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UP Fintech: Record-High Quarterly and Full-Year Revenue and Profit; Q4 Net Income Up Nearly 28x YoY; Global Client Assets Reach US$41.7 Billion

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NEW YORK, March 18, 2025 /PRNewswire/ — UP Fintech Holding Limited (NASDAQ: TIGR) (“UP Fintech” or the “Company”), today announced its unaudited financial results for the fourth quarter and full year ended December 31, 2024. In the fourth quarter, the Company achieved a revenue of US$124.1 million, up 77.3% year-over-year (YoY), while full-year revenue reached US$391.5 million, a 43.7% YoY increase—both setting new record highs. Non-GAAP net income attributable to UP Fintech shareholders was US$30.5 million for the quarter, up 51.7% quarter-over-quarter (QoQ) and 2772.5% YoY, marking a record high. Full-year non-GAAP net income attributable to UP Fintech shareholders grew 65% YoY to US$70.5 million, reaching another record.

During the fourth quarter, UP Fintech added 81,300 new account openings globally, up 70.1% YoY, bringing the total number of global accounts to 2.4 million. During the quarter, the company added 59,200 new funded clients, marking a 51.4% YoY increase. For the full year 2024, UP Fintech added 187,400 new funded accounts, exceeding its annual guidance. As of the end of 2024, total funded clients reached 1,092,000, up 20.7% YoY. Supported by active market trading in the fourth quarter, total trading volume of the Company increased 142.2% YoY to US$198 billion. Net asset inflows from both individual and institutional clients reached US$1.1 billion during the quarter, while total client assets grew 36.4% YoY to a record high of US$41.7 billion.

Driving global expansion with dual focus on retail and institutional growth

Strengthening Singapore HQ, Accelerating Wealth Management for HNWIs and Family Offices

UP Fintech’s founder and CEO, Wu Tianhua, stated, “Over the past year, we achieved strong growth across all business lines, with record-high revenue and profitability in both Q4 and full-year 2024—Q4 non-GAAP net income attributable to UP Fintech shareholders was nearly 28 times higher than the prior year. Over the past three years, funded clients and total client assets have achieved CAGRs of 17.5% and 34.7% respectively, demonstrating our deepening market penetration and the continued trust and support of our global clients—key drivers of our long-term success.”

“2024 marked the Company’s 10th anniversary. With expansion into Singapore, Hong Kong, New Zealand, Australia, and the US, our global strategy drove total client assets to a record US$41.7 billion and users past 10 million. Singapore, as the Group’s headquarters, remains our largest market in terms of both new and existing clients. Hong Kong’s client assets grew by double digits as of the end of February 2025 compared to the end of 2024. Over the past year, we have rapidly expanded our business, with retail brokerage, institutional brokerage, wealth management, investment banking, and corporate services working in synergy. Beyond retail investors, we continue to earn the trust of high-net-worth and institutional clients, with retail and institutional businesses each now accounting for half of the Group’s total client assets. Looking ahead, we will continue to drive growth through our strategy of expanding markets, products, and services. We aim to meet the diverse needs of individual and institutional investors with broader offerings, fast onboarding, multi-asset trading, and tailored solutions powered by our all-in-one management platform.”

Singapore strengthens leading position with record-high annual trading volume and commission

Hong Kong full-year account openings up 48%, Obtained virtual asset exchange license

In 2024, the Company continued to broaden the reach of its globalisation strategy, increasing overall market share and enhancing brand recognition. Singapore, the Company’s headquarters, further solidified its leading position locally, delivering outstanding performance throughout the year. For the full year 2024, both total trading volume and commission income hit new records, increasing 196% and 66% YoY respectively. Net asset inflows climbed 119% YoY. The fourth quarter set new records as well, with total trading volume and commission income surging 415% and 158% YoY, respectively. Trading activity across stocks, options, and futures hit all-time highs across multiple indicators in Q4. US and Singapore stock trading volumes grew by 165% and 81% YoY, respectively, while US stock options and futures trading volumes increased by 267% and 646% YoY. Alongside these achievements, the Cash Boost trading account—designed specifically for the Singapore market to provide investors with flexible wealth management and efficient trading—doubled its account openings QoQ in the fourth quarter. Launched in partnership with a local licensed institution*, the Tiger BOSS Debit Card—Singapore’s first debit card offering fractional shares as rewards for everyday spending—saw card activations increase by over 30% QoQ during the quarter. To further expand its high-quality client base, Tiger introduced the High-Touch (Agency) Sales Module in November. Through enhanced customer onboarding, seamless trading experience and advanced risk management capabilities, the platform delivers more professional and personalized wealth management services to high-net-worth clients and institutional investors in Singapore, helping them achieve efficient asset allocation and long-term wealth growth.

The Hong Kong market continues to show strong growth momentum, with account openings rising by 48% YoY in 2024. In the fourth quarter, Hong Kong client assets increased by approximately 50% QoQ and surged sixfold YoY. Hong Kong stock trading activity increased significantly during the quarter, with trading orders and volume increasing by 62% and 90% YoY, respectively; US stock options trading volume increased by 80% QoQ. Entering 2025, driven by the recovery of the Hong Kong stock market, total client assets in Hong Kong had already achieved double-digit growth by the end of February compared to the end of 2024. Meanwhile, virtual asset trading by Hong Kong users picked up notably in Q4, with cryptocurrency trading orders doubling QoQ and trading volume increasing fourfold. Recently, the Company’s wholly-owned subsidiary, YAX (Hong Kong) Limited, received Type 1 (dealing in securities) and Type 7 (automated trading service) licenses from the Hong Kong Securities and Futures Commission (SFC). As an officially licensed virtual asset trading platform operator in Hong Kong, YAX now offers local clients with a seamless, one-stop asset management experience, providing both custody and trading services for cryptocurrencies. In addition, the Company won multiple prestigious industry accolades in Hong Kong during the fourth quarter. In particular, the Chicago Mercantile Exchange Group recognized the Company as both “Key Broker Partner 2024” and “Futures and Options Nurturer 2024”. Tiger’s industry leadership was further highlighted at the SGX-Phillip Nova Appreciation and SGX Derivatives Awards, where it was named one of the “Top 5 Chinese Futures Brokers for SGX China Index Derivatives” and one of the “Top 3 Chinese Futures Brokers for SGX Nikkei 225 Index Derivatives.”

In the US, TradeUP delivered strong performance across multiple business areas, maintaining steady growth. In the fourth quarter, supported by an exceptional trading experience, stock trading activity continued to climb, with trading volume from local clients up 38% QoQ. Options trading showed explosive growth, with trading volume and the number of contracts traded increasing by 384% and 215% respectively QoQ, highlighting TradeUP’s competitiveness and strong brand recognition in the options markets. Additionally, through its professional services and a solid market foundation, TradeUP saw a 15% QoQ growth in local customer assets, steadily expanding its market share. Moreover, TradeUP won the “Best Brokerage for Day Trading” at the Benzinga Global Fintech Awards for the second consecutive year, reaffirming its industry-leading position in efficient trading, outstanding execution, and superior user experience.

In Australia, UP Fintech achieved significant growth across key business metrics. During the fourth quarter, new account openings increased 148% YoY, while the number of first-time funded accounts rose 243.6% YoY, nearly doubling QoQ. Total first time funding amount also rose by 253.1% YoY and 151.1% QoQ – underscoring Tiger’s growing recognition and strong momentum in the Australian market. On the product side, A-Share Connect trading is now available in Australia, enabling local investors to easily access high-quality mainland Chinese stocks, further lowering the barriers for international investors to participate in the A-share market. Thanks to its outstanding trading experience and continuous innovation in financial services, the Company was also honored with the title of “Best Trading Platform Australia 2024” at the Global Banking & Finance Awards in the fourth quarter.

In New Zealand, the Company continued to expand its high-quality customer base, achieving strong growth in client assets during the fourth quarter. Total deposits increased by 272.8% YoY and 41.8% QoQ. Meanwhile, trading activity remained buoyant, with the number of trading accounts and total trading volume up by 120.2% and 111% respectively YoY. US stock trading was particularly strong, with orders for US stocks and US stock options up by 188.3% and 153.6% respectively YoY. For the full year 2024, total deposits in the New Zealand market increased 100.3% YoY, while the number of trading accounts and total trading volume grew 102.7% and 108.8% YoY, respectively.

Wealth AUC nearly doubles YoY, Institutional business widely recognized

Hong Kong IPO subscriptions up by over six times QoQ

In the fourth quarter, UP Fintech’s commission income reached US$56 million, up 35.8% QoQ and 154.9% YoY. Interest-related income amounted to US$58.5 million, an increase of 35.7% YoY. In 2024, the Company recorded US$159 million in commission income, up 71.8% YoY, while interest-related income reached US$203 million, a 25.8% YoY increase. The Company continued to enhance the one-stop global investment experience for clients. On the product side, options trading features were further upgraded, now supporting rollover of multi-leg options position, enabling investors to adjust their strategies flexibly based on market trends while improving the safety and efficiency of their capital usage. Additionally, new tools tailored for options sellers, such as Quota Calculator and Positions Calendar, were launched, along with a Top 0DTE (Zero Days to Expiration) Options leaderboard to help users quickly identify active options on trending stocks. Trading functions also saw improvements. A new “24 hour” trading option was added for US stocks, enabling investors to trade around the clock and better capture market opportunities while managing volatility. In the Wealth Section, our ETF Mall launched a new curated list of beginner-friendly US ETFs across various themes, helping users diversify their portfolios with ease.

Recently, TigerGPT, the industry’s first AI-powered investment assistant, completed a major upgrade, harnessing world-leading AI technology to deliver more accurate, in-depth market insights and support smarter, more efficient decision-making. After the upgrade, weekly user interactions increased by over 1,000%. As of February 2025, TigerGPT has served over 112,000 users globally, with more than 1.17 million conversations completed.

In the fourth quarter, the Hong Kong IPO market experienced explosive growth, with the number of subscribers increasing sixfold from the previous quarter, exceeding the total of the first three quarters of the year. The total amount of subscriptions increased by 4,123.9% QoQ, about 5.5 times the total of the first three quarters. Within the industry, we took the lead by introducing “100x leverage for all” for Hong Kong IPO subscribers. In addition, the Company promoted the “0 interest, 0 commission”** Hong Kong IPO subscription offers, truly maximising investors’ returns.

In the fourth quarter, wealth management assets under custody (AUC) from the retail side rose 98.3% YoY, with the non-money market fund assets and client numbers up 113.8% and 47.7% YoY, respectively. Among all newly funded accounts in Q4, the wealth user penetration rate reached 23%, reflecting strong client recognition of Tiger’s wealth management services. Meanwhile, we continue to enhance Tiger Wealth, upgrading the Notes section with new curated lists such as Trending Focus, Concept Portfolio, Asset Class Tracking and Conservative Focus, while expanding its offerings of complex financial products through additional structured products to meet diverse risk profiles and investment needs. Amid growing interest in Greater China investments, Tiger Wealth introduced a high-performing HKD money market fund managed by a leading Hong Kong fund house to the Singapore market, helping local investors optimize cash yields and liquidity management. In addition, we rolled out more FCN products tailored to the trading preferences of Singapore’s high-net-worth clients, further enriching their investment options.

TradingFront Turnkey Asset Management Platform (TAMP) continues to earn broad recognition from institutional clients through ongoing feature enhancements and high-quality service. The platform focuses on delivering highly customised account solutions, seamless online account opening, and multi-market, multi-asset trading support to help clients diversify their portfolios. In the fourth quarter, TradingFront’s AUC increased 33% QoQ, with the number of fixed investment accounts up 11% QoQ and structured products trading volume rising 66% QoQ. These results further reinforce TradingFront’s strong competitive position in the market.

Ranked fifth in the annual Hong Kong IPO underwriting rankings

ESOP SaaS platform achieved first full-year profitability

In the fourth quarter, our investment banking business participated in 8 US IPO projects, including Pony.ai, WeRide, and FlashEx, further demonstrating Tiger’s deep expertise and growing influence in the US IPO market. At the same time, we underwrote 9 Hong Kong IPOs, including InnoScience, MINIEYE, MGP Beauty and Dmall. With its professional underwriting services and extensive market coverage, Tiger ranked fifth in the Hong Kong stock brokerage ranking for margin financing. In 2024, the Company continued expanding its investment banking business, with the number of underwritings increasing 33% YoY. The Company ranked fifth in the Hong Kong IPO underwriting rankings, completing 32 IPOs over the year.

UP Fintech’s Employee Stock Ownership Plan (ESOP) platform, or UponeShare, added 16 new enterprise clients during the fourth quarter, bringing the total number of serviced enterprises to 613. In 2024, revenue from the ESOP SaaS platform grew 42.1% YoY, achieving annual net profit for the first time. Driven by strong client recognition and a high willingness for long-term cooperation, the Company secured 189 signed orders, with repeat orders accounting for 58.2% of the total and repeat order revenue increasing 140% YoY.

The Company added 11 new enterprise account clients during the quarter, including WeRide and COL, bringing the total number of corporate accounts to 466. During the quarter, the Company also collaborated with Li Auto to broadcast AI Talk, engaging in discussions around AI development to enhance consumer awareness of the brand. Additionally, Tiger partnered with the flagship community program “Real Trading Face to Face”, featuring an in-depth conversation between content creator “Tang Jie” and Cheetah Mobile’s CFO, exploring key highlights of Cheetah Mobile’s AI and robotics business. Furthermore, we organised investor research events for NetEase Youdao and Cheche Technology, providing insights into industry trends, technological innovations, and investment opportunities to support informed decision-making.

 *Tiger Brokers (Singapore) Pte Ltd has partnered with a local licensed partner to provide card issuance and account issuing services.

**0 commission for cash subscriptions and subscriptions with 10x leverage or below, and 0 interest on margin financing subscriptions.

About UP Fintech

UP Fintech Holding Limited (Nasdaq: TIGR), also known as Tiger Brokers, is a leading online brokerage firm with a focus on redefining global investing with technologies for the next generation.

Founded in 2014, the Company relentlessly offer superior user experience in pursuit of becoming a world-leading online brokerage, to let everyone enjoy efficient and smart investing. Currently, we offer a multitude of quality financial products and services across brokerage, employee stock ownership plan (ESOP) management, investment banking, wealth management, investor community, and investor education.
UP Fintech strives to elevate financial technology R&D to a new level. While we inherit the best traditions from the financial sector and blend them with the best minds of tech experts, we develop our own technology infrastructure—an aggregation, which enables multi-currency trading of various products across markets, guaranteeing our reliable, secure, and scalable services are accessible to all with low latency.

In March 2019, UP Fintech was listed on Nasdaq under the ticker TIGR. As of now, we serve over 10 million users and 2.4 million account holders worldwide on our flagship platform “Tiger Trade”, own 81 licenses and qualifications in different markets, and have over 1,000 employees on the team in Singapore, New Zealand, the US, Hong Kong SAR, Australia and Mainland China.

For more information about UP Fintech as a company, please visit  itiger.com

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SOURCE UP Fintech Holding Limited

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Melanie Siewert, Chief Marketing Officer at LHH, Joins the Exceptional Women Alliance (EWA)

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May 8, 2026

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LOS ANGELES, May 8, 2026 /PRNewswire/ — The Exceptional Women Alliance (EWA) proudly welcomes Melanie Siewert, Chief Marketing Officer at LHH, into its distinguished community of influential women leaders. A seasoned global marketing executive, Siewert brings more than 20 years of experience transforming brands, building high-performing teams, and driving measurable growth across both B2B and B2C industries.

As Chief Marketing Officer of LHH, Siewert leads global marketing strategy across brand, demand generation, and customer experience. She plays a critical role in aligning marketing with business objectives and fostering strong collaboration with sales to enhance organizational performance and accelerate growth. Her leadership has been instrumental in shaping a modern, customer-centric brand and building a marketing function designed to deliver consistent, high-impact results across a complex global enterprise.

Throughout her career, Siewert has held senior leadership roles at prominent organizations including Truist Financial, Worldpay, Equifax, Whirlpool Corporation, and JPMorgan Chase. She is widely recognized for guiding enterprise brand strategy, leading complex mergers, scaling marketing operations, and delivering measurable gains in pipeline, revenue, and digital adoption.

Siewert’s expertise spans marketing strategy, customer engagement, brand development, sales enablement, and cross-functional leadership. Known for her empowering leadership style and strategic vision, she consistently builds high-performing teams that drive sustainable business growth while fostering collaboration and innovation.

Her accomplishments include:

Leading global marketing strategy for LHH, integrating brand, demand generation, and customer experience to drive business performance.Guiding enterprise brand transformations and go-to-market strategies across multiple global organizations.Driving measurable growth in pipeline, revenue, and digital engagement through data-driven marketing initiatives.Leading marketing efforts through complex mergers and organizational transformations.Serving as a two-time board chair and lifetime member of Strategic & Competitive Intelligence Professionals.Recognized as a Top Woman in Marketing by PRWeek.

“Melanie’s ability to translate complex market dynamics into clear, impactful strategies, combined with her commitment to building strong, collaborative teams, makes her an exceptional addition to EWA,” said Larraine Segil. “Her leadership and results-driven approach align seamlessly with the values of our sisterhood.”

Melanie shared “I’m honored to be part of the Exceptional Women’s Alliance and look forward to learning from the incredible women leaders who are dedicated to lifting other women and impacting the world at large.”

Siewert now joins a powerful and growing community of C-suite and board-level women leaders across disciplines who share a common goal: to support one another through confidential, life-long mentoring relationships and to enrich both their professional and personal lives.

About Exceptional Women Alliance (EWA)
The Exceptional Women Alliance (EWA) is an invitation-only peer mentorship organization where high-level Exceptional Women from across multiple industries are hand-selected and invested in, to grow, learn, share, and succeed. In addition to the achievement of significant success, the criteria for acceptance include character traits that are defining of the EWA Culture – Kindness, the Spirit of Generosity, Transparency, Gratitude, and Willingness to Share their knowledge. The Foundation is a powerhouse of peer-to-peer mentoring that provides guidance, deep connection, and leadership, propelling each woman to sustainable success—one woman at a time. The life-long program enables each participant to be connected as alumnae in the ever-expanding EWA global community, as their fellow women leaders continue to move into positions of significance.

Learn more at www.exceptionalwomenalliance.com

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Insurance Modernization at Risk as Workforce Strategies Fall Behind, Says Info-Tech Research Group

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May 8, 2026

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Insurers are under pressure to modernize core systems while competing for scarce cloud, data, AI, and cybersecurity talent. Info-Tech Research Group’s new blueprint, Rebuild Your Talent Engine: Attract and Retain IT Talent in Insurance, outlines a practical framework to help insurance IT and HR leaders assess readiness, strengthen their employee value proposition, and retain the critical roles needed to accelerate transformation.

ARLINGTON, Va., May 8, 2026 /PRNewswire/ – Insurance modernization is increasingly being constrained by the people and capabilities required to deliver it, according to Info-Tech Research Group. The global research and advisory firm’s newly published blueprint, Rebuild Your Talent Engine: Attract and Retain IT Talent in Insurance, provides a structured approach to help insurers attract, retain, and mobilize the IT talent required to support digital transformation.

The firm’s research indicates that many insurers are trying to advance core system modernization while facing shortages in cloud, data, AI, and cybersecurity roles. At the same time, experienced legacy system experts are retiring, creating knowledge gaps that can slow delivery, increase operational risk, and deepen dependence on external partners.

“Insurance modernization cannot succeed if the workforce strategy behind it remains outdated,” says Vidhi Trivedi, senior research analyst at Info-Tech Research Group. “Insurers need an employee value proposition that reflects what both digital and legacy talent value today: flexibility, growth, purpose, and belonging. When organizations connect those expectations to the technology roadmap, they are better positioned to retain institutional knowledge, attract new capabilities, and move transformation forward with confidence.”

Key Workforce Risks Slowing Insurance Modernization

Info-Tech’s blueprint identifies several talent challenges that are limiting insurers’ ability to modernize effectively:

Critical digital skills remain difficult to attract and retain. Cloud engineers, data architects, cybersecurity specialists, and AI-capable technologists are essential to future-state systems, integration, and automation.Legacy expertise is leaving faster than it can be replaced. Core system knowledge remains vital to operations, compliance, and transition planning, yet many long-tenured experts are approaching retirement or feel disconnected from future-state roles.Rigid work models reduce access to high-demand talent. Digital professionals increasingly expect hybrid options, autonomy, modern delivery practices, and environments that support productivity and wellbeing.Growth pathways are not clearly connected to transformation needs. Without structured upskilling, internal mobility, and role progression, insurers risk losing employees to industries perceived as more innovative or career-accelerating.Employer branding often undersells insurance’s purpose and impact. The industry plays a critical role in protecting people, businesses, and communities, but that purpose is not always translated into a compelling technology career story.

Info-Tech’s Three-Phase Framework for Rebuilding the Insurance IT Talent Engine

To help insurers address these challenges, the Rebuild Your Talent Engine: Attract and Retain IT Talent in Insurance blueprint outlines a three-phase methodology:

Assess Talent Readiness for Modernization Success
Insurance IT and HR leaders identify modernization-critical roles, evaluate workforce pressure, assess EVP fit across key roles, and prioritize the roles that pose the greatest risk to transformation timelines.Build and Embed a Modern Employee Value Proposition
Organizations define a clear employer-employee value exchange, establish proof points across the four EVP pillars of flexibility, growth, purpose, and belonging, and activate targeted initiatives for priority roles.Develop and Present the EVP Impact Report
Leaders synthesize workforce insights, visualize progress, and present a measurable view of how EVP activation is improving retention, engagement, internal mobility, and readiness.

The resource also includes supporting tools, such as the EVP Diagnostic Tool, EVP Activation & Implementation Tool, and EVP Impact Report Template, that help insurers move from talent planning to measurable action.

“Too often, insurers view IT talent challenges as a capacity issue, when they are really a transformation risk,” explains Trivedi. ” “The insurers that move fastest will be those that know where critical capabilities are under strain, protect the expertise that increases operational resilience, and create clear pathways for employees to help shape the future of insurance from within.”

By applying Info-Tech’s framework outlined in the Rebuild Your Talent Engine: Attract and Retain IT Talent in Insurance blueprint, insurance leaders can better understand where people-related risks are highest, strengthen retention in critical roles, reduce long-term reliance on external partners, and build a more resilient technology organization. The firm’s research emphasizes that a modern EVP is not only an HR initiative but a strategic enabler of modernization success.

For exclusive and timely commentary from Info-Tech’s experts, including Vidhi Trivedi, and access to the complete Rebuild Your Talent Engine: Attract and Retain IT Talent in Insurance blueprint, please contact pr@infotech.com.

About Info-Tech Research Group

Info-Tech Research Group is the “get things done” partner for over 30,000 IT, HR, and marketing leaders worldwide. The fastest growing research and advisory firm, Info-Tech enables leaders to make well-informed decisions and transform their organizations through AI, strategic foresight, step-by-step methodologies, practical tools, industry-leading advisory, and training programs. For nearly 30 years, tens of thousands of private and public organizations have trusted Info-Tech to lead their most important initiatives through periods of change and deliver outcomes that truly matter.

To learn more about Info-Tech’s HR research and advisory services, visit McLean & Company, and for data-driven software buying insights and vendor evaluations, visit the firm’s SoftwareReviews platform.

Media professionals can register for unrestricted access to research across IT, HR, and software, and hundreds of industry analysts through the firm’s Media Insiders program. To gain access, contact pr@infotech.com.

For information about Info-Tech Research Group or to access the latest research, visit infotech.com and connect via LinkedIn and X.

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SOURCE Info-Tech Research Group

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Caris Life Sciences Submits Application to New York State Department of Health for Caris Assure Blood‑Based Testing Authorization

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May 8, 2026

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IRVING, Texas, May 8, 2026 /PRNewswire/ — Caris Life Sciences® (NASDAQ: CAI), a leading patient-centric next-generation AI TechBio company and precision medicine pioneer, today announced that it has submitted an application to the New York State Department of Health (NYSDOH) Clinical Laboratory Evaluation Program (CLEP), administered through the Wadsworth Center, seeking authorization to perform Caris Assure®, its blood‑based molecular profiling test, on specimens originating from New York State.

Caris Assure is a blood‑based molecular profiling test designed to support comprehensive biomarker analysis using a minimally invasive blood sample. Caris Assure uses circulating nucleic acids sequencing (cNAS) to analyze the whole exome (DNA) and whole transcriptome (RNA) of 22,000 genes. This comprehensive test identifies tumor alterations, clonal hematopoiesis (CH) and inherited variants, pharmacogenomic alterations, microsatellite instability (MSI) and tumor mutational burden (TMB).

The submission initiates the formal review process required by New York State for clinical laboratories seeking to perform testing on specimens collected from New York patients. Through the Wadsworth Center, CLEP conducts comprehensive reviews of laboratory permits and laboratory-developed tests to evaluate analytical validation, quality systems, personnel qualifications and compliance with applicable state regulations.

“Caris is committed to meeting the highest standards for laboratory quality, validation and regulatory compliance,” said David Spetzler, MS, PhD, MBA, President of Caris Life Sciences. “This submission of Caris Assure for review through the New York State Department of Health’s Wadsworth Center reflects our disciplined approach to expanding access to our technologies in a manner that demonstrates the rigor, responsibility and focus on the patient that define Caris Life Sciences and guide our work in the markets we serve.”

At this time, no determination has been made by NYSDOH, and Caris Assure is not authorized for use on blood-based specimens originating from New York State unless and until CLEP authorization is granted.

Caris operates a CAP-accredited, CLIA‑certified clinical laboratory and performs testing in jurisdictions where it is authorized to do so, in accordance with all applicable federal, state, and local regulations. Any future availability of Caris Assure in New York State will be contingent upon completion of the CLEP review process administered by the Wadsworth Center and receipt of the appropriate authorization.

About Caris Life Sciences
Caris Life Sciences® (Caris) is a leading, patient-centric, next-generation AI TechBio company and precision medicine pioneer actively developing and commercializing innovative solutions to transform healthcare. Through comprehensive molecular profiling (Whole Genome, Whole Exome and Whole Transcriptome Sequencing), advanced AI and machine learning, Caris has created the large-scale, multimodal clinico-genomic database and computing capability needed to analyze and further unravel the molecular complexity of disease. This convergence of next-generation sequencing, AI and machine learning technologies and high-performance computing provides a differentiated platform for developing the latest generation of advanced precision medicine diagnostic solutions for early detection, diagnosis, monitoring, therapy selection and drug development.

Caris was founded with a vision to realize the potential of precision medicine to improve the human condition. Headquartered in Irving, Texas, Caris has offices in Phoenix, New York, Cambridge (MA), Tokyo, Japan and Basel, Switzerland. Caris or its distributor partners provide services in the U.S. and other international markets.

Forward Looking Statements

This press release contains forward-looking statements, within the meaning of the Private Securities Litigation Reform Act of 1995 and other federal securities laws. All statements other than statements of historical facts contained in this press release are forward-looking statements, including statements regarding our business, solutions, plans, objectives, goals, industry trends, financial outlook and guidance. In some cases forward-looking statements can be identified by words such as “may,” “will,” “should,” “would,” “expect,” “plan,” “anticipate,” “could,” “intend,” “target,” “project,” “potential,” “contemplate,” “believe,” “estimate,” “predict,” or “continue” or similar expressions.

You should not rely upon forward-looking statements as predictions of future events. Although we believe that the expectations reflected in these forward-looking statements are reasonable based on information currently available to us, we cannot guarantee that the future results, discoveries, levels of activity, performance or events and circumstances reflected in forward-looking statements will be achieved or occur. Forward-looking statements involve known and unknown risks and uncertainties, some of which are beyond our control. Risks and uncertainties that could cause our actual results to differ materially from those indicated or implied by the forward-looking statements in this press release include, among other things: our future financial performance, results of operations or other operational results or metrics; development, analytical and clinical validation, timing and performance of future solutions by us and our competitors; commercial market acceptance for our solutions, including acceptance of preventive as well as diagnostic testing paradigms, and our ability to meet resulting demand; the rapidly evolving competitive environment in which we operate; third-party payer reimbursement and coverage decisions related to our solutions; risks related to data management, storage, and processing capabilities and our ability to integrate and deploy artificial intelligence and advanced data analytics technologies; our ability to protect and enhance our intellectual property; regulatory requirements, decisions or approvals (including the timing and conditions thereof) related to our solutions, including our application for New York State Department of Health approval for Caris Assure; reliance on third-party suppliers; risks related to data security, patient privacy, and compliance with healthcare data protection regulations as well as potential cybersecurity threats to our data platforms; our compliance with laws and regulations; the outcome of government investigations and litigation; risks related to our indebtedness; and our ability to hire and retain key personnel as well as risks, uncertainties; and other factors described in the section titled “Risk Factors” and elsewhere in our Annual Report on Form 10-K filed on March 3, 2026, and in our other filings we make with the SEC from time to time. We undertake no obligation to update any forward-looking statements to reflect changes in events, circumstances or our beliefs after the date of this press release, except as required by law.

Caris Life Sciences Media:
Corporate Communications
CorpComm@CarisLS.com
214.294.5606 

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SOURCE Caris Life Sciences

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