Technology

Atomic Antibiotics Developed by Czech Scientists Counter Bacterial Resistance

Published

2 years ago

October 3, 2024

OSTRAVA, Czech Republic, Oct. 3, 2024 /PRNewswire/ — Scientists from Palacký University Olomouc (UP) and the Technical University of Ostrava (VSB-TUO), in collaboration with colleagues from China, have discovered a groundbreaking method for developing a new generation of antibiotics. These antibiotics not only combat a wide range of bacteria but also effectively prevent the development of bacterial resistance. By employing atomic engineering, the researchers transformed manganese—a trace element vital for human health—into a potent antibiotic by embedding it in the structure of chemically modified graphene. Tests conducted on animal models have demonstrated the material’s significant potential, particularly in localized therapies such as wound healing. The discovery has been published in the prestigious journal Advanced Materials, and the team has filed a European patent to safeguard their innovation.

“The material we developed successfully kills and inhibits the growth of all bacteria we studied, including highly resistant pathogens. It operates at low concentrations, which are completely harmless to human cells. Furthermore, bacteria cannot develop resistance to it, thus addressing one of modern medicine’s most pressing challenges. These promising results position atomic antibiotics for practical use in the near future,” said Radek Zbořil, a physical chemist and author of the research concept, who works at the Czech Advanced Technology and Research Institute (CATRIN UP) and the Centre for Energy and Environmental Technologies (CEET) at VSB-TUO.

A Frontal Attack with Manganese

In developing this antibiotic, the scientists drew on their expertise in graphene chemistry and atomic engineering, fields they have extensively studied in recent years. This time, they utilized a graphene derivative enriched with oxygen and nitrogen atoms, chemically incorporating manganese—a transition metal that is involved in metabolism, bone formation, blood sugar regulation and cellular protection against oxidative stress.

“We chose to target one of the strongest defences of bacteria—the carbohydrates in their cell walls and membranes, which are crucial for their survival. These carbohydrates play a protective role, facilitate substance transfer, enable communication with the environment, and serve as energy reserves. By chemically binding manganese to specific carbohydrate groups, we suppressed these critical functions, ultimately causing cell death. The graphene carrier plays an essential role by ensuring the delivery of manganese ions to the bacterial surface, which enables a direct chemical attack on the carbohydrate molecules,” Zbořil explained.

Effective Against Even the Most Resistant Bacteria

The new material also shows remarkable efficacy against bacteria that existing antibiotics struggle to combat. “We observed an excellent bactericidal effect against all bacteria from the ESCAPE group, which includes highly resistant bacterial pathogens. These bacteria are particularly dangerous because they are resistant to conventional antibiotics, which complicates treatment and increases the risk of severe infections, especially in hospital settings. The atomic antibiotic was the only agent that proved effective against all resistant bacteria, compared to commercial antibiotics,” said David Panáček, the first author of the paper, from CATRIN UP and CEET VSB-TUO.

The researchers tested the atomic antibiotic’s effect not only in laboratory settings but also in mouse models in collaboration with their Chinese colleagues. “In in-vivo tests, skin infections caused by resistant strains of Staphylococcus aureus (golden staph) healed quickly and effectively, with all markers of inflammation significantly reduced. We are now considering its use for wound dressings or antibacterial treatments on surfaces of artificial materials. There is tremendous potential to prevent bacterial biofilms from forming on devices such as artificial joint replacements, stents, or cannulas. Given its mode of action, this new material could also help prevent secondary infections, which would have a major impact on healthcare,” said Milan Kolář, a microbiologist and Dean of the Faculty of Medicine and Dentistry at Palacký University Olomouc, who played a key role in the research.

Atomic Antibiotics Open New Possibilities

The research team plans to continue exploring the material’s potential for systemic antibiotic treatments. “Some serious infections are now untreatable with existing antibiotics, and bacterial sepsis is becoming an increasingly common cause of death. We aim to test atomic antibiotics’ effectiveness in treating the most severe bacterial diseases,” Kolář added.

According to the United Nations, if bacterial resistance continues to rise at its current pace, by 2050 untreatable infections caused by multidrug-resistant bacteria could become the leading cause of death worldwide. These so-called ‘superbugs’ pose a global threat, necessitating the development of new antibacterial agents that can bypass the defence mechanisms bacteria use to protect themselves. This research, which also involved colleagues from the Faculty of Science at Palacký University Olomouc and two Chinese institutions, highlights the untapped potential of atomic engineering in addressing one of humanity’s most urgent scientific and social challenges.

Read the paper at: Single Atom Engineered Antibiotics Overcome Bacterial Resistance – Panáček – Advanced Materials – Wiley Online Library

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Technology

The Inner Circle acknowledges Colleen Reilly as a Pinnacle Professional Member Inner Circle of Excellence

Published

5 hours ago

April 24, 2026

PORT ST. JOE, Fla., April 24, 2026 /PRNewswire/ — Prominently featured in The Inner Circle, Colleen Reilly is honored as a Pinnacle Professional Member Inner Circle of Excellence for her contributions to Transforming Catering and Event Services in Northwest Florida.

Since 2015, Colleen Reilly has served as founder and CEO of Catering Connections, a company that has redefined catering in Northwest Florida’s beach communities through innovation, collaboration, and community focus. Guided by her motto “Just one call feeds them all,” Ms. Reilly established a unique model by partnering with local restaurants to showcase their specialties, fostering unity among businesses while providing clients with one-of-a-kind event experiences.

With over 15 years of industry expertise, Ms. Reilly specializes in coordinating weddings, family reunions, and corporate events, managing every detail from client consultation to menu planning and flawless execution. Her dedication to service has earned Catering Connections multiple recognitions, including the Couples Choice Award from WeddingWire from 2021 to 2025, the Best of Florida Award from 2022 to 2024, and the Lux Life Hospitality and Catering Award in 2023 and 2024.

Ms. Reilly’s career foundation includes an associate degree in paralegal studies, magna cum laude, from Volunteer State College, a reflection of her meticulous approach to detail and commitment to excellence. Beyond her business, she serves her community as a board member of the Historic St. Andrews Waterfront Partnership and as president of Friends of the Governor Stone Inc., a nonprofit dedicated to preserving maritime heritage in Panama City. Her previous civic contributions include serving five years as a guardian ad litem, advocating for children within the legal system, and volunteering as a school chaperone for international student trips.

A leader who blends innovation with service, Ms. Reilly continues to grow Catering Connections while deepening her commitment to the local community. Looking ahead, she remains dedicated to expanding her company’s impact, bringing people together, and creating meaningful experiences through food and fellowship.

Contact: Katherine Green, 516-825-5634, editorialteam@continentalwhoswho.com

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SOURCE The Inner Circle

Technology

Media Contributor Kianga Moore to Host Executive Media Roundtable On AI’s Transformational Impact in Retail

Published

5 hours ago

April 24, 2026

Leaders from AdFury.ai, Vendormint, and New Nexus Group to Explore Real-Time Decision-Making, Resilience, and Growth in a Volatile Market

NEW YORK, April 24, 2026 /PRNewswire/ — As retailers navigate ongoing economic uncertainty, supply chain volatility, and rapidly shifting consumer expectations, the upcoming convening of a high-level roundtable discussion will examine how artificial intelligence is reshaping the retail landscape in real time.

Moderated by Media Contributor Kianga Moore, to be held on Wednesday, April 29 at 11h00am (EST), the roundtable will bring together senior leaders from AdFury.ai, Vendormint and New Nexus Group to discuss how modern enterprise platforms are leveraging AI to drive agility, efficiency, and long-term resilience across the retail ecosystem.

The discussion will additionally focus on how AI is enabling retailers to respond dynamically to changing demand signals, optimize marketing investments, and strengthen interoperability across increasingly complex vendor and marketplace networks.

“Retailers today are operating in a constant state of disruption”, stated Kianga Moore. “This roundtable will explore how AI is not just a tool for efficiency, but a strategic asset for anticipating change and building more resilient, adaptive American enterprise.”

Key discussion topics will include remarks on how, for example, enterprise AI platforms are helping retailers respond instantly to fluctuations in consumer demand, pricing pressures, and external supply chain disruptions and the role of AI in enhancing interoperability across vendors, partners, and marketplaces to create more agile and resilient retail infrastructures in 2026.

Rob Gonda, Chief Technical Officer at Vendormint, stated that, “Interoperability is the backbone of modern retail. AI enables seamless communication between platforms, vendors, and marketplaces—turning fragmented systems into cohesive, responsive ecosystems that can adapt under pressure.”

Discussion topics will also include machine learning’s ability to optimize ad spend, improving personalization, and delivering measurable ROI while maintaining brand trust and regulatory compliance.

Eric Howerton, Co-Founder and Chief Growth Officer of AdFury.ai, added that,”AI is fundamentally changing how brands approach customer acquisition. By leveraging machine learning through fine-tuned, retail-specific agentic flows, we can not only optimize ad spend in real time, but we can also ensure messaging is personalized, compliant, and aligned with evolving consumer expectations.”

And indeed the roundtable will include discussions on how AI-powered predictive analytics can help businesses anticipate economic, technological, and geopolitical disruptions ahead—and plan accordingly.

Cheryl Yarbrough, Vice President of Partnerships at New Nexus Group added that, “Resilience in retail is no longer built in quarterly planning cycles-it’s built in real time. AI gives organizations the ability to identify disruptions before they cascade, pivot strategies before momentum is lost, and maintain continuity when the market moves faster than any human team can react alone.”

The roundtable will be held via Zoom TeleConference, with questions from the press and key stakeholders to follow opening remarks and a 30-minute Q&A between the moderator and the panelists.

For all media inquiries and to register to attend, please contact: Sam Amsterdam, Amsterdam Group Public Relations Inc. – Sam@AmsterdamGroup.net / +1 (202) 910-8349

Vendormint (https://vendormint.com)New Nexus Group (https://www.newnexusgroup.com)AdFury.ai (https://www.adfury.ai)

Samuel Amsterdam
Communications Counsel
Vendormint
samuelamsterdam@gmail.com

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SOURCE Vendormint

Technology

Fairway Home Mortgage Earns Prestigious USA TODAY Top Workplaces Award For 6th Consecutive Year

Published

6 hours ago

April 24, 2026

Fairway CEO Steve Jacobson Named #1 Leadership Award Winner of Companies With 2500+ Employees

MADISON, Wis., April 24, 2026 /PRNewswire/ — Fairway Home Mortgage announced that it has earned the prestigious 2026 USA TODAY Top Workplaces award. This is the sixth year in a row Fairway achieved this honor.

The award honors organizations with 150 or more employees that have created exceptional, people-first cultures. This year, more than 40,500 organizations were invited to participate. The winners are recognized for their commitment to fostering a workplace environment that values employee listening and engagement. USA TODAY showcased the winners at the National Awards Summit in Nashville. Watch the video of the event here.

“Being recognized with this award reflects Fairway’s commitment to bringing our people together face-to-face,” said Fairway’s CEO and Founder Steve Jacobson. “Companies are better when their people are around each other. People need each other and they learn from each other, and we’re very intentional about creating opportunities for in-person collaboration at Fairway.”

Jacobson demonstrated that in-person collaboration when he traveled to Knoxville this week with Fairway Senior Vice President Dan Richards to spend time with one of Fairway’s branches and their local real estate partners. “We engaged in real conversations about the market, discussed what people are seeing on the ground, and talked about how Fairway keeps showing up for clients,” said Richards. “It’s a reflection of the same hands-on approach that has defined Fairway’s culture for more than two decades.”

“To be named a Top Workplace for six consecutive years speaks to Fairway’s leadership, our mindset, and the empowerment of our staff,” said Fairway’s Chief People and Engagement Officer Julie Fry. “Our strength isn’t just what we offer employees. What sets a top workplace apart is the daily commitment to people—prioritizing connection, valuing contributions, and creating an environment where employees feel energized to serve because they feel valued first.”

The winners are determined by authentic employee feedback captured through a confidential survey conducted by Energage, the HR research and technology company behind the Top Workplaces program since 2006. The results are calculated based on employee responses to statements about Workplace Experience Themes, which are proven indicators of high performance.

“Earning a USA TODAY Top Workplaces award is a testament to an organization’s credibility and commitment to a people-first culture,” said Eric Rubino, CEO of Energage. “This award, driven by real employee feedback, is more than just a recognition — it’s proof that your employees believe in the organization and its leadership. Job seekers and customers look for this trusted badge of credibility and excellence. It signals a company that values its people, and that kind of culture resonates in today’s competitive market”

About Fairway Home Mortgage
Madison, WI- and Carrollton, TX-based Fairway Independent Mortgage Corporation (NMLS #2289) is a full-service mortgage lender licensed in all 50 states. Fairway is the #2 overall retail lender in the U.S.

About Energage
Making the world a better place to work together.™
Energage is a purpose-driven company that helps organizations turn employee feedback into useful business intelligence and credible employer recognition through Top Workplaces. Built on 20 years of culture research and the results from 30 million employees surveyed across more than 80,000 organizations, Energage delivers the most accurate competitive benchmark available. With access to a unique combination of patented analytic tools and expert guidance, Energage customers lead the competition with an engaged workforce and an opportunity to gain recognition for their people-first approach to culture. For more information or to nominate your organization, visit energage.com or topworkplaces.com.

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SOURCE Fairway Home Mortgage