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Biofidelity to launch Enspyre® technology at AGBT 2025

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Enspyre is a next generation sequencing (NGS) preparation technology enabling higher sensitivity variant calling from a fraction of the data

CAMBRIDGE, England and RESEARCH TRIANGLE PARK, N.C., Feb. 20, 2025 /PRNewswire/ — Biofidelity, a leader in innovative genomic solutions, will present launch details for Enspyre®, a novel target enrichment technology with a broad spectrum of potential applications that allows for selective enrichment of specified variants prior to sequencing.

Enspyre® technology redefines what is possible with NGS by dramatically enhancing signal to noise

“NGS is highly inefficient – with as few as one in 20 million sequenced bases resulting in a variant call. This results in poor signal to noise, severely limiting the potential of NGS that even AI will never unlock,” said Biofidelity Co-founder and CEO, Barnaby Balmforth, PhD. “Enspyre removes up to 99% of background DNA prior to sequencing, enabling high throughput NGS applications on benchtop sequencers. This cracks wide open the potential for new applications of NGS across clinical use and research science.”

Enspyre (Enrichment by selective pyrophosphorolysis and release) redefines what is possible with NGS by dramatically enhancing signal to noise, enabling the identification of variants with a sequencing depth reduced by more than 95% compared to a non-selective assay. This presents the opportunity to transform a broad spectrum of potential applications within oncology, including minimum residual disease (MRD) testing, and beyond. Additional benefits include lower data processing time and significantly decreased data storage requirements. Cumulatively, these benefits could significantly improve sensitivity, bring down the cost of sequencing necessary for MRD detection, and deliver results significantly faster for patients.

Biofidelity will present Enspyre proof of concept data at the Advances in Genome Biology and Technology (AGBT) General Meeting in Marco Island, Florida, February 23-26.

The poster (#434) entitled: Enspyre: A novel enrichment technology for selected DNA variants using pyrophosphorolysis will be presented on Tuesday, February 25, 2025 from 4:45-6:10pm EST.

Enspyre technology is complementary to Biofidelity’s PCR-based Aspyre® technology and the commercially available Aspyre® Lung product which enables fast, simple, decentralized testing for non-small cell lung cancer biomarkers in tissue and blood. Together, these two technologies enable a pipeline of products to be purpose-built to meet critical unmet needs throughout oncology. 

Biofidelity is taking an ‘Intel Inside’ approach to making Enspyre commercially available. The company is actively pursuing partnering and licensing opportunities with multiple global pharmaceutical companies, contract research organizations (CROs) and precision medicine drug developers.

To learn more about Enspyre, please visit biofidelity.com/products/enspyre

About Biofidelity
Biofidelity is a rapidly growing commercial-stage genomic technology company dedicated to improving and extending the lives of patients with cancer by enabling better targeting of therapies, early detection of treatment resistance and routine monitoring of treatment response. Visit biofidelity.com and connect with us on LinkedIn.

Contact
Andrea Conners
+1 239-728-1202
a.conners@biofidelity.com

View original content to download multimedia:https://www.prnewswire.com/news-releases/biofidelity-to-launch-enspyre-technology-at-agbt-2025-302377273.html

SOURCE Biofidelity

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Peninsula Visa Launches Comprehensive OCI Processing Services

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Peninsula Visa, a trusted leader in immigration and visa processing services with over 50 years of expertise, today announced the launch of its comprehensive Overseas Citizen of India (OCI) processing services. To celebrate this milestone, Peninsula Visa is offering new users an exclusive 20% discount with promo code OCI20 at checkout.

SAN JOSE, Calif., May 3, 2026 /PRNewswire-PRWeb/ — Peninsula Visa, a trusted leader in immigration and visa processing services with over 50 years of expertise, today announced the launch of its comprehensive Overseas Citizen of India (OCI) processing services. To celebrate this milestone, Peninsula Visa is offering new users an exclusive 20% discount with promo code OCI20 at checkout.

For 50 years, Peninsula Visa has helped families navigate immigration. OCI processing is one of our most impactful services, connecting the Indian diaspora to their heritage. We’re proud to bring our expertise to help families secure OCI status with confidence. Evan James, CEO

A Full Suite of OCI Services

Peninsula Visa’s OCI services cover every stage of the OCI lifecycle, ensuring that members of the Indian diaspora receive expert support from start to finish.

The four service types now available are:

New OCI Application — For foreign nationals of Indian origin, spouses of Indian citizens or existing OCI card holders, and minor children with at least one Indian parent applying for OCI status for the first time.OCI Card Renewal — For card holders whose OCI card has expired, or whose linked passport has been renewed or replaced and requires an updated booklet.Re-issuance (Age Milestones) — OCI cards must be re-issued when minors reach the age of 18 and again when card holders turn 50, due to significant changes in appearance. Peninsula Visa guides clients through both transitions seamlessly.Miscellaneous OCI Services — Covering corrections to existing records, lost or damaged card replacement, address changes, and other administrative updates to the OCI file.

Why Choose Peninsula Visa for Your OCI Application

Peninsula Visa brings decades of institutional knowledge and a client-first philosophy to every OCI case.

Key value propositions include:

Expert Guidance — Dedicated OCI specialists with deep knowledge of consulate requirements, eligibility rules, and documentation standards across all service types.High Approval Rate — A meticulous multi-stage review process that identifies and resolves issues before submission, dramatically reducing the likelihood of rejection or delay.Fast Turnaround — Standard processing in 12-15 Business Days for most OCI service types, with real-time status updates throughout the process.End-to-End Support — Personalized document checklists, secure document uploads, expert form preparation, consulate submission, and post-submission tracking — all in one place.

Launch Promotion

Save 20% on any OCI service — new users only

OCI20

Enter code OCI20 at checkout. Available to new users. No expiration date.

Leadership Perspective

“For 50 years, Peninsula Visa has helped individuals and families navigate the complexities of immigration documentation. OCI processing is one of the most impactful services we have ever added — it directly connects the Indian diaspora to their heritage country in a lasting, meaningful way. We are proud to bring our proven expertise and client-centric approach to this important service, and we look forward to helping thousands of families secure their OCI status with confidence.”

Founded in 1975, Peninsula Visa has built its reputation on precision, transparency, and a genuine commitment to client outcomes. The addition of OCI processing services reflects the company’s ongoing mission to expand its offerings to meet the evolving needs of immigrants and their families across the United States.

Get Started Today

Eligible applicants can begin their OCI journey by visiting Peninsula Visa’s dedicated OCI Services page. New users can take advantage of the 20% launch discount by entering promo code OCI20 at checkout when selecting any OCI service type.

Media Contact

Evan James, Peninsula Visa, 1 4087277515, media@peninsulavisa.com, https://peninsulavisa.com/

View original content to download multimedia:https://www.prweb.com/releases/peninsula-visa-launches-comprehensive-oci-processing-services-302760544.html

SOURCE Peninsula Visa

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Peninsula Visa Launches Comprehensive OCI Processing Services

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on

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Peninsula Visa, a trusted leader in immigration and visa processing services with over 50 years of expertise, today announced the launch of its comprehensive Overseas Citizen of India (OCI) processing services. To celebrate this milestone, Peninsula Visa is offering new users an exclusive 20% discount with promo code OCI20 at checkout.

SAN JOSE, Calif., May 3, 2026 /PRNewswire-PRWeb/ — Peninsula Visa, a trusted leader in immigration and visa processing services with over 50 years of expertise, today announced the launch of its comprehensive Overseas Citizen of India (OCI) processing services. To celebrate this milestone, Peninsula Visa is offering new users an exclusive 20% discount with promo code OCI20 at checkout.

For 50 years, Peninsula Visa has helped families navigate immigration. OCI processing is one of our most impactful services, connecting the Indian diaspora to their heritage. We’re proud to bring our expertise to help families secure OCI status with confidence. Evan James, CEO

A Full Suite of OCI Services

Peninsula Visa’s OCI services cover every stage of the OCI lifecycle, ensuring that members of the Indian diaspora receive expert support from start to finish.

The four service types now available are:

New OCI Application — For foreign nationals of Indian origin, spouses of Indian citizens or existing OCI card holders, and minor children with at least one Indian parent applying for OCI status for the first time.OCI Card Renewal — For card holders whose OCI card has expired, or whose linked passport has been renewed or replaced and requires an updated booklet.Re-issuance (Age Milestones) — OCI cards must be re-issued when minors reach the age of 18 and again when card holders turn 50, due to significant changes in appearance. Peninsula Visa guides clients through both transitions seamlessly.Miscellaneous OCI Services — Covering corrections to existing records, lost or damaged card replacement, address changes, and other administrative updates to the OCI file.

Why Choose Peninsula Visa for Your OCI Application

Peninsula Visa brings decades of institutional knowledge and a client-first philosophy to every OCI case.

Key value propositions include:

Expert Guidance — Dedicated OCI specialists with deep knowledge of consulate requirements, eligibility rules, and documentation standards across all service types.High Approval Rate — A meticulous multi-stage review process that identifies and resolves issues before submission, dramatically reducing the likelihood of rejection or delay.Fast Turnaround — Standard processing in 12-15 Business Days for most OCI service types, with real-time status updates throughout the process.End-to-End Support — Personalized document checklists, secure document uploads, expert form preparation, consulate submission, and post-submission tracking — all in one place.

Launch Promotion

Save 20% on any OCI service — new users only

OCI20

Enter code OCI20 at checkout. Available to new users. No expiration date.

Leadership Perspective

“For 50 years, Peninsula Visa has helped individuals and families navigate the complexities of immigration documentation. OCI processing is one of the most impactful services we have ever added — it directly connects the Indian diaspora to their heritage country in a lasting, meaningful way. We are proud to bring our proven expertise and client-centric approach to this important service, and we look forward to helping thousands of families secure their OCI status with confidence.”

Founded in 1975, Peninsula Visa has built its reputation on precision, transparency, and a genuine commitment to client outcomes. The addition of OCI processing services reflects the company’s ongoing mission to expand its offerings to meet the evolving needs of immigrants and their families across the United States.

Get Started Today

Eligible applicants can begin their OCI journey by visiting Peninsula Visa’s dedicated OCI Services page. New users can take advantage of the 20% launch discount by entering promo code OCI20 at checkout when selecting any OCI service type.

Media Contact

Evan James, Peninsula Visa, 1 4087277515, media@peninsulavisa.com, https://peninsulavisa.com/

View original content to download multimedia:https://www.prweb.com/releases/peninsula-visa-launches-comprehensive-oci-processing-services-302760544.html

SOURCE Peninsula Visa

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Booking.com’s Latest Travel and Sustainability Research Reveals Australian Generational Paradox

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SYDNEY, May 4, 2026 /PRNewswire/ — Today Booking.com released its 11th annual research report into consumer attitudes and understanding of the social and environmental impact of travel. With insights from 32,500 travellers across 35 markets globally, including 1,000 from Australia, this year’s research highlights a generational paradox.

While 83% of Australian travellers say that more sustainable travel is important to them, older generations demonstrate greater commitment through concrete actions, despite younger generations often expressing stronger sustainability intentions.

Older generations demonstrate greater commitment through concrete sustainable actions, with almost two–thirds of Boomers across Asia Pacific (63%) saying they will shop more at local, independent stores on their trips, three–quarters (75%) planning to reduce general waste, and 63% intending to reduce energy consumption, higher than Gen X, Millennials and Gen Z.However, younger travellers are leading in cultural and conservation management; more than a quarter of Gen Z (27%) and Millennials (26%) participated in a tour or activity that contributed to the health or conservation of the local ecosystem or wildlife.Extreme weather is actively reshaping travel choices. Nearly three-quarters of Australian travellers said they consider extreme weather risk when choosing both destination (72%), and timing (75%), and 27% reported having cancelled or changed trip plans in the past twelve months due to extreme weather or natural disaster.Australian travellers are shifting when and where they travel, seeking reliable climates and comfort. 43% say they plan to avoid overcrowded tourist destinations, 42% plan to travel outside of peak season, and 26% will seek out destinations with cooler temperatures.In 2025, travellers booked more than 100 million room nights on Booking.com at accommodation partners with a third-party sustainability certification, including at 363 third-party certified Australian properties.

To find Booking.com’s full 2026 research, visit here.

 

View original content:https://www.prnewswire.com/apac/news-releases/bookingcoms-latest-travel-and-sustainability-research-reveals-australian-generational-paradox-302760310.html

SOURCE Booking.com

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