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Illumina advances NovaSeq X Series, delivering single-flow-cell system, software upgrade, and new kits to enable multiomic applications

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Software upgrade advances complete workflow solutions

New NovaSeq X 25B 100-cycle and 200-cycle kits enhance multiomic capabilities on NovaSeq X, and enable newly released Illumina Single-Cell Prep

SAN DIEGO, Jan. 7, 2025 /PRNewswire/ — Illumina, Inc. (NASDAQ: ILMN), a global leader in DNA sequencing and array-based technologies, today announced a series of updates to its NovaSeq X Series, delivering the NovaSeq X single-flow-cell system alongside a cutting-edge software upgrade and new kits.

Now in the market for the first time, the single-flow-cell NovaSeq X Sequencing System offers the same high-quality flow cells and speed as the NovaSeq X Plus Sequencing System—Illumina’s most rapidly adopted and utilized high-throughput sequencing platform to date—at a more accessible cost for labs with lower volume. The sequencers began shipping in December, and simultaneously the company introduced the software v1.3 upgrade for the NovaSeq X Series to elevate sequencing performance and advance data quality. Additionally, new NovaSeq X 25B 100- and 200-cycle kits began shipping in December, which will be key enablers of multiomic applications, including the Illumina Single-Cell 3′ RNA Prep (Illumina Single Cell Prep), now available under Illumina’s brand following the company’s acquisition of Fluent.

“This is the same instrument the scientific community has come to rely on for next-generation sequencing, now with upgraded software, new kits, and the option for a lower volume,” said Steve Barnard, PhD, chief technology officer of Illumina. “Based on customer input, we’ve invested heavily in innovations to make the platform even stronger and more versatile, supporting total workflows with flexible applications spanning genomics and multiomics. Customers are already raving about the powerful capabilities of the software upgrade.”

Customers affirm the value of the software upgrade 

The newly launched software upgrade delivers key enhancements that optimize sequencing workflows. Version 1.3 provides laboratories with improved sequencing accuracy and higher yields to ensure dependable and precise results, even with challenging, low-diversity samples. The reduction in PhiX dependency also means more usable data per run, helping researchers maximize their throughput and their confidence in their sequencing outputs. 

Génome Québec is a nonprofit organization that provides genomic services for researchers in the academic and industrial fields of 45 countries. In their experience testing the v1.3 software they noted a significant leap in data quality across a broad variety of library types. Geneviève DonPierre, team leader of NGS Sequencing at Génome Québec, stated, “The increased yield, enhanced sequencing accuracy, reduced PhiX dependency, and optimized handling of low-diversity libraries have transformed our operations. This update ensures consistently reliable outputs and empowers us to achieve superior results, reinforcing our confidence in every sequencing run.” 

Broad Clinical Labs also participated in early-access testing. The organization’s director of Laboratory Operations, Tom Howd, said: “We have observed significant high-quality data yield increases in early testing of the version 1.3 update on our NovaSeq X Plus fleet. We are eager to make these yield increases available to all our users to continue to advance their science.”

Bert Groet, laboratory specialist clinical genetics and team leader of the NGS core facility at University Medical Center Utrecht, affirms: “With the release of software version 1.3 on the NovaSeq X Plus, Illumina brings to our genome lab a decisive development to transition from whole-exome-based to whole-genome-based analysis. The significant increase in total sequencing yield, without compromise to high Q30 scores, ensures the promise of high throughput and high-quality whole-genome sequencing we can rely on to deliver answers to those we will be serving.”

Expanding capabilities with the 25B 100-cycle and 200-cycle kits

The new 25B 100-cycle and 200-cycle kits for the NovaSeq X Series, which began shipping in December, are optimized for counting applications and other assays at scale, offering shorter turnaround times and more cost-effective runs. By providing flexibility in run sizes and cycle counts, the 25B kits address the evolving needs of clinical specialty labs, academic core labs, and service providers.

Illumina Single-Cell Prep

Also announced today, Illumina Single-Cell Prep, formerly Fluent PipSeq V, is now available and shipping to customers with broad compatibility across Illumina’s NGS platform portfolio, including NextSeq 1000/2000, NovaSeq 6000, and NovaSeq X. The single-cell sample prep technology removes many of the barriers and limitations of current methods, enabling scalability of experiments from hundreds to millions of cells with the same process and turnaround time. Low equipment cost, lower cost per cell, and high sensitivity allow for customers who are new to single-cell sequencing to adopt the technology quickly and easily, with exceptional performance while providing cost-efficient scaling to large numbers of cells for analysis that is possible only on the NovaSeq X 25B flow cell.

At the annual meeting of the American Society of Human Genetics in November, Shane Liddelow, PhD, associate professor in the Department of Neuroscience and Physiology at NYU Grossman School of Medicine, presented early access data and insights on the innovative technology enabling the sequencing of challenging cell types, such as astrocytes and brain tissue, which are notoriously difficult to analyze with microfluidic devices due to issues like clogging and other technical barriers.

The new 25B kits for the NovaSeq X Series are compatible with Illumina Single-Cell Prep, introducing highly efficient, affordable, and accurate workflows for large scale, single-cell analysis projects. Illumina Single-Cell Prep provides streamlined bioinformatics workflows from NovaSeq X Series sequencers streaming data directly into automated DRAGEN analysis in Illumina’s informatics cloud solutions. Partek Flow enables comprehensive visualization and interpretation of large-scale Illumina Single-Cell Prep data sets for differential expression and biomarker discovery.

Use of forward-looking statements

This release may contain forward-looking statements that involve risks and uncertainties. Among the important factors to which our business is subject that could cause actual results to differ materially from those in any forward-looking statements are: (i) challenges inherent in developing and launching new products and services, including modifying and scaling manufacturing operations, and reliance on third-party suppliers for critical components; (ii) our ability to manufacture robust instrumentation and consumables; and (iii) the acceptance by customers of our newly launched products, which may or may not meet our and their expectations, together with other factors detailed in our filings with the Securities and Exchange Commission, including our most recent filings on Forms 10-K and 10-Q, or in information disclosed in public conference calls, the date and time of which are released beforehand. We undertake no obligation, and do not intend, to update these forward-looking statements, to review or confirm analysts’ expectations, or to provide interim reports or updates on the progress of the current quarter.

About Illumina

Illumina is improving human health by unlocking the power of the genome. Our focus on innovation has established us as a global leader in DNA sequencing and array-based technologies, serving customers in the research, clinical, and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture, and other emerging segments. To learn more, visit illumina.com and connect with us on X, Facebook, LinkedIn, Instagram, TikTok, and YouTube.

Contacts

Investors:
Salli Schwartz
858-291-6421
IR@illumina.com

Media:
Christine Douglass
PR@illumina.com

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SOURCE Illumina, Inc.

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In HelloNation, Real Estate Expert Grace Frank Shares What to Know Before Relocating to Chattanooga

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CHATTANOOGA, Tenn., April 27, 2026 /PRNewswire/ — What should people consider before relocating to Chattanooga,TN? According to a HelloNation article, the move involves more than a change of address. Grace Frank of Grace Frank Group explains that housing options, schools, job opportunities, and lifestyle factors all play an important role in helping newcomers settle successfully in the city.

Housing is often the first decision to make. Chattanooga offers a wide range of real estate choices, from historic downtown homes to newer suburban subdivisions and rural properties with more space. Each option comes with trade-offs. Urban neighborhoods provide convenience and entertainment, suburban areas appeal to families with larger homes and school access, and rural living offers peace and quiet but may require longer commutes and fewer services.

Affordability is another factor that draws many people to the area. Compared to larger cities, Chattanooga’s housing prices and property taxes remain relatively moderate. Still, trends vary by neighborhood. Some areas near downtown are experiencing rapid growth and rising prices. Buyers and renters who study these patterns in advance are better able to match their budget with the right community.

For families, schools are central to the relocation decision. Hamilton County features public, private, and charter schools, each offering different strengths. Many families select neighborhoods based on school zones, while others consider private education or alternative programs. Reviewing school ratings, extracurricular options, and long-term academic opportunities helps ensure the best fit for children.

Employment opportunities also make Chattanooga an attractive place to move. The job market has been growing steadily, with strengths in logistics, healthcare, technology, and advanced manufacturing. Expansion from existing companies and new businesses entering the region have created stability in both housing and employment. Prospective residents, however, should review industry-specific opportunities to confirm their career goals align with local options.

Beyond housing, schools, and work, lifestyle factors help determine how well a move turns out. Chattanooga’s reputation as an outdoor destination is one of its strongest assets. Residents enjoy access to hiking trails, mountain biking, and water activities along the Tennessee River. The city also features cultural events, a thriving restaurant scene, and live music, making it appealing for those who want balance between work and recreation.

Planning the details of the move itself is just as important. A relocation checklist can simplify the process, including securing housing, transferring utilities, and registering vehicles. Those moving from out of state should also remember to update driver’s licenses, insurance, and voter registration. Attention to these details reduces stress and prevents unnecessary delays.

Local expertise can help make the transition smoother. A real estate professional who understands Chattanooga can guide newcomers through the city’s neighborhoods, school districts, and commuting options. Their insight can save time, prevent costly mistakes, and ensure that newcomers choose a location that fits both their practical needs and lifestyle goals.

Relocating to Chattanooga offers opportunities that combine affordability, career growth, and outdoor living. Families, retirees, and young professionals are all drawn to the area’s variety of neighborhoods, active lifestyle, and strong sense of community. With careful planning, the move can be both seamless and rewarding.

What to Know Before Relocating to Chattanooga highlights the most important factors for a successful transition. This is according to Grace Frank, Real Estate Expert of Chattanooga, TN, who provides practical advice for those considering a move in HelloNation.

About HelloNation
HelloNation is a premier media platform that connects readers with trusted professionals and businesses across various industries. Through its innovative “edvertising” approach that blends educational content and storytelling, HelloNation delivers expert-driven articles that inform, inspire, and empower. Covering topics from home improvement and health to business strategy and lifestyle, HelloNation highlights leaders making a meaningful impact in their communities.

View original content to download multimedia:https://www.prnewswire.com/news-releases/in-hellonation-real-estate-expert-grace-frank-shares-what-to-know-before-relocating-to-chattanooga-302754736.html

SOURCE HelloNation

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Hyperscale Data Subsidiary Ault Global Commodities Announces First Silver Purchase

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LAS VEGAS, April 27, 2026 /PRNewswire/ — Hyperscale Data, Inc. (NYSE American: GPUS), an artificial intelligence (“AI”) data center company anchored by Bitcoin (“Hyperscale Data” or the “Company”), today announced that its wholly-owned subsidiary Ault Global Commodities, Inc. (“AGC”) has completed its first purchase of physical silver, acquiring 10,000 ounces of .999 fine silver bullion. The transaction was executed through AGC’s strategic partner, Scottsdale Mint, LLLP, a leading private mint specializing in high-quality investment grade precious metals with which AGC has entered into a purchase and sale agreement (the “Agreement”).

This initial acquisition of silver under the Agreement marks the official launch of the Company’s precious metals strategy and represents a key step in the Company’s broader initiative to build a diversified commodities portfolio alongside its existing digital asset and AI operations, as well as its contemplated robotics plans, each as disclosed in prior press releases.

“This initial silver purchase represents more than merely an entry into precious metals; it reflects the continued evolution of the Company’s balance sheet,” stated Milton “Todd” Ault III, Executive Chairman of Hyperscale Data. “With more than $350 million in assets, including cash and Bitcoin, we are deliberately building a diversified balance sheet designed to endure across market cycles. We believe Bitcoin and precious metals will serve as foundational pillars of that strategy, combining the asymmetric upside of digital assets with the proven stability of hard commodities. As we continue to deploy capital, our objective is clear: Strengthen our asset base, expand our global portfolio of companies, and position Hyperscale Data to create long-term value through disciplined, opportunistic capital allocation.”

The Company expects AGC to make additional purchases in the future as it continues to scale its operations in the broader commodities sector.

For more information on Hyperscale Data and its subsidiaries, Hyperscale Data recommends that stockholders, investors and any other interested parties read Hyperscale Data’s public filings and press releases available under the Investor Relations section at hyperscaledata.com or available at www.sec.gov.

About Hyperscale Data, Inc.

Through its wholly owned subsidiary Sentinum, Inc., Hyperscale Data owns and operates a data center at which it mines digital assets and offers colocation and hosting services for the emerging AI ecosystems and other industries. Hyperscale Data’s other wholly owned subsidiary, Ault Capital Group, Inc. (“ACG”), is a diversified holding company pursuing growth by acquiring undervalued businesses and disruptive technologies with a global impact.

Hyperscale Data currently expects the divestiture of ACG (the “Divestiture”) to occur in the second quarter of 2027. Upon the occurrence of the Divestiture, the Company would be an owner and operator of data centers to support high-performance computing services, as well as a holder of the digital assets. Until the Divestiture occurs, the Company will continue to provide, through ACG and its wholly and majority-owned subsidiaries and strategic investments, mission-critical products that support a diverse range of industries, including an AI software platform, equipment rental services, defense/aerospace, industrial, automotive, medical/biopharma and hotel operations. In addition, ACG is actively engaged in private credit and structured finance through a licensed lending subsidiary. Hyperscale Data’s headquarters are located at 11411 Southern Highlands Parkway, Suite 190, Las Vegas, NV 89141.

On December 23, 2024, the Company issued one million (1,000,000) shares of a newly designated Series F Exchangeable Preferred Stock (the “Series F Preferred Stock”) to all common stockholders and holders of the Series C Preferred Stock on an as-converted basis. The Divestiture will occur through the voluntary exchange of the Series F Preferred Stock for shares of Class A Common Stock and Class B Common Stock of ACG (collectively, the “ACG Shares”). The Company reminds its stockholders that only those holders of the Series F Preferred Stock who agree to surrender such shares, and do not properly withdraw such surrender, in the exchange offer through which the Divestiture will occur, will be entitled to receive the ACG Shares and consequently be shareholders of ACG upon the occurrence of the Divestiture.

Forward-Looking Statements

This press release contains “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. These forward-looking statements generally include statements that are predictive in nature and depend upon or refer to future events or conditions, and include words such as “believes,” “plans,” “anticipates,” “projects,” “estimates,” “expects,” “intends,” “strategy,” “future,” “opportunity,” “may,” “will,” “should,” “could,” “potential,” or similar expressions. Statements that are not historical facts are forward-looking statements. Forward-looking statements are based on current beliefs and assumptions that are subject to risks and uncertainties.

Forward-looking statements speak only as of the date they are made, and the Company undertakes no obligation to update any of them publicly in light of new information or future events. Actual results could differ materially from those contained in any forward-looking statement as a result of various factors. More information, including potential risk factors, that could affect the Company’s business and financial results are included in the Company’s filings with the U.S. Securities and Exchange Commission, including, but not limited to, the Company’s Forms 10-K, 10-Q and 8-K. All filings are available at www.sec.gov and on the Company’s website at hyperscaledata.com.

 

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SOURCE Hyperscale Data Inc.

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In HelloNation, Financial Advisor Jennifer Prosise of Joliet, IL Breaks Down When to Start Financial Planning

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JOLIET, Ill., April 27, 2026 /PRNewswire/ — When is the right time to begin financial planning? A recent HelloNation article featuring Financial Advisor Jennifer Prosise of The Voyager Group, Ltd. in Joliet, IL, explores why early financial planning can create lasting advantages, especially during key life transitions.

 

The article challenges the common belief that financial planning only becomes necessary later in life. According to the feature, waiting until retirement planning is urgent can limit flexibility and options. By starting earlier, individuals can make gradual adjustments that align with long-term goals and reduce financial stress over time.

Jennifer Prosise explains that financial planning is most effective when it starts at the moment questions begin to surface. The article notes that planning isn’t tied to age, but to life events, such as a career change, starting a family, or returning to school. These life transitions often reshape responsibilities and future priorities, making early financial planning both timely and practical.

One of the most valuable aspects of early financial planning is habit-building. The article emphasizes how small choices about income and savings, spending, or borrowing compound over time. Establishing a structure early creates momentum and makes it easier to adapt when circumstances shift.

Career changes are a key opportunity to begin planning. With changes in income, benefits, and risk, the article advises individuals to assess how income and savings can work together more efficiently. A financial advisor can help clarify goals and offer structure during times of professional change.

For growing families, financial planning provides support when expenses increase and new needs emerge. The article points out that early planning can balance short-term decisions with long-term goals like education costs, housing needs, or lifestyle flexibility. Financial clarity during these moments reduces uncertainty and helps families prioritize with confidence.

The article also highlights how education decisions, such as starting or returning to college, can benefit from early financial planning. Loans, tuition, and long-term earnings potential all come into play. Planning in advance helps individuals evaluate tradeoffs and avoid reactive decisions that may lead to unnecessary debt.

Entrepreneurs and small business owners also find value in starting early. Business ventures bring both opportunities and risks, and financial planning helps manage both. With income fluctuations and investment decisions to weigh, early structure ensures that personal and professional goals remain aligned.

The article explains that early financial planning also creates space for gradual change. Instead of making large corrections later in life, people can make smaller, more sustainable adjustments. This flexibility supports retirement planning over a longer horizon and builds resilience during financial shifts.

Jennifer Prosise also points out the emotional benefits of planning early. With a framework in place, people are less likely to feel overwhelmed during uncertain times. Financial planning reduces confusion and allows for steady progress toward long-term goals.

When It Makes Sense to Start Financial Planning features insights from Jennifer Prosise, Financial Advisor of Joliet, IL, in HelloNation.

About HelloNation
HelloNation is a premier media platform that connects readers with trusted professionals and businesses across various industries. Through its innovative “edvertising” approach that blends educational content and storytelling, HelloNation delivers expert-driven articles that inform, inspire, and empower. Covering topics from home improvement and health to business strategy and lifestyle, HelloNation highlights leaders making a meaningful impact in their communities.

View original content to download multimedia:https://www.prnewswire.com/news-releases/in-hellonation-financial-advisor-jennifer-prosise-of-joliet-il-breaks-down-when-to-start-financial-planning-302754763.html

SOURCE HelloNation

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