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EndoDNA Launches BIOS, Turning Genetic Data Into Living Clinical Intelligence for Precision Medicine

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New platform replaces static, one-time DNA reports with an adaptive dashboard that unifies genomics, biomarkers, and lifestyle data, helping licensed practitioners move from interpretation to action.

STUDIO CITY, Calif., June 16, 2026 /PRNewswire/ — EndoDNA, a precision health intelligence company, today launched BIOS, a patented, intelligent clinical decision-support platform for licensed healthcare practitioners. BIOS replaces the company’s legacy interpretation engine, myDNALive, giving functional, integrative, regenerative, hormone-optimization, and longevity practitioners a continuous, longitudinal view of each patient’s biology.

BIOS, short for Biomedical Reasoning and Adaptive Inference Network, moves precision medicine past static, one-time genetic reports. In their place, it provides an adaptive dashboard that brings together genomics, biomarkers, lifestyle inputs, symptoms, and ongoing patient data.

“For years, clinicians have had access to more biological data than ever before, but very few tools to help them actually apply it,” said Len May, Founder and CEO of EndoDNA. “Most genetic platforms stop at information. BIOS was built to answer the question clinicians are really asking: ‘Now what?’ It transforms complex biology into structured clinical insight that evolves alongside the patient; helping providers move from interpretation to action with greater clarity and consistency.”

Beyond isolated SNPs: built around biological pathways

Unlike consumer DNA platforms or general-purpose AI tools, BIOS is built around interconnected biological pathways rather than isolated single-nucleotide polymorphism (SNP) interpretation. It maps genomic data across vital systems, including:

Hormone metabolism and metabolic signalingInflammation and stress responseNeurotransmitter regulation and cognitive function

In all, BIOS analyzes approximately 1 million validated variants across 21 pathway systems, with 214 pathways actively curated for real-time clinical decision support.

How BIOS works: four connected memory networks

BIOS doesn’t read a single data point in isolation. It reasons across four connected memory networks that build a fuller picture of each patient over time:

World: integrates population-level genomic evidence from sources like biobanks, CPIC, and PharmGKB.Experience: draws on aggregated practitioner case history to surface what has worked for similar patients.Opinion: captures a practitioner’s own notes and overrides to refine and personalize recommendations.Observation: tracks patient-reported outcomes and biomarker trends over time.

Through a single, HIPAA-compliant dashboard, licensed practitioners can order DNA tests, generate unlimited specialized reports from existing genotype files, integrate biomarker and lab data, analyze pharmacogenomic interactions, and query patient genomic data using natural-language search.

Available report categories include Female and Male Regenerative Health, NeuroDNA Cognitive & Neurological Health, Nutrigenomics & Metabolic Pathway Analysis, Endocannabinoid System (ECS) Panels, and Hormone Optimization & Longevity Pathways.

“For years, clinicians have had access to more data than they could reasonably interpret. What has been missing is a reliable way to translate that information into clinical action” says Dr. Allen Lawrence, MA, MD, PhD. “EndoDNA and BIOS help solve that problem by transforming complex genomic and biological inputs into organized, actionable intelligence. The result is a more scalable precision medicine model; one that allows providers to make better-informed decisions, improve patient engagement, and deliver truly personalized care more efficiently.”

A track record of accuracy and patented innovation

Since its founding, EndoDNA has served more than 10,000 patients across 9+ countries through CAP/CLIA-accredited laboratory partners. Using Illumina next-generation sequencing, the company delivers a 99.6% genotyping accuracy rate. EndoDNA holds more than 10 issued and pending patents, including the industry’s only patented methodology for genotyping the endocannabinoid system (ECS), and a patented machine-learning methodology for predicting efficacy from genetic and biometric data.

BIOS is available immediately to licensed healthcare practitioners as a clinical decision-support and research-use platform.

About EndoDNA

EndoDNA is a precision health intelligence company combining genomic sequencing, patented intelligent clinical decision support, and longitudinal biological reasoning for licensed healthcare practitioners. Powered by BIOS, the platform helps clinicians translate genetic and biological data into structured clinical insight across hormone optimization, regenerative medicine, cognitive health, metabolic function, nutrigenomics, and longevity care; supporting pathway-level precision while preserving practitioner-led judgment. Learn more at www.EndoDNA.com.

View original content:https://www.prnewswire.com/news-releases/endodna-launches-bios-turning-genetic-data-into-living-clinical-intelligence-for-precision-medicine-302801069.html

SOURCE EndoDNA

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APPOINTMENT OF CHAIRMAN OF THE AUDIT COMMITTEE

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JOHANNESBURG, Nov. 13, 2026 /PRNewswire/ — In compliance with para 6.71 of the JSE Listings Requirements and para 6.42 of the JSE Debt and Specialist Securities Listings Requirements, Sasol is pleased to announce the appointment of Mr Stanley Subramoney as the Chairman of the Audit Committee and Sasol’s financial expert with effect from 14 November 2026.

Mr Subramoney has been an independent non-executive director of Sasol Limited since 2021 and is a member of the Audit and Remuneration Committees. He is a chartered accountant with extensive experience in accounting, auditing and international business. During a 27-year career with PwC, he served as an audit and advisory partner and Deputy Chief Executive Officer of PwC Southern Africa. He gained significant international exposure through complex assignments and global organisational roles. He is currently Chief Executive Officer of Menston Holdings, a diversified investment company. He serves as an independent non-executive director of Nedbank Group, where he formerly chaired the Group Audit and Credit Committees.

The Chairman of the Sasol Board, Ms Muriel Dube, said: “Stanley has been a valued member of the Sasol Board and Audit Committee since 2021. His extensive accounting and audit expertise, together with his deep knowledge of Sasol gained during his tenure on the Board, position him well to lead the Audit Committee. The Board is confident that he will provide strong leadership to the Committee and continue to make a valuable contribution to Sasol.”

For further information, please contact:
Sasol Investor Relations,
Tiffany Sydow, VP Investor Relations
Telephone: +27 (0) 71 673 1929
investor.relations@sasol.com

 

View original content:https://www.prnewswire.com/news-releases/appointment-of-chairman-of-the-audit-committee-302938758.html

SOURCE Sasol Limited

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CCTV4: The special coverage APEC: Shenzhen Engagement will air

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BEIJING, Nov. 13, 2026 /PRNewswire/ — The 2026 APEC Summit will be held in Shenzhen, Guangdong Province, on November 18–19, attracting global attention. China Media Group’s Chinese Global Program Center has set up a front-line studio in Shenzhen. From November 13 to 19, China News will launch the special coverage APEC: Shenzhen Engagement in its flagship noon and evening slots. Adopting an international perspective and centered on the theme of “Building an Asia-Pacific Community for Common Prosperity”, the special coverage will present a comprehensive and multi-dimensional picture of the APEC Summit in Shenzhen through a rich array of reporting formats, including live broadcasts, studio discussions, high-profile interviews, and integrated-media live streams.

Guests from the China (Shenzhen) Development Institute and other institutions will be invited to the studio to discuss new models of global governance under the APEC cooperation framework amid key summit topics.

APEC Face to Face, a high-end interview segment, will feature exclusive conversations with attending dignitaries, senior officials of APEC economies, industry leaders, business figures, heads of multinational corporations and authoritative think tank experts. It combines dedicated in-depth interviews with on-the-spot interviews to capture hot topics of Asia-Pacific cooperation.

The integrated-media program Shenzhen’s New Landmarks uses six core landmark clusters across Shenzhen as its narrative thread. It integrates mobile live streaming, immersive exploration, feature videos and in-depth interviews to offer a panoramic view of Shenzhen’s development achievements and practical experience as a pioneer of China’s reform and opening up and a core engine of the Guangdong-Hong Kong-Macao Greater Bay Area.

The special coverage APEC: Shenzhen Engagement will air on China Media Group’s CCTV-4 (Chinese International Channel) at 12:00 and 18:00 from November 13 to 19. Stay tuned!

View original content to download multimedia:https://www.prnewswire.com/apac/news-releases/cctv4-the-special-coverage-apec-shenzhen-engagement-will-air-302938759.html

SOURCE CCTV4

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Bracco and Avicenna.AI Announce FDA Clearance for UPTUNITY™ | Aneurysm, a New AI-Enabled Software for Brain Aneurysm Detection and Assessment

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Developed in collaboration with Avicenna.AI, the newly FDA-cleared technology introduces UPTUNITY™, Bracco’s new portfolio of AI-enabled clinical decision support solutions.

MILAN, Nov. 13, 2026 /PRNewswire/ — Bracco and Avicenna.AI today announced U.S. Food and Drug Administration (FDA) 510(k) clearance of UPTUNITY™ | Aneurysm, the first offering within the new UPTUNITY™ portfolio and a result of Bracco’s collaboration with Avicenna.AI. Designed to support medical specialists in detecting and assessing brain aneurysms on cerebral arteries computed tomography angiography (CTA) images, UPTUNITY | Aneurysm integrates AI assistance into the radiologist’s reading workflow.

UPTUNITY reinforces Bracco’s Digital Health strategy by expanding the company’s capabilities into interpretive AI. The portfolio provides clinical decision support capabilities for specific needs in image interpretation. It complements Bracco’s existing AI offerings, including AiMIFY®, developed with Subtle Medical, which applies AI to amplify existing contrast enhancement in brain MRI for improved lesion visualization.1 With UPTUNITY, Bracco continues to invest in Digital Health technologies that extend its support for radiologists across the imaging continuum and advance innovation beyond contrast agents.

“A small incidental aneurysm on a head CTA can easily be overlooked when the worklist keeps growing,” said Cosimo DePinto, Executive Vice President, Marketing & Commercial Operations, Bracco Americas. “UPTUNITY | Aneurysm works inside the reading environment radiologists already know and helps find the aneurysm hiding in the CT scan. The clinical decision stays where it belongs: with the radiologist.”

An estimated one in 50 U.S. adults has an unruptured brain aneurysm, a condition that is often asymptomatic.2 Aneurysms can be difficult to detect on cerebral arteries CTA and may be discovered incidentally during imaging performed to evaluate other clinical concerns.3,4 For known aneurysms, consistent follow-up and assessment of changes in growth are important to ongoing clinical evaluation.4

UPTUNITY | Aneurysm spans brain aneurysm detection and ongoing follow-up across the radiologist’s workflow. For detection, the computer-assisted detection (CADe) and diagnosis (CADx) software is intended for use as a concurrent reading aid by appropriately trained medical specialists. It identifies suspected saccular brain aneurysms greater than 3 mm on head CTA images and provides information about their presence, location and size for assessment and characterization. For known aneurysms, the follow-up functionality (MIMPS) provides quantitative measurements and comparison between examinations to assess changes over time. The integrated workflow extends from initial identification through longitudinal follow-up.

The software provides information for use alongside review of the CTA images, while maintaining physician control over clinical decision-making. It is not intended to replace a full patient evaluation or a qualified physician’s review and should not be solely relied upon to make or confirm a diagnosis.5,6

“For a patient with an unruptured aneurysm, the follow-up scan always brings the same question: has it changed?” said Fabio Tedoldi, PhD, Head of Global Research & Development, Bracco Imaging. “UPTUNITY | Aneurysm supports physicians from first detection through subsequent monitoring, with comparable readings at every exam. Precision, to us, means not only finding, but following up.”

Bracco and Avicenna.AI announced their strategic partnership in March 2026 to advance AI applications in contrast-enhanced computed tomography. The companies are now preparing for the commercial introduction of UPTUNITY | Aneurysm in the United States. Avicenna.AI will lead promotion and commercial distribution of the solution.

“Contrast agents were created to make the invisible visible. A brain aneurysm is exactly that kind of hidden finding: silent, often discovered by chance, then followed millimeter by millimeter for years. Bracco has spent decades lighting up the vessels. But an image only helps if what it shows is seen. Avicenna.AI brings AI assistance to those images, helping radiologists detect an aneurysm >3 mm and track how it changes over time,” said Cyril Di Grandi, CEO and co-founder, Avicenna.AI. “UPTUNITY | Aneurysm combines these two strengths, turning a head CTA into a story the radiologist can follow, from the first finding through every follow-up. Neither of us could have done this alone, and that is the point of this partnership.”

UPTUNITY | Aneurysm will be showcased at the Radiological Society of North America (RSNA) 2026 Annual Meeting, taking place November 29–December 3 in Chicago. To learn more about Bracco’s presence at RSNA 2026, including UPTUNITY | Aneurysm and the company’s vision for artificial intelligence, visit www.bracco.com/RSNA.

UPTUNITY | Aneurysm has received 510(k) clearance from the U.S. Food and Drug Administration under K262062 and K262147. UPTUNITY™ | Aneurysm Detection and UPTUNITY™ | Aneurysm Management are the commercial names for CINA-Aneurysm (K262062) and CINA-Aneurysm+ (K262147), respectively. For complete operating instructions, warnings, precautions and other important safety information, refer to the instructions for use.

About Bracco
Bracco Group, founded in 1927, is a global leader in diagnostic imaging committed to advancing healthcare and improving people’s lives by shaping the future of prevention and precision medicine. The company operates in the healthcare sector in more than 100 countries, with a workforce of over 4,000 employees and consolidated annual revenues of approximately €2 billion, with a global footprint.

With a strong commitment to innovation, investing around 9% of its reference turnover in research and development, Bracco develops and provides a broad portfolio of pharmaceutical products for diagnostic imaging, including contrast agents for X-ray, computed tomography and magnetic resonance imaging, as well as microbubbles for contrast-enhanced ultrasound and molecular imaging agents such as radioactive tracers and novel positron emission tomography imaging agents, alongside artificial intelligence-based solutions. It is also a global market leader in advanced contrast management technologies for cardiovascular angiography and radiology imaging. Discover more at www.bracco.com.

About Avicenna.AI
Founded in 2018, Avicenna.AI specializes in the development of artificial intelligence solutions dedicated to emergency and incidental medical imaging, using deep learning techniques to identify, detect and quantify critical pathologies from CT images. Co-founded by Cyril Di Grandi, co-founder of Olea Medical, and Dr. Peter Chang, American radiologist and AI expert, Avicenna.AI’s mission is to support radiologists’ diagnosis, ensure faster and more reliable detection of serious pathologies, and improve the quality of patient care through its AI tools for radiology. For more information, follow us on LinkedIn and visit our website: www.avicenna.ai

Media Contacts:

Bracco Press Contact
Alessandra Vulpiani
Bracco Imaging, Senior Marketing Communication Manager
Alessandra.Vulpiani@bracco.com

Avicenna.AI Press Contact
Stéphanie Bellavia
Avicenna.AI, Marketing Manager
stephanie.bellavia@avicenna.ai

1Venkata SP, Arnold TC, Serra SC, et al. Deep-Learning Based Contrast Boosting: A Multi-Center Multi-Reader Study on Clinical Performance With Standard Contrast Enhanced Brain MRI. J Magn Reson Imaging. 2026:1-15. doi:10.1002/jmri.70460.
2Brain Aneurysm Foundation. Brain Aneurysm Statistics and Facts. Available at: https://www.bafound.org/statistics-and-facts/. Accessed October 28, 2026.
3Biddle G, Assadsangabi R, Broadhead K, Hacein-Bey L, Ivanovic V. Diagnostic Errors in Cerebrovascular Pathology: Retrospective Analysis of a Neuroradiology Database at a Large Tertiary Academic Medical Center. AJNR Am J Neuroradiol. 2022;43(9):1271-1278. doi:10.3174/ajnr.A7596
4Thompson BG, Brown RD Jr, Amin-Hanjani S, et al. Guidelines for the Management of Patients With Unruptured Intracranial Aneurysms: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2015;46(8):2368-2400.
5U.S. Food and Drug Administration. 510(k) Summary K262062, CINA-Aneurysm.
6U.S. Food and Drug Administration. 510(k) Summary K262147, CINA-Aneurysm+.

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