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Study published in the New England Journal of Medicine AI Concludes that the Sepsis ImmunoScore™, the First FDA-Authorized AI Tool for Sepsis, has both significant Diagnostic and Predictive Power

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Groundbreaking NEJM AI Study Highlights the Ability of Prenosis’ Sepsis ImmunoScore™ to Holistically Predict Adverse Outcomes, Ushering in a New Era of Predictive Sepsis Tools Powered by AI

CHICAGO, Dec. 4, 2024 /PRNewswire/ — A new study published in the New England Journal of Medicine AI (NEJM AI) concluded the Sepsis ImmunoScore™, the first FDA-authorized AI diagnostic for sepsis, has high accuracy for the diagnosis of sepsis and for prediction of key adverse patient outcomes, concretely demonstrating the benefit of AI to inform sepsis care. Sepsis, an overactive immune response to infection, costs the U.S. healthcare system billions of dollars annually and claims the lives of at least 350,000 people each year—more than all cancers combined.

The peer-reviewed study—FDA-Authorized AI/ML Tool for Sepsis Prediction: Development and Validation—found the Sepsis ImmunoScore™ has high accuracy for sepsis diagnosis and simultaneously predicted critical outcomes, including mortality during hospitalization, length of stay before discharge, ICU admission, need for mechanical ventilation, and use of vasopressors. This represents the first time an FDA-authorized tool for sepsis can predict all of these critical outcomes simultaneously.

This milestone publication underscores the potential of Prenosis Inc.’s Sepsis ImmunoScore™ to transform sepsis management by presenting providers with trustworthy predictive information, allowing them to shift from a reactive to a proactive approach to care.

While single biomarkers, such as Procalcitonin (PCT), have been valuable tools in diagnosing sepsis for over two decades, they have limitations when trying to predict the future. The study demonstrated the combination of multidimensional inputs—vital signs, lab data, and sepsis-specific biomarkers—into a comprehensive AI-driven tool provides more reliable diagnostic information and is predictive of future patient outcomes.

“The Sepsis ImmunoScore™ is the first FDA-authorized sepsis AI algorithm that functions by embedding in the EMR and is approved to aid providers in the identification and assessment of patients with sepsis,” said Nathan I. Shapiro, MD, MPH, a Professor of Emergency Medicine at Harvard Medical School and attending physician in the Department of Emergency Medicine at Beth Israel Deaconess Medical Center, and the paper’s corresponding author1.

“For too long, clinicians have struggled with the early and accurate prediction of adverse outcomes due to sepsis, a complex, rapidly progressing condition,” said Bobby Reddy, Jr., Prenosis Co-Founder and CEO. “By delivering FDA validated AI results with transparency and explainability for clinicians, tools like the Sepsis ImmunoScore™ offer critical insights to improve patient outcomes.”

“Hospitals and clinicians now have access to the first-ever FDA-authorized, peer-reviewed AI solution that provides unmatched insights into sepsis risk and prediction of the negative outcomes associated with sepsis,” said Akhil Bhargava, the study’s lead author. “This study confirmed that AI, when validated, can be a reliable, comprehensive tool to assist providers with identification of patients at high risk of sepsis and prediction of sepsis-related adverse outcomes,” added Bhargava, Prenosis’ Senior Data Scientist — Applied Machine Learning.

About the Sepsis ImmunoScore™

FDA-authorized via the De Novo pathway in April 2024, the Sepsis ImmunoScore™ outputs a combination of both diagnostic and predictive information previously unavailable in a legally marketed device for sepsis. Unlike early warning systems that alert clinicians to potential sepsis with high amounts of false positives, leading to alert fatigue, the Sepsis ImmunoScore™ delivers actionable and trustworthy insights. The Sepsis ImmunoScore™ works in concert with a clinician’s suspicion of serious infection, providing information exactly when needed for decision-making.

The Sepsis ImmunoScore™ was built using Prenosis’ Immunix™ platform, which enables precision medicine in acute care. Immunix™ facilitates the development and validation of new precision solutions, such as AI biomarkers, and their real-time implementation. Over a decade of collaboration with more than ten U.S. partner hospitals, Prenosis used Immunix™ to build a proprietary biobank and dataset of over 113,000 blood samples from more than 28,000 patients. Prenosis merges biological data extracted from these samples with clinical information from Electronic Medical Records, creating the world’s largest biological-clinical dataset for acute care patients with suspected serious infections. This dataset enables the development of AI algorithms to detect rapid immune responses and recommend personalized therapies in real time in hospitals and emergency departments.

About Prenosis

Prenosis Inc. is an artificial intelligence company pioneering precision medicine in acute care.  We believe healthcare should be tailored to individual biology. Our data-driven approach to fast-moving biology in acute care is ushering in a new era of precision medicine. Powered by our Immunix™ precision medicine platform, we generate proprietary biological insights that drive the development of precision products and enable real-time delivery of optimal therapy. With Immunix™, we created and validated the first FDA-authorized AI biomarker for sepsis, the Sepsis ImmunoScore™.

For more information, visit: www.prenosis.com

1 Disclosure: Shapiro holds private equity in and consults for Prenosis.

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Shoplazza Launches the World’s First AI-Native Commerce Operating System with a Unified Suite of AI Agents

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April 20, 2026

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TORONTO, April 20, 2026 /PRNewswire/ — Shoplazza, a leading global commerce platform, announced the launch of the world’s first AI native commerce operating system recently, along with a unified suite of AI agents designed to execute across the entire ecommerce lifecycle. The release marks a major step forward in the company’s evolution from a traditional software platform to an AI-driven commerce infrastructure built for global scale.

At the core of the system is Shoplazza AI Store Builder, an intelligent agent that fundamentally changes how online stores are created. Instead of configuring tools manually, merchants can now generate fully functional, ready to sell storefronts through simple natural language input. By interpreting product information, target markets, and customer profiles, the system automatically builds site architecture, generates localized content, and provides initial go to market recommendations. What once required weeks of setup can now be completed in minutes, with a complete store and launch ready foundation.

Shoplazza also introduced LazzaStudio, an AI powered visual creation agent that streamlines how merchants produce content at scale. From product imagery to marketing creatives and campaign visuals, LazzaStudio transforms traditionally complex production workflows into a prompt driven process. With built in brand learning capabilities, the system generates consistent, high quality assets tailored for global audiences, enabling merchants to deploy content seamlessly across storefronts and advertising channels while significantly reducing production time and cost.

To complete the growth loop, Shoplazza launched AdValet, an AI advertising agent that automates campaign execution end to end. AdValet translates product data and market signals into audience targeting, creative generation, media planning, and campaign deployment. During live campaigns, it continuously monitors performance and dynamically optimizes outcomes through real time feedback and model iteration. This shifts advertising from manual, experience based trial and error to a system of continuous, AI-driven performance optimization.

These agents operate together within Shoplazza’s AI-native commerce operating system, where merchant intent is translated directly into coordinated execution. By unifying store creation, content production, and marketing into a single system, Shoplazza replaces fragmented workflows with an integrated layer of automation that enables faster, more predictable growth.

Shoplazza currently supports more than 650,000 merchants worldwide. With its AI-native architecture, the platform brings together previously disconnected capabilities into a single intelligent system, delivering improvements in efficiency, scalability, and operational reliability for businesses operating in increasingly complex global markets.

Looking ahead, Shoplazza will introduce Athena very soon, an AI admin agent designed to extend automation into day to day business management. Covering areas such as product management, order processing, analytics, and content operations, Athena allows merchants to interact with the system conversationally while orchestrating multiple agents in the background. This will complete a fully connected agent ecosystem spanning store creation, creative production, marketing execution, and ongoing operations.

“Commerce has reached a point where adding more tools no longer solves the problem,” said Jeff Li, Founder and CEO of Shoplazza. “What merchants need is a system that can understand intent and execute across the entire business. That is what we are building with our AI native commerce operating system. It is not just about making things easier. It is about making outcomes more predictable, scalable, and aligned with how modern commerce actually operates.”

About Shoplazza

Shoplazza is a global AI-native commerce operating system that enables brands to build, launch, and scale their online businesses. Built on an AI agent-native framework, Shoplazza integrates storefronts, marketing, payments, and operational workflows into a unified system designed to support scalable, long-term growth across global markets. Learn more at https://www.shoplazza.com/.

 

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SOURCE Shoplazza

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Pricer and JRTech Solutions sign 51 MUSD digital store transformation deal with Sobeys in Canada

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April 20, 2026

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MONTREAL, April 20, 2026 /PRNewswire/ – Pricer AB, a global leader in digital shelf-edge solutions, announces that its Canadian partner JRTech Solutions has signed a major agreement with Sobeys, one of Canada’s leading supermarket chains. The contract includes the deployment of Pricer’s latest electronic shelf label (ESL) technology and the cloud-based platform Pricer Plaza across an estimated 300–350 stores.

The agreement covers the supply of multicolor electronic shelf labels and the necessary store infrastructure, with a total hardware and infrastructure value of approximately 51 MUSD (excluding Pricer Plaza). The deployment is scheduled for an 18-month period starting in May 2026.

“We are very grateful for the trust and that Sobeys has once again chosen Pricer as its long-term strategic partner,” says Mats Arnehall, Chief Growth Officer at Pricer. “This deal confirms our leading position in the North American market and the value of our high-performance system in high-density retail environments. Our scalable cloud platform, Pricer Plaza, will be the intelligence behind every label, enabling Sobeys to act faster and work smarter.”

“After years of close collaboration and shared success, we’re proud to grow our partnership with Sobeys even further with an expanded rollout,” says Diego Mazzone, President and CEO of JRTech Solutions. “That momentum is driven by our ability to consistently deliver reliable, high-quality solutions in complex retail environments. Together, we are positioning our digital smart labels at the heart of a broader digital transformation, driving operational excellence, unlocking real-time intelligence, and creating meaningful value for both Sobeys and their customers.”

Orders will be included in Pricer’s order intake as they are received.

About JRTech Solutions
JRTech Solutions Inc. is the leading North American turnkey Electronic Shelf Label (ESL) provider and the largest worldwide distributor of Pricer ESLs, involved in over 2,000 store installations since 2008. JRTech Solutions is the exclusive Canadian provider of AI-powered inventory scanning robotics powered by Brain Corp for automated inventory management.
For further information: www.jrtechsolutions.com

About Pricer
Pricer is a pioneer and partner for in-store communication and digitalization in the rapidly evolving retail tech landscape. As a global technology leader, we empower leading retailers worldwide to shape effortless and inspiring shopping experiences that fundamentally change buying behaviors, boost sales, and drive operational efficiency. Leveraging cutting-edge innovation, we deliver scalable, high-performing solutions that easily integrate with existing systems, are energy-efficient, and user-friendly. Founded in Sweden in 1991 and listed on Nasdaq Stockholm, Pricer has delivered over 380 million electronic shelf labels in more than 28,000 stores across more than 80 countries.
For further information, please visit www.pricer.com

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SOURCE JRTECH SOLUTIONS INC.

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Mitate Zepto Technica Joins JST’s Next-generation Edge AI Semiconductor R&D Program as Social Implementation Partner

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April 20, 2026

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– MZT to Lead Product Commercialization through Its Genome-analysis Accelerator “RASEN” –

TOKYO, April 20, 2026 /PRNewswire/ — Mitate Zepto Technica, Inc. (hereinafter “MZT”), based in Tokyo’s Shibuya district, announced on April 20 that it has joined the national research initiative “Next-Generation Edge AI Semiconductor Research and Development Program” promoted by the Japan Science and Technology Agency (JST). MZT participates as a designated social implementation and commercialization partner for the research theme “Accelerating Edge Intelligence for AI for Science” (Principal Investigator: Makoto Taiji, Program Director, TRIP Headquarters, RIKEN).

Logo: https://kyodonewsprwire.jp/img/202604167540-O1-5Sz6I68Q 

This research theme aims to achieve advanced computational infrastructure through the integration of AI technology and next-generation edge semiconductors, with genome analysis as one of its key application domains. MZT participates as an organization responsible for the productization and social implementation of research outcomes through its proprietary genome-analysis accelerator “RASEN.”

Background

Since its founding in 2020, MZT has pursued a distinctive approach to genome analysis: purpose-built ASIC acceleration. Following technology validation through joint research with Tohoku University and other partners, MZT now participates as an R&D institution responsible for social implementation under this research theme.

MZT’s Role in the Program

Within this research theme, MZT will integrate AI research outcomes from RIKEN and Tohoku University into the RASEN architecture, and lead the R&D work toward social implementation through ASIC development and productization. As the industrial partner bridging research and real-world deployment, the company targets social implementation by 2029.

Program Overview

Research theme: Accelerating edge intelligence for AI for science
Promoting agency: Japan Science and Technology Agency (JST)
Principal investigator: Makoto Taiji, Program Director, TRIP Headquarters, RIKEN
Participating institutions: RIKEN, Tohoku University, Keio University, Mitate Zepto Technica
MZT’s participation start: April 2026 (FY2026)
JST program period: FY2025 onwards

Comment from Keisuke Harashima, President & CEO, Mitate Zepto Technica:
“It is a tremendous honor that we can lead the social implementation of this research theme through the acceleration of genome analysis via dedicated semiconductors — a challenge we have pursued since MZT’s founding. RASEN is at exactly the right inflection point, transitioning from research to real-world deployment. We will use this participation to accelerate commercialization across healthcare, drug discovery, and research infrastructure.”

About RASEN

RASEN is MZT’s proprietary genome-analysis accelerator under development, built on a purpose-designed ASIC architecture. In internal validation, RASEN has demonstrated the ability to complete whole-genome sequencing (WGS) analysis in approximately 5 minutes on a standard workstation — without the need for supercomputers or high-performance computing infrastructure. In independent validation studies conducted with Tohoku University, RASEN achieved 99.8% concordance with conventional analysis methods across 12 samples, confirming that its speed advantage does not come at the cost of accuracy.

About Mitate Zepto Technica

Mitate Zepto Technica is a Japanese deep-tech startup developing purpose-built semiconductor solutions for genome analysis. By harnessing cutting-edge chip technology, MZT aims to deliver transformative speed improvements in genomic computation –contributing to the resolution of global challenges in healthcare, food security, and energy through its proprietary products.

Website: https://mitatezeptotechnica.com/en/company/ 

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SOURCE Mitate Zepto Technica, Inc.

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