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Implantica announces excellent RefluxStop™ investigator initiated study results published in Scientific Reports, a Nature journal

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VADUZ, Liechtenstein, July 30, 2024 /PRNewswire/ — Implantica AG (publ.), a medtech company at the forefront of introducing advanced technology into the body, announces the independent study ‘Multicentric short term and safety study of ineffective esophageal motility (IEM) patients treated with RefluxStop device’ was recently published in Nature Scientific Reports.

This investigator-initiated independent multicenter study was conducted at the General Hospital of the Medical University of Vienna, Austria, and King Edward VII Hospital in London, UK, from 2021 through 2023. All 40 patients had Ineffective Esophageal Motility (IEM) preoperatively, a notoriously difficult-to-treat subgroup of GERD patients.

Three months after the RefluxStop™ procedure, symptoms completely resolved or improved in 90% of the patients, PPI consumption was reduced by 84% and Quality of Life GERD-HRQL score was reduced from 32.8 to 6.6, an improvement of 80%, with limited side effects.

Patients with ineffective esophageal motility (IEM) have a weaker transportation of food down the esophagus and, therefore, often have swallowing difficulties. These patients are usually not recommended for surgery with standard of care surgical methods because they encircle and put pressure on the food passageway causing swallowing problems to worsen. This patient group comprises about one-third of the acid reflux sufferers that have no well working treatment today.

Prof. Dr. Sebastian Schoppmann of the Medical University of Vienna says, “It’s exciting to conduct the first real-world multicenter study assessing the safety and efficacy of the RefluxStop procedure. We found patients treated with RefluxStop experienced substantial improvements in quality of life and reflux symptoms with minimal safety issues despite all having ineffective esophageal motility. IEM is a well-known group of patients without any effective treatment options.” He adds, “Given RefluxStop’s great promising early results showing significant improvement in patient outcomes in GERD, we are now planning additional studies to validate our findings further and hopefully establish this as an effective treatment option to help the widely underserved GERD patient population.”

Dr. Peter Forsell, inventor of RefluxStop™ and CEO & Founder of Implantica adds, “It is exciting to see how well RefluxStop treats IEM patients with limited side effects since it does not encircle the food passageway like existing standard of care surgical treatments. Since launch several hundred patients with IEM have been operated with RefluxStop and the results have been excellent. We are very pleased to see these results published in Scientific Reports, a journal of Nature portfolio, which is a hallmark of high-quality research work, and would like to thank Prof Schoppmann and Dr. Boyle for their dedicated work. It is satisfying to see the RefluxStop procedure used for GERD patients with esophageal motility disorders given that historically these patients were largely excluded from the existing anti-reflux surgical treatments. RefluxStop™ has established itself as a great hope for these difficult-to-treat patients as well as millions of other GERD patients who would benefit from the RefluxStop procedure with its unique mechanism of action.”

For further information, please contact:
Nicole Pehrsson, Chief Corporate Affairs Officer
Telephone (CH): +41 (0)79 335 09 49
nicole.pehrsson@implantica.com

Implantica is listed on Nasdaq First North Premier Growth Market in Stockholm.

The company’s Certified Adviser is FNCA Sweden AB, info@fnca.se

The information was sent for publication, through the agency of the contact person set out above, on July 30, 2024, at 08:00 a.m. (CET).

About Implantica

Implantica is a medtech group dedicated to bringing advanced technology into the body. Implantica’s lead product, RefluxStop™, is a CE-marked implant for the prevention of gastroesophageal reflux that will potentially create a paradigm shift in anti-reflux treatment as supported by successful clinical trial results. Implantica also focuses on eHealth inside the body and has developed a broad, patent protected, product pipeline based partly on two platform technologies: an eHealth platform designed to monitor a broad range of health parameters, control treatment from inside the body and communicate to the caregiver on distance and a wireless energizing platform designed to power remote-controlled implants wirelessly through intact skin. Implantica is listed on Nasdaq First North Premier Growth Market (ticker: IMP A SDB). Visit www.implantica.com for further information.

About RefluxStop™

RefluxStop™ is a new innovative treatment that has the potential to spur a paradigm shift in anti-reflux surgery. It’s unique mechanism of action differentiates it from standard of care and current surgical solutions. Longer established surgical options for GORD involve encircling the food passageway to support the lower oesophageal sphincter’s closing mechanism and are commonly associated with side effects such as swallowing difficulties, pain when swallowing and inability to belch and/or vomit.

In contrast, the RefluxStop™ device treats the cause of acid reflux without encircling and putting pressure on the food passageway. It restores and maintains the lower oesophageal sphincter in its original, natural position.

The RefluxStop™ mechanism of action is focused on reconstructing all three components of the anti-reflux barrier, that if compromised could possibly result in acid reflux. It restores and supports the natural anatomical physiology of the body allowing the body to itself solve the problem with acid reflux.

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Media Contact:
Implantica AG
Juanita Eberhart, VP Marketing & Advocacy
M: +1 925-381-4581
juanita.eberhart@implantica.com

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Genedata Expands AI Discovery Workflows with NVIDIA BioNeMo Open Models, Including the New RFD4-Proteina Release

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Bringing next-generation binder design models into production discovery

BASEL, Switzerland, Oct. 22, 2026 /PRNewswire/ — Genedata, a Danaher company, and the leading provider of enterprise software solutions for biopharmaceutical R&D, today announced the addition of the new RFD4-Proteina binder design model into Genedata’s AI-enabled discovery workflows, following the model’s introduction at NVIDIA GTC Berlin. As an early ecosystem partner, Genedata is among the first companies to make RFD4-Proteina available within its production discovery workflows. By connecting AI-generated molecular designs, scientific data, and laboratory results, Genedata helps researchers transform AI predictions into continuous learning cycles that accelerate biologics discovery.

The workflow begins with scientists defining target characteristics and required properties using Genedata’s AI co-scientist. NVIDIA’s open protein design models then generate and evaluate candidate binders within Genedata. As candidates move into laboratory testing, results are captured and linked back to the original designs, helping scientists refine and rank the next round.

“Advances in AI are creating unprecedented opportunities for protein and antibody discovery, but unlocking their full value requires more than access to powerful models alone,” said Othmar Pfannes, Ph.D., President of Genedata. “Researchers need a way to connect molecular design, experimental execution, and scientific data into a continuous learning process. Genedata serves as the digital backbone that brings these elements together, helping scientists evaluate more candidates before testing, preserve the scientific context behind each outcome, and build knowledge from one discovery cycle to the next.”

While advances in generative AI are rapidly expanding what scientists can design, many organizations still struggle to operationalize these models within production scientific research workflows. Genedata provides the orchestration, governance, and scientific data foundation needed to deploy NVIDIA BioNeMo open models, including RFD4-Proteina, directly within the discovery workflows scientists use every day. Researchers can apply AI-generated designs within established processes while maintaining lineage, traceability, and scientific context across the discovery lifecycle.

Within Danaher’s autonomous laboratory initiative, these capabilities connect AI, automation, and scientific data in a closed-loop discovery framework where each experimental outcome informs the next design cycle, creating a continuous learn-and-improve process that advances science while keeping scientists in control.

About Genedata
Genedata, a Danaher company and the leading provider of enterprise software solutions for biopharma R&D, transforms biopharma data into intelligence. Our innovative solutions combine deep science, technology, and AI domain knowledge. Leading biopharma organizations and cutting-edge biotechs partner with Genedata to digitalize and automate complex data workflows. Our advanced analytics and embedded AI enable data-driven decisions. From early discovery through development to the clinic, Genedata solutions drive innovation and maximize ROI being trusted by customers worldwide for more than 25 years.

www.genedata.com
LinkedIn | YouTube

About Danaher
Danaher is a leading global life sciences and diagnostics innovator, committed to accelerating the power of science and technology to improve human health. Through our connected ecosystem of industry-leading businesses, we work side by side with customers to solve their most complex scientific and clinical challenges—helping move innovations from discovery to delivery faster for patients who depend on them. Powered by the Danaher Business System, our advanced science and technology and proven ability to innovate help enable faster, more accurate diagnoses and reduce the time, cost, and risk required to discover, develop, and deliver life-changing therapies. Through continuous improvement and operational excellence, our approximately 60,000 associates worldwide are focused on delivering lasting impact and improving quality of life around the world, while building a healthier, more sustainable tomorrow. Explore more at www.danaher.com.

Disclaimer

The statements in this press release that relate to future plans, events or performance are forward-looking statements that involve risks and uncertainties, including risks associated with uncertainties related to contract cancellations, developing risks, competitive factors, uncertainties pertaining to customer orders, demand for products and services, development of markets for the Company’s products and services. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. The Company undertakes no obligation to release publicly the result of any revisions to these forward-looking statements that may be made to reflect events or circumstances after the date hereof or to reflect the occurrence of unanticipated events.

All product and service names mentioned are the trademarks of their respective companies.

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SOURCE Genedata

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Bybit AI Empowers Users with Their Personal Financial Edge, Adding Personalization and Memory

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DUBAI, UAE, Oct. 22, 2026 /PRNewswire/ — Bybit, the New Financial Platform trusted by more than 80 million users worldwide, has announced new personalization and memory features for Bybit AI, its in-app intelligent conversational layer. Bybit AI now builds a profile from each user’s assets, positions, behavior and risk profile, connecting wealth, markets and trading across the Bybit ecosystem.

Launched in September, Bybit AI organically unifies Bybit’s core services within a single chat interface. The newly added features extend its capacity from responding to individual requests to maintaining a continuous understanding of the user, giving each user their personal financial edge.

Putting the user at the center, Bybit AI is evolving on three pillars:

Personalized: With permissions granted and limits set, Bybit AI analyzes actual account information, including financial behavior and risk profile alongside assets and positions, to generate outputs tailored to the individual.Connected: Bybit AI links Markets, Trading, Earn, Card and other Bybit products, drawing on the full picture of a user’s holdings and activity rather than a single product.Remembered: Users can proactively share their preferences with Bybit AI, which retains this context through long-term memory so that each conversation builds on the previous one.

The release also introduces Featured, a set of customized entry points for specific use cases. Each entry point offers predefined prompts, such as generating a wealth management plan based on a user’s assets and risk tolerance, and returns structured analysis with key data, clear insights and suggested next steps.

Bybit AI supports main account operations while giving users the option to deploy it within a dedicated Bybit AI sub-account. The AI-powered assistant is built on a security-first architecture. Outputs are provided for informational purposes only and do not constitute investment advice. Instructions are executed in chats only after customer authorizations.

Bybit expects to introduce further updates to Bybit AI as it continues to build toward AI-native financial services, with conversational intelligence positioned as core infrastructure.

To explore Bybit AI and learn more about how it works, users may visit: Bybit AI  – Learn how to use Bybit through conversation.

#Bybit  / #NewFinancialPlatform 

About Bybit

Bybit is The New Financial Platform.

We believe every person should have access to every financial opportunity on earth. That’s why we’re building the first intelligent platform that connects anyone, anywhere to the world’s finance.

Trusted by more than 80 million users worldwide, Bybit brings together investing, trading, payments, and wealth-building in a single secure and intelligent ecosystem. Through the combination of AI-powered technology, deep global liquidity, robust security, and transparent operations, Bybit makes global finance more accessible, efficient, and empowering for everyone.

Built for everyone. Powered by intelligence. Open to the world.

Learn more at Bybit.com.

For more details about Bybit, please visit Bybit Press

For media inquiries, please contact: media@bybit.com

For updates, please follow: Bybit’s Communities and Social Media

Facebook | Instagram | LinkedIn | Reddit | Telegram | TikTok | X | Youtube

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Poq is now a Shopify Certified Technology Partner

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LONDON, Oct. 22, 2026 /PRNewswire/ —  poq, the native mobile app platform for retail brands, today announced it has been recognised as a Shopify Certified Technology Partner. Shopify’s certification is reserved for app partners that meet Shopify’s standards for quality, security, performance and support. poq is now listed in the Shopify Technology Partner Directory and the Certified Technology Partner App Store Collection, making it easier for enterprise Shopify merchants to find and adopt a proven native app platform.

poq already powers native iOS and Android apps for joint customers including Ardene, Steve Madden UK, e.l.f. Beauty (globally), Horze (pan-European), Mamas & Papas (UK) and ECO. Modern Essentials (ANZ and UK). Across the poq platform, shoppers convert at 1.8 times the rate of mobile web, based on the median across 21 brands from January 2025 to January 2026.

“Certification from Shopify is independent validation that poq meets the high standard Shopify sets for its technology partners,” said Jay Johnston, CEO of poq. “Our customers use their apps to build loyalty and drive repeat purchases from their most valuable shoppers. This recognition means more Shopify merchants can launch a high-performing native app with confidence, on a platform already proven at scale across four continents.”

Results for Shopify Brands

European equestrian retailer Horze moved to Shopify and chose to stay with poq for its native app. “After choosing to continue working together, I can confidently say that this was absolutely the right decision. The level of motivation, ownership, and commitment the poq team demonstrated throughout the project was truly impressive,” said Dominik Schlag, CFO of Horze.

In the UK, Mamas & Papas uses its poq app to make shopping easier for busy parents. “Our poq app makes shopping with us quick and easy wherever they are, and drives loyalty and repeat purchases,” said Jo Molineux, Digital Director at Mamas & Papas.

About poq

poq is a leading Software-as-a-Service (SaaS) platform that empowers retailers and brands to create and maintain engaging, high-performance native mobile apps. With a focus on driving customer engagement and revenue, poq’s platform enables seamless integration, powerful personalisation, and an enhanced shopping experience for businesses worldwide. Learn more at poqcommerce.com.

Media contact
Emma Williams, Marketing Lead
emma.williams@poqcommerce.com  

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SOURCE Poq

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