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Newronika Announces First Participant Implanted in ADVENT Pivotal Study

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Milestone initiates Newronika’s international pivotal study comparing adaptive and conventional deep brain stimulation for Parkinson’s disease

MILAN, Sept. 30, 2026 /PRNewswire/ — Newronika S.p.A., a medical technology company developing adaptive deep brain stimulation therapies, today announced that the first participant in the pivotal ADVENT study has received the αDBS® implant. The procedure was performed on September 21st at the Hospital Fondazione IRCCS San Gerardo dei Tintori in Monza.

The milestone marks an important step in the ADVENT pivotal study, which is currently enrolling participants.

ADVENT is evaluating Newronika’s αDBS® adaptive deep brain stimulation system in people with Parkinson’s disease who have been referred for bilateral deep brain stimulation of the subthalamic nucleus.

“Completing the first implantation procedure in the ADVENT study at an Italian study site is an important milestone for Newronika and for the clinical development of adaptive deep brain stimulation,” said Lorenzo Rossi, Co-Founder and CEO of Newronika. “This study is designed to generate rigorous evidence by comparing adaptive and conventional stimulation in the same participants. We are grateful to the participant, the clinical team, and all the investigators contributing to this international study.”

“Performing the first implantation in ADVENT marks an important milestone for the study and for the neuromodulation program at Fondazione IRCCS San Gerardo dei Tintori, reflecting our multidisciplinary team’s commitment to advancing surgical care for people with Parkinson’s disease,” said Prof. Giorgio Carrabba, Principal Investigator for ADVENT at Fondazione IRCCS San Gerardo dei Tintori. “We thank the participant for their trust and the entire clinical team for their dedication as we begin this important phase of clinical research.”

About the ADVENT study

ADVENT—registered on ClinicalTrials.gov as NCT06891781—is a prospective, multicenter, randomized, double-blind crossover study comparing the safety and effectiveness of adaptive and conventional deep brain stimulation delivered by Newronika’s αDBS® system.

The study is expected to enroll 104 adults with idiopathic Parkinson’s disease who have been referred for bilateral deep brain stimulation of the subthalamic nucleus. Up to 18 specialist clinical sites across the United States and the European Union are expected to participate.

Because ADVENT uses a crossover design, each participant experiences both conventional and adaptive modes of stimulation in a randomly assigned order. Participants and the clinicians assessing their outcomes remain blinded to the active mode during the comparative study periods.

Newronika received FDA approval of an Investigational Device Exemption, allowing the company to initiate the ADVENT pivotal study in the future. The study is intended to support a future Premarket Approval application for Newronika’s DBS system in the United States.

Enrollment is currently underway at participating study sites in Italy and soon in the United States. Additional information about the study, including general eligibility criteria, is available on ClinicalTrials.gov under NCT06891781.

In the European Economic Area, the AlphaDBS® is CE-marked for conventional or adaptive deep brain stimulation as an adjunctive therapy to reduce symptoms of levodopa-responsive Parkinson’s disease that are not adequately controlled by medication.

About Parkinson’s disease and deep brain stimulation

Parkinson’s disease is a progressive neurological condition that can cause a range of symptoms, including movement-related symptoms such as slowness of movement, stiffness, and tremor.

Deep brain stimulation is an established treatment option for selected people whose symptoms are not adequately controlled by medication. Conventional DBS delivers stimulation using clinician-programmed settings that remain constant until they are adjusted. Adaptive DBS is designed to respond dynamically to recorded brain activity and adjust the stimulation within parameters established by the treating clinical team.

About Newronika

Newronika S.p.A. is a Milan-based medtech company and spin-off of two of Italy’s leading research institutions — Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico and the University of Milan. Built on more than 20 years of advanced research and development, Newronika develops αDBS® technology that continuously senses, analyzes, adapts to, and learns from brain signals.

Parkinson’s disease is where we start. The brain is where we’re going.

For more information, visit www.newronika.com

In the United States, the device is investigational and limited by federal law to investigational use only. It has not been cleared or approved by the U.S. Food and Drug Administration. αDBS® is a registered trademark of Newronika S.p.A.

Media contact

Communications & Investor Relations
Newronika S.p.A.
Tel: +39 02 84109381
Email: info@newronika.com
Web: www.newronika.com

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Arrowfly Launches AI for Engineers, the Definitive News Desk, Conference, Research, and Advisory Board for Engineers Navigating AI

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New year-round initiative unites a dedicated news desk, a flagship conference, original research, and an advisory board, grounded in the engineering community’s most trusted editorial brands

CLEVELAND, Sept. 30, 2026 /PRNewswire/ — Arrowfly, an award-winning B2B media and marketing company, today announced the launch of AI for Engineers, a year-round resource for engineers and technical leaders applying artificial intelligence in their work. Anchored by Arrowfly’s network of 20+ flagship engineering brands, collectively reaching 2.1 million verified industry readers, 29 million website visitors, 1.6 million email subscribers, and generating 202 million monthly impressions, AI for Engineers brings together four interconnected pillars: a dedicated News Desk, a flagship annual conference, and an Advisory Board. Together, they form a year-round platform equipping engineers with practical knowledge, peer connections, and professional guidance as AI reshapes the engineering profession.

The demand is already there. More than 30,000 engineering and technical professionals have engaged with AI topics across Arrowfly’s engineering portfolio through webinars, newsletters, and editorial content. Engineering organizations are now investing in AI across every core function, from design and R&D to automation, manufacturing operations, cybersecurity, and workforce development. As AI adoption accelerates, the need for practical, hands-on knowledge is becoming increasingly important. AI for Engineers was built to meet that demand: a year-round destination combining rigorous editorial coverage, peer-driven applied learning, and an advisory structure accountable to practitioners.

“AI is no longer a future-state consideration for engineers. It is a present-tense operational reality across product design, manufacturing, robotics, medtech, and energy,” said Amanda Buehner, Senior Vice President, Sales & Strategy, Engineering, Arrowfly. “What we’re hearing from engineering leaders is that the challenge isn’t whether to adopt AI. It’s how to move from experimentation to practical, repeatable applications that deliver results. AI for Engineers is built around that need, bringing the industry together around trusted information, real-world implementation, and direct exchange between practitioners.”

Four Pillars, One Mission

News Desk: The AI for Engineers News Desk puts specialized editors inside each engineering discipline to report on how AI is changing the work: the tools practitioners are adopting, the workflows being rebuilt, and the decisions engineers are navigating right now. Backed by more than 20 engineering brands and 2.1 million verified readers, it is the only editorial resource built from the ground up for engineers who are already building with AI.

Live Event: AI for Engineers takes place September 20–22, 2027, at M Resort Spa Casino in Henderson, Nevada, just outside Las Vegas. The three-day conference brings together an expected 700 engineers and technical leaders to learn how AI is being designed, built, and deployed across the product and plant lifecycle. Engineers attending arrive with a shared pressure: leadership has committed to AI, budgets are moving, and the question is how to build something that works. The program spans five discipline-specific content tracks covering Engineering Design and Automation, Medical Devices and Medtech, Robotics, Energy and Electronics, and Industrial Operations and Smart Manufacturing, drawing mechanical engineers, design engineers, CAD/CAE specialists, product development managers, R&D directors, medical device engineers, regulatory affairs professionals, clinical engineers, biomedical researchers, robotics engineers, automation engineers, warehouse operations managers, systems integrators, manufacturing executives, and electrical engineers. The format combines daily keynotes, editorial sessions, pre-scheduled 1:1 meetings, and speaking slots, with Day 3 closing in peer-to-peer guided conversations structured around specific AI topics. A welcome reception on Day 1 and an offsite dinner on Day 2 round out the program. Attendees leave with practical, vendor-tested AI workflows they can apply immediately.

Registration for AI for Engineers 2027 is open now. Engineers and technical leaders can register at aiforengineers.arrowfly.com/event.

Original Research: The AI for Engineers research program launches the 2027 Outlook of AI, an original peer-to-peer study spanning five engineering disciplines: AI in Engineering Design and Simulation, AI in Medical Devices and Medtech, AI in Robotics and Automation, AI in Energy and Electronics, and AI in Industrial Operations and Smart Manufacturing. The study captures how engineering organizations are adopting AI by function, what is working, where the barriers remain, and what leaders expect by 2030. Results are compiled into a gated report published in Q4 2026 and distributed across Arrowfly’s engineering portfolio and beyond. Engineers who complete the survey and qualify receive a complimentary pass to AI for Engineers 2027.

Advisory Board: Completing the initiative is the AI for Engineers Advisory Board, a council of engineering and technical leaders shaping the standards, ethics, and best practices of AI in engineering. The Advisory Board holds the entire program accountable to the engineering professionals it serves, ensuring that editorial coverage, conference programming, and research priorities reflect real practitioner priorities, not vendor agendas.

Solution providers and technology companies can reach AI for Engineers’ audience of 2.1 million verified engineering professionals, spanning every discipline from mechanical and design to robotics, Medtech, energy, and industrial operations, at organizations including Amazon, NVIDIA, Boeing, Siemens, Medtronic, and Tesla. To learn about sponsorship and partnership opportunities, contact Arrowfly’s Engineering team.

About Arrowfly

Arrowfly is a live and digital B2B destination serving professionals across the engineering, healthcare, food, retail, and hospitality sectors. Across 40+ brands, the company delivers trusted journalism, original content, live and digital events, video, and demand generation programs to the decision-makers shaping their industries. Powered by Clara, Arrowfly’s proprietary performance platform, partners get real-time visibility into audience engagement, lead quality, and campaign ROI. The company is backed by an established reputation for editorial independence and credibility across the markets it serves. For more information, visit arrowfly.com.

Media Contact:

Annie Wissner

VP of Marketing

awissner@arrowfly.com

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White Pine Capital® Strategy Named to PSN Top Guns List in US Core & Small Cap Core Universes for Q2 2026

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BLOOMINGTON, Minn. and PURCELLVILLE, Va., Sept. 30, 2026 /PRNewswire/ — White Pine Capital® announced today it has been named to the celebrated PSN Top Guns List of best performing separate accounts, managed accounts, and managed ETF strategies for Q2 2026 in two distinct universes. 

White Pine Capital’s Small Cap strategy ranked first in the PSN US Core Universe category out of 697 products and 271 firms for the one-year, and three-year periods ended second quarter 2026 (see performance).  Tim Madey, Chief Investment Officer and lead manager on the strategy, said, “It’s gratifying to help our clients meet or exceed their investment objectives. Our investment team is humbled by this recognition.”

In addition, White Pine Capital had the top ranked returns for the one-year and three-year periods in the PSN Small Cap Core Universe ending second quarter 2026 (see performance). The PSN Small Cap Core Universe is comprised of 151 products and 123 firms. The highly anticipated PSN Top Guns list, published by YCharts, remains one of the most important references for investors and asset managers.

White Pine Capital’s Small Cap strategy has a 26-year track record and has been recognized as a PSN Top Gun award winner in seventeen quarterly periods since 2018.  The firm’s investment team includes Tim Madey, Charlie Bellows, Mike Wallace, and new team member Randy Scherago.

“On behalf of YCharts, I want to extend my congratulations to this quarter’s PSN Top Guns winners for their outstanding performance during a particularly challenging period for investment managers,” says President and CEO of YCharts, Sean Brown.  “The second quarter tested even seasoned professionals, as markets shifted from early optimism to a more challenging environment that caught many portfolios off guard. What distinguishes these winners is their disciplined approach and ability to navigate uncertainty with conviction. They positioned portfolios with precision and delivered standout results when it counted most.”

Through a combination of PSN’s proprietary performance screens, the PSN Top Guns List awards products in six proprietary categories in over 75 universes based on continued performance over time.  White Pine Capital’s Small Cap strategy earned a PSN Top Guns award, meaning our strategy had one of the top ten returns for the respective period(s) in the respective strategies.

The complete list of PSN Top Guns and an overview of the methodology can be located at https://psn.fi.informais.com/PSNTopGuns/topguns_zephyr.asp

About White Pine Capital®

With offices in Bloomington, Minnesota and Purcellville, Virginia, White Pine Capital is an independent registered investment advisor with the Securities and Exchange Commission since 2000. White Pine Capital is co-managed by the firm’s President, Michael Wallace, CFA, and Chief Investment Officer, Timothy Madey. White Pine Capital provides fee-based discretionary investment advisory services to high-net-worth, family office and institutional clients.

About PSN

For more than four decades, PSN has been a top resource for investment professionals. Over 2,800 firms, 285 universes, and more than 21,000 products comprise the PSN SMA database showing asset breakdowns, compliance, key personnel, ownership diversity, ESG, business objectives and strategy, style, fees, GIC sectors, fixed income ranges and full holdings. Unique to PSN is its robust historical database of over 40 years of data including net and gross-of-fee returns. 

About YCharts

YCharts is a top-ranked investment research and client engagement platform that enables financial advisors and asset managers to make smarter investment decisions and better communicate with clients. Trusted by over 15,000 financial professionals and recognized as the Investment Research market leader by Kitces research, YCharts delivers intuitive tools for security research, portfolio construction, AI-enabled proposals, client communication, and market monitoring. In the 2026 T3 / Inside Information Technology Survey, YCharts was named a “Software All-Star” across five categories. YCharts also earned a 2025 Wealthie Award for its AI Chat feature and has been recognized ten consecutive times on the Inc. 5000 list of America’s fastest-growing private companies. Learn more at www.ycharts.com.

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SOURCE White Pine Capital

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GigU Makes Its Driver-Profit Tools Free across the U.S. and Launches on iPhone for the First Time

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The smart co-pilot for gig drivers opens its full app to every U.S. rideshare and delivery driver through the end of 2026, as new gig driver unions press for first contract with Uber and Lyft

SAN FRANCISCO, Sept. 30, 2026 /PRNewswire-PRWeb/ — GigU, the smart co-pilot that gives gig drivers the tools and knowledge to decide which trips are worth accepting in seconds, has made its full app free to every rideshare and delivery driver in the United States through the end of 2026, and launched on iPhone for the first time, broadening access to more transparency for nearly eight million workers.

Drivers who use GigU report earnings improvements of up to 30 percent after they begin screening offers (“cherry picking”) against their own costs, according to feedback the company collects directly from its users.

The app is now available on both iOS and Android at no cost, removing the subscription that’s stood between U.S. drivers and GigU’s Cherry Picker and NetProfit tools that score every incoming trip offer against a driver’s real operating costs and show, before the driver taps accept, whether the trip is worth it.

U.S. drivers who were paying GigU app subscribers before September 1 will receive one additional year of free access for being loyal customers.

“You Don’t Have to Accept What You’re Handed”

GigU built its business on a single idea: a driver who can see what a trip actually pays makes different decisions than a driver who cannot. The company is now betting that removing the subscription price for this set of tools is the fastest way to change how American gig workers earn a living for the better.

“This is a culture shift in how drivers work with these platforms in terms of GigU providing them with transparency. Until now the platforms had all the power, controlling all aspects of a gig worker’s profits. As if they were on the battlefield with tanks, and drivers are out there with sticks and stones,” said Luiz Neves, GigU CEO and co-founder. “Everything changes once a driver learns to work with strategy and real numbers instead of accepting every offer that comes in. We are making the technology free for the rest of 2026 because we do not want cost to be the reason a driver never finds that out.”

Drivers who use GigU report earnings improvements of up to 30 percent after they begin screening offers (“cherry picking”) against their own costs, according to feedback the company collects directly from its users. GigU serves more than 185,000 subscribers globally today.

Why Now

Labor Day 2026 arrived at a turning point for American gig drivers as California became home to the world’s largest union of gig workers, thanks to historic legislation. Championed by Governor Gavin Newsom and the state’s legislature last year, it provided a pathway to unionization for roughly 800,000 rideshare workers.

However, the negotiations over California drivers’ pay and benefits will take time. GigU is a tech antidote that is available to drivers now, giving them the information to screen incoming offers against their real operating costs — a practice its users report improves their profits significantly.

In May, the App Drivers Union was certified by the Massachusetts Department of Labor Relations as the exclusive bargaining representative for roughly 70,000 rideshare drivers, the first union of its kind in the country. Under the state law that created it, if the union and the platforms have not reached agreement within 180 days of certification, either side may request a mediator. That clock runs out in November.

Nationwide, gig drivers have found their earnings and take rates have declined over the past four years since Uber switched to opaque pricing algorithms on both sides of its marketplace, per Columbia Business School.

Research published in June 2026 by Len Sherman, Executive in Residence and Adjunct Professor at Columbia Business School, examined the distribution of hundreds of thousands of Uber trip offers across seventeen U.S. cities using anonymized ride-offer data from GigU users. In Dallas and Tampa, for example, where no minimum pay standards apply, half of all trip offers paid below 90 cents per mile. In Boston, where a 2024 settlement with the Massachusetts Attorney General set an hourly pay floor, ride offers averaged more than 2.5 times higher, with very few trips falling below the median rates seen in the unregulated cities.

“Left to its own devices, Uber has been able to exploit an asymmetric information advantage over drivers in a race to the bottom in pay rates,” said Sherman. “Uber initially recruited millions of drivers on a public promise that they would keep 80% of every fare. A decade and billions of trips later, in city after city, drivers are keeping less than half. No other major marketplace platform comes close to that spread.”

The same Columbia research tracked the trip histories of three veteran Uber drivers across a decade in Texas and Florida, roughly 50,000 rides in total. Uber’s share of the fare rose from 15% to 20% in the platform’s early years to more than 50% today.

The full report is available here, and GigU’s summary of the findings for drivers is available here.

What Comes Next for Drivers

GigU is building a loyalty program that connects drivers to services they use every day, including fuel, car washes and vehicle maintenance. The company is developing new tools that will let drivers compare their own results against what other drivers are earning in the same city, at the same hours, in the same conditions, closing an information gap that has favored the platforms since the rideshare industry began.

With these new features, drivers will be more connected to each other and be able to access and share valuable information to operate even better and boost their profits.

“I’ve always considered myself a fast runner, but I can only see how fast I really am if I can see how fast other people are,” said Thiago Vieira, Head of Global Expansion, GigU. “One of the biggest problems in the gig economy is that you have no feedback on how well you are performing. That is the gap we are closing for gig drivers — to give them better information to make more informed business decisions.”

Availability:

GigU is available now on the App Store and Google Play. The app is free for U.S. gig drivers through December 31, 2026. The new iOS app works with iPhones that are running iOS 17 or higher.

About GigU:

GigU gives gig-workers the tools, community and knowledge to take control of their earnings and their safety. Built from face-to-face work with drivers in Brazil, Europe and in the United States, GigU is a smart co-pilot that shows rideshare and delivery workers what a trip actually pays after their real costs, so they can choose the work worth taking. The company serves more than 185,000 subscribers across Brazil, Portugal and the United States and has raised nearly four million dollars in seed funding.

For more information, visit https://gigu.app/us and the GigU Blog: https://gigu.app/us/blog.

U.S. Media Contact:

Chris Knight

U.S. Communications & Editorial Director for GigU

@ Divino Group / MOUSA.I., on behalf of GigU

(415) 786-9226 m (on WhatsApp)

chris@divinogroup.net

U.S. Company Contact:

Thiago Vieira

Head of Global Expansion for GigU

+55 21 99664-4020 (on WhatsApp)

thiago.vieira@gigu.app

Editorial Notes & Resources:

GigU digital press kit: https://app.air.inc/a/b98V56oYR

Columbia Business School research, June 10, 2026: Uber’s Long and Winding Road to 50% Take Rates, by Len Sherman — len-sherman.medium.com

GigU Blog: The Number You Always Felt, Now on the Record – June 9, 2026

GigU Blog: California’s Uber and Lyft Drivers Just Won a Union. The Hard Part Starts Now. – August 12, 2026

GigU Blog: California certified a gig driver union. Uber already got paid. – August 25, 2026

GigU Blog: Enshittification has a name now. Drivers have lived it for years. – September 4, 2026.

GigU Blog: A seat at the table in California and a GigU celebratory table at El Cholo. – September 23, 2026

Massachusetts App Drivers Union certification: MA Department of Labor Relations, May 22, 2026 — mass.gov

Media Contact

Chris Knight, Divino Group, 1 4157869226, chris@divinogroup.net, https://gigu.app/us

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SOURCE GigU

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