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10x Genomics Launches 5,000-Plex Gene Panel for Xenium

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 New Xenium Prime 5K Pan-Tissue and Pathways panel increases plex by an order of magnitude and delivers industry-leading speed and throughput

PLEASANTON, Calif., May 29, 2024 /PRNewswire/ — 10x Genomics, Inc. (Nasdaq: TXG), a leader in single cell and spatial biology, announced today the launch of its Xenium Prime 5K Pan-Tissue and Pathways panel. The new assay features an enhanced chemistry to increase plex by an order of magnitude while delivering excellent per-gene sensitivity, improved specificity and spatial fidelity, integrated multimodal cell segmentation, and industry-leading speed and throughput.

“Seeing the Xenium Prime 5K data reminded me of the excitement I experienced when I saw single cell RNA-seq data for the first time,” said Dr. Kevin Wei, M.D., Ph.D., Assistant Professor of Medicine at Harvard Medical School. “Now, we can identify relevant molecular pathways in human diseases and explore new biological hypotheses, all from one glass slide.”

The high-plex Xenium Prime 5K assay enables a new level of exploration for pathways, biomarkers, ligand-receptor pairings and cell-cell interactions. Key features include:

Highest plex Xenium panel for comprehensive profiling of cell types and states and cell signaling pathways across multiple tissue and disease types.Excellent data quality to unlock mechanisms of disease, therapeutics and cell behavior. The Xenium Prime 5K assay is optimized for performance and paired with 10x Genomics’ advanced multimodal cell segmentation, enabling high sensitivity, specificity and spatial fidelity.Rapid turnaround time with easy, tissue-agnostic workflows. 10x Genomics’ industry-leading throughput enables researchers to analyze up to 472 mm² of tissue in six days or less.Easily customizable with up to 100 additional genes to capture customers’ specific research needs.Rigorously designed and developed using single cell RNA-seq data from dozens of different organs and tissues, gene expression profiles from hundreds of cell types and a screen of more than 750,000 peer-reviewed publications to pinpoint highly cited biomarkers.

“We successfully launched Xenium with a broad menu of curated and highly customizable gene panels so customers could target specific biology important for their research,” said Michael Schnall-Levin, Founding Scientist and Chief Technology Officer at 10x Genomics. “With the launch of our 5K gene panel, researchers can now also use Xenium for spatial exploration, enabling more biology and more breakthroughs. This assay is yet another example of how we put our innovation engine to work for our customers and build best-in-class products that deliver best-in-class results.”

The Xenium Prime 5K assay, optimized for human and mouse species, is now available for preorder and is expected to ship next month.

About 10x Genomics
10x Genomics is a life science technology company building products to accelerate the mastery of biology and advance human health. Our integrated solutions include instruments, consumables and software for single cell and spatial biology, which help academic and translational researchers and biopharmaceutical companies understand biological systems at a resolution and scale that matches the complexity of biology. Our products are behind breakthroughs in oncology, immunology, neuroscience and more, fueling powerful discoveries that are transforming the world’s understanding of health and disease. To learn more, visit 10xgenomics.com or connect with us on LinkedIn or X (Twitter).

Forward Looking Statements
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 as contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which fall under the “safe harbor” provisions of those sections. All statements, other than statements of historical facts, may be forward-looking statements. Forward-looking statements generally can be identified by the use of forward-looking terminology such as “may,” “might,” “will,” “should,” “expect,” “plan,” “anticipate,” “could,” “intend,” “target,” “project,” “contemplate,” “believe,” “estimate,” “predict,” “potential” or “continue” or variations of them or similar terminology, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include statements regarding 10x Genomics, Inc.’s (“10x Genomics”) product launches, performance, configuration, capabilities, adoption and pipeline. These statements are based on management’s current expectations, forecasts, beliefs, assumptions and information currently available to management, and actual outcomes and results could differ materially from these statements due to a number of factors. Other risks and uncertainties that could affect 10x Genomics’ financial and operating results and cause actual results to differ materially from those indicated by the forward-looking statements made in this press release include those discussed under the captions “Risk Factors” and “Management’s Discussion and Analysis of Financial Condition and Results of Operations” and elsewhere in the documents 10x Genomics files with the Securities and Exchange Commission (the “SEC”) from time to time. Although 10x Genomics believes that the expectations reflected in the forward-looking statements are reasonable, it cannot provide any assurance that these expectations will prove to be correct nor can it guarantee that the future results, levels of activity, performance and events and circumstances reflected in the forward-looking statements will be achieved or occur. The forward-looking statements in this press release are based on information available to 10x Genomics as of the date hereof, and 10x Genomics disclaims any obligation to update any forward-looking statements provided to reflect any change in its expectations or any change in events, conditions or circumstances on which any such statement is based, except as required by law. These forward-looking statements should not be relied upon as representing 10x Genomics’ views as of any date subsequent to the date of this press release.

Disclosure Information
10x Genomics uses filings with the Securities and Exchange Commission, our website (www.10xgenomics.com), press releases, public conference calls, public webcasts and our social media accounts as means of disclosing material non-public information and for complying with our disclosure obligations under Regulation FD.

Contacts
Investors: investors@10xgenomics.com
Media: media@10xgenomics.com

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SOURCE 10x Genomics, Inc

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Sequel Brands Launches MOVE Powered by SEQUELai, the Company’s Sixth Brand and First Digital Wellness Platform

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MOVE closes the gap between knowing what to do and actually doing it with an AI coach designed for everyone – not just people who already exercise.

NEWPORT BEACH, Calif., July 20, 2026 /PRNewswire/ — Sequel Brands today announced the launch of MOVE powered by SEQUELai, the company’s sixth brand and first digital wellness platform. Joining a portfolio that includes Pilates Addiction, BODY20, iFlex Stretch Studios, Beem Light Sauna, and Ultimate Longevity Center, MOVE is available now on iOS and Android for $5/month or $25/year – a price point designed to make personalized wellness more accessible, regardless of fitness background. The platform combines AI-powered coaching, personalized workouts, recovery guidance, nutrition support, and daily accountability to help users build healthier routines that last.

Despite widespread awareness of healthy living, millions of Americans still struggle to consistently put healthy habits into practice. According to the CDC, fewer than half of U.S. adults meet federal guidelines for aerobic physical activity. MOVE was built to close that gap by making healthy movement simple, achievable, and sustainable – especially for those who don’t consider themselves “fitness people.”

Extending Sequel’s Mission Beyond the Studio

For Sequel Founder and CEO Anthony Geisler, who has spent his career building and scaling some of the industry’s most recognizable studio brands – from Club Pilates and Pure Barre to Sequel’s portfolio today – MOVE is the culmination of a belief he has championed for years: movement is the foundation of better health. Through industry stages, interviews, and podcasts – including his keynote at last year’s Athletech News Innovation Summit – Geisler has consistently argued that America’s health challenge isn’t a lack of information; it’s turning knowledge into consistent action.

“Movement is medicine – it’s the catalyst for all other health habits. Get a workout in, and a bowl of ice cream stops sounding like a good idea. Skip it, and the rest of the day tends to follow,” said Geisler. “The goal with MOVE is simple: more people moving more often, in more accessible ways.”

SmartCoach: AI That Adapts as You Do

At the heart of MOVE is SmartCoach, an AI-powered wellness coach that creates a personalized plan based on each member’s goals, fitness level, and schedule – then continuously learns and adapts as they progress. While most wellness apps are built for people who already exercise regularly, SmartCoach is designed for the millions who don’t, meeting users where they are and helping them build sustainable habits over time. Beyond personalized coaching, MOVE delivers programming across strength, cardio, mobility, recovery, sleep, meditation, nutrition, mental wellness, women’s health, GLP-1 companion support, and clinically informed musculoskeletal (MSK) recovery.

The platform will continue to evolve with new AI-powered experiences. Upcoming features include MePod, a personalized weekly podcast that recaps each member’s progress and prepares them for the week ahead, and Daily Recommendations, a dynamic workout feed that updates in real time based on how each person is actually training. Wearables integration follows, connecting with fitness trackers and health apps members are already using.

AI-Powered Innovation Across the Sequel Ecosystem

MOVE marks the beginning of Sequel’s broader AI strategy. The company is already developing the next generation of AI-powered member experiences designed to help people build healthier daily habits that drive long-term health and longevity, while giving franchisees new ways to improve retention, deepen member relationships, and drive more visits to their studios.

“Technology should make healthy living easier, not more overwhelming,” said Alex Isaly, Sequel Brands’ President of Platform and AI Strategy. “MOVE meets people where they are, with coaching that adapts as they do. This is the first step in Sequel’s broader AI strategy to turn education into execution – creating better experiences for members and unlocking new ways to support our growing wellness ecosystem.”

The MOVE Smarter, Live Brighter Challenge

To celebrate the launch, Sequel is introducing the MOVE Smarter, Live Brighter Challenge, starting July 20. Designed for every fitness level, participants complete four sessions each week – including walking, strength, mobility, and sleep – for a total of 16 guided sessions, while a live in-app tracker measures the community’s total minutes of movement in real time. No gym, equipment, or fitness background is required to get started.

To join the challenge, download MOVE powered by SEQUELai, available now on iOS and Android, or visit sequelbrands.com/move-challenge.

ABOUT SEQUEL BRANDS
Sequel Brands is a next-generation fitness franchisor redefining the future of movement, recovery, wellness, and longevity. With an experienced leadership team and a portfolio of high-growth concepts – including Pilates Addiction, iFlex Stretch Studios, Beem Light Sauna, BODY20, Ultimate Longevity Center, and MOVE Powered by SEQUELai – Sequel delivers a scalable platform built for lasting success, cultural impact, and real results in how people move, recover, and optimize their longevity. For more information, visit sequelbrands.com

MEDIA CONTACTS
Sequel Brands Communications
E: communications@sequelbrands.com

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SOURCE Sequel Brands

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B&R Technology Merger Corp. Announces Pricing of $325 Million Initial Public Offering

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NEW YORK, July 20, 2026 /PRNewswire/ — B&R Technology Merger Corp. (the “Company”) announced the pricing of its initial public offering of 32,500,000 units at $10.00 per unit. The units will be listed on the Nasdaq Global Market (“Nasdaq”) under the symbol “BRTMU” commencing on July 21, 2026. Each unit consists of one Class A ordinary share of the Company and one-third of one warrant, each whole warrant entitling the holder thereof to purchase one Class A ordinary share of the Company at an exercise price of $11.50 per share. Once the securities constituting the units begin separate trading, the Company expects that the Class A ordinary shares and warrants will be listed on Nasdaq under the symbols ” BRTM” and ” BRTMW,” respectively.

The Company was formed for the purpose of effecting a merger, amalgamation, share exchange, asset acquisition, share purchase, reorganization or similar business combination with one or more businesses. It may pursue an initial business combination target in any business or industry.

Citigroup Global Markets Inc. (“Citigroup”) is acting as sole bookrunner and representative of the underwriters. The Company has granted the underwriters a 45-day option to purchase up to 4,875,000 additional units at the initial public offering price to cover over-allotments, if any.

This offering will only be made by means of a prospectus. Copies of the preliminary prospectus relating to the offering and final prospectus, when available, may be obtained from Citigroup, c/o Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, New York 11717 or by telephone at (800) 831-9146.

A registration statement relating to these securities has been declared effective by the U.S. Securities and Exchange Commission (the “SEC”). This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of these securities in any State or jurisdiction in which such an offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such State or jurisdiction.

FORWARD-LOOKING STATEMENTS

This press release contains statements that constitute “forward-looking statements,” including with respect to the proposed initial public offering and the anticipated use of the net proceeds. No assurance can be given that the offering discussed above will be completed on the terms described, or at all, or that the net proceeds of the offering will be used as indicated. Forward-looking statements are subject to numerous conditions, many of which are beyond the control of the Company, including those set forth in the Risk Factors section of the Company’s registration statement and preliminary prospectus for the Company’s offering filed with the SEC. Copies are available on the SEC’s website, www.sec.gov. The Company undertakes no obligation to update these statements for revisions or changes after the date of this release, except as required by law.

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SOURCE B&R Technology Merger Corp.

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Paris-Planet Is Back with a Fresh New Way to Explore Paris

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MONTREAL, July 20, 2026 /PRNewswire/ — Planning a trip to Paris just got a little easier.

Paris-Planet has officially relaunched with a completely redesigned website that helps travelers discover and book some of Paris’s best museums, attractions, tours, and local experiences in one place.

The new site was built for people who want to spend less time jumping between dozens of websites and more time getting excited about their trip. Whether it’s your first visit to Paris or your fifth, Paris-Planet brings together the experiences that make the city unforgettable.

“We wanted to build the kind of website we would actually use ourselves,” said Chaz Desousa, founder of Paris-Planet. “There are so many incredible things to see in Paris, but planning a trip can quickly become overwhelming. Our goal was to make discovering and booking experiences simple, inspiring, and enjoyable.”

Visitors can browse everything from famous landmarks and museums to food tours, river cruises, walking tours, family activities, and seasonal events. Along with tickets and experiences, the site also features destination guides, travel tips, and ideas for making the most of every day in Paris.

The relaunch also includes a faster website, improved navigation, and a mobile-friendly design, making it easy for travelers to plan before they leave home or while they’re already exploring the city.

Activity provider can sign up here to Sell Paris Tours & Tickets Online

Paris remains one of the world’s most visited destinations, welcoming millions of visitors every year. Paris-Planet was created to help those travelers spend less time searching and more time experiencing everything the city has to offer.

About Paris-Planet

Paris-Planet is an online travel guide and booking platform focused exclusively on Paris. The website helps visitors discover museums, attractions, tours, activities, and unique local experiences while making trip planning simple and enjoyable.

For more information, visit www.paris-planet.com.

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SOURCE Paris-Planet

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