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CREATE Medicines Expands Targeted In Vivo CAR Platform Through Strategic Research Collaboration and Exclusive License Agreement with Monash University

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Broadens CREATE’s delivery toolkit with access to Monash’s novel LNP chemistries and next-generation targeting technologies.Enables rapid evaluation of diverse binder formats and cell-targeting strategies, accelerating development across multiple immune cell types and therapeutic programs.

CAMBRIDGE, Mass., July 31, 2026 /PRNewswire/ — CREATE Medicines, Inc. (“CREATE”), a clinical-stage biotechnology company pioneering in vivo immune programming, today announced a strategic research collaboration with Australia’s Monash University and its world-leading Monash Institute of Pharmaceutical Sciences (MIPS). The partnership broadens CREATE’s portfolio by accessing Monash’s advanced lipid nanoparticle (LNP) technology including proprietary binders and chemistry, strengthening its leadership in developing best-in-class targeted in vivo therapies. Targeted delivery remains one of the primary challenges in realizing the full therapeutic potential of in vivo cell therapies, requiring increasingly precise control over which immune cells receive therapeutic payloads.

Together, CREATE and MIPS will jointly advance targeted Chimeric Antigen Receptor (CAR) therapy, with the goal of enabling precise, cell-type-specific in vivo delivery of CAR payloads utilizing the targeted LNP technology. Under the agreement, CREATE receives a worldwide exclusive license to all intellectual property arising from the collaboration, together with the right to develop and commercialize CAR products directed to designated CAR targets. In turn, MIPS will receive research funding and downstream milestone and royalty payments.

“Monash brings world-class LNP engineering and paired with our already clinically validated and targeted mRNA platform, we can further apply that precision across an even broader range of targets,” said Daniel Getts, PhD, Founder and Chief Executive Officer of CREATE Medicines. “Together, we will unlock a new generation of programmable medicines that reach more patients than ever before.”

“Monash has built deep expertise in targeted LNP delivery, and their binder and chemistry innovations pair powerfully with our in vivo CAR platform,” said Robert Hofmeister, PhD, Chief Scientific Officer of CREATE. “Together we’re building a richer targeting toolkit with new binder formats and control that gives us even more ways to program the right cells with precision.”

“Our new strategic partnership with CREATE Medicines will accelerate the work of Monash’s world leading pharmaceutical researchers to design new immunotherapies and speed the translation of their work into new life-changing cancer treatments,” Monash Vice-Chancellor and President Professor Sharon Pickering said. “As a globally ranked top-40 university and the most industry-connected university in Australia, Monash is at the heart of a health and medical innovation ecosystem – extending to a commercial office in Boston, the world’s biotech capital – that is leveraging industry, education, research and innovation at scale.”

The research at Monash will be led by a distinguished team of scientific experts. Professor Angus Johnston, a leading expert in nanoparticle delivery biology and intracellular trafficking, will serve as Principal Investigator. He will be supported by Professor Colin Pouton, and Dr Moore Chen, who co-authored a seminal 2025 Nature Nanotechnology paper pioneering a new method of delivering mRNA to target cells.

“We’re excited to partner with CREATE to advance a shared vision for programmable medicines” said Professor Johnston. “Targeted delivery is one of the central challenges in realizing the promise of in vivo cell therapies and pairing our LNP technology with CREATE’s platform is a powerful step toward solving it.”

About CREATE Medicines
CREATE Medicines is a clinical-stage biotech pioneering in vivo CAR therapy. Its proprietary mRNA-LNP platform directly programs immune cells inside the body to deliver scalable, repeat-dose, off-the-shelf immunotherapies. With proven human validation, CREATE is advancing a pipeline of in vivo CAR therapies to transform outcomes in cancer and autoimmune diseases.

For more, visit createmedicines.com. Follow us on LinkedIn, X (Twitter), and Bluesky.

About Monash University
Monash University is Australia’s largest university with more than 80,000 students. In almost 70 years since its foundation, it has developed a reputation for world-leading research, quality teaching, inspiring innovation and translating game-changing research into impactful commercial and meaningful health outcomes. With four campuses in Australia and a global campus network covering Malaysia, China, India, Indonesia, and Italy, and the Boston Hub anchoring a footprint in the world’s leading biomedical cluster, Monash is Australia’s most international university.

For more, visit monash.edu.

About Monash Institute of Pharmaceutical Sciences
The Monash Institute of Pharmaceutical Sciences is the primary research hub of Monash University’s Faculty of Pharmacy and Pharmaceutical Sciences, which is ranked #2 globally in the QS World University Rankings by Subject. MIPS is comprised of over 400 scientists engaged in research in drug discovery, design, delivery and use.

For more, visit monash.edu/mips.

CREATE Business Development: partnering@createmedicines.com

CREATE Media Contact:
Jude Gorman / Kiki Torpey
Collected Strategies
CREATE-CS@collectedstrategies.com 

CREATE Investor Contact:
Brian Korb
Astr Partners
brian.korb@astrpartners.com
+1 (917) 653-5122

Monash Media Enquiries:
Philip Ritchie
Media and Communications Manager
philip.ritchie@monash.edu
+61 430 336 243

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SOURCE CREATE Medicines, Inc.

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HEVO Works with ORNL and BMW to Advance Evaluation of Next-Generation Wireless Charging Technology

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BROOKLYN, N.Y., Sept. 21, 2026 /PRNewswire/ — HEVO Inc., a New York-based leading developer and Tier 1 supplier of patented Rezonant™ wireless charging hardware and the Journey™ software platform, today announced its participation in a technology evaluation program involving Oak Ridge National Laboratory (ORNL) and BMW focused on advancing next-generation wireless charging technology.

The company HEVO is contributing wireless charging expertise, engineering support and circular coil topologies to assist BMW’s bench testing to evaluate compatibility with ORNL proprietary polyphase coil technology.

Recent industry interest in polyphase wireless charging has been driven by its potential to improve power density, efficiency and packaging while supporting future electric and autonomous vehicle applications. ORNL and BMW have publicly demonstrated advances in polyphase wireless charging systems that highlight the potential of the technology for next-generation mobility platforms.

“Wireless charging will be a foundational technology for the future of electric and autonomous transportation,” said Jeremy McCool, Founder and CEO of HEVO. “As an ORNL technology licensee, HEVO is pleased to support the continued evaluation of circular and polyphase wireless charging systems through technical analysis. We believe innovations that improve performance, efficiency and scalability can help accelerate the adoption of autonomous mobility, automated fleet operations and next-generation charging infrastructure. Our objective is to contribute practical experience from commercial wireless charging deployments while helping evaluate technologies that may support future electric vehicle ecosystems. We look forward to working alongside leading industry and research organizations as this effort progresses.”

The testing will build upon ORNL and BMW efforts to explore advanced wireless charging architectures capable of supporting future electric mobility platforms. HEVO believes wireless charging will play an increasingly important role in enabling automated vehicle operations, enhancing fleet utilization and supporting the continued evolution of electric transportation systems.

Additional Information
ORNL Polyphase Wireless Charging Technology
https://www.ornl.gov/technology/202305398

ORNL Research on Polyphase Wireless Power Transfer Systems
https://impact.ornl.gov/en/publications/modeling-and-analysis-of-a-polyphase-wireless-power-transfer-syst/

About HEVO Inc.
HEVO is a New York-based leading developer and Tier 1 supplier of patented Rezonant™ wireless charging hardware and the Journey™ software platform for electric and autonomous vehicles. HEVO’s UL certified and SAE qualified systems enable automated depot operations, resilient fleet charging and next-generation mobility platforms. Through its growing portfolio of intellectual property and commercial technologies, HEVO is advancing both stationary and dynamic wireless charging solutions for passenger vehicles, commercial fleets and autonomous mobility applications.

Learn more at HEVO.com, LinkedIn, YouTube, Instagram and X.

Forward-Looking Statements
This press release may contain forward-looking statements. All statements other than statements of historical fact are forward-looking statements and involve risks and uncertainties that may cause actual results to differ materially. These statements include, but are not limited to, expectations relating to research outcomes, future standards activities, interoperability evaluations, commercial adoption and industry acceptance of polyphase wireless charging technologies. Except as required by law, HEVO undertakes no obligation to update forward-looking statements.

Media and Commercial Inquiries
HEVO Press and Commercial Inquiries
 hello@hevo.com

HEVO Investment Inquiries
 invest@hevo.com

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SOURCE HEVO

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Schneider Electric advances energy and industrial intelligence for a more resilient future at Climate Week NYC 2026

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AI-enabled building optimization may reduce energy use by up to 22% in modeled scenariosPeer-reviewed research with Boston University finds the constraint on building modernization is not technology but the capacity to deploy itResearch shows cooling architecture and operating temperature can reduce water use by roughly half

NEW YORK, Sept. 21, 2026 /PRNewswire/ — Schneider Electric, a global energy technology leader, today outlined its presence at Climate Week NYC 2026, bringing new research on AI-enabled building efficiency, building modernization and data center water use, executive programming and forthcoming news on collective approaches to supply-chain decarbonization.  AI is driving increased energy demand, and when combined with data and domain expertise, it can also make energy systems more efficient and resilient. Across the week, Schneider Electric will show how energy and industrial intelligence can help organizations unlock capacity, strengthen resilience, and deliver measurable sustainability gains.

 Energy has become a board-level decision, and for most organizations the constraint is no longer ambition but execution. As an energy technology partner, Schneider Electric pairs energy and industrial intelligence with electrification, automation and advisory expertise to help close the time to power gap.

Beyond capacity and speed, this is also how sustainability delivers: making energy use more efficient, operations more resilient, and businesses more competitive, while creating the skills and jobs that bring more workers and communities into the new energy economy.

“Resilience is not something you buy once. It is what energy and industrial intelligence delivers when decisions get better,” said Pankaj Sharma, Executive Vice President, Software & Services at Schneider Electric. “What we are bringing to Climate Week NYC is the evidence: an AI layer that frees capacity inside a building, a cooling system that reuses the same fluid instead of drawing more. Energy and industrial intelligence applied to the infrastructure we already have, paired with the execution to deploy it.”

AI-enabled building optimization
Schneider Electric’s “AI for Climate: Quantifying the Energy and Carbon Impact of Building Optimization” white paper examines the effect of adding AI to existing building management systems. The analysis estimates energy savings of up to 22% compared with buildings without AI. It attributes 7.2% to 12.7% to the AI layer alone and estimates annual utility savings of $13,600 to $49,300 per building at the commercial rates used in the study.

Overcoming barriers to building modernization
The Schneider Electric Research Institute published “Modernizing the Built Environment,”  drawing on a four-study peer-reviewed program produced with Boston University’s Institute for Global Sustainability and a case study developed with the Bloomberg New Economy Energy Technology Coalition. Drawing on 95 catalogued barriers from 880 academic sources and 60 practitioner interviews, it finds that the constraint on building modernization is not technology but the capacity to deploy it, with retrofit cost premiums tracing to missing workforce, permitting and financing capacity rather than to equipment cost. Read together, the two papers make one argument: the efficiency is available today and closing the gap between what buildings can do and what they actually do is an institutional problem as much as a technical one.

Supporting responsible AI infrastructure growth
As AI drives growing demand for data center capacity, design choices can materially reduce the resource demands of the infrastructure supporting it. Schneider Electric today published “White Paper 220, Water Usage at AI Scale: Insights from a 100 MW Comparative Analysis.” The paper shows that on-site water consumption for cooling is strongly influenced by data center design choices, including heat-rejection technology, liquid-cooling architecture, and operating temperature.

In modeled 100 MW data center designs using adiabatic heat rejection, an optimized liquid-cooled AI architecture reduced annual on-site cooling water use by 48% in Dallas, from approximately 382,000 to 197,000 cubic meters, and by 53% in Paris, from approximately 108,000 to 51,000 cubic meters, compared with an air-cooled AI design. The analysis indicates that high-density AI capacity can be supported while materially reducing on-site water use for cooling.

Schneider Electric will also share further news during Climate Week on collective approaches to supply-chain decarbonization, building on its Energize and Catalyze programs.

New partnership with Lenovo brings decarbonization services to IT channel partners
Schneider Electric has also joined Lenovo 360 Circle, Lenovo’s global sustainability community, as a strategic ally, bringing the Schneider Electric Decarbonization Champion program to a network of more than 860 partners. Eligible partners gain carbon management tools to establish a Scope 1 and Scope 2 emissions baseline, training through Schneider Electric Sustainability School, and hands-on support from Schneider Electric Advisory Services specialists, including a remote site audit and a jointly developed decarbonization roadmap. It applies at ecosystem scale the approach Schneider Electric has taken in its own supply chain, where engaging its top 1,000 suppliers contributed to a 56% reduction in suppliers’ operational CO₂ emissions between 2021 and 2025.

Schneider Electric at Climate Week NYC

Sustainable Growth: The Implementation Imperative, Tuesday, Sept. 22, 2026, 9:30 a.m.–7 p.m. ET, Glasshouse Chelsea, 545 W. 25th St., including:New Vital Signs of Business Health, 9:30–10:30 a.m. ETEnergy Intelligence at Full Speed, 11:30 a.m.–1:00 p.m. ETFrom Targets to Execution: Closing the Clean Energy Gap, 2:00–3:00 p.m. ETAchieving District-Scale Decarbonization through Digital + Physical Integration, 2:00–3:30 p.m. ETFinancing Climate Action: The New Carbon Market Playbook for 2026, 3:15–3:45 p.m. ETUnlocking Decarbonization Across Fashion’s Global Supply Chain, 4:30–6:30 p.m. ET

Executives attending Climate Week NYC include:

Pankaj Sharma, EVP, Software & ServicesLena Henry, SVP, SE Advisory ServicesAndre Marino, SVP, Industrial Automation, North AmericaVanessa Miler-Fels, SVP, Global Supply Chain, Safety, Environment, Real Estate & SustainabilityAmit Chaturvedy, SVP, SE Ventures & PartnershipsSteve Carlini, Chief Advocate, Data Centers and AI, Energy Management BusinessMichele Hix, NAM VP, Strategic CustomersDave Rimkus, Head of Global Supply Chain Decarbonization, SE Advisory Services

Updates throughout Climate Week NYC will be shared through Schneider Electric’s global newsroom and U.S. newsroom.

Related resources

AI for Climate: Quantifying the Energy and Carbon Impact of Building OptimizationModernizing the Built Environment: Closing Institutional Gaps to Scale DecarbonizationWhite Paper 220, Water Usage at AI Scale: Insights from a 100 MW Comparative Analysis

About Schneider Electric

Schneider Electric is a global energy technology leader, driving efficiency and sustainability by electrifying, automating, and digitalizing industries, businesses, and homes. Its technologies enable buildings, data centers, factories, infrastructure, and grids to operate as open, interconnected ecosystems, enhancing performance, resilience, and sustainability. The portfolio includes intelligent devices, software-defined architectures, AI-powered systems, digital services, and expert advisory. With 160,000 employees and 1 million partners in over 100 countries, Schneider Electric is consistently ranked among the world’s most sustainable companies.

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SOURCE Schneider Electric

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Calamos Brings Award Winning SMID Cap PM Brandon Nelson to ETF Investors, Launches Calamos Timpani SMID Active Growth ETF (CTAG)

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CTAG brings Brandon Nelson, a 2024 Wall Street Journal Winners Circle PM, to the ETF wrapper for the first timeAcquired by Calamos in 2019, CTAG deploys a 30+ year time tested, disciplined stock selection strategy seeking to identify small- and mid-cap companies with “fundamental momentum” CTAG is the first actively managed mutual fund-to-ETF conversion to list on Texas Stock Exchange (TXSE)

CHICAGO, Sept. 21, 2026 /PRNewswire/ — John Koudounis, President and CEO of Calamos, a leader in liquid alternatives, today announced the launch of the Calamos Timpani Active SMID Growth ETF (CTAG) on the Texas Stock Exchange (TXSE). The ETF is a conversion of the Calamos Timpani SMID Growth Fund, a top-performing fund in the Morningstar Small Growth category.¹

“Our proven track record of active management in small- and mid-caps now extends to the ETF market,” said Koudounis. “We are thrilled to give ETF investors access to Brandon, one of the top discretionary active managers in the SMID universe. It is also an honor to be one of the first launches on the TXSE.”

Nelson was recognized as the only small cap manager in the Wall Street Journal’s 2024 Winners Circle, which annually identifies the Top 10 performers among active US stock managers. Since launching in 2019, the Calamos Timpani SMID Growth Mutual Fund has been a top-performer among peers in the Morningstar Small Growth category, healthily outperforming the Russell 2500 Growth Index over the last 1-, 3- and 5-year periods.²

“Our fundamental momentum investment style has proven itself over market cycles,” said Nelson, SVP and Senior Portfolio Manager. “Recent years have showcased the effectiveness of our growth investing process, security selection and strong selling discipline. We see significant and sustained upside for small- and mid-caps from here.”

“Demand for active ETFs is breaking records in 2026.³ Investors are asking for top-tier active management in a wrapper that’s liquid, transparent, and tax-efficient. After a historic run of large-cap outperformance, small-cap active ETFs represent one of the most exciting areas for investors seeking alpha and growth potential,” said Matt Kaufman, Head of ETFs. “This is exactly what we are delivering with this conversion.”

CTAG will be listed on the TXSE and will be the first active mutual fund-to-ETF conversion on the exchange. The conversion will enable Calamos to better differentiate this strategy from the Calamos Timpani Small Cap Growth Fund, which is managed by the same investment team under Nelson.

FUND DETAILS

Fund Name

Calamos Timpani Active SMID Growth ETF

Objective

Seeks to generate long-term capital appreciation through small- and mid-cap companies

Benchmark

Russell 2500® Growth Index 

Portfolio Management

Brandon Nelson

Exchange

TXSE

ETF Structure

Active

Underlyings

Small- and mid-cap growth stocks

Income Distribution

Annual

Unitary Fee

0.79 %

About Calamos

Calamos is a diversified global investment firm, headquartered in the Chicago metropolitan area, offering innovative investment strategies, including alternatives, multi-asset, convertible, fixed income, private credit, equity, Bitcoin and sustainable equity. With more than $52 billion in AUM, including more than $23 billion in liquid alternatives assets as of June 30, 2026, the firm offers strategies through ETFs, mutual funds, closed-end funds, interval funds, UCITS funds and separately managed portfolios. Clients include financial advisors, wealth management platforms, pension funds, foundations & endowments, and individuals, globally. For more information, visit us on LinkedIn, X (formerly Twitter), Instagram (@calamos_investments), or at www.calamos.com.

1 The Calamos Timpani SMID Growth Fund has outperformed both peers and its benchmark index (the Russell 2500 Growth Index) since its 2019 inception and in recent years. The fund more than doubled the performance of the average fund in the Morningstar Small Growth category in 2024 and 2025, as well as over the 5-year periods through August 31, 2026. The Institutional share class (CTIGX) of the fund was a top decile performer over the 3-year period ended August 31, 2026, and was ranked top quartile over the recent 1-year and 5-year periods ended August 31, 2026, according to Morningstar. Institutional share class total return and rankings in the Fund’s Morningstar category as of 8.31.26 are as follows: 26.40% return ranking 21st %ile for the 1-year period (111 / 533), 26.79% return ranking 3rd %ile for the 3-year period (13 / 521), 7.21% return ranking 14th %ile for the 5-year period (54 / 499), and 13.39% return ranking 13th %ile since inception (53 / 502). Returns longer than 1-year are annualized.

2 Percentile rankings in Morningstar’s Small Growth category, per Morningstar data, and comparisons against the Russell 2500 Growth Index are through 8.31.26 (26.40% to 15.32% over 1-yr; 26.79% to 14.13% over 3-years; and 7.21% to 3.51% over 5-years).

³ Active ETFs saw 35% of net inflows and $590.46 billion globally through July 31, 2026, according to ETFGI. “Year-to-date net inflows reached a record US$590.46 billion, exceeding the previous annual record pace of US$322.69 billion during the same period in 2025 and US$188.78 billion in 2024.”

On September 21, 2026, Calamos Timpani Active SMID Growth ETF (the “Fund”) acquired the assets and assumed the liabilities of the Calamos Timpani SMID Growth Fund (the “Predecessor Fund”) in a reorganization (the “Reorganization”). As a result of the Reorganization, performance prior to the Fund’s inception date reflects actual performance and expenses of the Class I shares of the Predecessor Fund, without any adjustments. The Fund has the same investment objective and substantially similar strategies as the Predecessor Fund. However, the Fund has a lower net expense ratio than each share class of the Predecessor Fund. As a result, the performance returns of the Fund for the periods shown would have been different than those of the Predecessor Fund. Had the Predecessor Fund been structured as an ETF, its performance may have differed. You can obtain current performance data by visiting www.Calamos.com.

The Fund’s (and Predecessor Fund’s) past performance (before and after taxes) is not necessarily an indication of how the Fund will perform in the future.

Average Annual Returns

Inception Date

1-Year

3-Year

5-Year

Since I Share Inception

Calamos Timpani SMID Growth Fund (I Shares at NAV)

7/31/2019

54.47

32.20

10.74

15.93

Russell 2500 Growth Index

32.94

16.40

4.98

10.95

Morningstar Small Growth Category

33.31

16.04

4.65

10.37

Data as of 6/30/2026.

Performance data quoted represents past performance, which is no guarantee of future results. Current performance may be lower or higher than the performance quoted. The principal value of an investment will fluctuate so that your shares, when sold, may be worth more or less than their original cost. Returns at NAV reflect the deduction of the Fund’s management fee and other expenses, which can be found on the next page. For the most recent Fund month end performance information, visit www.calamos.com or call 1-866-363-9219

The gross expense ratio for CTAG as of the prospectus dated 9/21/2026 is 0.79%

Before investing, carefully consider the Fund’s investment objectives, risks, charges and expenses. Please see the prospectus and summary prospectus containing this and other information which can be obtained by calling 1-866-363-9219. Read it carefully before investing.

An investment in the Fund is subject to risks, and you could lose money on your investment in the Fund. There can be no assurance that the Fund will achieve its investment objective. Your investment in the Fund is not a deposit in a bank and is not insured or guaranteed by the Federal Deposit Insurance Corporation (FDIC) or any other government agency. The risks associated with an investment in the Fund can increase during times of significant market volatility. The Fund also has specific principal risks, which are described below. More detailed information regarding these risks can be found in the Fund’s prospectus.

The principal risks of investing in the Calamos Timpani Active Growth Opportunities ETF include: American Depositary Receipts risk, authorized participant concentration risk, cash holdings risk, costs of buying and selling fund shares, currency risk, derivatives risk, equity securities risk, foreign securities risk, forward foreign currency contract risk, futures and forward contracts risk, growth stock risk, liquidity risk, market risk, portfolio selection risk, portfolio turnover risk, premium-discount risk, secondary market trading risk, sector risk, securities lending risk, small and mid-sized company stock risk, tax risk, and trading issues risk.

Equity Securities Risk — The securities markets are volatile, and the market prices of the Fund’s securities may decline generally. The price of equity securities fluctuates based on changes in a company’s financial condition and overall market and economic conditions. If the market prices of the securities owned by the Fund (i.e., the Fund’s long position) fall, the value of your investment in the Fund will decline.

Small and Mid-Sized Company Stock Risk — Small to mid-sized company stocks have historically been subject to greater investment risk than large company stocks. The prices of small to mid-sized company stocks tend to be more volatile and less liquid than large company stocks. Small and mid-sized companies may have no or relatively short operating histories, or be newly formed public companies. Some of these companies have aggressive capital structures, including high debt levels, or are involved in rapidly growing or changing industries and/or new technologies, which pose additional risks.

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SOURCE Calamos Investments

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