into the Tasmanian devil cancer effort with the University of Tasmania is a powerful example of how de-extinction science can deliver immediate conservation value for living species.”
“This partnership reflects exactly why Colossal exists,” said Ben Lamm, Co-Founder and CEO of Colossal. “Our de-extinction programs are fueling the development of entirely new biological tools and platforms. In Australia, the work we are doing to bring back the thylacine has already helped establish the dunnart as a powerful model for marsupial genomics and reproductive science. We’re now deploying those same technologies against one of the most devastating wildlife diseases on Earth. This is what the conservation power of de-extinction looks like.”
A REGIONAL ECOSYSTEM OF CONSERVATION PARTNERS
The DFTD partnership joins a growing network of Tasmanian and Australian conservation organizations engaged with Colossal’s marsupial work. Bonorong Wildlife Sanctuary, Tasmania’s leading wildlife rescue, rehabilitation, and conservation organizations, expressed strong interest in the project and in its potential relevance for Tasmanian devil conservation. Bonorong’s work on the front lines of wildlife care gives it a direct understanding of the stakes of devil recovery and the importance of developing new tools to support the species.
“For nearly thirty years, we have watched DFTD mercilessly take countless devils from the Tasmanian landscape. At Bonorong we’ve cared for hundreds of Devils as this horrific plague rages on,” said Greg Irons, Director of Bonorong Wildlife Sanctuary. “Anything that gives our devils a real path back deserves our full support.”
The partnership also has the backing of the Tasmania Thylacine Advisory Committee (TTAC), a group of Tasmanian community, conservation, business, and local leaders assembled to guide Colossal’s work in Tasmania.
“The Tasmanian devil is one of the most iconic endangered species on Earth — recognised globally, but with deep roots in Tasmania’s wild landscapes and identity,” said Michelle Dracoulis, Mayor of the Derwent Valley Council and Chair of the TTAC. “What Associate Professor Andrew Flies and his team have built in Hobart is genuinely world-class. Seeing that work strengthened through the support of the Colossal Foundation gives real hope for the future of the species, and demonstrates how emerging technologies can be applied directly to urgent conservation challenges. The TTAC is pleased to support this partnership and the opportunities it creates for globally significant conservation science aimed at protecting Tasmania’s devils.”
Beyond Tasmania, the new collaboration complements Colossal’s broader Australian conservation partners network. Aussie Ark, one of Australia’s foremost private conservation organizations, is a leader in Tasmanian devil insurance population breeding on the mainland, and Zoos Victoria has a long-standing partnership with Colossal on the conservation of the Critically Endangered Victorian Grassland Earless Dragon.
“Every major conservation challenge teaches us something different,” said Andrew Pask, Chief Biology Officer at Colossal. “With the thylacine, we are building the tools to reverse extinction. With the northern quoll, we are applying those tools for resilience to invasive-species. With the Tasmanian devil, we are now applying them to infectious cancer, one of the most extraordinary disease problems in vertebrates. That is the future of disruptive conservation: build the platform once, then move it quickly and responsibly wherever biodiversity needs it most.”
ABOUT THE COLOSSAL FOUNDATION
The Colossal Foundation is a 501(c)(3) dedicated to supporting the use of cutting-edge technologies to conservation efforts globally to help prevent extinction of keystone species. The organization deploys cutting-edge de-extinction technologies and support to empower partners in the field to reverse the extinction crisis. www.ColossalFoundation.org.
ABOUT THE UNIVERSITY OF TASMANIA AND THE MENZIES INSTITUTE FOR MEDICAL RESEARCH
The University of Tasmania is Australia’s fourth-oldest university and the only university based in Tasmania, with a deep institutional commitment to research that addresses the unique conservation, health, and environmental challenges of its island state. The Menzies Institute for Medical Research, University of Tasmania’s flagship medical research institute, is one of Australia’s leading health and medical research institutes. The Menzies Wild Immunology Group, led by Associate Professor Andrew Flies, focuses on wildlife immunology and vaccine development, including efforts to protect Tasmanian devils from devil facial tumour disease. Learn more at menzies.utas.edu.au.
ABOUT BONORONG WILDLIFE SANCTUARY
Established in 1981, Bonronog Wildlife Sanctuary is an iconic enterprise committed to the conservation of native species, through wildlife rescue and rehabilitation, education, and experiences that connect people and wildlife. Learn more at bonorong.com.au.
WEBSITE & SOCIALS
Websites: www.colossal.com
Instagram: https://www.instagram.com/colossal/
YouTube: https://www.youtube.com/@colossal
Twitter: https://x.com/colossal
LinkedIn: https://www.linkedin.com/company/colossal/
Facebook: https://www.facebook.com/itiscolossal
TikTok: https://www.tiktok.com/@colossal
BlueSky: https://bsky.app/profile/itiscolossal.bsky.social
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SOURCE Colossal Biosciences Inc.
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BEIJING, Oct. 18, 2026 /PRNewswire/ — An interview from China.org.cn with Wang Xiaohui and David Ferguson on the Long March:
David Ferguson:
This is the Yudu River. One dusk in October, 1934, more than 86,000 soldiers of the Red Army crossed this river and embarked on the Long March, a two-year saga that has left its mark in history.
Yet, lingering here by the river, I am struck by a simple question: If you have faith in a bright future, and reality seems to thwart you at every turn, where do you find the moral strength to keep believing?
Wang Xiaohui:
At dusk on Oct. 17, 1934, an army of more than 86,000 troops gathered along the banks of the Yudu River. Over 800 boats of all sizes floated on the water, bound together with planks collected from villagers’ home gates, timber beams, and even coffin boards reserved for elderly locals. The people of Yudu built this pontoon bridge, determined to help the army led by the Communist Party of China (CPC) cross the river.
At that time, no one knew that the great expedition embarked upon by the banks of the Yudu River would go on to transform China and exert far-reaching influence across the world.
China in the 1920s and 1930s was plagued by chaos and despair.
The Kuomintang (KMT), the ruling party back then, was not capable of unifying the nation, leaving warlords locked in endless fighting. In 1931, Japanese invaders launched an assault on northeastern China, beginning their invasion. Crushed under domestic turbulence and foreign aggression, countless civilians were displaced, with many even starving to death on the streets; in certain regions, severe drought resulted in zero harvests, yet the farmers were forced to pay land taxes assessed for more than a decade into the future.
Amid this turmoil, the only glimmer of hope for the Chinese nation was kindled by the revolution ignited by the Communist Party of China.
The CPC, dedicated to winning liberation for the people and national independence, built contingents of workers’ and peasants’ Red Army troops and revolutionary base areas across the countryside. Impoverished farmers were granted land ownership, as well as unprecedented political dignity. On Nov. 7, 1931, the Chinese Soviet Republic was officially proclaimed in Ruijin, then a small village in southeastern China’s Jiangxi Province, establishing a Soviet system under which workers, peasants and soldiers elected representatives to run regional affairs and make policies.
The communist ideal of a fair society free from exploitation and equality for all blazed like a spark in the darkness; it kindled hopes among impoverished Chinese and became the wellspring of faith that enabled the Red Army — a force made up of poor workers and peasants — to overcome all hardships in the days to come.
Yet, bright as the spark was, it burned thin and fragile at times. Could this flame still endure when the ideals it carried were repeatedly battered by harsh reality?
In September 1933, flocks of warplanes clouded the skies over the Red Army’s revolutionary base areas. By then, Japanese invaders were steadily advancing towards North China, but Chiang Kai-shek’s KMT turned a blind eye to the looming national crisis. They mobilized over a million troops and more than 200 aircraft to launch a massive offensive at the Red Army’s base areas. Over the previous three years, Chiang Kai-shek had mounted four major military “encirclement” campaigns aimed at exterminating the Red Army, but all ended in failure. He was desperate for a pivotal victory to restore his prestige and to wipe out the CPC and the Red Army.
At the time, the commander of the Red Army abandoned mobile warfare tactics pioneered by Mao Zedong and other commanders, opting instead for rigid positional warfare involving conventional head-on clashes. But the reality was, some Red Army units didn’t even possess a single light machine gun; how could they confront the heavily-armed KMT army head-on?
Zhong Ming, a Red Army medic, could never erase the memories of gravely wounded soldiers being carried to his aid station. He remembered how a soldier whose chest was blown open begged his comrades to end his life. At the frontline, a whole battalion of Red Army soldiers religiously followed orders to defend crude earth-and-wood bunkers, but under the constant barrage of KMT artillery and airstrikes, every soldier in the battalion laid down their lives; not a single man survived.
What’s more heart-wrenching is that no matter how fearlessly the Red Army fought, the steep imbalance in military strength, paired with erroneous military command led to irreversible losses. By October 1934, the KMT’s iron-clad encirclement closed menacingly around Ruijin.
Faced with this dead-end, what decision would you make?
This stood as the most agonizing decision for the Red Army. The biggest challenge lay not in sacrificing one’s life for an ideal, but in finding a way to keep the revolutionary cause alive.
To stay meant defeat — the Red Army had no room to maneuver within the Central Revolutionary Base Area. To break through the encirclement, however slim the odds, offered a fighting chance. Preserving the Red Army as a living force mattered much more than clinging to isolated strongholds. Where the spark survives, the path ahead remains lit.
The air already turned chilly in October. Units of the Central Red Army assembled in Yudu to prepare for a strategic shift. The plan was kept strictly classified; none of the soldiers knew they were evacuating the base areas, only sensing an unusual vibe.
At dusk on Oct. 17, crowds lined up at the Yudu riverbank. Tens of thousands of villagers flocked from every corner to see the Red Army off. They walked alongside the marching columns, slipping food like eggs and glutinous rice balls into the soldiers’ pockets, praying for their swift homecoming.
The main force of the Central Red Army set off. Within days, they left behind revolutionary base areas where they had survived, grown and taken root. No one anticipated that the journey they embarked on would become the Long March, a trek spanning over 10 provinces. Still less could anyone imagine that this journey would ultimately pave the way for a brand-new China.
Looking back on this chapter of history, many claim that the Red Army only set out on this expedition because the enemies left them no other choice. To a degree, yes, the Long March was indeed a forced strategic shift, yet this fact does nothing to diminish its greatness and glory.
The ordinary Red Army soldiers had no idea how far they would march, or where they were heading. But they clung firmly to their founding mission: to deliver liberation for the people and independence to the nation. This unswerving conviction kept them from disintegrating through countless perils, sustaining them as they marched into the unknown with resolve.
David Ferguson:
I now realize that faith and ideals untested by harsh reality may have no true substance.
Since its founding, the Communist Party of China has always upheld the realization of communism as its fundamental goal. Despite devastating losses and extreme adversity, the Red Army continued to press forward resolutely and never faltered. Its inner strength came from an unshakable belief in the cause, an unwavering commitment to the founding aspiration, and a profound sense of mission. The Red Army was never fleeing pursuers in search of safety; it was marching forward to a future in which it had a steadfast belief.
Wang Xiaohui:
The Long March went on for two years. The Red Army trekked 25,000 li across some of China’s harshest terrain, but they kept their heads high, seeking hope amid despair and marching towards light through unending darkness. The lofty ideals and sense of mission they upheld have also become the torch that guides generations of CPC members in the following centennial, tempering them into steel as they press forward unswervingly toward national rejuvenation.
That spark lit along the Yudu River has never dimmed since.
China Mosaic
http://www.china.org.cn/video/node_7230027.htm
Faith: The Spark Born by the Yudu Riverside
http://www.china.org.cn/2026-10/16/content_118736835.shtml
View original content to download multimedia:https://www.prnewswire.com/news-releases/faith-the-spark-born-by-the-yudu-riverside-302911977.html
SOURCE China.org.cn
Technology
Linktel Technologies Highlights Breakthrough 1.6T LPO Performance & Strong Market Pull at OCP 2026
Published
9 hours agoon
October 18, 2026By
SAN JOSE, Calif., Oct. 18, 2026 /PRNewswire/ — At the recent 2026 OCP Global Summit, Linktel Technologies showcased its cutting-edge optical interconnect portfolios engineered specifically for next-generation AI computing networks. Among the heavy lineup, Linktel’s 1.6T Linear Pluggable Optics (LPO) solutions commanded immense industry attention, drawing heavy customer interest for their unprecedented energy efficiency, ultra-low latency, and supply-chain resilience.
Spotlight: 1.6T LPO Performance & High Customer Traction
AI data centers face immense scaling pressures, demanding higher bandwidth densities with tighter thermal and power budgets. Linktel’s 1.6T LPO solutions—highlighted by the 1.6T LPO 2DR4—delivered standout performance metrics that captured the spotlight at the summit:
Ultra-Low Power Consumption: Operates with power consumption as low as an impressive 10W, drastically mitigating data center cooling and power loads.Minimal Latency: Features a linear optics architecture that cuts down signal processing delays, making it a critical asset for high-performance AI scale-out fabrics.Enhanced Supply-Chain Resilience: Eliminating the optical DSP mitigates component choke points, ensuring robust scalability for mass deployments.Proven Interoperability: Following its breakthrough performance and multi-switch platform interoperability at the early September 2026 1.6T LPO-MSA Plugfest, Linktel has laid a solid foundation for the 200G-per-wavelength ecosystem.
Surging Market Interest
Throughout OCP 2026, Linktel’s live demonstrations of its 1.6T LPO, LRO, and FRO modules drew crowds of data center architects and industry partners. With volume production already in place, Linktel is fully equipped to meet the exploding market demand for energy-efficient, high-density 1.6T connectivity.
Overview of Other Innovations at OCP 2026
In addition to the heavily requested 1.6T LPO lineup, Linktel showcased two other major high-speed architectural pillars:
12.8T Liquid-Cooled XPO:Featured a live thermal demonstration integrating advanced liquid cooling to guarantee stable operations in high-density AI nodes.As a founding member of the XPO MSA, Linktel is actively scaling XPO series with FRO, LRO, and LPO variants for comprehensive scale-up, scale-out, and scale-across frameworks.6.4T/7.2T NPO Modules:Displayed with covers removed to reveal internal architectural designs supporting both ELS and ILS configurations.Combines compact high density with low power and low latency, backed by an established 6.4T/7.2T NPO roadmap.DMD Technology & Executive Presentation:Linktel Engineer Director Dr. Grace Zhang hosted a heavily attended Executive Session titled “Dispersion Managed Transceiver for Next-Gen AI Fabrics,” detailing cost-effective 800G (20km) and 1.6T (10km) solutions for OCS SuperPOD architectures, as well as the feasibility of 400G per lambda (3km).With its DMD product line already in volume production, Linktel actively calls upon ecosystem partners to join forces in collaborative development. To drive ecosystem maturity, Linktel is open to sharing its U.S.-filed patents, paving the way for industry-wide adoption and advancements in next-gen AI fabrics.
About Linktel Technologies
Linktel Technologies is a global leader in optical transceiver development and manufacturing, supplying high-speed optical I/O connectivity—including pluggable transceivers, optical engines, and ODM/JDM services.
For more information, visit www.linktel.com or follow Linktel Technologies on LinkedIn.
View original content:https://www.prnewswire.com/news-releases/linktel-technologies-highlights-breakthrough-1-6t-lpo-performance–strong-market-pull-at-ocp-2026–302911973.html
SOURCE Linktel Technologies
Technology
Advanced Manufacturing in Focus: Smart Life and Robotics Take the Spotlight at 140th Canton Fair
Published
10 hours agoon
October 18, 2026By
GUANGZHOU, China, Oct. 18, 2026 /CNW/ — Phase 1 of the 140th Canton Fair, themed “Advanced Manufacturing,” opened on October 15 and will run through October 19. As one of the event’s most closely watched sections, the Consumer Electronics and Information Products zone once again serves as a showcase for the latest achievements in China’s manufacturing and technology industries.
Smart Life Solutions Address an Aging and Globalized Market
A highlight of this section is the focus on smart living, which brings together smart solutions designed to support healthier, safer, and more independent lifestyles.
For example, wearable devices and continuous glucose monitoring systems enable convenient tracking of key health indicators such as heart rate and blood glucose levels. Meanwhile, wearable exoskeletons and other AI-powered devices support mobility training and functional recovery. For home and elderly care, companion robots, electric nursing beds and home-use hyperbaric oxygen chambers, offer a combination of daily care, wellness support and lifestyle assistance. All these solutions highlight a growing shift toward technology-enabled living, where health management, personal care, and independent living are becoming more accessible and connected.
Service Robots Demonstrate Expanding Real-World Applications
The Service Robot Zone remains one of the fair’s most popular attractions in this edition.
Among the crowd favorites is a humanoid robot standing roughly 70–80 centimeters tall. With its expressive movements and playful appearance, the robot draws constant attention as it dances, approaches visitors and occasionally performs flips to the delight of onlookers. Behind the product is a company that has overcome key challenges in compact joint modules and modular humanoid robot development. Its independently developed high-power-density joints deliver remarkable agility and explosive movement, while modular architecture provides flexibility for a wide range of future applications.
More broadly, the Service Robot Zone features exhibits spanning a wide range of application areas, including embodied intelligence, specialized operations, urban services, and smart living. Full-size humanoid robots, dexterous hands with multimodal sensing capabilities and wheeled robots highlight the latest advances in artificial intelligence, perception technologies and motion control. For demanding industrial and emergency environments, exhibitors are presenting robotic inspection systems, live-line maintenance robots and underwater propulsion robots designed to improve safety and operational efficiency.
The commercial services sector is also well represented through reception robots, façade-cleaning robots and fully automated coffee kiosks, while everyday life applications include wearable exoskeletons, robotic lawn mowers and educational robots for home use. Together, these exhibits demonstrate how China’s robotics industry is accelerating its transition from technological innovation to large-scale commercialization.
As the 140th Canton Fair gets underway, the showcased innovations highlight China’s growing strength in advanced manufacturing, turning cutting-edge technologies into practical, market-ready solutions for global customers.
For more convenient attendance, please click here for pre-registration:
https://buyer.cantonfair.org.cn/register/buyer/email?source_type=16
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SOURCE Canton Fair
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