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3D Artificial Cornea from Stem Cells: Chula Researchers Advance Canine Corneal Wound Treatment

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BANGKOK, July 10, 2024 /PRNewswire/ — Chulalongkorn University’s Faculty of Veterinary Science and the Faculty of Engineering have worked together to research and develop a three-dimensional artificial cornea from stem cells that offers a way to treat deep corneal wounds in dogs. The innovation helps to solve the problem of treatment methods that rely on tissue replacement which is hard to find and very expensive.  It makes it possible for dogs to be able to see clearly and comfortably once again.  

Does your dog have any of these symptoms? The inability to fully open its eyes, squinting or blinking frequently, shedding lots of tears, sometimes the tears are thick, and the mucus appears greenish.  The sclera is unusually red and not clear like before.  The cornea becomes cloudy and there are blood vessels in it.   

If your answer is “yes” then your pet might be suffering from a corneal ulcer which, if left untreated could eventually cause blindness.   

Nowadays, the number of dogs receiving treatment for corneal ulcers has increased tremendously.  The small animal hospital at the Faculty of Veterinary Medicine, Chulalongkorn University alone is already treating dogs with corneal ulcers daily.   

“We find quite a number of lesions like this in dogs.  Corneal ulcers occur as a result of many reasons, such as dogs scratching their own eyes because they have allergies causing itching around the eyes followed by scratching until the lesions form.  Fights with other dogs, being scratched by a cat, or accidentally bumps into objects” Veterinarian Dr. Chutirat Torssahakul of the Department of Internal Medicine, Faculty of Veterinary Medicine, Chulalongkorn University addressed the problems that became the starting point for the research and innovation development.  “Three-dimensional artificial cornea from stem cells” enables your beloved pet to have perfect vision once again.  “The current treatment being used is to have grafts made from replacement tissue derived from porcine bladder or canine placentas which are rare and relatively expensive.  There is also the possibility of causing post-surgery reaction and inflammation.  Therefore, we thought that if we could produce our own innovative artificial cornea using natural materials that are easily found and reduce the chance of causing inflammation this might be a better option.”  Dr. Chutirat explained.    

Three-dimensional artificial cornea from stem cells – a brighter alternative 

As a result of the effort and intention to solve eye problems for dogs, the Faculty of Veterinary Science’s research team through the Veterinary Stem Cell and Bioengineering Innovation Center (VSCBIC) has therefore embarked on additional studies on stem cells and is working with the Biomedical Engineering Research Center of the Faculty of Engineering, Chulalongkorn University recognizing its expertise in tissue engineering to help make adhesive materials for growing stem cells. 

According to Veterinary Professor Dr. Chutirat “Artificial corneal tissue is obtained by cultivating real dog corneal stem cells on a natural material structure made from silk fibroin mixed with gelatin.  The material can be cheaply and easily found in Thailand.  It is strong and durable, clear and transparent, and adheres well to cells making them three-dimensional which is comparable to real corneal tissue.” 

This innovation can be used to treat corneal perforations in dogs as well as large corneal wounds where the tissue cannot be stitched or even deep wounds in which a large amount of corneal tissue has been lost.  In cases of dogs with mild or moderate levels of corneal ulcer problems, currently, 2 methods for treatment are still in use.   

Treatment with topical eye drops is usually used in cases that are not too severe, such as a superficial wound or a bit deeper layer. Treatment with eye drops can help prevent complications due to secondary infections.  The drops do not help, however, with healing wounds since that depends on the dog’s own body mechanisms. If the body is strong and there is normal cell growth, then most cases will recover on their own.  

Treatment with surgery is used in cases of very deep wounds, complicated wounds, reaching the last layer of the cornea, or penetrating wounds where it is still possible to stitch the corneas together normally. 

“But in cases where the wound in the cornea is so large that tissue must be used to replace the missing part, we usually use a graft which could be the dog’s own conjunctiva.  The other option is to use replacement tissue such as tissues derived from human or canine placentas.  These are costly and difficult to find so we have invented a new way to treat them and that is the three-dimensional artificial cornea made from stem cells.” 

4 outstanding features of the 3D artificial cornea innovation  

It appears very similar to the real corneal surface – Research shows that stem cells grown in the lab can create tissue cells.  The extracellular matrix is interconnected and the outline is similar to the real corneal surface.  In particular, the arrangement of stem cells in the cornea is remarkable in that it is more orderly than other positions.  This will help maintain the clarity of the cornea compared to other alternative materials currently in use that are somewhat opaque.  It derives entirely from all-natural substances- The stem cells used are those that have been harvested from the cornea of the dog being treated or collected from recently deceased corpses so there is little chance of post-transplantation inflammation or irritation.  The structure for cells to adhere to is made from silk fibroin mixed with gelatin.   As time passes, stem cells create their own network of cells that form three-dimensional pieces even though the structural materials are naturally degraded by enzymes. They can be trimmed during the transplantation process – since the parts are three-dimensional sheets they can be trimmed to fit the wound where the cornea is missing.    Wounds heal faster – stem cells are living cells and have properties that help in network formation causing cell adhesion.  They also help with strengthening and building collagen so that wound healing can occur.  This is different from using graft sheets that do not contain living cells.    

At present, the “3D artificial cornea from stem cells” innovation is still in the laboratory testing stage to study whether the 3D artificial cornea can actually be used as a cornea replacement, and to determine how it interacts with the animal’s body.  According to Veterinary Professor Dr. Chutirat in many countries research on such innovations is also currently underway at the laboratory level. 

“The research we have done has produced satisfactory results.  It is expected that this innovation will be applied to dogs in the next few years.  Moreover, we have plans to apply this knowledge to cats as well from cell collection, locating cells, separating cells, and arranging cells” Dr. Chutirat concluded.   

Those who are interested can further read the research paper on the subject at https://pubmed.ncbi.nlm.nih.gov/35120168/ 

For the full release and more images, please visit: https://www.chula.ac.th/en/highlight/170754/

About Chulalongkorn University

Chulalongkorn University has made the world’s top 50 university list for employment outcomes, which reflects both the high employment rate and workability of Chula graduates. The university is also listed as the best in Thailand for the 15th Consecutive Year (since 2009), according to the newly released QS World University Rankings 2024, putting Chula at 211th in the world, up from 244th last year.

Social Media:
Facebook: https://www.facebook.com/ChulalongkornUniversity
Youtube: https://www.youtube.com/chulauniversity
Linkedin: https://www.linkedin.com/school/15101896/

 

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SOURCE Chulalongkorn University

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Innoscience’s current products are not affected by both rulings of the Munich Regional Court

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June 19, 2026

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MUNICH, June 18, 2026 /PRNewswire/ — Innoscience today announced that the Munich Regional Court has just issued a pair of rulings, from which it could be confirmed that Innoscience’s currently marketed gallium nitride (“GaN”) power device products fall outside the scope of Infineon’s asserted German patents and may be commercialized in Germany without restriction.

These rulings are fully consistent with the final determination issued last month by the U.S. International Trade Commission (“ITC”), which found that Innoscience’s current products do not infringe Infineon’s asserted U.S. patent relating to packaging design (U.S. Patent No. 9,899,481). The Munich case concerns the German counterparts of that same patent family. In line with the ITC’s findings, the Munich Court found infringement only with respect to a limited set of legacy products—certain packaged 650–700V transistors—that had already been discontinued. Therefore, any injunction granted would not apply to Innoscience’s current product portfolio. As a result, there is no impact on Innoscience’s ongoing operations or its customers’ use of its products in Germany.

The decisions mark another significant milestone in Innoscience’s string of favorable outcomes across major jurisdictions. They follow the company’s recent success in China, where it secured an injunction and damages award against Infineon, as well as its decisive victory at the ITC in the United States last month. Together, these rulings reaffirm the legality of Innoscience’s current product portfolio and its ability to operate freely in key global markets.

While proceedings in Germany remain ongoing, including Innoscience’s invalidity challenges to the asserted German patent, the growing body of decisions across China, the United States, and Germany underscores that the global litigation campaign initiated by Infineon has not altered the competitive position of Innoscience’s core products. To the contrary, independent judicial findings across multiple jurisdictions have consistently validated the robustness of Innoscience’s technology and reinforced market confidence in the company’s product compliance and innovation capabilities.

Innoscience remains committed to advancing its technology leadership and expanding its global footprint, delivering cutting-edge GaN solutions to customers worldwide in a fair and competitive marketplace.

View original content:https://www.prnewswire.com/news-releases/innosciences-current-products-are-not-affected-by-both-rulings-of-the-munich-regional-court-302805093.html

SOURCE InnoScience

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NetZoom Announces Data Center Infrastructure Management Solution for Higher Education Institutions

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1 hour ago

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June 19, 2026

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NetZoom® is a robust DCIM for managing College and University data centers, campus infrastructure and smart classrooms

CHICAGO, June 18, 2026 /PRNewswire-PRWeb/ — NetZoom offers an intuitive Data Center Infrastructure Management (DCIM) solution designed to help colleges and universities document, visualize, and manage the infrastructure supporting campus IT services, research computing, smart classrooms, and distributed data center environments.

NetZoom helps colleges and universities establish a reliable source of truth, improve operational planning, and support critical infrastructure without adding unnecessary burden to IT and facilities teams.

Higher education institutions often manage infrastructure spread across data centers, MDF/IDF closets, labs, classrooms, and multiple campus locations while supporting digital learning, campus connectivity, research workloads, and administrative systems. These environments require accurate asset management, reliable connectivity documentation, capacity planning, and operational visibility across IT and facilities.

Common infrastructure management challenges in higher education include:

Lack of a single source of truth for asset managementDistributed assets across the entire campusLimited space, power, cooling, and budget resources as digital learning, research computing, and campus IT services continue to expandMaintaining uptime and resiliency for critical academic, research, and administrative systems

“Higher education institutions are managing increasingly complex data center environments that support students, faculty, research, and campus-wide digital services,” said Uriel Campos, General Manager at NetZoom, Inc. “To manage these environments effectively, teams need clear visibility into their assets, connectivity, capacity, power, and cooling. NetZoom helps colleges and universities establish a reliable source of truth, improve operational planning, and support critical infrastructure without adding unnecessary burden to IT and facilities teams.”

NetZoom also supports IT and facilities teams by centralizing asset, connectivity, capacity, power, cooling, and change management data in a visual DCIM platform. By bringing these functions together, institutions can improve resource planning, reduce reliance on manual tracking, identify capacity constraints, and better understand the impact of infrastructure changes.

NetZoom’s DCIM solution offers significant benefits to higher education institutions including:

Campus-wide infrastructure visibility: Helps IT and facilities teams maintain a centralized view of assets across data centers, MDF/IDF closets, labs, classrooms, and distributed campus locations.Improved planning for space, power, and cooling: Provides visibility into capacity utilization so institutions can better support growing digital learning, research computing, and administrative systems.Reduced reliance on manual tracking: Centralizes asset, connectivity, capacity, and change management data to help reduce spreadsheet dependency, duplicate records, and inconsistent documentation.Operational support for limited IT resources: Helps streamline day-to-day infrastructure management, giving campus teams better access to the information needed to plan changes, troubleshoot issues, and manage equipment lifecycles.Scalable support for evolving campus technology: Allows institutions to start with core DCIM functions and expand into areas such as monitoring, reporting, service management, integrations, and advanced capacity planning as their needs grow.

Availability

NetZoom DCIM for Higher Education is immediately available in both SaaS and On-Premises deployments. For demonstrations, POCs, pricing and deployment options, contact NetZoom at 630-281-6464, email Sales@NetZoom.com or visit NetZoom.com

About NetZoom

Founded in 1995, NetZoom, Inc. is an Illinois corporation with headquarters in the Chicago area. NetZoom offers a flexible and powerful application that integrates with on-premise, virtual and cloud resources and many third-party tools like ServiceNow® to create a complete DCIM solution for data center professionals worldwide to effectively model, manage, monitor and maximize IT and Facility infrastructure.

For more information, visit NetZoom.com

NetZoom is a registered trademark of NetZoom, Inc. All other marks and names are trademarks of their respective companies.

Media Contact

Marketing Department, NetZoom, Inc., 1 630-281-6464, Marketing@NetZoom.com, https://NetZoom.com

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SOURCE NetZoom, Inc.

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NOVVA Group acquires 120 MWp Philippines solar project, anchoring its AI-era power platform in Southeast Asia

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1 hour ago

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June 19, 2026

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HONG KONG, June 19, 2026 /PRNewswire/ — NOVVA Group (“Novva”), a global AI-enabling energy infrastructure platform, announced today that it has signed a definitive agreement to acquire 100% of San Jose Solar Power Plant (“SJSP”), a utility-scale solar PV project in Bukidnon, Mindanao, from Mabuhay Power Holdings Corporation. The acquisition marks Novva’s first investment in the Philippines and a critical milestone in its strategy to build a scalable, bankable power platform across Southeast Asia.

SJSP is a 120 MWp greenfield solar project located in Barangay San Jose, in the Municipality of Quezon, Bukidnon. Once operational, it is expected to generate over 200 GWh of clean electricity per year. Construction is scheduled to begin in Q1 2027, with commercial operation targeted for 2028.

The transaction comes amid an unprecedented surge in Asian power demand, driven by the rapid expansion of artificial intelligence, cloud computing, and digital infrastructure. With energy availability emerging as the primary constraint on sustained economic growth, resilient power infrastructure has become vital. The project also advances the Philippines’ goal of a 35% renewable energy share by 2030, channelling clean capacity into one of Southeast Asia’s fastest-growing digital economies.

Steven Liu, Founder and CEO of Novva, said: “Power availability has become one of the defining constraints on future growth. With SJSP, we are securing the strategic infrastructure needed to support the next wave of industrial and digital development. By combining disciplined execution with long-term partnerships, Novva is building a reliable clean energy foundation to power the future of Southeast Asia.”

SJSP will integrate directly into Novva’s regional platform, which combines renewable generation, flexible power solutions, energy storage, grid connectivity and infrastructure financing capabilities. Novva remains committed to scaling clean energy capacity to sustain the next generation of hyperscale data centres and digital economies.

About Novva
Novva (NOVVA Group Pte. Ltd.) is a global AI-enabling energy infrastructure platform that originates, finances, builds, and operates bankable clean energy assets across Southeast Asia and Latin America. As digital transformation drives an unprecedented increase in global electricity demand, Novva scales its clean power capabilities to build the reliable energy foundation for the AI era and beyond.
www.novvaglobal.com

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SOURCE NOVVA Group

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