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Rice’s Biotech Launch Pad to lead commercialization of bioelectrical implant treatment for obesity, type 2 diabetes

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$34.9M ARPA-H project aims to disrupt therapies’ market and radically improve treatment options

HOUSTON, Oct. 2, 2024 /PRNewswire/ — Rice University is part of a multiuniversity research team that has secured an award of up to $34.9 million from the Advanced Research Projects Agency for Health (ARPA-H) to accelerate the development of a bioelectronic implant designed to improve adherence for obesity and type 2 diabetes (T2D) treatment while reducing development and manufacturing costs.

Rice University’s Biotech Launch Pad will lead the commercialization effort for “Rx On-site Generation Using Electronics” (ROGUE), a self-contained, durable implantable device that houses cells engineered to produce T2D and obesity therapies in response to patients’ physiological needs.

Carnegie Mellon University leads the team of researchers driving the accelerated development and testing of ROGUE, which functions as a “living pharmacy” designed to make biologic drugs, or biologics (a rapidly expanding group of therapies derived from living cells), accessible in the body on demand. With a target cost of goods below $1,000 for at least one year of therapy, ROGUE aims to significantly lower the costs of biologics-based treatments.

ROGUE uses closed-loop bioelectronics to support, monitor and adjust drug production and dosing as well as communicate with patients. The implant will be recharged using a wearable device weekly or even less frequently, eliminating the need for managing daily, weekly or monthly medication administering, storage and restocking. This technology is designed for rapid and cost-effective deployment via a minimally invasive procedure in an outpatient clinic.

“ROGUE’s innovative design combines efficient biological manufacturing, long-term durability and patient-friendly features that have the potential to transform the landscape of biologics delivery,” said Omid Veiseh, professor of bioengineering and faculty director of the Rice Biotech Launch Pad. “With the Rice Biotech Launch Pad leading the clinical translation and commercialization efforts, this funding will allow us to expedite the development and clinical trials of this groundbreaking technology, making it accessible to patients sooner.”

In-house entrepreneur and executive director of the Rice accelerator, Paul Wotton, will be involved in every step of the process to ensure the evolution of this technology from research to clinical translation to an independent company.

“With the Biotech Launch Pad, our goal is venture creation in parallel to the groundbreaking research at Rice and its collaborating institutions,” Wotton said.

Including backing for ROGUE, the team of researchers developing the project has received over $100 million through cooperative agreements from ARPA-H and the Defense Advanced Research Projects Agency (DARPA) for two other “living pharmacy” projects — THOR and NTRAIN.

“This level of support speaks volumes to just how transformative these innovations could be, and therefore how important it is to facilitate their translation,” Wotton said.

“I am absolutely thrilled by ARPA-H’s strong support for the Rice Biotech Launchpad’s efforts in accelerating breakthrough bioelectronic technology transition from the bench to the bedside,” said Paul Cherukuri, Rice’s vice president for innovation and chief innovation officer.

Carnegie Mellon materials science and bioengineer Tzahi Cohen-Karni said that ROGUE’s bioelectronic integration represents a revolutionary advancement in biologics production.

“Our approach enables on-demand production of therapeutics in a highly energy-efficient manner,” said Cohen-Karni, who serves as primary investigator on the ARPA-H award. “This technology not only simplifies the delivery of life-saving medications but also enhances patient comfort and adherence. ROGUE’s precision and adaptability offer a much-needed improvement in both treatment efficacy and patient experience.”

Jonathan Rivnay, a professor of biomedical engineering at Northwestern University, said that biologics, including antibodies, hormones, growth factors and cytokines, are expensive and account for a significant portion of health care expenses.

“ROGUE’s ability to produce glucagon-like peptide 1 receptor agonist (GLP-1 RA) on site will address these high costs and improve patient adherence by eliminating the need for frequent injections,” Rivnay said. “GLP-1 RAs have proven effective in enhancing insulin secretion, reducing glucose levels and promoting significant weight loss, making them a first-line therapy for diabetes and obesity.

“Our collaborative efforts are paving the way for the ROGUE platform to become a revolutionary force in the field of biologics. This technology not only addresses the limitations of current biologics but also offers a sustainable, long-term solution for managing chronic diseases.”

GLP-1 RAs are a leading class of drugs for treating patients with T2D and obesity. Unlike other T2D therapies, GLP-1 RA-based drugs are also effective against obesity. Despite their efficacy, GLP-1 RAs are expensive and often inaccessible to many patients. ROGUE’s sustainable, on-demand production system will mitigate these challenges by providing a cost-effective, widely available solution, according to the research team. The ROGUE device is expected to offer the same benefits as traditional GLP-1 RAs, including the prevention of cardiovascular and kidney disease progression in high-risk patients.

This pioneering project was rigorously assessed as a potential project for ARPA-H, a federal funding agency established in 2022 to support research that has “the potential to transform entire areas of medicine and health.” This effort is funded under ARPA-H’s REACT program and includes funding for a first-in-human clinical trial for patients facing obesity and T2D. The trial preparation is slated to begin in the fifth year of the six-year project.

Other Rice co-principal investigators include Jacob Robinson, a professor of electrical and computer engineering and bioengineering who leads integration efforts for the project in line with the focus on clinical translation and commercialization; and Oleg Igoshin, a professor of bioengineering and chemistry and associate chair of the bioengineering department who oversees pharmacokinetics and pharmacodynamics modeling. 

ROGUE is a collaboration between multiple institutions, including Rice, Carnegie Mellon, Northwestern, Boston University, Georgia Institute of Technology, University of California Berkeley, the Mayo Clinic and New York City-based Bruder Consulting and Venture Group. The consortium brings together experts in biomedical engineering, synthetic biology, materials science, electrical engineering and related fields to co-design and develop the implant technology.

Download associated media assets:
https://rice.box.com/s/qc0a3wq29oyw9wobiipwnz1rxrirlo5m

About the Rice Biotech Launch Pad 

The Rice Biotech Launch Pad is a Houston-based accelerator focused on expediting the translation of Rice University’s health and medical technology discoveries into cures. This initiative is designed to help advance internally discovered platform technologies from concept to clinical studies and commercialization. The Rice Biotech Launch Pad will identify and support highly differentiated projects while driving the expansion of Houston as a world-class medical innovation ecosystem. The accelerator will bring together local researchers with a network of industry executives. For more information, please visit https://biotechlaunchpad.rice.edu/. 

About Rice University

Located on a 300-acre forested campus in Houston, Rice University is consistently ranked among the nation’s top 20 universities by U.S. News & World Report. Rice has highly respected schools of architecture, business, continuing studies, engineering, humanities, music, natural sciences and social sciences and is home to the Baker Institute for Public Policy. With 4,574 undergraduates and 3,982 graduate students, Rice’s undergraduate student-to-faculty ratio is just under 6-to-1. Its residential college system builds close-knit communities and lifelong friendships, just one reason why Rice is ranked No. 1 for lots of race/class interaction, No. 2 for best-run colleges and No. 12 for quality of life by the Princeton Review. Rice is also rated as a best value among private universities by Kiplinger’s Personal Finance.

Media Contacts: 

Chris Stipes
713-348-6778
cs216@rice.edu

Silvia Cernea Clark
713-348-6728
silviacc@rice.edu

 

View original content:https://www.prnewswire.com/news-releases/rices-biotech-launch-pad-to-lead-commercialization-of-bioelectrical-implant-treatment-for-obesity-type-2-diabetes-302260599.html

SOURCE Rice University

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LendingTree, Inc. to Report Third Quarter 2026 Earnings on November 3, 2026

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55 minutes ago

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October 20, 2026

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CHARLOTTE, N.C., Oct. 20, 2026 /PRNewswire/ — LendingTree, Inc. (NASDAQ: TREE), operator of LendingTree.com, the nation’s leading online financial services marketplace, today announced that it will release fiscal third quarter 2026 results after market close on Tuesday, November 3, 2026.  The company will also post a letter to shareholders on the Company’s website at investors.lendingtree.com.

The Company will hold its earnings conference call at 4:30 p.m. ET to discuss the release, which will be simultaneously webcast via the Company’s website at investors.lendingtree.com.  The webcast replay will be available following the event.

About LendingTree, Inc.

LendingTree, Inc. is the parent of LendingTree, LLC and several companies owned by LendingTree, LLC (collectively, “LendingTree”).

LendingTree (NASDAQ: TREE) is one of the nation’s largest, most experienced online financial platforms, created to give consumers the power to win financially.  LendingTree provides customers with access to the best offers on loans, credit cards, insurance and more through its network of over 770 financial partners.  Since its founding, LendingTree has helped millions of customers obtain financing, save money, and improve their financial and credit health in their personal journeys. With a portfolio of innovative products and tools and personalized financial recommendations, LendingTree helps customers achieve everyday financial wins.

LendingTree, Inc. is headquartered in Charlotte, NC. For more information, please visit www.lendingtree.com.

INVESTOR RELATIONS:
investors@lendingtree.com

MEDIA RELATIONS:
press@lendingtree.com

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SOURCE LendingTree, Inc.

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Hagerty to Report Third Quarter 2026 Results and Host Conference Call on Tuesday, November 3, 2026

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55 minutes ago

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October 20, 2026

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TRAVERSE CITY, Mich., Oct. 20, 2026 /PRNewswire/ — Hagerty, Inc. (NYSE: HGTY), a business that makes it easier and more enjoyable to be a driving enthusiast, today announced it will report its third quarter 2026 financial results before the market opens on Tuesday, November 3, 2026.

Hagerty will hold a conference call to discuss the financial results at 10:00 am Eastern Time on that day. A live webcast of the conference call will be available on Hagerty’s investor relations website at investor.hagerty.com. To dial-in for the conference call, please register using the link found here to receive your unique dial-in and PIN.

A webcast replay of the call will be available at investor.hagerty.com following the call.

About Hagerty, Inc. (NYSE: HGTY)
Hagerty is a company built by drivers for drivers, protecting 3.0 million vehicles in the United States, Canada and the UK. We make it easier and more enjoyable for enthusiasts to drive and celebrate the machines they love through innovative insurance products, live and digital auctions, engaging media and events, and the Hagerty Drivers Club, the world’s largest membership community of car lovers.

For more information, please visit www.hagerty.com or www.newsroom.hagerty.com. 

Category: Financial

Source: Hagerty

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Data Center Air Filtration Market to Reach USD 1.19 Billion by 2035 as Replacement Filters and Gas-Phase Media Drive Recurring Spend – DC Market Insights

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56 minutes ago

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October 20, 2026

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Market grows at an 8.59% CAGR from USD 520.20 million in 2025; replacement filters hold 78.3% of spending and gas-phase filtration grows fastest at 11.16% a year

LONDON, Oct. 20, 2026 /PRNewswire/ — The “Data Center Air Filtration Market – Growth, Share, Opportunities & Competitive Analysis, 2026-2035” report has been added to the DC Market Insights offering. The global Data Center Air Filtration Market was valued at USD 520.20 million in 2025, is estimated at USD 589.74 million in 2026, and is projected to reach USD 1.19 billion by 2035, growing at a CAGR of 8.59% from 2025 to 2035. DC Market Insights finds that this is primarily a recurring consumables market: replacement filters and media account for 78.3% of 2025 value, while liquid cooling slows first-fit demand by moving more AI rack heat away from the room air path.

Data Center Air Filtration Market at a Glance

Metric

Value (DC Market Insights estimate)

Market size, 2020

USD 314.90 million

Market size, 2025 (base year)

USD 520.20 million

Market size, 2026

USD 589.74 million (+13.4% year on year)

Market size, 2030

USD 843.18 million

Market size, 2035

USD 1.19 billion

CAGR 2025-2035

8.59% (low case 7.55%, high case 9.78%)

Largest filter type

Fine filters, 38.0% of 2025 value

Fastest-growing filter type

Gas-phase filtration, 11.16% CAGR

Leading region

North America, 39.0% (USD 202.87 million)

Fastest-growing region

Middle East and Africa, 12.13% CAGR

Market leader

Camfil, about 15% of 2025 value

Key Takeaways

USD 407.26 million, or 78.3% of 2025 value, is replacement spending because filters on the installed air-handled base are changed one to two times a year.The fleet-average filter bill is about USD 3,600 per MW of air-handled IT load a year in 2025.Gas-phase filtration grows 11.16% a year as operators manage corrosive gases and ASHRAE G1 limits in polluted and industrial hubs.Outside-air economizer intakes account for 27.0% of 2025 value and grow 10.10% a year as more sites use free-air cooling.Liquid cooling restrains first-fit demand: new-build first-fit filters grow 5.48% a year while replacement filters and media grow 9.33%.

Scope & Segmentation – Data Center Air Filtration Market

The report analyzes the market across the following segments:

Filter Type: Pre-Filters; Fine Filters; HEPA and EPA Filters; Gas-Phase Filtration; Housings, Frames and Pressure MonitoringApplication: CRAH/CRAC and Fan-Wall Recirculation; Outside-Air Economizer Intakes; Make-Up Air and Pressurization Units; Generator, Battery and Electrical RoomsPurchase Type: First-Fit with New Builds; Replacement Filters and MediaData Center Type: Hyperscale and AI Cloud Data Centers; Colocation Data Centers; Enterprise and Edge Data CentersGeography: North America; Europe; Asia Pacific; Latin America; Middle East and Africa, with 12 country forecasts

Report Updated: Oct. 20, 2026

Get Free Sample Report – Data Center Air Filtration Market

“Data center air filtration is increasingly an installed-base business. Liquid cooling reduces the air path in new AI halls, but hundreds of gigawatts of air-handled capacity still need recurring filter changes, and polluted or corrosive locations require more expensive fine and gas-phase media. That makes replacement contracts, pressure monitoring and chemical filtration the most defensible growth pools through 2035.”

— Amit Jain, Senior Consultant, ICT & Emerging Technologies, DC Market Insights, report author

Why This Report Matters

Air filtration sits at the intersection of equipment reliability, free-air cooling efficiency and contamination control. The report helps filter manufacturers, cooling vendors, data center operators, hyperscalers, colocation providers and investors size first-fit and replacement demand, compare filter classes and identify geographies where dust, smoke and corrosive gases raise lifecycle spending.

Key Attributes

Report attribute

Details

Historical Period

2020-2024

Base Year

2025

Forecast Period

2026-2035

Market Size 2025

USD 520.20 million

Market Size 2026

USD 589.74 million (+13.4% year on year)

Market Size 2035

USD 1.19 billion

CAGR 2025-2035

8.59% (low case 7.55%, high case 9.78%)

Leading Region

North America, 39.0% (USD 202.87 million)

Report Format

PDF + Excel

How Big Is the Data Center Air Filtration Market in 2026?

DC Market Insights values the Data Center Air Filtration Market at USD 589.74 million in 2026, 13.4% above 2025, as new capacity receives first-fit filters and the air-handled installed base continues to expand. The market remains tied more closely to replacement cycles than to new construction alone.

Year

Market size

2020

USD 314.90 million

2025

USD 520.20 million

2026

USD 589.74 million (+13.4% year on year)

2030

USD 843.18 million

2035F

USD 1.19 billion

Source: DC Market Insights, Data Center Air Filtration Market report, Oct. 20, 2026.

Why Does Replacement Spending Outgrow First-Fit Demand?

Liquid cooling removes a growing share of AI rack heat from the room air path, which limits the volume of first-fit filters required per new megawatt. Replacement demand behaves differently: existing air-cooled and hybrid halls continue to change pre-filters, fine filters and gas-phase media according to pressure drop, contamination and operating conditions. DC Market Insights therefore models replacement filters and media growing 9.33% a year, compared with 5.48% for first fit.

Which Filter Type Leads Data Center Air Filtration Spending?

Fine filters lead 2025 spending with 38.0% of market value, while gas-phase filtration grows fastest as operators manage sulfur dioxide, hydrogen sulfide and other corrosive contaminants around industrial and urban locations.

Filter type

2025 value

Share 2025

2035 value

CAGR

Pre-Filters

USD 109.24M

21.0 %

USD 213.46M

6.93 %

Fine Filters

USD 197.68M

38.0 %

USD 438.80M

8.30 %

HEPA and EPA Filters

USD 26.01M

5.0 %

USD 59.30M

8.59 %

Gas-Phase Filtration

USD 98.84M

19.0 %

USD 284.63M

11.16 %

Housings / Monitoring

USD 88.43M

17.0 %

USD 189.75M

7.93 %

DC Exclusive: The 1 MW Filter Change-Out Ledger

DC Market Insights estimates a 2025 fleet-average replacement bill of about USD 3,600 per MW of air-handled IT load a year. The model combines airflow, filter-face count, filter prices and change frequency across recirculation, outside-air intake, make-up air, gas-phase media and electrical-room applications. This ledger explains why the installed base, rather than only the annual build cohort, drives long-term revenue.

Metric

2025 estimate

Replacement filter bill per air-handled MW

USD 3,600/year

First-fit bill per new air-handled MW

USD 11,000

Replacement share of market

78.3 %

Air-handled load

113.1 GW

Which Region Leads the Data Center Air Filtration Market?

North America leads with 39.0% of 2025 value, while the Middle East and Africa grows fastest at 12.13% a year as desert dust and harsh ambient conditions shorten filter life on new Gulf campuses. The United States is the largest country market, while India grows rapidly because dust and corrosive gases increase the need for fine and chemical media.

Indicator

2025 / Base

Outlook

Leading region

North America, 39.0% (USD 202.87 million)

Largest regional spending pool through the forecast

Fastest-growing region

Middle East and Africa, 12.13% CAGR

Dust-intensive Gulf campuses accelerate replacement demand

Largest country

United States, USD 189.34M in 2025

Remains the largest national market

How Could the 2035 Forecast Change?

The 2035 outcome depends on how much AI heat remains on the air side and how quickly filter prices and specification levels rise. The base case assumes liquid-cooled megawatts still send part of their heat to room air and replacement costs continue to increase.

Scenario

Assumption

2035 value

CAGR 2025-2035

Low

Lower air-side heat share and slower replacement inflation

USD 1.08B

7.55 %

Base

15% air-side heat share in mature liquid-cooled halls

USD 1.19B

8.59 %

High

Higher air-side heat share and wider MERV 13 / gas-phase adoption

USD 1.32B

9.78 %

Competitive Landscape and Recent Developments

The top five suppliers account for about half of 2025 value. Competition centers on particulate efficiency, pressure drop, molecular contamination control, replacement logistics and the ability to serve hyperscale customers across multiple regions.

Companies profiled include:

Camfil; AAF International (Daikin Industries); Parker Hannifin (Filtration Group and Purafil); Freudenberg Filtration Technologies; MANN+HUMMEL; Donaldson Company; Ahlstrom.

In September 2025, Camfil opened a HEPA and ULPA filter line at its Manesar plant in India.In November 2025, Parker Hannifin agreed to acquire Filtration Group, including Purafil, for USD 9.25 billion in cash.In November 2025, AAF International launched its AstroSorb molecular filter line in the United States.In March 2026, Camfil acquired Bioconservación (Bion) of Spain to expand molecular contamination control.In May 2026, Donaldson completed its acquisition of Facet Filtration and Camfil broke ground on a 14,400-square-metre expansion in Malaysia.In August 2026, Parker completed the Filtration Group acquisition, expected to add about USD 1.8 billion to fiscal 2027 sales.

Frequently Asked Questions

What is the size of the Data Center Air Filtration Market?

USD 520.20 million in 2025 and USD 589.74 million in 2026, projected to reach USD 1.19 billion by 2035 at an 8.59% CAGR.

Which filter type leads the market?

Fine filters, including bag and rigid box filters, with 38.0% of 2025 value.

Which segment grows fastest?

Gas-phase chemical filtration, at 11.16% a year through 2035.

Why is replacement spending so important?

Filters on the installed air-handled base are replaced repeatedly, giving replacement filters and media 78.3% of 2025 value.

Which region leads?

North America with 39.0% of 2025 value; the Middle East and Africa grows fastest at 12.13% a year.

Who are the leading suppliers?

Camfil, AAF International, Parker Hannifin, Freudenberg Filtration Technologies and MANN+HUMMEL are among the leading suppliers.

Methodology

DC Market Insights builds the market bottom-up from air-handled installed IT load, annual new capacity, filter faces per MW, replacement frequency, public filter price anchors and application mix. The model is checked against an all-air ceiling, supplier sales and a MERV 8 replacement floor before regional and segment splits are reconciled.

Download Sample Report – Data Center Air Filtration Market

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Data Center Thermal Management MarketData Center Precision Air Conditioning MarketData Center Cooling MarketData Center Liquid Cooling MarketData Center Cooling Tower Market

DC Market Insights Data & Tools

Explore live datasets and decision tools used across DC Market Insights research:

Data Center Database 

Data Centers 

Data Centers Operators 

Global Data Center Capacity 

Deal Tracker 

Power Policy 

Data Center PUE Calculator 

Data Center Construction Pipeline 

Data Center Transaction Comps 

Data Center Site Risk 

Data Center Electricity Rates 

Data Center Footprint 

About DC Market Insights

DC Market Insights is a dedicated research and consulting firm that empowers data center leaders with actionable intelligence. We combine rigorous market research, advanced analytics and practical advisory support to help organizations make confident decisions in an increasingly complex digital infrastructure landscape. Our goal is to transform data into clarity, giving clients the ability to act decisively on strategy, investment and execution.

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