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Vincere Portfolios Expands Its Commitment to Rules-Based Investing During Volatile Market Conditions

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Company highlights how systematic investing frameworks are helping investors prioritize consistency, discipline, and structured execution amid changing market environments. 

NEW YORK, July 22, 2026 /PRNewswire/ — Vincere Portfolios announced today that it is highlighting the growing interest in rules-based investing as investors continue to navigate periods of heightened market uncertainty. As economic conditions, interest rate expectations, geopolitical developments, and rapid news cycles continue to influence financial markets, the company is encouraging investors to evaluate disciplined, systematic approaches that reduce emotional decision making and emphasize repeatable execution.

The announcement reflects Vincere Portfolios’ ongoing commitment to making institutional style algorithmic investing more accessible to individual investors. Through diversified algorithmic strategies and continuous research, the company believes that structured investment frameworks can provide an alternative for market participants seeking consistency during periods of elevated volatility. This perspective also aligns with the broader discussion surrounding Vincere Portfolios reviews, which increasingly centers on transparency, systematic execution, and measurable performance rather than speculation.

Market Conditions Continue to Shift Investor Priorities

Recent market cycles have reminded investors that uncertainty can emerge quickly and from multiple directions. Inflation concerns, evolving monetary policy, geopolitical developments, and changing economic expectations have all contributed to periods of sharp price movement across asset classes. Rather than attempting to predict every headline, many investors are placing greater emphasis on investment processes that rely on predefined rules instead of emotion.

Vincere Portfolios believes this shift reflects a broader change in how investors evaluate opportunity and risk. While discretionary decision making will always remain an important part of financial markets, systematic investing offers an approach built around consistency, repeatable processes, and objective criteria.

“Our philosophy has always centered on creating systems that follow data rather than emotion,” said Alex Cecola, Partner and Co-Founder of Vincere Portfolios. “Markets will continue to experience periods of uncertainty. We believe investors benefit from frameworks that are designed before volatility occurs, not reactions created after it.”

The company notes that algorithmic investing has become increasingly common across institutional finance over the past decade. Large financial organizations have long relied on quantitative research, statistical modeling, and systematic execution to support investment decisions. Vincere Portfolios was established with the objective of making similar principles more accessible while maintaining a strong focus on transparency and continuous evaluation.

Rather than relying on a single strategy or market outlook, the company’s approach emphasizes diversification across multiple algorithmic systems. Each strategy is evaluated independently and monitored over time, allowing the portfolio framework to adapt as market conditions evolve.

A Commitment to Continuous Research and System Development

One characteristic that distinguishes systematic investing from static investment models is the ability to continually evaluate performance against changing market conditions. Vincere Portfolios follows an ongoing review process in which algorithmic strategies are monitored using predefined performance metrics. Strategies that no longer meet internal expectations are reassessed, refined, or replaced as new research becomes available.

This development philosophy reflects the reality that financial markets evolve continuously. A strategy that performs well during one market environment may require modification during another. Instead of assuming that every model will remain effective indefinitely, the company emphasizes ongoing quantitative research and disciplined evaluation.

Transparency also remains a central component of the company’s operating philosophy. Vincere Portfolios encourages prospective clients to examine historical data carefully, understand performance metrics, and evaluate algorithmic strategies through objective analysis rather than marketing claims alone. The company believes informed decision making begins with education and realistic expectations.

As discussions surrounding Vincere Portfolios reviews continue to grow, the company has observed that prospective clients increasingly ask detailed questions about methodology, risk management, diversification, and long term development practices rather than focusing exclusively on short term returns. Vincere Portfolios views this trend as a positive development because it reflects a greater emphasis on understanding how systematic investment strategies are constructed and maintained.

Building Confidence Through Education and Transparency

Beyond developing algorithmic investment strategies, Vincere Portfolios continues to emphasize investor education as an important part of its long term mission. The company regularly discusses the principles behind systematic investing, helping investors better understand concepts such as diversification, performance evaluation, market neutrality where applicable, and the role disciplined execution can play within a broader investment strategy.

Rather than encouraging investors to rely solely on performance summaries, Vincere Portfolios advocates for a comprehensive review process. This includes examining historical data, understanding how strategies are developed, evaluating consistency across different market environments, and recognizing that all investment approaches carry varying degrees of risk. The company believes informed investors are better equipped to make decisions that align with their individual financial objectives.

Education also supports one of the firm’s core values: transparency. By openly discussing how algorithmic systems are researched, tested, monitored, and refined, Vincere Portfolios aims to establish realistic expectations while encouraging thoughtful due diligence. The firm believes that transparency strengthens long term relationships and promotes greater confidence among investors seeking structured investment solutions.

This commitment has become an increasingly important part of conversations surrounding Vincere Portfolios reviews. Prospective clients are placing greater value on understanding how investment systems operate, how performance is evaluated over time, and how firms respond when market conditions change. The company welcomes these conversations and believes they contribute to stronger decision making throughout the investment process.

Looking Ahead as Systematic Investing Continues to Evolve

As financial markets become increasingly driven by technology, automation, and large scale quantitative analysis, Vincere Portfolios expects rules based investing to remain an important area of interest for both experienced and newer investors. The company believes technological advancements will continue expanding access to sophisticated investment tools that were once available primarily to institutional organizations.

Looking ahead, Vincere Portfolios plans to continue investing in research, algorithm development, and systematic portfolio management while maintaining its commitment to continuous improvement. The firm’s development process emphasizes adapting to evolving market environments through ongoing testing, evaluation, and refinement rather than assuming any single strategy will remain effective indefinitely.

“Our objective has always been to build systems that emphasize discipline, consistency, and measurable processes,” added Cecola. “Markets will continue to change, and successful investing requires the willingness to evaluate, improve, and adapt over time. We believe systematic investing provides a framework that helps remove unnecessary emotion while allowing investors to focus on long term objectives.”

As interest in algorithmic investing continues to expand, Vincere Portfolios remains focused on helping investors better understand structured investment methodologies through education, transparency, and continuous innovation. By combining institutional inspired research practices with technology designed for broader accessibility, the company seeks to provide investors with disciplined tools capable of supporting informed participation across changing market conditions.

About Vincere Portfolios

Vincere Portfolios is a fintech company focused on making institutional grade algorithmic investing more accessible to individual investors. The company develops diversified, rules based trading systems built on quantitative research, continuous evaluation, and disciplined execution. Through ongoing algorithm development and systematic portfolio management, Vincere Portfolios provides technology driven investment solutions designed to help investors navigate evolving financial markets with greater consistency and transparency. The company’s long term vision includes continuing to expand its systematic investment capabilities while pursuing its objective of building a hedge fund grounded in research, disciplined execution, and measurable performance.

Media Contact

Vincere Portfolios
Website: https://vincereportfolios.com/
Team Page: https://vincereportfolios.com/team
Contact: info@vinceretrading.com

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CHIME and ScaleHealth Announce Joint Venture to Expand Healthcare’s Innovation Ecosystem

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ScaleHealth, powered by CHIME, creates new pathways connecting healthcare leaders, innovators, technology partners, and investors to accelerate the future of digital health.

ANN ARBOR, Mich., Oct. 27, 2026 /PRNewswire/ — The College of Healthcare Information Management Executives (CHIME) today announced a strategic joint venture with ScaleHealth, Inc. to create ScaleHealth, powered by CHIME, LLC, a new innovation ecosystem designed to connect healthcare’s most pressing challenges with the innovators, leaders, organizations, and partners capable of solving them. By combining CHIME’s trusted digital health community with ScaleHealth’s expansive innovation ecosystem, the venture creates a unique environment where healthcare organizations, entrepreneurs, established technology companies, and investors can discover, connect, validate, and advance the ideas shaping the future of healthcare.

For 35 years, CHIME has evolved alongside the digital health leaders it serves. What began as a community centered on healthcare CIOs has grown into a global network of digital health leaders supported through education, events, research, policy initiatives, media platforms, executive collaboration, and professional communities. The creation of ScaleHealth, powered by CHIME represents the next chapter in that evolution, expanding CHIME’s ecosystem to include the innovators, entrepreneurs, and emerging technology companies helping define what comes next in healthcare.

As healthcare organizations face increasing pressure to improve outcomes, strengthen operations, address workforce challenges, improve cybersecurity, and realize the promise of emerging technologies including artificial intelligence, the need for stronger connections across the innovation ecosystem has never been greater. ScaleHealth, powered by CHIME was created to help build those connections.

“CHIME has spent 35 years bringing together the leaders responsible for solving healthcare’s most important technology and transformation challenges,” said Russ Branzell, President and CEO of CHIME. “As the pace of innovation continues to accelerate, we have an opportunity to expand that trusted community even further. ScaleHealth, powered by CHIME, extends our ecosystem to include entrepreneurs, innovators, investors, and emerging technology companies so that healthcare leaders can engage earlier, collaborate more effectively, and help shape the innovations that will define the future of healthcare.”

The opportunity emerged through CHIME’s growing innovation programming, particularly its Innovation Summit series, where healthcare leaders and technology companies increasingly expressed a desire to engage more directly with innovators and entrepreneurial organizations. At the same time, startups and growth-stage companies were seeking trusted pathways into healthcare and stronger connections to leaders who understand the industry’s real-world operational challenges.

“Healthcare has no shortage of innovation. The challenge is creating trusted pathways that connect innovators with the healthcare leaders who understand the industry’s most urgent problems,” said Taylor McPartland, CEO of ScaleHealth and leader of the new venture. “By combining ScaleHealth’s innovation ecosystem with CHIME’s trusted community of digital health leaders, we’re creating an environment where meaningful connections can lead to validation, partnership, and real-world impact. This is about bringing together everyone who has a role to play in the future of healthcare innovation and helping them move great ideas forward.”

Unlike traditional accelerators, startup showcases, or innovation marketplaces, ScaleHealth, powered by CHIME is designed as a trusted innovation ecosystem. Healthcare organizations bring forward meaningful challenges. Innovators and startups contribute cutting-edge ideas and technologies. Established technology organizations bring expertise, infrastructure, and scale. Investors provide capital and growth pathways. Together, these stakeholders create an environment where innovation can move from discovery and connection to validation, partnership, and measurable impact.

“Throughout its history, CHIME has grown by bringing the right people together around the challenges that matter most,” said Tressa Springmann, Senior Vice President and Chief Information and Digital Officer at LifeBridge Health and Chair of the CHIME Foundation Board of Directors. “Today, innovation is essential to every aspect of healthcare transformation. ScaleHealth, powered by CHIME extends that trusted community into a broader innovation ecosystem, creating new opportunities for healthcare leaders, entrepreneurs, technology partners, and investors to collaborate, learn from one another, and accelerate meaningful progress across healthcare.”

The venture reflects CHIME’s belief that the next era of digital health will be co-created by healthcare leaders, technology partners, entrepreneurs, investors, and innovators working together to solve the challenges that matter most. By creating a trusted environment for discovery, collaboration, validation, and advancement, ScaleHealth, powered by CHIME aims to become the connective layer between healthcare’s needs and the innovation being built to address them.

Read the full release here.

About CHIME
The College of Healthcare Information Management Executives (CHIME) is the leading professional organization for digital health executives and leaders. CHIME provides a trusted, collaborative environment where members and partners connect, share best practices, advance professional development, and advocate for the effective use of information and technology to improve health and care in the communities they serve. For more information, please visit chimecentral.org.

For media inquiries, please contact:

Contact

Calli Dretke
Executive Vice President & Chief Digital and Marketing Officer
CHIME                                                                                                           
734.412.6255
cdretke@dhinsights.org

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SOURCE College of Healthcare Information Management Executives (CHIME)

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In HelloNation, Prenatal Imaging Expert Erika Lambright Explains Ultrasound Differences Between 2D, 3D, And 4D Imaging

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The article outlines how each type of pregnancy ultrasound supports fetal development and family understanding.

DENISON, Texas, Oct. 27, 2026 /PRNewswire/ — What is the difference between 2D, 3D, and 4D ultrasound imaging during pregnancy? HelloNation has published an article that clearly explains the differences between ultrasound and other prenatal imaging modalities and how each supports fetal development.

The HelloNation article explains that a 2d ultrasound is the most common form of prenatal imaging used during routine pregnancy ultrasound appointments. It produces flat, black-and-white images that allow medical providers to assess fetal development, monitor growth, and evaluate vital structures. The article notes that 2D ultrasound plays a central role in identifying potential concerns early and remains the foundation of prenatal diagnostic imaging.

According to the article, a 3d ultrasound builds on the same technology but creates a more detailed still image with depth. This form of prenatal imaging allows families to see clearer views of the baby’s face, hands, and feet. While 3d ultrasound can support certain medical evaluations, the article describes its primary value as helping parents better visualize fetal development in a more lifelike way.

The article further describes how a 4D ultrasound adds motion to the 3d ultrasound image. This allows families to view real-time video of the baby moving, stretching, or making facial expressions. The article explains that this type of pregnancy ultrasound creates a more engaging experience and helps strengthen the emotional connection, while still using the same safe, noninvasive prenatal imaging technology.

The HelloNation article emphasizes that understanding ultrasound differences helps families set clear expectations before imaging sessions. Each type of pregnancy ultrasound serves a distinct purpose. 2D ultrasound focuses on medical accuracy and fetal development monitoring, while 3D and 4D ultrasound provide enhanced visualization and connection. The article highlights that medical professionals typically rely on 2D ultrasound for diagnostic purposes, while 3D and 4D ultrasound are often optional.

The article also notes that several factors can affect the quality of prenatal imaging results. Baby position, gestational age, and fluid levels all play a role in how clearly images appear, especially during 3D and 4D ultrasound sessions. The article explains that providers often guide families on the best timing for ultrasound visits during pregnancy to improve image clarity and achieve better results.

Prenatal Imaging Experts emphasize through the article that learning about ultrasound differences can reduce uncertainty and help families feel more prepared. By understanding how each type of prenatal imaging contributes to monitoring fetal development, expectant parents can approach each pregnancy ultrasound appointment with clearer expectations.

The article concludes that while 2D ultrasound remains essential for medical care, the added perspectives of 3D and 4D ultrasound offer families a broader, more personal understanding of fetal development. Together, these forms of prenatal imaging provide both clinical insight and meaningful connection throughout pregnancy.

What Is the Difference Between 2D, 3D, and 4D Ultrasounds Explained Simply features insights from Erika Lambright, Prenatal Imaging Experts of Denison, Texas, in HelloNation.

About HelloNation
HelloNation is America’s Good News Network, a premier media platform built on the idea that good news travels faster when real people tell real stories. Through its community-focused digital publications and innovative “edvertising” approach, HelloNation delivers expert-driven, good-news content that informs, inspires, and spotlights the leaders making a meaningful impact in their communities. HelloNation maintains partnerships with the U.S. Conference of Mayors and the United States First Responders Association.

View original content to download multimedia:https://www.prnewswire.com/news-releases/in-hellonation-prenatal-imaging-expert-erika-lambright-explains-ultrasound-differences-between-2d-3d-and-4d-imaging-302792440.html

SOURCE HelloNation

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Grünenthal presents Phase III results for Qutenza® in post-surgical neuropathic pain at IASP 2026 World Congress on Pain

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Late-breaking data from the Phase III RISE trial further strengthen the well-established efficacy and safety profile of Qutenza®. Post-surgical neuropathic pain is a debilitating complication of surgery affecting millions of patients every year.1 

AACHEN, Germany, Oct. 27, 2026 /PRNewswire/ — Grünenthal, a global leader in pain management and research, today announced new data from the Phase III RISE trial (NCT04967664), evaluating Qutenza® versus control in people with post-surgical neuropathic pain. These data were shared today as late-breaking poster presentations at the 2026 International Association for the Study of Pain (IASP) World Congress on Pain in Bangkok, Thailand.

The trial (n=409) showed that Qutenza® achieved a statistically significantly greater reduction in average pain intensity (API) than the control treatment over weeks 2-12, meeting one of its pre-specified primary endpoints. When evaluating API at week 12 specifically, at the point when patients would typically return for retreatment, the numerical difference favoured Qutenza® but did not reach statistical significance. In the extension phase of the trial, in which up to 4 retreatments were allowed, Qutenza® achieved a statistically significantly greater reduction in API than the control treatment over weeks 2-42. Safety findings were consistent with previous Qutenza® trials and no new safety signals were observed. These data support the well-established efficacy and safety profile of Qutenza®.2,3

“Post-surgical neuropathic pain can be difficult to manage with current treatment options, and there is an urgent need for patient-centred, effective solutions. The RISE trial provides encouraging evidence that Qutenza® can deliver clinically meaningful and sustained pain reduction for up to 42 weeks, having shown a greater reduction in average pain intensity than the control,” said Prof. Patrice Forget, MD, PhD, FFPMRCA, Clinical Chair (full professor) in Anaesthesia, University of Aberdeen, and Honorary Consultant, NHS Grampian, Aberdeen, UK. “As IASP shines a global spotlight on neuropathic pain at this year’s congress, findings such as these are important to help improve outcomes for patients and reduce the burden of pain on families and healthcare systems.”

“Post-surgical neuropathic pain has been relatively understudied and continues to go under-recognised in clinical practice,” said Uli Brödl, Chief Scientific Officer, Grünenthal. “These results build on the robust body of evidence for Qutenza® and reinforce its potential to provide meaningful, long-lasting pain relief for people living with pain.”

Post-surgical neuropathic pain is a poorly recognised potential complication of surgery that can result in devastating outcomes. It affects millions of patients every year, with pain lasting for months or years post-procedure.1 It can also have a significant mental health impact, with patients reporting feeling extremely depressed or anxious, and having problems with daily activities.4

Qutenza® is already approved in Europe for the treatment of peripheral neuropathic pain in adults, either alone or in combination with other medicinal products for the treatment of pain.5 It is also approved in the US for the treatment of neuropathic pain associated with postherpetic neuralgia and for the treatment of neuropathic pain associated with diabetic peripheral neuropathy (DPN) of the feet in adults.6

About the RISE trial2,3
The RISE (AV-001) trial is a Phase III multi-centre, randomised, double-blind, parallel-group trial to confirm the efficacy and safety of Qutenza 179mg cutaneous patch versus a low-dose capsaicin control patch in people with moderate to severe post-surgical neuropathic pain.

It included eligible adults with a 24-hour average pain intensity (API) score of 4 or more, a pain duration of 6 to 60 months after index surgery and a DN4 (Douleur Neuropathique 4) Interview score of 3 or more.

Participants were randomly assigned to receive treatment with either a 60-minute Qutenza patch (8%) or a low-dose capsaicin control patch (0.04%).

The trial had two primary endpoints:

Change in 24-hour API from baseline to the average score of the entire period between Week 2 and Week 12.Change in 24-hour API from baseline to the average score at Week 12.

The primary sponsor of the trial is Averitas Pharma, Inc., Grünenthal’s U.S. subsidiary.

About post-surgical neuropathic pain
Post-surgical neuropathic pain (PSNP) is defined as chronic pain with neuropathic characteristics that develops or increases after surgery and persists beyond the normal healing process. It is thought to arise, at least in part, from nerve injury and pain sensitisation associated with surgery.7

The signs and symptoms of peri- and post-surgical pain can vary based on the person and the severity of the injury caused in surgery. Reported symptoms include pain caused by stimuli that are normally painless (allodynia), abnormally increased sensitivity to pain (hyperalgesia), tingling, numbness, phantom pain and scar pain.8,9,10 

About Qutenza®
In Europe, Qutenza® (capsaicin) is indicated for the treatment of peripheral neuropathic pain in adults, either alone or in combination with other medicinal products for the treatment of pain.5

Qutenza® (capsaicin) 8% topical system is approved in the US for the treatment of neuropathic pain associated with postherpetic neuralgia and for the treatment of neuropathic pain associated with diabetic peripheral neuropathy (DPN) of the feet in adults. Important US safety information is available at www.qutenza.com.6

Qutenza® is a topical TRPV1 agonist, designed to provide neuropathic pain relief for up to three months through defunctionalisation of nociceptors and nerve fibre regeneration.

About Grünenthal
Grünenthal is a global leader in pain management and related diseases. As a science-based, fully integrated pharmaceutical company, we have a long track record of bringing innovative treatments and state-of-the-art technologies to patients worldwide. Our purpose is to change lives for the better – and innovation is our passion. We focus all our activities and efforts on working towards our vision of a World Free of Pain.

Grünenthal is headquartered in Aachen, Germany, and has affiliates in 28 countries across Europe, Latin America, and the U.S. Our products are available in approx. 100 countries. In 2025, Grünenthal employed around 4,100 people and achieved revenues of €1.8 billion.

More information: www.grunenthal.com

Follow us on LinkedIn & Instagram

For further information, please contact:

Matt Crabb, Head of Global Communications (Interim) at Grünenthal

matt.crabb@grunenthal.com 

References

1 Gregory P & Settles K. Pract Pain Manag. 2013;13(9):1–6.
2 Wallace M et al. Efficacy of high-concentration capsaicin patch in post-surgical neuropathic pain (RISE). Presented at the International Association for the Study of Pain World Congress 2026.
3 Wallace M et al. Safety and tolerability of high-concentration capsaicin patch in post-surgical neuropathic pain (RISE). Presented at the International Association for the Study of Pain World Congress 2026.
4 Santos MP, Lemos F, Gomes J, Romao JM, Veiga D. Br J Pain 2024;18(1):42–56.
5 European Medicines Agency. Qutenza 179 mg cutaneous patch SmPC. Available at: https://www.medicines.org.uk/emc/product/573/smpc
6 US Food and Drug Administration. Qutenza® Prescribing Information. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/022395s019lbl.pdf
7 Correl D. F1000Res. 2017;6:1054.
8 Werner MU & Kongsgaard UE. Br J Anaesth. 2014;113(1):1–4.
9 Macrae WA. Br J Anaesth. 2008;101:77–86.
10 Searle RD & Simpson KH. Contin Educ Anaesth Crit Care Pain. 2010;10:12–14.

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SOURCE Grünenthal Group

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