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Biofidelity to launch Enspyre® technology at AGBT 2025

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Enspyre is a next generation sequencing (NGS) preparation technology enabling higher sensitivity variant calling from a fraction of the data

CAMBRIDGE, England and RESEARCH TRIANGLE PARK, N.C., Feb. 20, 2025 /PRNewswire/ — Biofidelity, a leader in innovative genomic solutions, will present launch details for Enspyre®, a novel target enrichment technology with a broad spectrum of potential applications that allows for selective enrichment of specified variants prior to sequencing.

Enspyre® technology redefines what is possible with NGS by dramatically enhancing signal to noise

“NGS is highly inefficient – with as few as one in 20 million sequenced bases resulting in a variant call. This results in poor signal to noise, severely limiting the potential of NGS that even AI will never unlock,” said Biofidelity Co-founder and CEO, Barnaby Balmforth, PhD. “Enspyre removes up to 99% of background DNA prior to sequencing, enabling high throughput NGS applications on benchtop sequencers. This cracks wide open the potential for new applications of NGS across clinical use and research science.”

Enspyre (Enrichment by selective pyrophosphorolysis and release) redefines what is possible with NGS by dramatically enhancing signal to noise, enabling the identification of variants with a sequencing depth reduced by more than 95% compared to a non-selective assay. This presents the opportunity to transform a broad spectrum of potential applications within oncology, including minimum residual disease (MRD) testing, and beyond. Additional benefits include lower data processing time and significantly decreased data storage requirements. Cumulatively, these benefits could significantly improve sensitivity, bring down the cost of sequencing necessary for MRD detection, and deliver results significantly faster for patients.

Biofidelity will present Enspyre proof of concept data at the Advances in Genome Biology and Technology (AGBT) General Meeting in Marco Island, Florida, February 23-26.

The poster (#434) entitled: Enspyre: A novel enrichment technology for selected DNA variants using pyrophosphorolysis will be presented on Tuesday, February 25, 2025 from 4:45-6:10pm EST.

Enspyre technology is complementary to Biofidelity’s PCR-based Aspyre® technology and the commercially available Aspyre® Lung product which enables fast, simple, decentralized testing for non-small cell lung cancer biomarkers in tissue and blood. Together, these two technologies enable a pipeline of products to be purpose-built to meet critical unmet needs throughout oncology. 

Biofidelity is taking an ‘Intel Inside’ approach to making Enspyre commercially available. The company is actively pursuing partnering and licensing opportunities with multiple global pharmaceutical companies, contract research organizations (CROs) and precision medicine drug developers.

To learn more about Enspyre, please visit biofidelity.com/products/enspyre

About Biofidelity
Biofidelity is a rapidly growing commercial-stage genomic technology company dedicated to improving and extending the lives of patients with cancer by enabling better targeting of therapies, early detection of treatment resistance and routine monitoring of treatment response. Visit biofidelity.com and connect with us on LinkedIn.

Contact
Andrea Conners
+1 239-728-1202
a.conners@biofidelity.com

View original content to download multimedia:https://www.prnewswire.com/news-releases/biofidelity-to-launch-enspyre-technology-at-agbt-2025-302377273.html

SOURCE Biofidelity

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Achieve named to Az Business Magazine’s ’10 Best Places for Women to Work in Arizona’ for 2026

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Recognition highlights the company’s commitment to creating opportunities for women to grow and lead

SAN MATEO, Calif., July 23, 2026 /PRNewswire/ — Achieve, the leader in digital personal finance, has been named among the 2026 10 Best Places for Women to Work in Arizona by Az Business Magazine. The annual recognition highlights organizations that create supportive environments where women can thrive professionally, advance into leadership roles and build meaningful careers.

The honor reflects Achieve’s ongoing investment in workplace programs that support employee growth, flexibility, leadership development and career advancement. Women serve in leadership roles across the organization and play a critical role in shaping the company’s culture, products and long-term success.

“Creating an environment where women can grow, lead and build rewarding careers is central to who we are as a company,” said Achieve Senior Vice President of Human Resources Heather Marcom. “We’re honored to be recognized among Arizona’s top workplaces for women and remain committed to fostering a culture where employees feel supported, valued and empowered to do their best work.”

Achieve maintains a major corporate presence in the Phoenix area, where hundreds of employees contribute to the company’s mission of helping people move from struggling to thriving financially. The company supports employees through leadership development opportunities, employee resource groups, mentorship and learning programs designed to help team members reach their professional goals.

The recognition adds to a growing list of workplace honors for Achieve. Earlier this year, the company was named among the Top 3 Best Workplaces for LGBTQ+ Employees by BestCompaniesAZ and was also recognized by AZ Big Media as one of Arizona’s Most Admired Companies.

“Strong organizations are built by diverse perspectives and inclusive leadership,” said Marcom. “We’re proud of the talented women across Achieve who help drive our business forward every day and grateful for the impact they make on our employees, customers and communities.”

The 10 Best Places for Women to Work in Arizona list is determined through a public voting process conducted by AZ Big Media and published in Az Business magazine.

About Achieve

Achieve, THE digital personal finance company, helps everyday people get on, and stay on, the path to a better financial future. Achieve pairs proprietary data and analytics with personalized support to offer personal loanshome equity loans, debt relief and debt consolidation, along with financial tips and education and free mobile apps: Achieve MoLO® (Money Left Over) and Achieve GOOD™ (Get Out Of Debt). Achieve is frequently recognized for providing top-rated customer experience and satisfaction by both consumers and leading personal finance review platforms and has 2,200 dedicated teammates across the country, with hubs in Arizona, California, Florida and Texas.

Achieve refers to the global organization and may denote one or more affiliates of Achieve Company, including Achieve.com, Equal Housing Opportunity (NMLS ID #138464); Achieve Home Loans, Equal Housing Opportunity (NMLS ID #1810501); Achieve Personal Loans (NMLS ID #227977); Freedom Debt Relief (NMLS ID # 1248929); and Freedom Financial Asset Management (CRD #170229).

Contacts

Austin Kilgore
akilgore@achieve.com
214-908-5097

Elina Tarkazikis
etarkazikis@achieve.com

View original content to download multimedia:https://www.prnewswire.com/news-releases/achieve-named-to-az-business-magazines-10-best-places-for-women-to-work-in-arizona-for-2026-302833720.html

SOURCE Achieve

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National Press Club Statement on the withdrawal of subpoenas targeting New York Times journalists

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WASHINGTON, July 23, 2026 /PRNewswire/ — National Press Club President Mark Schoeff Jr. released the following statement:

“The Justice Department’s decision to withdraw subpoenas targeting journalists at The New York Times is a welcome and necessary step to protect the public’s constitutional right to an independent press.

These subpoenas should never have been issued in the first place. Compelling journalists to reveal confidential sources sends a chilling message to those who seek to inform the public and threatens the very foundation of press freedom.

Every American should understand what is at stake when the government turns its investigative powers on journalists. It is not routine. It is an extraordinary intrusion that strikes at the heart of the First Amendment and your right to information about your government.

The greatest danger was not the subpoenas themselves, but the message they sent: That sources could be exposed, that whistleblowers should remain silent, and that the American people might know less about the actions of their own government.

A strong democracy depends on a press that can report freely, hold power to account, and inform the public without intimidation.

We urge continued vigilance to ensure that journalists can do their jobs without interference and that protections for source confidentiality are upheld consistently.”

About the National Press Club

Founded in 1908, the National Press Club is the world’s leading professional organization for journalists and a leading voice for press freedom in the U.S. and worldwide.

Contact: Beth Francesco, Executive Director of the National Press Club Journalism Institute, media@press.org

View original content to download multimedia:https://www.prnewswire.com/news-releases/national-press-club-statement-on-the-withdrawal-of-subpoenas-targeting-new-york-times-journalists-302833722.html

SOURCE National Press Club

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NCC Launches NCC Connect™ to Put Credit, Fraud, and Compliance Inside the CRM Dealers Already Use

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A powerful new solution that embeds credit access, fraud detection, and compliance directly into the dealership’s existing CRM — removing the system-switching that slows deals and exposes dealers to risk.

AUSTIN, Texas, July 23, 2026 /PRNewswire-PRWeb/ — NCC, a leading provider of credit and compliance solutions for automotive dealerships, today announced the launch of NCC Connect™, a powerful platform that runs credit, fraud, and compliance from inside the CRM a dealership already uses — without friction or duplicate entry.

“Dealers don’t need another system to log into,” said Brian Skutta, President and CEO of NCC. “They need the tools they already have to work better together. NCC Connect puts credit, fraud detection, and compliance right where the team already works — inside the CRM they use every day.”

“Dealers don’t need another system to log into,” said Brian Skutta, President and CEO of NCC. “They need the tools they already have to work better together. NCC Connect puts credit, fraud detection, and compliance right where the team already works — inside the CRM they use every day.”

As deals grow more complex and fraud more sophisticated, dealers are juggling more disconnected systems than ever — the CRM, the credit system, the compliance tools — switching between them on every transaction. Each switch breaks momentum, invites a skipped step, and slows the path to funding. NCC Connect meets this moment with a single, seamless solution that keeps the full credit, fraud, and compliance engine right where the team already works.

Why NCC Connect Matters Right Now

Dealers lose time and margin switching between the CRM, credit, and compliance systems on every dealAuto lending fraud continues to climb, with industry fraud exposure reaching a record $10.4 billion in 2025, according to Point Predictive’s 2026 Auto Lending Fraud Trends ReportState compliance is tightening, with laws like California’s SB 766 (CARS Act) taking effect October 1, 2026Every disconnected step is another chance for an error, a delay, or a deal that stalls before funding

These pressures are forcing dealers to consolidate, and NCC Connect delivers the edge.

Product Highlights:

Inside the CRM — Soft-pull and hard credit access from all three major bureaus — Experian, TransUnion, and Equifax — without leaving the workflowFraud & Identity Built In — Identity verification and synthetic fraud detection delivered within the credit pull, flagging Red Flag conditions before the deal moves to fundingCompliance on Autopilot — FCRA and FTC controls with automatic, audit-ready documentation stored in the deal record99.99% Uptime — The industry’s highest, so the platform is there when a deal is on the desk

NCC Connect runs soft-pull pre-qualifications and hard credit pulls from any bureau or score model without leaving the CRM, while customer data stays inside the existing CRM structure. Every credit, fraud, and compliance result is captured on the deal record — giving dealers a single, audit-ready source of truth and a faster, cleaner path to funding.

NCC Connect extends the same powerful, credit-first engine behind NCC’s Complete Credit™ platform into the CRM where dealers already work. For dealers, that means more approvals, stronger fraud protection, and faster funding, without changing how the team works.

Learn more about NCC Connect at https://nccdirect.com/ncc-connect/

About NCC:

With offices in Austin, TX, Bettendorf, IA, and Las Vegas, NV, NCC has been a trusted partner in credit-driven retailing for automotive dealerships for nearly three decades. We combine a powerful credit and compliance engine with a fully integrated Desking platform to drive maximum profitability. Our focus on innovation, user-friendly products, and dependable systems — supported by a dedicated account management team — has solidified our reputation as a leader in the industry. www.nccdirect.com

Media Contact

Holly Smith, NCC, 1 8285732722, hsmith@nccdirect.com, https://nccdirect.com/

View original content:https://www.prweb.com/releases/ncc-launches-ncc-connect-to-put-credit-fraud-and-compliance-inside-the-crm-dealers-already-use-302832007.html

SOURCE NCC

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