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Rice Biotech Launch Pad invents ‘living pharmacy’ designed to produce therapeutics inside the body

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Durable implant to enter clinic in 2027 has multiple applications and represents new therapeutic approach that lasts full year

HOUSTON, Oct. 2, 2026 /PRNewswire/ — Biologic medicines can be powerful treatments for many diseases, but their cost can limit access. According to the U.S. Food and Drug Administration, biologics account for just 5% of prescriptions but 51% of drug spending. Researchers at Rice University, with the support of the Rice Biotech Launch Pad, have developed an implantable “living pharmacy” using engineered protein producers (EPPs) that could one day deliver these medicines continuously for months or years from a single procedure.

According to the new study published in Science Advances titled “Once-yearly cell-based therapy for sustained and dose-tunable delivery of monoclonal antibodies,” engineered cells enclosed within a specially modified biomaterial continuously produced therapeutic monoclonal antibodies for one year across multiple preclinical models. The retrievable system also allowed researchers to stop treatment or adjust dosing by removing or replacing the implant.

The work addresses a key challenge for implantable cell therapies. The body’s foreign body response can cause inflammation and scar tissue to build up around an implant, restricting the movement of nutrients and therapeutic proteins and ultimately reducing cell survival and drug production.

“We have created an entirely new approach for the development and use of therapeutic antibodies,” said Robert S. Langer, co-founder of Duracyte and professor at the Massachusetts Institute of Technology. “By combining engineered cells, biomaterials and an implantable device, this approach has the potential to create a living pharmacy that provides long-lasting production of biologic medicines while maintaining a level of control that is important for therapeutic use.”

This platform is being developed by Duracyte, which is advancing the platform toward clinical development with the publication providing a foundation for further work on safety, biocompatibility, device design and therapeutic applications. The researchers also used human pharmacokinetic modeling to assess the potential for clinically relevant antibody levels and demonstrated a minimally invasive device designed to support dose adjustment and treatment cessation. Because EPPs can be engineered to produce different proteins, the platform could ultimately support a range of biologic medicines.

The platform was also designed to be adaptable across therapeutic targets. Researchers engineered the same human cell line to produce 13 different monoclonal antibodies spanning oncology, autoimmune disease and infectious disease, including ipilimumab, pembrolizumab, adalimumab, 3BNC117 and PGT121. The antibodies retained their intended biological activity, demonstrating the platform’s potential as a modular approach to mAb delivery.

“The potential of this platform is similar in some ways to the promise of reusable rockets for space travel which significantly reduced cost and time to manufacture,” said Omid Veiseh, professor of bioengineering at Rice University and corresponding author of the study. “Rather than repeatedly manufacturing and delivering a biologic from outside the body, EPPs could produce therapeutic proteins continuously inside the patient. If this approach can be successfully translated, it could offer a more efficient way to deliver biologics with the potential to reduce some of the costs associated with manufacturing and repeatedly administering these medicines.”

The potential economic impact comes at a time of growing concern over the cost and accessibility of biologic medicines. A recent report highlighted by The Wall Street Journal found that 90% of major biologic drugs expected to lose exclusivity over the next decade have no lower-cost competitors in development, underscoring the need for new approaches to how these medicines are produced and delivered.

The study was led by co-first authors Cody Fell, Anthony E. Davis and Shalini Pandey of the Department of Bioengineering at Rice in Houston. This work was supported by the Gates Foundation (INV-051204) and the Advanced Research Projects Agency-Health (AY1AX000003 and 1047648-490467).

This news release can be found online at news.rice.edu.

Follow Rice News and Media Relations via Twitter @RiceUNews.

Peer-reviewed paper:

Once-yearly cell-based therapy for sustained and dose-tunable delivery of monoclonal antibodies | Science Advances | DOI: 10.1126/sciadv.aej5440

Authors: Cody Fell, Anthony E Davis, Shalini Pandey, Michael T Guinn, Zeshi Wang, Jonathon DeBonis, Chancellor Smith, Nathan Brown, Danna Murungi, Yeonju Kim, Imaan Mohandessi, Patrick Bednarz, Amir Ardeshir, Erin M Haupt, Samuel I Cuevas, Christy L Lavine, Michael S Seaman, Oleg Igoshin, Ravi K Ghanta, Michael R Diehl, Omid Veiseh

About Rice:

Located on a 300-acre forested campus in Houston, Texas, Rice University is consistently ranked among the nation’s top 20 universities by U.S. News & World Report. Rice has highly respected schools of architecture, business, continuing studies, engineering and computing, humanities, music, natural sciences and social sciences and is home to the Baker Institute for Public Policy. Internationally, the university maintains the Rice Global Paris Center, a hub for innovative collaboration, research and inspired teaching located in the heart of Paris. With 4,776 undergraduates and 4,104 graduate students, Rice’s undergraduate student-to-faculty ratio is just under 6-to-1. Its residential college system builds close-knit communities and lifelong friendships, just one reason why Rice is ranked No. 1 for lots of race/class interaction and No. 7 for best-run colleges by the Princeton Review. Rice is also rated as a best value among private universities by the Wall Street Journal and is included on Forbes’ exclusive list of “New Ivies.”

If you do not wish to receive news releases from Rice University, reply to this email and write “unsubscribe” in the subject line. Office of News and Media Relations – MS 300, Rice University, 6100 Main St., Houston, TX 77005.

About the Rice Biotech Launch Pad:  

The Rice Biotech Launch Pad is a Houston-based accelerator focused on expediting the translation of Rice University’s health and medical technology discoveries into cures. This initiative is designed to help advance internally discovered platform technologies from concept to clinical studies and commercialization. The Rice Biotech Launch Pad will identify and support highly differentiated projects while driving the expansion of Houston as a world-class medical innovation ecosystem. The accelerator will bring together local researchers with a network of industry executives. For more information, please visit https://biotechlaunchpad.rice.edu/.

Media Contact:

Russo Partners
David Schull or Liz Phillips
(347) 956-7697
david.schull@russopartnersllc.com 
elizabeth.phillips@russopartnersllc.com

 

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Walden Media Group Named Newest Advertising and Growth Marketing Partner for Training Mate

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October 2, 2026

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Walden Media Group to lead paid media and growth strategy as the Australian born fitness brand expands its franchise footprint across the United States

AUSTIN, Texas, Oct. 2, 2026 /PRNewswire/ — Walden Media Group (WMG), a growth marketing agency specializing in franchise brands, today announced that it has been selected by Training Mate as the brand’s newest advertising and growth marketing partner.

Founded by former professional rugby player and celebrity trainer Luke Milton, Training Mate brings an Australian, team oriented approach to group fitness. Its high energy HIIT classes are built around community as much as results, a philosophy the brand sums up as “51% social, 49% fitness.” With Training Mate growing its franchise system nationally, the partnership positions WMG to support both corporate and franchisee growth.

Under the partnership, WMG will lead [paid search, paid social, local marketing, creative production, and performance reporting], with a focus on driving membership growth at existing studios and building strong launch momentum for new franchise locations.

“Training Mate has built something rare in fitness: a brand people genuinely want to belong to,” said Zachariah Walden, CEO of Walden Media Group. “Our job is to take that energy and turn it into consistent, measurable growth for every studio in the system. We’re proud to partner with the Training Mate team as they bring this community to more cities across the country.”

The partnership adds Training Mate to WMG’s growing portfolio of franchise clients across fitness, beauty, wellness, and healthcare. WMG’s franchise program combines standardized operating procedures and reporting with local market execution, giving franchisors brand consistency and franchisees clear visibility into performance.

About Training Mate
Born in Australia and refined in Los Angeles, Training Mate is a social fitness brand offering high energy, 45 minute HIIT workouts in a supportive, community first environment. The brand opened its first studio in West Hollywood in 2013 and is now expanding nationally through franchising.

About Walden Media Group
Walden Media Group (WMG) is a growth marketing company that helps franchise and enterprise brands drive measurable business outcomes. By integrating media, creative, data, and technology, WMG builds the growth engines that connect brand strategy to performance at every level of the organization.

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Franklin County Sheriff’s Office Facility Completes Annual Inspection with No Deficiencies Noted

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October 2, 2026

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Inspection highlights continued commitment to compliance, safety, sanitation and professional care

FRANKLIN COUNTY, Ohio, Oct. 2, 2026 /PRNewswire/ — Armor Health (ArmorHealthcare.com) is honored to partner with our client, the Franklin County Sheriff’s Office in Columbus, Ohio, and applauds their Franklin County Correctional Center II facility’s (Jackson Pike) successful completion of its annual inspection by the Bureau of Adult Detention from the Ohio Department of Rehabilitation and Correction, on September 8, 2026, with no deficiencies noted.

The inspection included a comprehensive review of facility operations, safety measures, sanitary conditions and compliance with applicable standards, including protocols related to health care delivery.

The outcome reflects the facility’s continued commitment to maintaining a safe, sanitary and professional environment while adhering to established regulatory requirements. The inspection also underscores the importance of ongoing preparedness, accountability and operational excellence in correctional settings.

“Successful inspections are the result of consistent preparation, teamwork and a commitment to doing things the right way every day,” said Tamara Taylor, Vice President of Client Relations at Armor Health. “We are proud of the work being done by the Franklin County team and the commitment they demonstrate to providing a safe environment and professional care for the individuals entrusted to their custody.”

For correctional facilities, maintaining compliance requires more than preparing for an annual inspection. It requires systems, processes and people that support consistent performance every day. The Franklin County inspection results demonstrate the facility’s focus on preparedness, compliance, and professional care.

About Armor Health- Armor Health is a leading provider of correctional healthcare services providing quality care to local correctional facilities across the country for more than 22 years. Every day, Armor provides evidence-based medical and mental health services revolutionizing the healthcare landscape utilizing its proprietary Insights Analytics, risk scoring, and predictive modeling. Powered by modern AI solutions from its partnership with Antidote-AI (Antidote-AI.com) our AI clinical tools, and our expert clinicians provide a laser focus on best-in-class interventions to deliver the right care, at the right time, in the right place to every patient we serve. 

Media Contact:
marketing@armorhealthcare.com

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Global Aluminum Die Casting Market to Reach USD 179.01 Bn. by 2034 as EV Growth, Lightweighting and Advanced Casting Technologies Accelerate, reports Maximize Market Research

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PUNE, India, Oct. 2, 2026 /PRNewswire/ — The Global Aluminum Die Casting Market was valued at USD 88.07 Billion in 2025 and is projected to grow at a CAGR of 8.2% from 2026 to 2034, reaching USD 179.01 Billion by 2034, according to a new analysis by Maximize Market Research.

Explore 140 market data tables and 75 figures across 310 pages, along with a detailed Table of Contents covering the Global Elastomers Market.

Global Aluminum Die Casting Market Size & Forecast

Market Size (Base Year 2025): USD 88.07 Billion
Forecast Market Size (2034): USD 179.01 Billion
CAGR (2026–2034): 8.2%
Base Year: 2025
Forecast Period: 2026–2034
Historical Period: 2020–2025

The Global Aluminum Die Casting Market is expanding as manufacturers increasingly turn to lightweight, precise, and high-strength aluminium components for automotive, electric vehicle, industrial, aerospace, and electronics applications. The process allows molten aluminium to be shaped into complex parts at high speed while maintaining dimensional accuracy and reducing material waste. Its importance is rising sharply in electric mobility, where battery housings, motor housings, transmission cases, chassis parts, and structural components must combine low weight with strength and thermal performance.

The market is also being reshaped by automation, giga-casting, AI-driven quality control, advanced aluminium alloys, and recycled material use. Manufacturers are investing in larger casting systems, smarter production lines, and integrated structural components to improve efficiency and reduce part counts. Asia Pacific remains the leading regional market, supported by strong automotive and EV production across China, India, Japan, and South Korea. Recent investments by Nemak, Jaya Hind Industries, and Endurance Technologies show how capacity expansion and e-mobility demand are accelerating the next phase of market growth.

Get Full PDF Sample Copy of Report: (Including Full TOC, List of Tables & Figures, Chart) @ https://www.maximizemarketresearch.com/request-sample/133357/ 

The Global Aluminum Die Casting Market is moving beyond conventional component manufacturing toward larger, lighter, and more integrated vehicle structures. Electric mobility, automation, advanced casting technologies, and recycled aluminium are changing how manufacturers design and produce critical components. Companies that can combine scale, precision, efficiency, and sustainable production are likely to shape the market through 2034.

Aluminum Die Casting Market Growth Drivers, Opportunities & Key Highlights

The Global Aluminum Die Casting Market is gaining momentum as automakers increasingly rely on lightweight aluminium components to improve vehicle efficiency, extend EV range, and meet stricter emission standards. Demand is rising for battery housings, motor housings, transmission cases, chassis parts, and integrated structural components. Global electric car sales exceeded 20 million units in 2025, while China produced nearly 16 million electric cars, representing almost 75% of global EV production, creating a strong foundation for aluminium die-cast component demand.

A second growth opportunity is developing around high-pressure die casting, giga-casting, automation, IoT-based monitoring, and AI-driven quality control. Manufacturers are investing in larger and smarter casting operations that can reduce defects, lower material waste, and produce complex components at scale. Recent developments reinforce this trend: Nemak completed a USD 336 million acquisition of GF Casting Solutions’ automotive business, while Jaya Hind Industries announced a ₹600 crore investment to strengthen its HPDC and gravity die-casting capabilities.

Key Market Highlights

USD 88.07 Billion: Global market size in 2025.USD 179.01 Billion: Projected market size by 2034.8.2% CAGR: Expected growth during 2026–2034.20+ million EVs: Global electric car sales surpassed this level in 2025.~75%: China’s share of global EV production in 2025, with nearly 16 million electric cars produced.USD 336 million: Value of Nemak’s 2026 acquisition of GF Casting Solutions’ automotive business.₹600 crore: Jaya Hind Industries’ announced investment to expand HPDC and gravity die-casting capabilities.900–1,100 tonnes/month: Initial and scalable casting capacity at Endurance Technologies’ new Maharashtra facility.

India Aluminum Die Casting Market Gains Momentum Through Capacity Expansion and EV Manufacturing

India is emerging as an important growth center for aluminum die casting as automotive and electric-vehicle production expands. In August 2026, Jaya Hind Industries announced a ₹600 crore phased investment to strengthen its high-pressure and gravity die-casting capabilities, while Endurance Technologies added new aluminum die-casting capacity at its Mindewadi, Pune facility and later began commercial production at a new Chhatrapati Sambhajinagar plant with 900 metric tonnes of monthly capacity, scalable to 1,100 tonnes. These investments highlight India’s growing role in precision aluminum components, EV structures, powertrain parts, and localized automotive manufacturing.

Get Insightful Data on Regions, Market Segments, Customer Landscape, and Top Companies (Charts, Tables, Figures and More) https://www.maximizemarketresearch.com/request-sample/133357/ 

Global Aluminum Die Casting Market Segmentation Analysis

The Global Aluminum Die Casting Market is segmented by Process, Application, and Region. By Process, Pressure Die Casting holds the dominant position because it can produce large volumes of complex, dimensionally accurate components with tight tolerances and smooth finishes. Its speed, repeatability, and lower need for post-machining make it especially valuable in automotive, aerospace, and electronics manufacturing. Vacuum, squeeze, and gravity die casting also serve applications that require specific structural and quality characteristics.

By Application, Automotive and Transportation leads the market, driven by demand for lightweight and high-strength components that improve fuel efficiency, reduce emissions, and support electric mobility. Aluminum die casting is widely used in engine blocks, transmission housings, battery enclosures, motor housings, chassis parts, and structural reinforcements. Industrial machinery, building & construction, electronics & consumer goods, aerospace, and healthcare also contribute to market demand.

By Region, Asia Pacific remains the leading market, supported by strong automotive and EV production across China, India, Japan, and South Korea. The region’s investment in advanced manufacturing, high-pressure die casting, and lightweight vehicle components continues to strengthen its market position through 2034.

Asia Pacific Leads the Aluminum Die Casting Market as EV and Lightweight Manufacturing Accelerate

Asia Pacific remains the center of the Global Aluminum Die Casting Market, supported by its deep automotive manufacturing base and rapid shift toward electric mobility. China, India, Japan, and South Korea are investing heavily in advanced production, while growing demand for battery housings, motor housings, transmission cases, and structural parts is pushing die casting into a more important role within vehicle design. China’s scale in EV production gives the region added momentum, while India is steadily strengthening its position through new capacity and localized manufacturing.

North America and Europe continue to move forward through a different route, with greater emphasis on lightweight vehicle structures, giga-casting, recycled aluminium, automation, and more integrated components. The United States remains important for EV and advanced manufacturing investment, while Germany, Italy, France, and Spain continue to support demand through strong automotive industries and tighter sustainability goals. South America and the Middle East & Africa are developing more gradually as industrialization, infrastructure investment, and local manufacturing capabilities improve.

Global Elastomers Market Competitive Landscape

The Global Elastomers Market is highly competitive, with leading companies focusing on specialty formulations, sustainable materials, capacity expansion, and application-specific innovation. Dow is investing around USD 100 million through 2027 to expand specialty silicone manufacturing and innovation capabilities across the U.S., China, and Japan. BASF has started commercial production of flame-retardant Elastollan® TPU in Shanghai for industrial automation, robotics, and EV charging applications, while LANXESS introduced Vulkanox 4060 as a new anti-aging solution for tire applications.

Other companies are strengthening regional manufacturing and supply capabilities. Getzner Werkstoffe opened a new polyurethane elastomer facility in Baramati, India, while SaarGummi expanded its Chennai operations for EPDM and TPV automotive sealing systems. Across the market, competition is increasingly centered on high-performance TPEs, recyclable grades, bio-based feedstocks, low-emission formulations, EV applications, and customized elastomer solutions.

Immediate Delivery Available | Buy this Research Report (Insights, Charts, Tables, Figures and More) https://www.maximizemarketresearch.com/checkout/133357/ 

Aluminium Die Casting Market, Key Players

North America

Nemak S.A.B. de C.V.Pace IndustriesDynacast InternationalMartinrea International Inc.Gibbs Die CastingMadison-Kipp CorporationConsolidated Metco, Inc.Ryobi Die Casting USA, Inc.Meridian Lightweight Technologies Inc.Shiloh Industries, Inc.Bocar GroupAludyneAlcast Technologies Ltd.PHB Corp.Walbro LLCApex Aluminum Die Casting Co., Inc.Kinetic Die Casting Company, Inc.Koch Enterprises, Inc.

Europe

GF Casting Solutions Rheinmetall AG FAIST Group Martinrea Honsel Germany GmbH Handtmann Group Bühler Group Zollern GmbH & Co. KG CIE Automotive S.A. BUVO Castings B.V. Bharat Forge Aluminiumtechnik GmbH Kemlows Diecasting Products Ltd. Georg Fischer Ltd. Italpresse Gauss Sundaram Clayton Ltd. Sika Technology Limited

Asia-Pacific

Endurance Technologies Limited Ryobi Limited Rockman Industries Limited Ahresty Corporation Ningbo Tuopu Group Co., Ltd. Guangdong Hongtu Technology Co., Ltd. Chongqing CHAL Precision Aluminium Co., Ltd. IKD Co., Ltd. Minda Corporation Ltd. Sandhar Technologies Limited Sundaram-Clayton Limited Engtek Group KPSNC Co., Ltd. UBE Corporation / UBE Machinery Shibaura Machine Co., Ltd. Toshiba Machine / Toshiba Machine Co., Ltd. Alcoa Corporation

Access Full Summary: https://www.maximizemarketresearch.com/market-report/aluminum-die-casting-market/133357/ 

Analyst Perspective

Analyst highlights that the Global Aluminum Die Casting Market is gaining strategic importance as automakers push for lighter vehicles, longer EV range, and more integrated structural designs. Automotive and transportation remain at the center of demand, while aerospace, industrial machinery, electronics, and construction continue to expand the market’s reach. As high-pressure die casting, giga-casting, automation, recycled aluminium, and AI-driven quality control become more prominent, Asia Pacific is expected to remain the key production and demand hub. Companies that combine scale, precision, technology, and sustainable manufacturing are likely to shape the market through 2034.

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About Maximize Market Research – Global Aluminum Die Casting Market

Maximize Market Research is a global market research and business consulting firm providing data-driven insights across chemicals & materials, automotive, aerospace, electronics, industrial manufacturing, and construction sectors. Its Global Aluminum Die Casting Market research covers pressure, vacuum, squeeze, and gravity die casting along with automotive and transportation, industrial machinery, aerospace, electronics, and other major applications. The report also examines EV components, lightweight structures, giga-casting, automation, recycled aluminium, regional demand, competitive strategies, and recent industry developments, helping businesses understand market shifts and identify growth opportunities through 2034.

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MMR Statistics is a part of Maximize Market Research, developed to provide quick access to market size, industry data, forecasts, trends, and statistical insights across a wide range of sectors. It presents research data in multiple formats, making it easier for businesses, analysts, and decision-makers to use market intelligence for presentations, strategy, benchmarking, and business planning.

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Stellar Market Research is a strategic partner of Maximize Market Research, providing global and region-wise market research reports across multiple industries. Its research focuses on market trends, competitive developments, regional opportunities, industry dynamics, and growth outlooks, complementing Maximize Market Research with broader market coverage and region-specific business intelligence.

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MAXIMIZE MARKET RESEARCH PVT. LTD.
+91 96073 65656
Email: sales@maximizemarketresearch.com   
Visit Our Web Site: https://www.maximizemarketresearch.com/   

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