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HERVolution Therapeutics Demonstrates Preclinical Proof-of-Concept for Insulin Sensitization Immune Therapy in Metabolic Disease and Announces Exclusive License Agreement with the University of Copenhagen

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Preclinical studies in disease-relevant models demonstrate the ability of HERVolution’s HERV-targeting platform to control weight gain, reverse type 2 diabetes, and lower “inflammaging” biomarkers

Exclusive license agreement, combined with core company-owned IP, further solidifies the potential of IPT-001 in metabolic disease and longevity

COPENHAGEN, Denmark and NEW YORK, June 10, 2026 /PRNewswire/ — HERVolution Therapeutics ApS, a biotechnology company pioneering human endogenous retrovirus (HERV)-targeting immunotherapies for metabolic diseases, longevity, and oncology, today announced preclinical proof-of-concept for its proprietary technology in metabolic disease, presented at the American Diabetes Association 2026 Scientific Sessions, held June 5-8, 2026, in New Orleans. The company concurrently announced an exclusive license agreement with the University of Copenhagen (UCPH) covering the commercialization of HERV-targeting technology for controlling weight gain.

Studies conducted in collaboration with researchers at UCPH successfully applied HERVolution’s proprietary technology to engage endogenous retroviral targets in preclinical models of weight gain, demonstrating the ability of an immune therapy to control weight gain in a high fat diet plus underlying metabolic disease context.

In parallel, HERVolution and UCPH have entered into an exclusive license agreement as an outcome of their research collaboration. Under the agreement, HERVolution receives exclusive rights to develop, manufacture and commercialize products in the licensed field.

Together, the preclinical results and the licensing framework establish a foundation for HERVolution to advance HERV-targeting immunotherapies for metabolic diseases as a core therapeutic pillar alongside its oncology program, consistent with the Company’s broader ambition to apply its HERV-targeting platform across oncology, metabolic diseases, and ultimately longevity.

“These preclinical results are an important validation of our dark genome-derived technology beyond oncology. Demonstrating that our platform has broad utility to engage endogenous retroviral targets in metabolic disease models opens a meaningful direction for the Company,” said J. Robert Coleman, PhD, MBA, CEO of HERVolution Therapeutics. “The license agreement with the University of Copenhagen, combined with our solely owned, proprietary IP provides a strong foundational framework to advance a new class of off-the-shelf, HERV-targeting immunotherapies for some of the world’s most prevalent conditions.”

About HERVolution Therapeutics

HERVolution Therapeutics is a biotechnology company pioneering human endogenous retrovirus (HERV)-targeting immunotherapies for oncology, metabolic diseases, and longevity. HERVs are ancient viral sequences embedded in the human genome that become reactivated in cancer and other diseases of aging. By directing the immune system against HERV-derived antigens, HERVolution aims to deliver a new class of senolytic therapies across multiple indications where HERV reactivation and cellular senescence contribute to disease biology. The Company’s lead program, IPT-001, is advancing toward first-in-human studies in oncology and metabolic disease. For more information, visit hervolutiontx.com. Follow us on LinkedIn and X.

About the University of Copenhagen
Founded in 1479, the University of Copenhagen (UCPH) is one of the leading research universities in Europe, with a strong tradition in biomedical and translational research. UCPH actively supports the translation of academic discoveries of therapeutic potential into clinical development through partnerships with industry.

Media Contact

HERVolution Therapeutics ApS
HERVolution Therapeutics
communications@hervolutiontx.com
www.hervolutiontx.com

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SOURCE HERVolution Therapeutics

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LarrainVial and inCadense Join Forces to Advance Next-Generation Wealth Infrastructure Across Latin America

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Collaboration combines LarrainVial’s regional distribution leadership with inCadense’s international SMA, UMA and multi-currency managed accounts platform to support the transition toward fee-based wealth solutions

SANTIAGO, Chile, Aug. 31, 2026 /PRNewswire-PRWeb/ — inCadense Corp., a global managed accounts provider to the asset and wealth management industry, today announced a strategic collaboration with LarrainVial to expand access to international managed account capabilities across Latin America, local wealth markets and U.S. Offshore channels.

“Bringing LarrainVial’s market reach together with inCadense’s international managed account infrastructure gives us an opportunity to address those needs and bring new solutions to the region.” – Andres Bulnes, Partner and Global Head of Distribution at LarrainVial

The collaboration brings together LarrainVial’s deep market presence, distribution capabilities and extensive relationships across Latin American wealth and asset management with inCadense’s International Turnkey Asset Management Platform, iTAMP®, creating infrastructure to support the delivery of separately managed accounts (SMAs), unified managed accounts (UMAs), model portfolios and other fee-based investment solutions across currencies, custodians and jurisdictions.

Through iTAMP®, asset managers and wealth managers can use a common operating framework spanning portfolio construction, model and strategy delivery, account-level implementation, trading connectivity, multi-custody, multi-currency capabilities, rebalancing and reporting. The architecture is designed specifically for international wealth markets where investment products, currencies, custody arrangements and regulatory structures can vary significantly by client and jurisdiction.

The relationship is intended to help address an important infrastructure opportunity across Latin America: enabling wealth firms to move beyond predominantly transactional product distribution toward scalable, portfolio-based and fee-based advisory models while broadening access to global investment capabilities.

LarrainVial occupies a distinctive position in Latin American financial services, the firm has developed an integrated financial platform spanning third-party distribution, asset management, wealth management, brokerage and other financial services, with an extensive presence across Latin America and the U.S. Offshore market. LarrainVial has identified third-party distribution as a core strategic pillar and has continued to expand its multi-firm distribution model across the region and internationally.

“Latin America is moving toward a more global, advisory-led wealth management model, and that evolution requires infrastructure capable of supporting it,” said Andrés Bulnes, Partner and Global Head of Distribution at LarrainVial. “inCadense brings an international managed account architecture designed for the realities of these markets — multiple custodians, currencies, investment structures and jurisdictions. We see a significant opportunity to work together to bring new capabilities to our clients and partners across Latin America and the Offshore market.”

Bulnes continued, “Many of the next opportunities in Latin American wealth management are infrastructure challenges as much as they are investment-product challenges. Managers need a way to move strategies across borders. Wealth firms need scalable SMA and UMA capabilities. Advisors need greater flexibility across currencies, custodians and investment structures. Bringing LarrainVial’s market reach together with inCadense’s international managed account infrastructure gives us an opportunity to address those needs and bring new solutions to the region.”

The collaboration builds on LarrainVial’s strategy of connecting investment managers and financial intermediaries with differentiated investment solutions. Its recent expansion in U.S. Offshore has emphasized scale, dedicated distribution resources and a multi-manager approach designed to deepen client relationships and broaden the range of investment capabilities available across the region.

“LarrainVial is a market leader in Latin America and has built one of the region’s most impressive financial platforms, with capabilities spanning distribution, asset management and wealth management,” said A.J. Harper, Managing Partner and Co-Founder of inCadense. “What stands out is their deep commitment to bringing new investment solutions to market and their ability to reach clients across both local and offshore channels. We are extremely pleased to work with the LarrainVial team to expand the infrastructure supporting fee-based advice, managed accounts and global investment capabilities throughout the region.”

inCadense’s open-architecture model is designed to connect asset managers, wealth managers, custodians and execution providers within a unified managed account environment. The platform can support international securities and investment structures including UCITS, foreign ordinary shares, global fixed income, ETFs, mutual funds, separately managed accounts and, where appropriate, alternative and private-market investments.

The collaboration reflects both firms’ view that Latin American and international wealth markets will increasingly require infrastructure capable of connecting global investment capabilities with local and offshore advisory relationships in a scalable, transparent and flexible format.

About LarrainVial

Founded in Chile in 1934, LarrainVial is a leading Latin American financial services firm with capabilities spanning asset management, wealth management, capital markets, brokerage and third-party investment distribution. The firm has built an extensive regional presence and has continued to expand its distribution capabilities across Latin America, the United States and the U.S. Offshore market. Third-party distribution represents a core pillar of LarrainVial’s business and its strategy of connecting clients with differentiated global investment capabilities.

About inCadense

inCadense® provides technology and services that support asset and wealth managers in designing and delivering managed-account solutions for international investors. Its digital International Turnkey Asset Management Platform, iTAMP®, supports SMAs, UMAs and model portfolios through an integrated architecture spanning multiple custodians, currencies, asset classes and jurisdictions. Through open architecture, global custody and execution connectivity and portfolio implementation capabilities, inCadense helps financial institutions expand managed-account offerings, reduce operational complexity and deliver institutional-quality investment capabilities across international and offshore wealth markets.

Media Contact

A.J. Harper, inCadense Corp., 1 6104257038, aj@incadense.com, www.incadense.com

María Jesús del Pozo, LarrainVial, 56 997057530, mdelpozo@larrainvial.com, www.larrainvial.com

View original content to download multimedia:https://www.prweb.com/releases/larrainvial-and-incadense-join-forces-to-advance-next-generation-wealth-infrastructure-across-latin-america-302862448.html

SOURCE inCadense Corp.

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Unifor welcomes CRTC decision to move forward with Canadian content rules for streaming services

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TORONTO, Aug. 31, 2026 /CNW/ — Unifor applauds the Canadian Radio-television and Telecommunications Commission (CRTC)’s decision to proceed with developing rules that will ensure Canadian programming is available and visible on online streaming services. At the same time, the union is also calling on the federal government to also immediately move ahead with implementing the contributions requirements for digital streamers.

The Commission’s decisive move comes after the issue played a significant role in ending trade talks with the U.S.

“Global streaming companies that profit from Canadian audiences must also contribute to the Canadian broadcasting system and help audiences find Canadian stories,” said Unifor National President Lana Payne.

The CRTC has said it will move forward with regulatory proceedings to determine how individual streaming services will be required to will be required to promote and make Canadian programming discoverable to users. The process implements the Online Streaming Act, which requires streaming services operating in Canada to support access to Canadian programming, including French-language content.

“Strong, enforceable and transparent discoverability rules are essential,” added Payne.

“Canadian content cannot be technically available but effectively buried. The rules must lead to meaningful visibility for Canadian productions and create more job opportunities for the skilled workers who make them.”

Unifor’s media sector has advocated for years for enforceable federal policies to address the crisis facing Canada’s media landscape, including the Digital Services Tax, the Online Streaming Act and the Online News Act. These measures were intended to ensure companies benefiting from access to the Canadian market contributed to the system that supports Canadian stories, journalism and media jobs.

The union continues to support the Online Streaming Act and the Online News Act.

Unifor is urging the federal government and the CRTC to move ahead without delay in implementing the contribution requirements for digital streamers as per the Online Streaming Act, ensuring the final framework includes clear obligations, measurable outcomes, and effective enforcement.

The union will continue to advocate for rules that strengthen Canadian and Indigenous production, protect Canada’s cultural sovereignty, and encourage and sustain good jobs across Canada’s media sector.

Unifor represents more than more than 9,000 media workers in Canada, who perform a diverse range of jobs, including: journalists, printers, advertising representatives, newspaper carriers, video editors, camera operators, technicians, writers, producers, editorial researchers, maintenance workers, on-air talent, stage and film crewmembers, production assistants, website developers, editors and publishers.

Unifor is Canada’s largest union in the private sector, representing 320,000 workers in every major area of the economy. The union advocates for all working people and their rights, fights for equality and social justice in Canada and abroad and strives to create progressive change for a better future.

SOURCE Unifor

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GCW Agency Launches SignlLabs™, A Proprietary A.I. Signaling Practice Built to Earn Brand Visibility Across Artificial Intelligence (AI) Platforms

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New practice gives clients a measurable path to being recommended by ChatGPT, Gemini, Claude, Copilot, and Perplexity, and it is built for AI, not retrofitted from SEO

NEW YORK, Aug. 31, 2026 /PRNewswire/ — Global Communication Works (GCW), the strategic public relations and communications agency, today announced the formation of SignlLabs™, its proprietary AI Signaling practice. SignlLabs gives GCW clients a dedicated methodology for earning visibility and recommendations across leading artificial intelligence platforms, extending the agency’s four decades of earned media expertise to how brands are discovered today.

“For nearly 40 years, GCW has built our clients’ reputations one relationship, one story, and one placement at a time. SignlLabs is the natural next chapter,” said Suzy Ginsburg, Founder and CEO of GCW. Consumers no longer stop at a search engine. They are asking AI platforms for recommendations and answers, and brands need a real strategy to show up there, not a retrofit of old SEO tactics. That is exactly what we built.”

Search engine optimization earns a ranking on a page of links. Answer engine optimization (AEO) earns the snippet an AI reads back. AI Signaling earns the recommendation itself. The gap matters because an AI does not simply answer the question it is asked. It quietly splits a single prompt into roughly five hidden research queries, then composes an answer from the sources it trusts most, which are overwhelmingly earned with third-party endorsements, not a brand’s own website.

Built from the ground up rather than adapted from existing search practices, SignlLabs pairs GCW’s earned media strategy with a dedicated AI recommendation framework, measuring performance across the five platforms most consumers now turn to for answers: ChatGPT, Google Gemini, Claude, Microsoft Copilot, and Perplexity AI. The practice is led by Erika Hanafin Austria, who will work alongside GCW President, Brad Ginsburg and account teams to embed AI Signaling into future client campaigns.

“SEO is about being the answer. AI Signaling is about being the recommendation,” said Erika Hanafin Austria. “When someone asks an answer engine who or what brand is best, the platform runs its own research behind the scenes and names the brands it trusts. That trust lives in earned media, not on a brands homepage. SignlLabs is built for how AI decides, not bolted onto old search tactics.”

Today GCW measures success across both traditional and AI channels, tracking impressions, reach, and engagement alongside AI recommendation lift, so clients see the full picture of how a campaign performs and reaches audiences wherever they get their news and their answers.

SignlLabs is already embedded in GCW campaigns across the agency’s women’s health, consumer health and lifestyle client roster, and the practice will be central to new business pursuits going forward.

For more information about SignlLabs and GCW, visit signllabs.ai. or GCW.AGENCY.

About Global Communication Works (GCW)

GCW is a strategic public relations agency serving clients across women and men’s health, consumer packaged goods, wellness and lifestyle, law and energy. Services span earned media, crisis and reputation management, influencer strategy, film and production, events, media training and AI Signaling. For more information, visit gcw.agency.

About SignlLabs
SignlLabs™ is GCW’s proprietary AI Signaling practice, built to help brands earn visibility and recommendations across leading AI platforms, including ChatGPT, Gemini, Claude, Copilot, and Perplexity. The practice pairs its Signaling Maturity Score™ framework with strategic growth advisory and is available for license by public relations firms, advertising agencies and web development companies for use with their own clients. For more information, visit signllabs.ai.

View original content:https://www.prnewswire.com/news-releases/gcw-agency-launches-signllabs-a-proprietary-ai-signaling-practice-built-to-earn-brand-visibility-across-artificial-intelligence-ai-platforms-302865257.html

SOURCE GCW Partners, LLC

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