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Cumulus Neuroscience Presents Data at AAIC 2026 Annual Meeting Showing a Two-Minute Digital Task Matches or Outperforms Clinical Benchmarks for Alzheimer’s Trial Pre-enrichment

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Across three independent studies, the NeuLogiq® Platform two-minute tablet-based Symbol Swap task delivered clinically meaningful discrimination between control, MCI and Alzheimer’s dementia groups and detected blood-biomarker-defined pathology — including in clinically normal individuals — with accuracy matching or exceeding the ADAS-Cog, MoCA and MMSE benchmarks.

LONDON, July 15, 2026 /PRNewswire/ — Cumulus Neuroscience (Cumulus; The Company), a global digital health company focused on advancing neuroscience clinical trials and patient care through improved data, today presented data on its Symbol Swap digital cognitive task at the Alzheimer’s Association International Conference 2026. The poster titled, ‘A Brief Digital Symbol-Coding Task Outperforms Clinical Benchmarks for Alzheimer’s Trial Pre-enrichment,’ reports interim data on Symbol Swap — a two-minute, tablet-based implementation of the classic Symbol Coding (Digit Symbol Substitution) Task that measures executive function — across one completed at-home study and two large in-clinic studies.

Across three independent studies, Symbol Swap matched or exceeded the pre-enrichment performance of established clinical cognitive screeners in just two minutes, delivering clinically meaningful discrimination between control, MCI and Alzheimer’s dementia groups while dramatically reducing participant and site burden. It showed robust associations with biomarker-defined Alzheimer’s pathology (blood plasma pTau-217), even in clinically normal individuals who would typically score well on standard tests — suggesting it could flag those most likely to be amyloid- or tau-positive and improve the efficiency of downstream plasma, PET or CSF screening. Digitally administered and automatically scored, Symbol Swap scales readily across large, multi-site trials in both in-clinic and at-home workflows, making it an attractive first-line enrichment filter — preceding plasma biomarkers or feeding composite digital endpoints — with the potential to cut screen-failure rates and accelerate recruitment into Alzheimer’s trials.

“It is striking that a two-minute, patient-friendly task can match or beat assessments that take a trained clinician 10 to 45 minutes to administer— and that it picks up Alzheimer’s pathology even in study participants who look cognitively normal on standard tests,” said Brian Murphy, PhD, Cumulus Co-Founder and CSO. “This data confirms that Symbol Swap may be a powerful first-line filter, preceding plasma biomarkers or feeding a multimodal composite. We are grateful to all the study participants and research collaborators who made these important findings possible.”

Symbol Swap was evaluated in CNS-101, a first-of-its-kind validation study that measured functional neurophysiology with the NeuLogiq Platform at home in patients living with mild Alzheimer’s dementia and healthy controls (compared with the ADAS-Cog); the Fastball i4i study (in-clinic; compared with the MoCA); and the Global Alzheimer’s Platform (GAP) BioHermes-002 study (20 sites across the US, Canada and Europe; compared with the MMSE). Pathology status in CNS-101 and the Fastball i4i study was defined by the AlzPath phosphorylated-tau 217 assay. Data presented from the Fastball i4i study and BioHermes-2 study are interim.

“The Bio-Hermes-002 study is focused on enrolling participants with or without memory concerns to help evaluate blood or digital tests that may help identify the presence of amyloid plaques or tau tangles in the brain, the hallmark pathologies associated with Alzheimer’s disease,” said Lammert Albers, Chief Commercial Officer for GAP. “The data presented by Cumulus suggests that digital assessments, including Symbol Swap, may help identify individuals who are more likely to have underlying Alzheimer’s pathology and could support more efficient selection of participants for follow-up blood-based biomarker testing. This approach has the potential to shorten enrollment timelines and lower screening costs.”

A second poster featuring NeuLogiq data titled ‘Multi-domain Digital Endpoints for Decentralized Alzheimer’s Trials: Experience from the CNS-101 Study (NeuLogiq®),’ was presented by Dr. James Rowe, Professor of Cognitive Neurology at the University of Cambridge and Principal Investigator on CNS-101. This study confirmed NeuLogiq Platform cognitive and EEG assessments were well tolerated by study participants, and their sensitivity could enable smaller, more efficient trials.

“Alzheimer’s trials have long depended on assessments that are burdensome for participants and difficult to use at scale,” said Dr. James Rowe, Professor of Cognitive Neurology at the University of Cambridge and Principal Investigator on CNS-101. “In CNS-101 we found that multi-domain digital cognitive and EEG measures from the NeuLogiq Platform were well tolerated by people living with Alzheimer’s disease and sensitive enough to capture meaningful change. That sensitivity makes it possible to design smaller, more efficient trials — reducing the burden on patients while lowering the time and cost to test new therapies.”

“Getting the right participants into trials is one of the most expensive and frustrating bottlenecks in Alzheimer’s drug development today,” said Tina Sampath, CEO of Cumulus. “A low-cost, patient-friendly, automatically scored task that runs at home or in clinic, and points to who is most likely to be biomarker-positive, has real potential to cut screen-failure rates and ease the burden on patients and sites. The two posters presented at AAIC tell a connected story: alongside Symbol Swap’s power to enrich at the front end, our CNS-101 data show that NeuLogiq’s multi-domain cognitive and EEG endpoints are well tolerated and sensitive enough to enable smaller, more efficient trials — together, that’s a path to substantially reducing the cost and timeline of every study where they’re deployed.”

Cumulus supports precision in CNS clinical trials for its industry partners by enabling remote monitoring of patients across multiple domains of brain function. To learn more, visit www.cumulusneuro.com.

About Cumulus Neuroscience

With a mission to generate the data and insights required to accelerate diagnosis and management of central nervous system (CNS) disorders for millions of patients and caregivers around the world, Cumulus Neuroscience is advancing NeuLogiq®, an AI-based, multi-domain digital biomarker platform to enable better, faster decision making in neurology and neuropsychiatry clinical trials and patient care. Designed for and with 10 of the world’s leading pharma companies, the platform enables decentralized trials and is already making a difference in the development of therapies for Alzheimer’s Disease, depression and schizophrenia.

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Tecpinion Launches Sweepstakes Industry Analysis Report 2026, Covering Market Insights, Growth, Regulation, Technology and Industry Future

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5 hours ago

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September 26, 2026

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Tecpinion’s 2026 report examines U.S. sweepstakes growth, rules, technology and future scenarios.

MIAMI, Sept. 26, 2026 /PRNewswire-PRWeb/ — Tecpinion, a GLI-19 iGaming platform provider delivering technology solutions across iGaming, sweepstakes, prediction markets and other digital gaming verticals, today announced the launch of its new industry report, “Sweepstakes Industry Analysis 2026: Market Dynamics, Trends & Forecast.”

Sweepstakes industry Report 2026 – Latest Insights into Market Growth, Regulation, Technology and the Future of the sweepstakes/social Industry

The report is designed not only to examine where the sweepstakes industry stands today, but also to share practical market insights and contribute to a more informed industry conversation as the sector continues to evolve.

The research provides a detailed assessment of the U.S. sweepstakes ecosystem, covering market structure, consumer behaviour, business economics, regulation, technology, payments, customer acquisition, competitive dynamics and the 2026–2030 outlook. It spans 16 analytical sections, five market segments and 12 U.S. states, supported by nine strategic exhibits and 21 primary, regulatory, standards and company sources.

As the industry moves from experimentation toward greater professionalisation, the report highlights a shift in competitive priorities. Launch speed alone is becoming less important as operators increasingly need to balance customer acquisition, retention, payment reliability, fraud prevention, promotional costs, regulatory requirements and consumer trust.

A Sneak Peek at the Report

One of the report’s key observations is that a single official market-size figure cannot accurately capture the sweepstakes industry. Different estimates can cover very different segments. Rather than presenting an unsupported headline number, the report takes a segmented, scenario-based approach to understanding the market.

The report identifies five key segments: promotional sweepstakes, social casino, sweepstakes casino, prize-based gaming and B2B sweepstakes technology.

Technology is also becoming a major competitive layer. Modern platforms increasingly depend on PAM, payments, identity and age verification, geolocation, fraud detection, CRM, analytics, game aggregation and security. The report also explores practical AI applications, including LTV prediction, churn analysis, player segmentation, fraud detection, forecasting and customer support.

Regulation remains another defining factor. The report assesses 12 U.S. states, examining regulatory attention and legislative activity while highlighting the importance of jurisdiction-specific analysis.

Looking ahead, the report presents four 2026–2030 scenarios – professionalisation, high growth, regulatory constraint and technology-driven growth, and explores how regulation, technology, payments, trust and customer economics could shape the industry’s next phase.

Knowledge Sharing at the Core

For Tecpinion, the report is also about sharing knowledge, not just presenting data.

“We believe the industry grows stronger when knowledge is shared. Sweepstakes is evolving quickly, and operators and technology providers are facing many of the same questions around regulation, technology, payments, customer acquisition, trust and long-term sustainability. By sharing our research and observations, we want to contribute to a more informed industry where businesses can learn from one another, innovate responsibly and build for the long term.” said [Manoj Trivedi, Co-Founder & CSMO, Tecpinion].

The publication forms part of Tecpinion’s broader commitment to industry research, thought leadership and knowledge sharing across the evolving digital gaming ecosystem.

Access the Full Report

The full “Sweepstakes Industry Analysis 2026: Market Dynamics, Trends & Forecast” is now available for operators, technology providers, affiliates, investors and industry professionals looking to understand the trends, challenges and opportunities shaping the market.

👉 [Explore the Full Report]

About Tecpinion

Tecpinion is a GLI-19 iGaming platform provider delivering technology solutions across online casino, sportsbook, sweepstakes, prediction markets, social gaming and emerging gaming verticals. Its offerings include full source code, iGaming platform development, PAM, game aggregation, payment solutions, KYC, geolocation, fraud prevention, CRM, bonuses and promotions, affiliate management, analytics, responsible gaming, security and compliance technology.

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Manoj Trivedi, TECPINION, 91 9926504499, sales@tecpinion.com, https://www.tecpinion.com/ 

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Agoda Unveils 2026 Return Visitor Ranking: Tokyo Is Asia’s Most Revisited City

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10 hours ago

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September 26, 2026

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SINGAPORE, Sept. 26, 2026 /PRNewswire/ — Digital travel platform Agoda has unveiled its latest Repeat Visitor Ranking, highlighting the top 10 destinations across Asia that keep travelers coming back for more. Based on bookings made during the first half of the year, Agoda reveals that Tokyo has claimed the top spot for the first time, overtaking Bangkok. Rounding out the top five are Bali—ranking third place for the first time—followed by Seoul and Osaka. Da Nang, Kuala Lumpur, Fukuoka, Taipei, and Johor Bahru complete the top 10 list.

Some destinations have a way of calling travelers back for more. The chance to discover new attractions, revisit fond favorites, or simply enjoy the familiar surroundings keeps travelers booking again and again. Agoda’s data shows that these beloved places often attract repeat visits, with some travelers returning multiple times in just the first half of the year.

Tokyo’s rise to number one reflects its unique ability to offer something new with each visit, from seasonal spectacles like cherry blossoms to hidden neighborhoods and an unmatched culinary scene. Bangkok, ranking second, continues to captivate with its unparalleled wellness experiences, world-class dining, and cultural landmarks. Bali’s climb to third place underscores the island’s magnetic appeal with its irresistible beaches, spiritual retreats, and lush landscapes that enchant travelers time and again.

This year’s ranking also reveals the rising appeal of Japan and Vietnam as increasingly popular places people love to revisit. Beyond Tokyo’s ascent to the top, Fukuoka has entered the top 10 for the first time at number eight, signaling travelers’ desire to explore beyond Japan’s traditional tourist hubs to experience Fukuoka’s renowned ramen culture and laid-back atmosphere. Meanwhile, Vietnam’s Da Nang has climbed two spots to sixth place, with its stunning beaches, proximity to UNESCO sites like Hoi An, and excellent value drawing visitors back repeatedly.

Andrew Smith, Senior Vice President, Supply at Agoda, shared, “Asia is home to so many destinations that are worth revisiting, and what we’re seeing is that travelers are building relationships with their favorite cities. The shift with Tokyo’s rise to number one and destinations like Fukuoka and Da Nang gaining ground show that travelers are finding new reasons to return, whether it’s seasonal attractions, undiscovered neighborhoods, or simply great food. At Agoda, we’re here to make those return trips easy and rewarding.”

For travelers looking to revisit their favorite destinations or discover new ones, Agoda offers over 6 million holiday properties, more than 130,000 flight routes, and over 300,000 activities, all of which can be combined in a single booking. Visit the website at www.Agoda.com or download the mobile app for the best deals.

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SOURCE Agoda

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FDIC Appoints Sunwest Bank as Nano Banc’s Acquiring Institution

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11 hours ago

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September 26, 2026

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IRVINE, Calif., Sept. 25, 2026 /PRNewswire/ — Sunwest Bank has acquired Nano Banc of Irvine, California in an FDIC-assisted acquisition. The Federal Deposit Insurance Corporation (FDIC) accepted receivership of Nano Banc from the Department of Financial Protection and Innovation (DFPI), which closed Nano Banc on Friday, September 25th. The FDIC subsequently entered into an agreement with Sunwest Bank, under which Sunwest agreed to acquire substantially all the deposits and a portion of assets of Nano Banc. The assumed deposits total approximately $605 million and assumed loans total $227 million.

Nano Banc customers will have immediate access to their deposits. Over the weekend, they can access their deposits by writing checks, using ATMs or through their debit cards. Checks drawn on Nano Banc will continue to be processed. All loan customers should continue to make their payments as usual. The former Nano Banc will reopen as Sunwest Bank on Monday, September 28th.

“We are honored to once again to be selected by the FDIC as the acquiring institution of an FDIC-assisted acquisition, marking the sixth time Sunwest Bank has completed such a transaction,” said Carson Lappetito, President and CEO of Sunwest Bank. “This opportunity reflects the financial strength, disciplined management, and stability that have defined Sunwest Bank for more than five decades. We are excited to welcome Nano Banc’s customers to Sunwest and show them the high-touch service, advanced technology and sophistication we offer to our clients.”

Customers with questions should contact the FDIC toll-free at 1-866-314-1744 or visit the FDIC Website at FDIC.GOV. This phone number will be operational this evening until 8:00 p.m., Pacific Time (PT); on Saturday from 9:00 a.m. to 5:00 p.m., PT; Sunday from noon to 12:00 p.m. to 4:00 p.m., PT; Monday from 8:00 a.m. to 5:00 p.m., PT, and thereafter, weekdays from 8:00 a.m. to 4:00 p.m., PT. 

About Sunwest Bank

Founded in 1969, Sunwest Bank is a privately held commercial bank with over $5.0 billion in assets. With a growing presence throughout the United States, Sunwest is headquartered in Sandy, Utah, with offices across California, Arizona, Idaho, Colorado, Utah, and Florida. The bank partners with businesses,

individuals, and entrepreneurs nationwide to deliver leading banking services including technology forward treasury management, commercial and real estate lending products, and corporate financial solutions.

With a strong capital position and a commitment to innovation, Sunwest Bank continues to challenge traditional banking models through forward-thinking initiatives designed to support its clients’ growth and long-term success. Sunwest Bank operates with a Fortress Balance Sheet, long-term outlook, and has an impeccable track record of supporting their clients through all economic cycles.

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SOURCE Sunwest Bank

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