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Waters New Bioseparations Tools Accelerate and Improve Development of RNA-based Vaccines and Therapies Using LC-MS Analysis

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Waters new LC-MS grade reagents, enzymes, and software simplify large molecule RNA analysis to accelerate and improve development of mRNA vaccines, personalized cancer therapies, and innovative drugs for genetic disorders.Novel digestion enzymes deliver complete RNA sequence coveragei for more confident characterization, while new LC-MS-grade reagents increase sensitivity and improve detection accuracy of RNA components.iiNew waters_connect™ MAP Sequence software accelerates RNA oligonucleotide mapping using semi-automated workflows that reduce data processing time over manual techniques, enabling routine monitoring of key product attributes.

MILFORD, Mass., Oct. 14, 2024 /PRNewswire/ — Waters Corporation (NYSE: WAT) today introduced a comprehensive set of sample preparation enzymes, reagents, and waters_connect software that simplify sequence and modification confirmation of large molecule RNA therapeutics using liquid chromatography-mass spectrometry (LC-MS) analysis. When used together in a workflow, these bioseparations tools help accelerate and improve the development of innovative large molecule RNA-based pharmaceuticals, such as CRISPR sgRNA and mRNA therapeutics.

Large molecule RNA (ribonucleic acid) therapeutics represent some of the most exciting and potentially life-saving developments in pharmaceuticals today. They include new and more effective vaccines for diseases like COVID-19, personalized cancer treatments, as well as emerging CRISPR RNA therapies that address challenging genetic conditions, such as sickle cell anemia.

“As RNA-based therapies are prepared for widespread use, more direct composition measurements are needed to ensure stability, safety, and effectiveness for patients,” said Erin Chambers, Vice President, Consumables and Lab Automation at Waters Corporation. “The combination of Waters enzymes, reagents, and software are specially designed to simplify the confirmation of sequence and modifications of complex molecules. These analytical tools can accelerate RNA therapeutic development and lower barriers for use by LC-MS non-experts.”

“As innovators looking to help our customers advance nucleic acid-based therapies and reduce the burden of serious diseases, we are always seeking new technologies to improve characterization and accelerate development,” said Arnaud Delobel, PhD, R&D and Innovation Director at Quality Assistance S.A. and beta tester of the Waters RNA analytical tools. “Waters new enzymes efficiently digest mRNA and sgRNA with short incubation times and data processing in MAP Sequence allows the user to obtain reproducible results quickly with confidence.”

The Waters RNA analytical tools include:

Enzymes: Two novel enzymes, RapiZyme™ MC1 and RapiZyme Cusativin, are used in a simplified three-step protocol that provides complete LC-MS sequence coverage over traditional digestion methods enabling more confident characterization of RNA molecules.iiiReagents: IonHance™ HFIP, an LC-MS-grade reagent, is formulated to improve ionization and delivers increased spectral clarity and detection accuracy of RNA components.Software: New MAP Sequence application on the waters_connect software platform simplifies RNA LC-MS oligo mapping workflows to accelerate analysis and data processing time over manual techniques using spreadsheets.

Used together within a workflow, the tools generate an LC-MS fingerprint to confirm product identity, purity, and efficacy. The tools improve sequence coverage, LC-MS spectral data quality, and data interpretation. Supported by the compliance-ready waters_connect software platform, these tools help transition LC and LC-MS-based digestion analysis from discovery and development to release and at-line process analytical testing.

Waters RapiZyme RNAses and IonHance HFIP are now available. The new MAP Sequence App on waters_connect software will be available on October 18, 2024.

Additional Resources

Learn more about the Waters RNA Analytical ToolsListen to our webinar “Cracking the Code: Analyzing mRNA and sgRNA with Advanced Enzymes, Mass Spectrometry, and Informatics on Oct. 16 at 11:00am ETJoin Waters at the PharmSci 360 conference for an expert session on “Oligo Mapping of Large RNA Therapeutics by Novel Enzyme Specificities” with Dr. Bala Addepalli, Waters Director, R&D New Modalities Portfolio on Oct. 21, at 11:00am ETFollow and connect with Waters via LinkedIn, Twitter, and Facebook

About Waters Corporation (www.waters.com)

Waters Corporation (NYSE: WAT), a global leader in analytical instruments and software, has pioneered chromatography, mass spectrometry, and thermal analysis innovations serving the life, materials, food, and environmental sciences for more than 65 years. With approximately 7,500 employees worldwide, Waters operates directly in 35 countries, including 14 manufacturing facilities, and with products available in more than 100 countries.

Waters, Rapizyme, IonHance, and waters_connect are trademarks of Waters Technologies Corporation.

Contact:
Janice Foley
Senior Public Relations Manager, Corporate Communications
Waters Corporation
janice_foley@waters.com
+1.617.823.5555

i 100% RNA sequence coverage achieved for HPRT sgRNA digested with RapiZyme MC1 and RapiZyme Cusativin compared to traditional digestion methods such as RNase T1. Waters Application Note 720008539EN: “Tunable Digestions of RNA Using RapiZyme RNases to Confirm Sequence and Map Modifications” .

ii IonHance HFIP reagents are certified to contain less than 100 ppb sodium and less than 100 ppb potassium content, resulting in reduced adduct formation and improved sensitivity of RNA detection compared to commercially available HFIP. Waters Application Note 720008540EN: “Evaluating IonHance Hexafluoroisopropanol (HFIP) for Enhanced LC-MS Oligonucleotide Analysis”

iii Waters RapiZyme RNase protocol simplifies sample preparation with three steps including reagent preparation, RNA digestion, and heat inactivation without the need to add chemical denaturants and enzyme inhibitors.

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Tesla Owns Nearly 1 in 5 AI Answers About EVs. New 5W Index Ranks the Top 25 EV Brands by AI Citation Share.

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EV charging networks — Electrify America, EVgo, ChargePoint — are nearly invisible inside AI answers despite operating the infrastructure the entire category depends on.

MIAMI, July 25, 2026 /PRNewswire/ — 5W AI Communications, the AI Communications Firm, today released the 5W AI Visibility Index — EV, ranking the top 25 EV brands by modeled AI citation share across ChatGPT, Claude, Perplexity, Gemini, and Google AI Overviews. Tesla anchors the category at 18.4% — more than the next three brands combined. Rivian is second at 8.2%. Ford is third at 6.4%.

The Index is Volume 07 in 5W’s 2026 Consumer AI Visibility Index series. The full report is available at https://www.5wpr.com/research/ev-ai-visibility-index/.

More than a third of U.S. consumers now begin product research with an AI engine — not Google. For the EV category — where purchase consideration windows stretch six to twelve months and buyers cross-reference range, charging, ownership cost, and long-term reliability across dozens of sources — the answers the engines return are shaping the shortlist before a buyer walks into a dealership.

The Findings

Tesla dominates at 18.4% citation share — cited on virtually every consumer EV query across all five engines. Brand, product, and CEO overlap produce a citation profile no peer can match.Rivian (8.2%) is the dominant adventure-EV authority. The R1T and R1S anchor truck and SUV electric citation.Ford (6.4%) leads legacy automakers. The F-150 Lightning owns EV-truck queries; the Mach-E anchors EV-SUV comparisons.Lucid (4.8%) and Hyundai Ioniq (4.4%) complete the Tier 1 leaders. The Ioniq 5 and Ioniq 6 over-index against U.S. brand recognition.GM sits at #6 with 3.8% — despite scale — because Bolt, Lyriq, and Hummer EV are cited separately rather than as one GM-EV narrative. Ford consolidated its story. GM did not.Toyota (#17) and Honda (#18) are the two largest legacy automakers furthest behind in EV citation. The bZ4X, Solterra, and Prologue cite at rates far below what brand recognition would predict.EV charging networks are absent from the top 25. Electrify America, EVgo, and ChargePoint operate the infrastructure the entire category depends on — and have not built consumer-facing brand citation to match. The category is open.

“Every EV buyer starts inside a chatbox now. Tesla owns nearly one in five answers. The next three brands combined don’t match it. That’s a citation moat measured in AI — not TV budgets, not showroom count,” said Ronn Torossian, Founder and Chairman, 5W AI Communications. “GM is bigger than Rivian by every commercial metric and half its size in the answer. That gap costs sales. The charging networks are the biggest miss in the category — whoever builds the dominant ‘where should I charge’ answer anchors a multi-decade growth curve. Right now, none of them own it.”

The Five Engines Do Not Return Identical Answers

ChatGPT: Tesla, Rivian, Lucid, Ford, Hyundai dominate. Conservative and brand-anchored.Claude: Recurrent and CleanTechnica over-index. Data-source preference. Lighter on enthusiast brands.Perplexity: Reddit EV subreddits dominant. Out of Spec YouTube data heavily cited. Freshness-favored.Google AI Overviews: Tesla, InsideEVs, Edmunds, Kelley Blue Book dominate. Closest to a SERP-mirror.Gemini: YouTube EV creators dominate — Out of Spec, Munro Live, MKBHD at the highest rates.

Engine-aware strategy matters. A brand absent from one engine but present in another needs a different program than a brand absent across the board.

Methodology
Modeled directional estimates derived from publicly available data, observed retrieval patterns, structural signals, and the corresponding Everything-PR Citation Share Study — EV (Issue No. 07). Twenty-five brands, five engines, sixty-plus consumer-prompt query patterns. Not the output of logged query runs across millions of prompts. Intended as a strategic framework — not a definitive search-engine measurement.

The dominant outlets shaping EV citation are InsideEVs, Electrek, Recurrent, Edmunds EV, Car and Driver EV, CleanTechnica, and the Reddit-and-YouTube creator layer. Brand citation share is built primarily through presence inside that specific outlet set — and through Recurrent battery-data partnership for used-EV citation.

About 5W AI Communications
5W is the AI Communications Firm, building brand authority across the platforms where decisions now happen — ChatGPT, Claude, Perplexity, Gemini, and Google AI Overviews — alongside earned media, digital, and influencer channels. 5W combines public relations, digital marketing, Generative Engine Optimization (GEO), and proprietary AI visibility research to help clients measure and grow their presence in AI-driven buyer research. Founded in 2003, 5W is recognized as a Top U.S. PR Agency by O’Dwyer’s, named Agency of the Year in the American Business Awards®, honored as a 2026 Top Place to Work in Communications by Ragan, and named to Digiday’s WorkLife Employer of the Year list. 5W serves clients across B2C sectors — Beauty & Fashion, Consumer Brands, Entertainment, Food & Beverage, Health & Wellness, Travel & Hospitality, Technology, and Nonprofit — and B2B specialties including Corporate Communications, Reputation Management, Public Affairs, Crisis Communications, and Digital Marketing across Social, Influencer, Paid Media, GEO, and SEO. Learn more at 5wpr.com.

Media Contact
press@5wpr.com

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SOURCE 5W Public Relations

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TECNO Unveiled as Title Sponsor of The SAFF Championship Bangladesh 2026, Bringing AI Innovation to South Asian Football

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As Official Title Sponsor, TECNO joins hands with SAFF to inspire the next generation through football, innovation, and meaningful fan experiences.

DHAKA, Bangladesh, July 25, 2026 /PRNewswire/ — TECNO, an AI-driven innovative technology brand, officially announced its title sponsorship of the SAFF Championship Bangladesh 2026, South Asia’s premier international football tournament, during the tournament’s official launch ceremony in Dhaka.

Scheduled to take place from 4–17 November 2026, the championship will bring together South Asia’s leading national teams, celebrating the region’s passion for football while strengthening friendship, sporting excellence, and regional unity.

The partnership marks another milestone in TECNO’s global football journey while reinforcing the brand’s long-term commitment to South Asia—one of its most important strategic markets. Guided by its brand spirit, “Stop At Nothing,” TECNO believes football embodies the same values that define the brand: ambition, resilience, innovation, and the courage to pursue every dream.

A New Chapter for South Asian Football

The title sponsorship was officially announced during the SAFF Championship Bangladesh 2026 Official Launch Press Conference held in Dhaka. The event brought together representatives from the South Asian Football Federation (SAFF), the Bangladesh Football Federation (BFF), TECNO’s global and Bangladesh leadership teams, SAFF Member Associations, national team representatives, members of the diplomatic community, media, and digital creators to celebrate the official launch of the championship and TECNO’s role as its Title Sponsor.

Mr. Purushottam Kattel, General Secretary of SAFF, said: “The SAFF Championship represents the highest stage of football in South Asia, bringing together our Member Associations through competition, friendship, and a shared passion for the game. Today, as we unveil the identity of the SAFF Championship Bangladesh 2026, we are delighted to welcome TECNO as our Title Sponsor. This partnership reflects a shared commitment to elevating football across the region, and together we look forward to delivering a championship that inspires millions of supporters and creates lasting memories for South Asian football.”

Following the official logo unveiling ceremony, SAFF and TECNO exchanged the Title Sponsorship Agreement, formally launching their collaboration for the SAFF Championship Bangladesh 2026 and reaffirming their shared commitment to delivering an outstanding football experience for fans across South Asia.

A Shared Vision for Football

Delivering a recorded message during the ceremony, Guo Lei, General Manager of TECNO, reaffirmed the brand’s belief that football is a powerful platform for inspiring young people, connecting communities, and bringing innovation closer to fans.

“South Asia is home to one of the world’s youngest and most passionate football communities. Football has the unique power to bring people together beyond borders and cultures. We are proud to continue TECNO’s football journey through the SAFF Championship Bangladesh 2026 and look forward to working with SAFF to create unforgettable experiences for millions of football fans across the region.”

Speaking on behalf of TECNO Bangladesh, Rezwanul Hoque, CEO of Ismartu Technology BD Limited, said: “Football has become an important part of TECNO’s global journey because it reflects the values we believe in: passion, resilience, and the courage to dream bigger. Following our partnership with the Bangladesh Football Federation during the AFC Asian Cup Qualifiers, we are honoured to continue that journey as the Title Sponsor of the SAFF Championship Bangladesh 2026. Guided by our brand spirit, ‘Stop At Nothing,’ we look forward to working with SAFF and BFF to create a championship that inspires players, unites communities, and leaves a lasting legacy for football across South Asia.”

Welcoming the championship to Bangladesh, Mr. Fahad Karim, Vice President of the Bangladesh Football Federation (BFF), highlighted Bangladesh’s role as the host nation and officially marked the beginning of the journey toward the championship this November.

“Hosting the SAFF Championship 2026 is a proud moment for Bangladesh and an important milestone for football in our country. Today marks the beginning of our journey toward November, and we look forward to welcoming our fellow South Asian nations to Bangladesh for a championship that celebrates football, friendship, and regional unity. We are delighted to welcome TECNO as the Title Sponsor, and together with SAFF, our Member Associations, and our partners, we look forward to making this a memorable tournament for players, supporters, and the entire South Asian football community.”

TECNO’s Global Football Journey Continues

Football has been at the heart of TECNO’s global brand journey for nearly a decade. Through partnerships with Manchester City Football Club, the CAF Africa Cup of Nations, and the AFC Club Competitions, TECNO has consistently used football as a platform to inspire young people, connect communities, and celebrate the power of sport.

In Bangladesh, TECNO strengthened that commitment through its title sponsorship of the AFC Asian Cup Qualifiers in partnership with the Bangladesh Football Federation. The overwhelming passion shown by Bangladeshi supporters reaffirmed the country’s vibrant football culture and inspired TECNO to deepen its engagement with the sport.

The SAFF Championship Bangladesh 2026 represents the next chapter in TECNO’s football journey, reinforcing the brand’s commitment to South Asia and its rapidly growing community of young football fans.

Growing Together with Bangladesh

Bangladesh continues to be one of TECNO’s most important strategic markets. Alongside its growing smartphone business, the brand is expanding its AI ecosystem and strengthening long-term investments in retail, innovation, and local partnerships—reflecting its confidence in the country’s digital future and youthful consumer base.

Beyond technology, TECNO remains committed to empowering the next generation by supporting platforms that encourage ambition, creativity, and meaningful human connection.

Football Meets AI Innovation

Throughout the championship, TECNO plans to showcase AI-powered experiences designed to bring fans closer to the game. Powered by Ella, TECNO’s AI assistant, these experiences are intended to demonstrate how intelligent technology can enrich football engagement through interactive match information, smarter fan interactions, and immersive digital experiences.

By combining the emotional power of football with accessible AI innovation, TECNO and SAFF share a common vision of inspiring young people, strengthening communities, and creating richer experiences for football fans across South Asia.

As the countdown to November 2026 begins, TECNO, SAFF, and the Bangladesh Football Federation share a common ambition—to deliver a championship that celebrates the passion of South Asian football while inspiring the next generation through innovation, partnership, and the enduring spirit of “Stop At Nothing.”

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Tony Jaa Becomes GAC’s 30-Millionth Customer – GAC Wins Global Trust with “True Craftsmanship”

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GUANGZHOU, China, July 25, 2026 /PRNewswire/ — On July 16, at the roll-off ceremony for GAC’s 30-millionth vehicle, Feng Xingya, Chairman of GAC Group, handed over the key to the right-hand-drive GAC M8 PHEV (named GN8 overseas) to Tony Jaa. The milestone vehicle is headed straight for overseas markets.

Thai action superstar Tony Jaa’s choice reflects the trust of 30 million customers worldwide. That trust is built not on showmanship, but on GAC’s solid manufacturing “true craftsmanship.”

From Guangzhou to the world, there are no shortcuts – quality speaks for itself. While the industry runs standard “three-high” tests, GAC pushes further with “five-high, one-mountain, one-dust” extreme vehicle trials. New models undergo at least “two winters and one summer” of validation – a minimum 18 months of real-world road testing, covering 12 major categories and over 1,500 sub-items across wind tunnel labs and proving grounds.

For each overseas market, GAC conducts additional adaptive testing for local climate and road conditions – from Middle Eastern desert heat to Southeast Asia’s humidity and heavy rains.

Quality consistency starts at the smart manufacturing front. GAC’s AION Intelligent Eco-Plant is the world’s first “Lighthouse Factory” for new energy vehicles, featuring full-process digital quality monitoring. Automated robots with AI vision systems deliver millisecond response and millimeter-level precision – ensuring uniform quality whether vehicles roll off lines in Guangzhou or overseas plants.

Safety comes first. GAC’s magazine battery has been deployed in 1.5 million vehicles, accumulating over 160 billion kilometers of safe driving. The Starlink Safety Protection System serves nearly 2 million users, preventing 6.28 million potential incidents.

With this commitment to quality and safety, GAC has established a presence in 110 countries and won the trust of 30 million users. Standing at this new milestone, GAC will continue to refine its craftsmanship and deliver worry-free, high-quality mobility experiences to every customer worldwide.

For further information about GAC, please visit: https://www.gacgroup.com/en or follow us on social media.

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