Technology

Menarini’s cell based non-invasive prenatal technology demonstrates high resolution detection of fetal genomic abnormalities from a simple maternal blood draw

Published

2 years ago

July 2, 2024

Data presented at the 2024 FMF (Fetal Medicine Foundation) World Congress in Lisbon, Portugal shows the potential for an automated system to deliver genomic profiles of fetal cells that is highly concordant with the genomic analysis obtained from invasive procedures. Results of a large clinical validation study show that Menarini Silicon Biosystems’ fetal cell based noninvasive prenatal screening (NIPT) technology can accurately detect both fetal genome-wide pathogenic copy number variants greater than 600Kb in size and the commonly screened trisomy conditions.

BOLOGNA, Italy and HUNTINGDON VALLEY, Pa., July 2, 2024 /PRNewswire/ –The Reproductive Precision Medicine Unit of Menarini Silicon Biosystems (MSB) presented last week, at the 21st World Congress of the Fetal Medicine Foundation meeting in Lisbon, Portugal, results of a large multicenter study describing their next generation non-invasive prenatal testing technology using fetal cells isolated from maternal blood. The genomic analysis of these fetal cells showed a high concordance with the analysis of fetal cells obtained from invasive diagnostic procedures. Moreover, MSB’s cell-based test, under development, demonstrated its potential validity for screening genomic conditions not easily found with currently available, state of the art, non-invasive screening technologies based on cell-free DNA (cfDNA) analysis.

This large study, which enrolled over 1,000 women, was centered on isolating individual fetal (trophoblast) cells from maternal blood and analyzing them for both common trisomic conditions and genome-wide microdeletions and microduplications, called pathogenic copy number variants (pCNVs), that account for significant perinatal morbidity and mortality. The results presented showed that MSB’s fetal cell based NIPT could deliver information beyond core “common” trisomies detected by standard non-invasive cfDNA analysis, as well as detect with a high level of accuracy and granularity genome-wide microdeletions and microduplications down to a size of at least 600Kb. The cell-based test was compared with chromosomal microarray analysis (CMA) and karyotype from chorionic villus sampling (CVS) or amniocentesis, the clinical gold – standard fetal diagnostic methodologies to detect genomic chromosomal abnormalities in the prenatal setting.

According to Professor Jon Hyett, Head of Maternal and Fetal Medicine at Liverpool Hospital and Professor of Obstetrics and Gynaecology at Western Sydney University, who looks after pregnancies that have a high risk of complication – either for the mother, or for the fetus: “This data is exciting because it shows the potential to deliver clinically relevant and actionable information about fetal genomic abnormalities at higher resolution and accuracy than existing screening tests and at an early gestational age when almost no pCNVs are currently detected.” Menarini’s new study thereby opens the door to a whole new paradigm in prenatal screening.

For Thomas Musci, MD, Chief Medical Officer, Head of Menarini Silicon Biosystems’ Reproductive Precision Medicine Business Unit, who presented the results of the study, “Isolating intact fetal cells from maternal blood for prenatal screening has long been perceived as an extremely challenging goal. Our highly automated system for the isolation and single–cell analysis of circulating extravillous trophoblasts (cEVTs) supports the feasibility of a cell–based NIPT for fetal genomic profiling that can lead to more informed decision-making at all levels.”

Menarini has been actively investing to advance single cell analysis and sequencing in the field of reproductive care. For Fabio Piazzalunga, President of Menarini Silicon Biosystems, “The results of this study, which confirmed the potential ability of our cell based NIPT to identify fetal abnormalities with high sensitivity, accuracy, and specificity, show the potential of Menarini to significantly impact women’s health. Our continuous commitment and efforts to advance our scientific findings in this field aim to provide, in the future, a potentially revolutionary solution that brings more information to women and their doctors”. These new activities fully support the company’s vision to become a leader in minimally invasive cell-based applications that can allow for easier, faster, and more precise diagnostic and therapeutic approaches in multiple therapeutic areas.

About Menarini Silicon Biosystems (MSB)

MSB offers unique rare cell technologies and solutions that provide clinical researchers with access to unparalleled resolution in the study of cells and their molecular characterization.

Menarini Silicon Biosystems, based in Castel Maggiore (Bologna, Italy), and Huntingdon Valley, PA., U.S., is a wholly owned subsidiary of the Menarini Group, a multinational pharmaceutical, biotechnology and diagnostics company headquartered in Florence, Italy, with more than 17,000 employees in 140 countries.

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Contact:
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Linda PAVY
lipavy@pavyconsulting.com

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Technology

Neptune Robotics Invests US$12mn in New Singapore Factory to Drive Five-Fold Increase in Autonomous Ship Hull Cleanings

Published

51 minutes ago

April 20, 2026

Move to capture a larger share of Singapore’s hull cleanings at berth and anchorage
New R&D operations enhances cutting-edge robotics and AI capabilities

SINGAPORE, April 20, 2026 /PRNewswire/ — Neptune Robotics (“Neptune”), a pioneer in AI-powered robotic hull cleaning services with a presence in 61 ports across Singapore and China, today announced a major manufacturing and R&D expansion in Singapore. This is part of the company’s continuing ambition to tackle biofouling, one of the shipping industry’s costliest issues with significant environmental impact.

On the back of a US$52 million Series B round led by Granite Asia in September 2025, the new facility will accelerate Neptune’s mission to slash maritime carbon emissions and fuel wastage through automated hull maintenance.

“Our investment in Singapore is a strategic milestone that will enhance our service provision to clients and position us to meet their current and future needs,” said Elizabeth Chan, Co-Founder and CEO of Neptune Robotics. “With operators facing mounting fuel cost and emissions pressures, we’re scaling autonomous hull cleaning to help mitigate these issues and empower our clients to run more sustainable shipping operations.”

A growing number of shipowners are realizing the benefits of Neptune’s solutions. Biofouling — the buildup of marine growth on hulls — can increase ship greenhouse gas emissions by up to 25-30%[1] depending on vessel characteristics and conditions. Neptune’s AI robots remove this growth without damaging hull coatings, providing an immediate ROI for shipowners facing volatile energy markets and evolving sustainability regulations.

The new facility will bring a number of benefits including:

Increased capacity: By the end of 2026, Neptune will increase its local autonomous cleaning capacity by 400% with plans to reach 60 daily hulls by 2027.Advancing AI and robotics: The new facilities in Singapore will house dedicated R&D operations to advance the company’s proprietary computer vision and machine learning capabilities. This will ensure robots can operate 24/7 in challenging conditions including extreme weather, strong currents and low-visibility water.

With a global network now covering 61 strategic ports across Singapore and China, Neptune is scaling AI-driven hull maintenance to the heart of global trade. The company now services 70% of Asia’s primary shipping lanes, providing standardized, robotic hull cleaning at more than half of the world’s international merchant stops.

Since entering the Singapore market in 2024, Neptune has seen significant growth even as the local competitive landscape has thinned. By automating the hull cleaning process, Neptune eliminates the need for human divers in dangerous environments while ensuring vessels remain fuel efficient at sea.

Neptune will be exhibiting at Booth D19 during Singapore Maritime Week (SMW), April 20–24, 2026.

– ENDS –

About Neptune Robotics

Neptune Robotics is a technology company specializing in robotics-driven vessel cleaning and energy efficiency optimization.

Its robotic system can clean full draft capesize vessels within 24 hours, counter 4-knot currents, and operate day and night in both clear and murky waters. With coverage across 61 ports in Singapore and China — representing around 70% of major trade routes — Neptune supports shipowners at scale.

Neptune’s services are trusted by the world’s top five bulk carrier and container ship fleets. Its approach has earned endorsement from a leading silicone paint manufacturer for protecting hull coatings. Capable of cleaning all vessel types, Neptune helps clients cut fuel use, lower emissions, and advance their 2050 net-zero goals.

In September 2025, Neptune raised US$52 million in Series B funding led by Granite Asia to drive R&D, new robotic systems, and global expansion.

Company website: Neptune Robotics | ROV Underwater Hull Cleaning

[1] https://shipandbunker.com/news/emea/266832-imo-publishes-final-biofouling-report

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SOURCE Neptune Robotics

Technology

transcosmos organizes a well-digging volunteer project in Vietnam

Published

51 minutes ago

April 20, 2026

Aiming to address community-specific, long-term challenges through continuous efforts in environmental conservation, child support, and infrastructure support projects

TOKYO, April 20, 2026 /PRNewswire/ — transcosmos today announced that transcosmos technology Vietnam co., ltd. (Headquarters: Ho Chi Minh City, Vietnam; CEO: Daisuke Kamada; transcosmos Technologies Vietnam, TTV), its wholly owned subsidiary specializing in agile software development services in Vietnam, has organized a well-digging volunteer project in Kon Tu Ma Village, Mang Den, Kon Plong District, Quang Ngai Province, located in Vietnam’s Central Highlands.

In 2022, TTV initiated an employee-led TTV Volunteering Club to boost unity and foster social awareness among employees. Today, approximately 20 employees participate in volunteering activities, led by 10 club members, engaging in initiatives such as environmental conservation, child support, and infrastructure support projects.

This time, the project was carried out in Mang Den, a beautiful place known as “the second Da Lat.” Nestled amidst gently sloping mountains and abundant virgin forests, Mang Den is located on a tranquil plateau with a comfortable, cool climate throughout the year. Many ethnic minority groups sustain themselves mainly through agriculture; however, they face various challenges related to their living environment, medical care, and education. Children living in remote mountainous areas, in particular, face severe conditions.

In Mang Den, TTV has been carrying out volunteering activities for these children by providing meals and clothing, as well as recreational events and interaction programs. To further deepen these initiatives, TTV has dug a well to provide clean water to Kon Tu Ma Village and has also provided food and daily necessities.

With the Village Mayor, A Reo, and Mr. Hia, who is in charge of public safety, in attendance, TTV handed over the completed well at the grand opening ceremony. At the ceremony, Mayor A Reo commented, “This will not only help improve daily life, but also provide a secure environment even during dry seasons. We appreciate TTV’s support and thank you for your continued assistance.”

With the aim of establishing safe and sustainable water supply systems, TTV will continue to consider possibilities for supporting the development of water storage facilities and water purification systems. Guided by the belief that helping communities address community-specific, long-term challenges—going beyond temporary support—is the ideal approach, TTV is committed to continuing its volunteering activities.

*transcosmos is a trademark or registered trademark of transcosmos inc. in Japan and other countries.

*Other company names and product or service names used here are trademarks or registered trademarks of respective companies.

About transcosmos inc.

transcosmos launched its operations in 1966. Since then, we have united superior “people” with cutting-edge “technology” to enhance the competitive strength of our clients by providing them with superior and valuable services. transcosmos currently offers services that support clients’ business processes, focusing on both sales expansion and cost optimization through our 186 bases across 36 countries/regions with a focus on Asia, while continuously pursuing Operational Excellence. Furthermore, following the expansion of the e-commerce market on a global scale, transcosmos provides comprehensive One-Stop Global E-Commerce Services to deliver our clients’ excellent products and services to consumers in 46 countries/regions around the globe. transcosmos is committed to treating the challenges of its clients and society as its own—discussing and addressing their issues from planning to execution—and Make It Real, Together. Visit us here https://www.trans-cosmos.co.jp/english/

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SOURCE transcosmos inc.

Technology

Agoda Launches brand new ‘What a Save!’ campaign in India

Published

51 minutes ago

April 20, 2026

NEW DELHI, April 20, 2026 /PRNewswire/ — Digital travel platform Agoda is ready to save the day and travelers’ wallets with its fresh “What a Save!” campaign. This lighthearted set of digital ads, including three unique videos, blends humor with creativity to highlight real savings of up to 50% off on domestic hotel bookings.

In the campaign’s videos, viewers are treated to unexpected acts of heroism. One shows a beachgoer rescuing a dolphin washed ashore, with the crowd exclaiming “What a save!” only for the hero to cheekily add, “Actual savings happen on Agoda.” Another video features a girl performing the Heimlich maneuver on a choking peacock, with a grateful mom echoing the same sentiment about Agoda’s savings.

Gaurav Malik, Country Director India at Agoda, shared, “With the new ‘What a Save!’ campaign, we’re blending humor with genuine value. Agoda aims to make travel planning as enjoyable as the journey itself. Wherever travelers venture, booking with Agoda ensures they’ll be amazed and exclaim, ‘What a Save!’.”

In addition to the videos, Agoda is rolling out digital creatives and teaming up with popular creators like Aparshakti Khurana, Raghu and Rajiv of Roadies fame, and Gajraj Rao. This dynamic content lineup is set to engage audiences and highlight Agoda’s knack for great deals and a delightful booking experience.

Agoda’s “What a Save!” campaign is now live on Meta platforms, YouTube and other digital channels. It showcases the platform’s vast offerings, including over 6 million holiday properties, more than 130,000 flight routes, and over 300,000 activities, all of which can be combined in a single booking. Travelers can explore these offerings and find the best deals on Agoda’s mobile app. For more information, visit Agoda.com or download the Agoda mobile app.

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