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Flagship Pioneering Expands Leadership Team with Key Appointments and Promotions

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CAMBRIDGE, Mass., July 10, 2024 /PRNewswire/ — Flagship Pioneering, the bioplatform innovation company, today announced additions to its leadership team through key executive appointments and promotions. Today’s personnel announcement accompanies Flagship’s announced expansion of its capital base with a capital pool of $3.6 billion to support the origination and growth of an estimated 25 breakthrough platform companies in human health, sustainability, and AI.

Lovisa Afzelius, Ph.D., has been promoted to General Partner. Afzelius joined Flagship in 2020 after leading Pfizer’s systems immunology function, where she served as executive director of clinical programs. A computational scientist by training, Afzelius came to Flagship with twenty years of leadership experience. Afzelius’ past roles included CEO, co-founder, president, chairperson of the board, and executive director in both emerging biotech and large pharma companies.

“Lovisa has showcased her exemplary leadership, vision, and commitment to pioneering original science, as evidenced by her instrumental role in the creation and scaling-up of Alltrna, Apriori Bio, Metaphore Biotechnologies, and Prologue Medicines,” said Noubar Afeyan, Ph.D., Founder and CEO of Flagship Pioneering. “I am pleased with the promotion of Lovisa to General Partner, and look forward to her continued dedication to our mission.”

Paul Biondi has also been promoted to General Partner. Biondi joined Flagship in 2019 following nearly two decades at Bristol-Myers Squibb (BMS), where he most recently served as Senior Vice President of Strategy and Business Development. As President of Flagship’s Pioneering Medicines, Biondi has grown the initiative into a robust drug development unit with a leading team of experts who bring a broad set of capabilities to Flagship and its platforms. Under Biondi’s leadership, Pioneering Medicines has established strategic partnerships with the Cystic Fibrosis Foundation, Novo Nordisk, and Pfizer.

“In just four years since he joined Flagship, Paul has transformed then nascent Pioneering Medicines into an innovation powerhouse, where thanks to his vision and leadership, we boast an R&D unit full of experts who bring an array of drug research, design and development capabilities to our organization,” said Afeyan. “The strategic partnerships he has established signify not just a tremendous opportunity for patient impact and value creation, but represent a new, innovation supply chain model for collaborations within the broader biopharma ecosystem. Beyond this, Paul has provided instrumental leadership in various capacities across Flagship and has positively impacted our growth trajectory.”

Dina Ciarimboli has been appointed as General Counsel and Executive Partner to oversee legal, corporate, IP, compliance, and related matters for Flagship Pioneering and its ecosystem of internally-operated companies. She was most recently General Counsel at EQRx, and brings over 30 years of experience advising life sciences companies and venture capital funds on corporate strategy and operations spanning company creation, early research, clinical development, and commercial launch. Ciarimboli leads legal, corporate, IP, compliance, and related matters for Flagship Pioneering and its early stage, wholly owned companies. 

“We are pleased to have Dina Ciarimboli on board as our General Counsel,” added Afeyan. “Dina’s impressive track record includes over three decades of invaluable experience advising life sciences companies and venture capital funds, which makes her a great fit for this role. Dina’s expert guidance and counsel have quickly become an asset to Flagship and its wholly-owned companies.”

Marcello Damiani has been appointed Senior Partner with a responsibility for guiding and supporting Flagship and its ecosystem companies on digital, IT strategy and operations. Damiani joins Flagship from Moderna where he served as Chief Digital and Operational Excellence Officer, developing and leading a digitization strategy using cutting edge technologies such as robotics, automation cloud computing, and artificial intelligence/machine learning in support of Moderna’s transition from preclinical through to commercial therapeutics.

“Marcello executed a potent digitization strategy during his time at Moderna, using advanced technologies like robotics, automation, cloud computing, and artificial intelligence/machine learning, and his expertise makes him an invaluable addition to our team,” added Afeyan.

Gary Pisano, Ph.D., a long-time contributor to Flagship and for the last year an academic partner while on sabbatical from Harvard Business School, has joined Flagship full time as Executive Partner and Chief Strategist. Pisano most recently served as the Harry E. Figgie, Jr. Professor of Business Administration at the Harvard Business School, where he served as Senior Associate Dean for Promotions and Tenure and has taught MBA, executive, and doctoral courses. As Chief Strategist, Pisano is tasked with tackling the broad strategic and business model choices facing Flagship with a focus on operating effectively and efficiently at scale. Pisano will also be an important resource to Flagship companies on strategy and business model design.

“We have long valued Gary’s insight and strategy at Flagship, and we are pleased to welcome him as our Chief Strategist,” added Afeyan. “Gary’s counsel and singular understanding of the Flagship model will allow him to tackle the broad strategic and business choices facing Flagship with a focus on operating effectively and efficiently at scale. A key part of his role will be helping us leverage the company’s nearly 25 years of experience, and ensuring that Flagship operates on the leading edge of management, strategy, and leadership practice.”

Enhancing Flagship’s Leadership Team

Flagship further enhanced its leadership team with the following executive appointments and elevations:

Junaid Bajwa, M.D., will join Flagship in early September as Senior Partner and Head of United Kingdom, and Science Partner for Pioneering Intelligence. He will focus on advancing new strategic opportunities and partnerships in the region for Flagship and its companies. Bajwa will join Flagship from Microsoft Research where he has been serving as Chief Medical Scientist focusing on how trusted, reliable, and human-centered AI can transform the practice of medicine. He will bring over two decades of experience across primary care, secondary care, and public health settings, and has worked as a payer and policymaker in the UK, specializing in informatics, digital transformation, and leadership.David Khougazian was recently promoted to Executive Partner, Growth and Head of Global Engagement. David brings more than 25 years of leadership experience in the global healthcare industry including over two decades at Sanofi.Justine Levin-Allerhand, Ph.D., was recently promoted to Executive Partner, Origination and Corporate Development to maximize the effectiveness of Flagship’s origination teams, thereby fueling its ecosystem with exceptional company generation and novel, durable scientific platforms.Mark Stevenson joined Flagship as Senior Partner. In this role, he will help advance Flagship’s new Enabling Technologies Initiative (ETI) and focus on driving our external partnerships. Mark brings over 30 years in the life science industry to this role, including as Executive Vice President and Chief Operating Officer of Thermo Fisher.Flagship has also expanded its rank of origination partners through the promotions of Kyle Chiang, Molly Gibson, Scott Lipnick, Armen Mkrtchyan, and Jacob Rubens.

“Flagship is dedicated to hiring and nurturing world-class executives with a history of extraordinary performance, and with these additions to our already robust leadership team, I believe we are in the strongest place we’ve been in our nearly 25-year history,” added Afeyan. “We are pleased to congratulate our colleagues on their new and expanded leadership roles. We look forward to their collaboration as we build on our mission to invent transformative technologies and companies that improve human health and the sustainability of our planet.”

About Flagship Pioneering

Flagship Pioneering invents and builds bioplatform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $75 billion in aggregate value. To date, Flagship has deployed over $3.8 billion in capital toward the founding and growth of its pioneering companies alongside more than $27 billion of follow-on investments from other institutions. The current Flagship ecosystem comprises 40 companies, including Foghorn Therapeutics (NASDAQ: FHTX), Moderna (NASDAQ: MRNA), Sana Biotechnology (NASDAQ: SANA), Generate Biomedicines, Inari, Indigo Agriculture,  and Tessera Therapeutics.

Media Contact

press@flagshippioneering.com 

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Ascendion Expands AI Advisory Community with Four Global Business and Technology Leaders

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Former Global CTO of Banco Santander, former Group CIO of Currys, former CEO of IBPAP, and former Microsoft CVP and CTO of AI join the advisory community

Advisors will provide guidance on AAVA platform innovation, AI strategy, C-suite alignment, and enterprise adoption across Asia-Pacific, Europe, North America, and the UK

The growing community of advisors will bring practitioner perspective closer to Ascendion as enterprises move AI from experimentation to governed, production-scale outcomes

BASKING RIDGE, N.J., Oct. 27, 2026 /PRNewswire/ — Ascendion, an AI-native software engineering company, today announced the appointment of four global business and technology leaders to its AI Advisory Community: Andy Gamble, Jack Madrid, Julieta Ross, Ph.D., and Joseph Sirosh, Ph.D. 

The advisors bring perspectives rarely found in one group: executives who answered to Boards, regulators, and C-suites for what technology actually delivered; a builder of AI and data platforms at global scale; and a leader who shaped one of the world’s largest technology-services and talent ecosystems. Their experience spans banking, high-tech, media, and retail. Each will work directly with Ascendion’s regional and engineering leaders, so their counsel reaches the decisions it is meant to shape. 

“We are changing how software gets built. Enterprise leaders have moved past experiments. They want AI that delivers outcomes boards can measure and risk they can manage. Andy, Jack, Julieta, and Joseph have the experience and know where transformation succeeds. They will challenge our thinking, raise our ambition, and help us navigate a period of intense — and exciting — change,” said Karthik Krishnamurthy, CEO, Ascendion. 

Each advisor will map to a different part of the business, strengthening Ascendion’s alignment with leadership communities across the globe. 

Julieta Ross, Ph.D., former Global CTO of Banco Santander, brings two decades of leading technology inside global banks, along with public-company board experience. She will work with Ascendion’s leadership on executive relationships, go-to-market strategy, and growth, and will help the company meet the governance, regulatory, and risk expectations that banking and financial services leaders place on AI. Andy Gamble, former Group CIO of Currys plc, has spent nearly three decades as a technology buyer and transformation leader across consumer electronics, industrial, and retail businesses. He will advise Ascendion’s work across Europe and the UK, with a focus on consumer goods, manufacturing, and retail, and will share what executive teams and Boards expect from a technology partner. Joseph Sirosh, Ph.D., former Microsoft CVP and CTO of AI, has spent his career building and scaling machine learning platforms in the high-tech industry. He will advise Ascendion’s engineering leadership on the evolution of AAVA and its broader platform strategy as AAVA becomes an orchestration and harness layer for enterprise AI. Jack Madrid, former President and CEO of IBPAP, spent five years leading the industry association behind one of the world’s largest technology and business-services ecosystems, centered in the Philippines. He brings robust experience working across industries, including banking, high-tech, and media, and will advise Ascendion on Asia-Pacific markets and on how AI is reshaping global delivery, skills, and workforce models. 

Together, the advisors give Ascendion an outside perspective on the full spectrum of enterprise AI, from agentic platform strategy and product engineering to industry alignment and delivery. They will add capacity to Ascendion’s ongoing work on AI governance, helping ensure trusted impact from AI-native software engineering, and their practice-based insight will inform how Ascendion applies its Engineering to the Power of AI™ approach to commercial models, platform design, service execution, and workforce development. 

About Ascendion

Ascendion is a global AI-native software engineering company delivering trusted business outcomes – capital unlock, innovation velocity, lower risk – to 250+ enterprise clients. The company delivers business outcomes at scale by combining expert engineers, AI agents, and AAVA, Ascendion’s agentic AI platform. Together, they design, engineer, and operate production-ready software that improves everyday work and life. Learn more at www.ascendion.com.

Engineering to the Power of AI™, Engineering to Elevate Life™, and AAVA™ are trademarks or service marks of Ascendion. AAVA™ is pending registration. Unauthorized use is strictly prohibited.

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AvePoint Set to Join S&P SmallCap 600

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NEW YORK, Oct. 27, 2026 /PRNewswire/ — AvePoint Inc. (NASD: AVPT) will replace LXP Industrial Trust (NYSE: LXP) in the S&P SmallCap 600 effective prior to the opening of trading on Monday, November 2. Brookfield Asset Management Ltd. and Canada Pension Plan Investment Board are acquiring LXP Industrial Trust in a deal expected to close soon, pending final closing conditions.

Following is a summary of the changes that will take place prior to the open of trading on the effective date:

Effective Date

Index Name

Action

Company Name

Ticker

GICS Sector

Nov 2, 2026

S&P SmallCap 600

Addition

AvePoint

AVPT

Information Technology

Nov 2, 2026

S&P SmallCap 600

Deletion

LXP Industrial Trust

LXP

Real Estate

ABOUT S&P DOW JONES INDICES

S&P Dow Jones Indices is the largest global resource for essential index-based concepts, data and research, and home to iconic financial market indicators, such as the S&P 500® and the Dow Jones Industrial Average®. More assets are invested in products based on our indices than products based on indices from any other provider in the world. Since Charles Dow invented the first index in 1884, S&P DJI has been innovating and developing indices across the spectrum of asset classes helping to define the way investors measure and trade the markets.

S&P Dow Jones Indices is a division of S&P Global (NYSE: SPGI), which provides essential intelligence for individuals, companies, and governments to make decisions with confidence. For more information, visit www.spglobal.com/spdji/en/. 

FOR MORE INFORMATION:

S&P Dow Jones Indices
index_services@spglobal.com

Media Inquiries
spdji.comms@spglobal.com

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SOURCE S&P Dow Jones Indices

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Archera Surpasses $5.6 Billion in Cloud and AI Spend Under Management, Closes Series C Led by Pivot Investment Partners, and Expands Insurance-Backed Cloud Commitments

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The round will help Archera expand its guaranteed cloud commitments, bringing insurance-backed financial protection to companies navigating unpredictable AI and cloud spending. The company has delivered more than $700 million in customer savings and now manages approximately $5.6 billion in annual cloud and AI spend.

BELLEVUE, Wash., Oct. 27, 2026 /PRNewswire/ — As artificial intelligence makes cloud spending harder to predict, companies face an increasingly expensive choice: commit to long-term cloud and AI contracts to unlock significant discounts or preserve flexibility and leave savings on the table. Archera has raised a $15 million Series C to expand its Guaranteed Commitments and change that equation.

The cloud economics company today announced it closed its Series C funding round, led by Pivot Investment Partners, with participation from existing investors including HighSage Ventures. The financing brings Archera’s total funding to $38.3 million. It will support the expansion of Archera’s Guaranteed Commitments and its suite of free cloud cost tools, including its FinOps Agent and MCP.

Insurance-backed financial protection is central to Archera’s next phase of growth. Archera purchased a policy on a surplus lines basis from Crum & Forster Specialty Insurance Company to back its guarantee. This model helps businesses pursue cloud commitment savings while managing the financial risk of usage changes.

The company has delivered more than $700 million in savings to over 2,200 organizations, including PubNub, Art.com, and Astronomer. The thesis behind Archera is simple: companies shouldn’t have to predict AI’s future to commit and save money on today’s infrastructure.

Why Cloud and AI Commitments Need to Change

Cloud providers reward customers who commit to spending over one- to three-year periods with substantial discounts and access to capacity. Historically, those commitments have helped businesses reduce infrastructure costs. But AI is changing the risk and economics of that decision.

A new model launch can multiply GPU spending in months. A more efficient model, a shift in architecture, or a move to a different service can reduce it just as quickly. Long-term commitments that once looked financially sound can become expensive liabilities.

Companies are left choosing between overcommitting and risking unused spend, or undercommitting and missing out on available discounts. Many choose the latter, sacrificing potential savings to preserve flexibility.

Archera believes that the trade-off is unnecessary. Its Guaranteed Commitments provide resource-level cloud and AI discounts with terms as short as 30 days. If usage declines and a covered commitment goes unused, Archera covers the cost under the terms of its guarantee.

The result is a different way to approach cloud purchasing. Businesses can pursue deeper discounts and unlock capacity otherwise gated behind a commitment, without bearing the entire financial consequence when actual usage diverges from forecasts.

Turning Cloud Optimization Into a Financial Product

Traditional cloud cost management tools provide visibility, recommendations, automation, and forecasting, but they can’t eliminate the financial risk of unused commitments. Archera combines its free FinOps platform and Agent with a financial guarantee that addresses inaccurate forecasts.

“Every tool in this market is trying to forecast your cloud usage a little better. We think that’s the wrong bet,” said Aran Khanna, co-founder and CEO of Archera. “Nobody can forecast AI demand, not the customer, not the cloud provider. So instead of predicting it, we guarantee it, and we have purchased an insurance policy to back that guarantee. If covered usage drops, we address the unused commitment cost under the terms of our guarantee. That’s a new way to purchase cloud, not another dashboard, and it’s why we’ve been able to return $700 million to our customers.”

The approach positions cloud commitments as a financial risk decision, helping finance and engineering leaders manage budgets while adapting to changing technology.

Built for CFOs, CTOs, and the Teams Managing AI Costs

The approach addresses a growing challenge across finance and engineering: how to control infrastructure costs without constraining the business.

For CFOs: Capture commitment-level discounts while reducing exposure to eligible unused spend under the guarantee.For CTOs and engineering leaders: Preserve flexibility to adopt new AI models, change architectures, and scale workloads without letting past commitments dictate future decisions.For FinOps teams: Increase commitment coverage with a financial backstop when usage changes, without more back-and-forth with engineering teams to get perfect forecasts.For cloud partners and resellers: Give customers a differentiated way to pursue cloud savings that can be reinvested in new cloud services while managing commitment risk.

Archera’s platform connects to AWS, Microsoft Azure, or Google Cloud billing data in read-only mode and analyzes actual usage. It then recommends and automates the purchasing of both native commitments and Archera Guaranteed Commitments.

Customers can evaluate their potential savings before making any purchasing decision. Commitments remain in the customer’s own cloud account, preserving end-to-end control over cloud purchasing strategy.

Archera earns when customers save through its guaranteed commitments, aligning its commercial model with the outcomes customers seek.

Customers Are Rethinking the Commitment Model

For organizations accustomed to treating cloud commitments as a single, high-stakes decision, Archera offers a more flexible approach.

“Working with Archera meant rethinking commitments as a spectrum rather than a single, high-stakes decision,” said James Hamilton, VP of Operations and Controller at PubNub. “This was a big mind shift for us. We needed to think about how our commitments could be broken up into a spectrum of purchases versus a single one-time buy.”

That flexibility is particularly valuable as companies adopt AI workloads, where technology choices and resource requirements can shift faster than traditional budgeting cycles.

Instead of making one large bet on future usage, businesses can take a more measured approach while still securing meaningful discounts.

A Series C to Expand Insurance-Backed Cloud Purchasing

Archera has been operating profitably at scale. It raised a Series C to support larger guarantees, expand its reach, serve more customers, and upgrade the insurance policies backing its guarantee to serve larger global clients.

The company plans to use the capital in three ways:

Accelerate go-to-market efforts.Expand its global partner network across North America, Europe, the Middle East, Japan, and Latin America.Serve more teams focused on AI-driven workloads.

“Archera has built a capital-efficient and differentiated business at the intersection of cloud infrastructure and risk management,” said Dinkar Jetley, co-founder and managing partner at Pivot Investment Partners. “The team pairs a deep understanding of the cloud ecosystem with a rigorous approach to underwriting, and the result is a compelling value proposition that a fast-growing roster of customers relies on as their cloud spend scales. We are privileged to have led this Series C round and look forward to working closely with Aran and the management team in the years ahead.”

Built by People Who Understand Cloud Infrastructure

Aran and Nikhil Khanna founded Archera in 2019. Aran previously planned capacity for Azure’s core compute and database services at Microsoft and was a founding member of AWS’s deep learning team leading launches, including SageMaker, DeepLens, and the Neuron SDK, behind Amazon’s Trainium and Inferentia AI chips.

His research on deep learning model efficiency has been cited more than 1,900 times, and he serves on the FinOps Foundation governing board.

As AI transforms infrastructure economics, Archera aims to make cloud savings more accessible without forcing businesses to assume unnecessary financial risk.

To explore potential savings, request a free assessment at Archera.ai.

Free savings assessment: https://app.archera.ai/savings-estimate?utm_source=forbes&utm_medium=referral&utm_campaign=series-c-2026

Name: Sarah
Email Address: shiara@archera.ai
Phone Number: +13018255007

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SOURCE Archera

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