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Synoligo Biotechnologies and Lumiphore Announce a Partnership to Provide [Time-Resolved] Luminescent Oligos and Assays for the Nucleic Acid Amplification Testing Market (NAAT)

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The partnership aims to provide game-changing luminescent lanthanide-based oligo probes for diagnostics and life science research applications.

MORRISVILLE, N.C. and BERKELEY, Calif., May 19, 2025 /PRNewswire/ — Synoligo Biotechnologies Inc. and Lumiphore Inc. announced they have entered into a partnership to incorporate Lumiphore’s luminescent lanthanide reporter technology conjugated to Synoligo’s oligonucleotide offerings for diagnostic tests and use in life science research.

Under the partnership, Synoligo Biotechnologies has the non-exclusive rights to incorporate Lumiphore’s technology into future diagnostic tests and life science (RUO) assays. Lumiphore’s goal is to bring the benefits of luminescent lanthanide-based assays, known as time-resolved Förster resonance energy transfer (TR-FRET) assays, to the NAAT diagnostic and research market.

“Synoligo is positioned as a market leader in Dual Labeled Quenched Probe manufacturing. This potent and unique synergy with Lumiphore explores the use of lanthanides in real-time and time-resolved genomic applications” said Marc Beal Director of Business Development at Synoligo.  

The patented Lumi804-Eu Lanthanide probe at the center of this technology exhibits excellent photostability, resistance to ozone, and bright/narrow Eu(III)-centered emission at 613 nm. The excitation wavelength is flexible (300-400 nm), and the brightness is insensitive to changes in pH (from 2-12). While competitive at steady-state with standard fluors, the real advantage comes from enabling time-resolved detection. The long emission lifetime (716 µs) can be used to generate ultra low-background, high-throughput TR-FRET assays, eliminating wash steps and simplifying analyte preparation.

“Our game-changing luminescent oligo detection brings new assays into the global NAAT market estimated to be $8.1-billion in 2025 growing to $16-19-billion in 2030. The major market focus has been on infectious disease and has been moving into oncology and genetic testing” said Steve Blose Chief Business Officer at Lumiphore.

To learn more about the product or request a quote, visit:

https://synoligo.com/lumi804-eu-an-exceptional-lanthanide-probe-for-time-resolved-photoluminescence/

About Synoligo Biotechnologies, Inc.

Headquartered in Morrisville, NC, USA, Synoligo Biotechnologies is a Contract Research and Development Organization (CRDO) specialized in manufacturing complex and highly modified oligonucleotide for academic, biotech start-up and large pharmaceutical communities. Synoligo is a leading oligonucleotide manufacturing company providing high quality, cost-effective custom oligonucleotides at varying scales for research, diagnostic, and therapeutic applications.

About Lumiphore, Inc.

Based in Berkeley, California, Lumiphore Inc., is a biotechnology leader in the development of proprietary luminescent lanthanide reporters and radionuclide payload delivery technology, for use in high-value diagnostics and site-directed radio-pharmaceutical applications. The company’s technology was first developed in the laboratory of Professor Kenneth N. Raymond at the University of California, Berkeley, a world expert on lanthanide coordination chemistry.

View original content to download multimedia:https://www.prnewswire.com/news-releases/synoligo-biotechnologies-and-lumiphore-announce-a-partnership-to-provide-time-resolved-luminescent-oligos-and-assays-for-the-nucleic-acid-amplification-testing-market-naat-302458362.html

SOURCE Synoligo Biotechnologies Inc.

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Nelnet Campus Commerce Named Top Higher Education Payment Solutions Provider by Education Technology Insights

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LINCOLN, Neb., May 5, 2026 /PRNewswire/ — Nelnet Campus Commerce, a division of Nelnet, Inc. (NYSE: NNI), announced it has been named Top Higher Education Payment Solutions Provider for 2026 by Education Technology Insights, a leading education technology publication. The recognition highlights payment providers making a measurable impact on how colleges and universities manage, process, and protect student-facing financial transactions.

This designation marks the second time in three years that Nelnet Campus Commerce has been honored by the Education Technology Insights publisher family. In 2023, sister publication Enterprise Security Magazine named Nelnet Campus Commerce a Top Payment Security Solutions Provider, reinforcing the company’s sustained focus on building secure, fully integrated payment technology for higher education.

Education Technology Insights is a monthly print and digital publication reaching more than 127,000 qualified subscribers. Honorees are selected through a structured evaluation process that includes subscriber nominations, editorial research, and review by an industry advisory panel.

For nearly 25 years, Nelnet Campus Commerce has maintained the highest levels of payment security and compliance in higher education, including Payment Card Industry (PCI) Level 1 validation, Point-to-Point (P2PE) Encryption, Family Educational Rights and Privacy Act (FERPA) compliance, and Nacha (the electronic payments association) Verified status. These credentials, combined with deep integrations across all major Enterprise Resource Planning (ERP) systems, have made Nelnet Campus Commerce a trusted partner for more than 1,100 higher education institutions navigating an increasingly complex payments landscape.

“Being recognized by Education Technology Insights, and by the same publisher that recognized our payment security leadership in 2023, reflects the sustained commitment our team brings to this work every day,” said Jackie Strohbehn, President of Nelnet Campus Commerce. “Higher education institutions deserve platforms that are not only flexible and intuitive for students and payers, but fundamentally secure. This recognition affirms that we are delivering on both, and we are grateful to our partner institutions who trust us to support their students and operations.”

The full editorial profile of Nelnet Campus Commerce is available on the Education Technology Insights website.

About Nelnet Campus Commerce
Nelnet Campus Commerce delivers unlimited payment opportunities across campus. Solutions use the latest technology to create a unique and integrated payment experience for more than 1,100 higher education institutions across the country. The intuitive and secure solutions are PCI Level 1 validated and integrate with every major ERP system. From payment processing and refunds to tuition payment plans and online storefronts, Nelnet Campus Commerce helps process every payment on campus. For more information, visit CampusCommerce.com.

View original content:https://www.prnewswire.com/news-releases/nelnet-campus-commerce-named-top-higher-education-payment-solutions-provider-by-education-technology-insights-302762821.html

SOURCE Nelnet Campus Commerce

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Cboe Global Markets Reports Trading Volume for April 2026

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CHICAGO, May 5, 2026 /PRNewswire/ — Cboe Global Markets, Inc. (Cboe: CBOE), a leading global markets operator and pioneer in equity derivatives, today reported April trading volume statistics across its global business lines.

The data sheet “Cboe Global Markets Monthly Volume & RPC/Net Revenue Capture Report” contains an overview of certain April trading statistics and market share by business segment, volume in select index products, and RPC/net capture, which is reported on a one-month lag, across business lines.

Average Daily Trading Volume (ADV) by Month

Year-To-Date

Apr

2026

Apr

2025

%

Chg

Mar
2026

%  
Chg

Apr

2026

Apr

2025

%  
Chg

Multi-listed options (contracts, k)

14,374

13,260

8.4 %

14,203

1.2 %

14,051

13,372

5.1 %

Index options (contracts, k)

6,257

5,087

23.0 %

6,876

-9.0 %

6,167

4,853

27.1 %

Futures (contracts, k)1

222

309

-28.0 %

338

-34.1 %

268

265

1.1 %

U.S. Equities – On-Exchange (matched shares, mn)

1,677

2,118

-20.8 %

2,048

-18.1 %

1,890

1,765

7.1 %

U.S. Equities – Off-Exchange (matched shares, mn)

220

125

75.7 %

240

-8.4 %

242

100

142.8 %

Canadian Equities (matched shares, k)

195,488

170,517

14.6 %

203,135

-3.8 %

210,630

162,357

29.7 %

European Equities (€, mn)

16,624

17,410

-4.5 %

18,629

-10.8 %

17,122

14,684

16.6 %

Australian Equities (AUD, mn)

1,125

1,047

7.4 %

1,318

-14.7 %

1,181

873

35.3 %

Global FX ($, mn)

57,873

65,340

-11.4 %

79,865

-27.5 %

67,171

55,398

21.3 %

Cboe Clear Europe Cleared Trades (k)

141,289

167,213

-15.5 %

169,513

-16.7 %

576,006

579,285

-0.6 %

Cboe Clear Europe Net Settlements (k)

1,285

1,099

16.9 %

1,431

-10.2 %

5,216

4,300

21.3 %

1 In the second quarter of 2025, Digital futures products were transitioned to Cboe Futures Exchange. Futures metrics prior to the second quarter of 2025 exclude Digital futures products.

April 2026 Trading Volume Highlights  

U.S. Options

Cboe’s proprietary index options set a single-day record on April 14 with 9.0 million contracts traded.S&P 500 Index (SPX) options set a single-day record on April 17 with 6.7 million contracts traded.Several areas across the business saw the second-highest monthly ADV on record, including Cboe’s proprietary index options (6.3 million), SPX options (5.0 million), mini-SPX options (XSP) (188 thousand contracts), and trading during Cboe’s Global Trading Hours (GTH) session (8:15 p.m. to 9:25 a.m. ET) (175 thousand contracts).

About Cboe Global Markets

Cboe Global Markets (Cboe: CBOE) is a leading global markets operator with a long history of innovation in equity derivatives. Since launching the world’s first listed options exchange in 1973, Cboe has pioneered landmark products, including the introduction of S&P 500® index options and the creation of the VIX® Index, the world’s leading gauge of market volatility, reshaping how investors manage risk and access opportunity. Today, Cboe operates derivatives, equities, and FX markets, providing trading, clearing, and investment solutions for customers worldwide. To learn more, visit www.cboe.com

Cboe Media Contacts

Cboe Analyst Contact

Angela Tu

Tim Cave

Kenneth Hill, CFA

+1-646-856-8734

+44 (0) 7593-506-719

+1-312-786-7559

atu@cboe.com

tcave@cboe.com

khill@cboe.com

CBOE-V

Cboe®, Cboe Global Markets®, Cboe Clear®, Cboe Futures Exchange®, CFE®, Cboe Volatility Index®, and VIX® are registered trademarks of Cboe Exchange, Inc. or its affiliates. Standard & Poor’s®, S&P®, SPX®, and S&P 500® are registered trademarks of Standard & Poor’s Financial Services, LLC, and have been licensed for use by Cboe Exchange, Inc. All other trademarks and service marks are the property of their respective owners.

Any products that have the S&P Index or Indexes as their underlying interest are not sponsored, endorsed, sold or promoted by Standard & Poor’s or Cboe and neither Standard & Poor’s nor Cboe make any representations or recommendations concerning the advisability of investing in products that have S&P indexes as their underlying interests. All other trademarks and service marks are the property of their respective owners.

Cboe Global Markets, Inc. and its affiliates do not recommend or make any representation as to possible benefits from any securities, futures or investments, or third-party products or services. Cboe Global Markets, Inc. is not affiliated with S&P. Investors should undertake their own due diligence regarding their securities, futures, and investment practices. This press release speaks only as of this date. Cboe Global Markets, Inc. disclaims any duty to update the information herein.

Nothing in this announcement should be considered a solicitation to buy or an offer to sell any securities or futures in any jurisdiction where the offer or solicitation would be unlawful under the laws of such jurisdiction. Nothing contained in this communication constitutes tax, legal or investment advice. Investors must consult their tax adviser or legal counsel for advice and information concerning their particular situation.

Cboe Global Markets, Inc. and its affiliates make no warranty, expressed or implied, including, without limitation, any warranties as of merchantability, fitness for a particular purpose, accuracy, completeness or timeliness, the results to be obtained by recipients of the products and services described herein, or as to the ability of the indices referenced in this press release to track the performance of their respective securities, generally, or the performance of the indices referenced in this press release or any subset of their respective securities, and shall not in any way be liable for any inaccuracies, errors. Cboe Global Markets, Inc. and its affiliates have not calculated, composed or determined the constituents or weightings of the securities that comprise the third-party indices referenced in this press release and shall not in any way be liable for any inaccuracies or errors in any of the indices referenced in this press release.

There are important risks associated with transacting in any of the Cboe Company products discussed here. Before engaging in any transactions in those products, it is important for market participants to carefully review the disclosures and disclaimers contained at: https://www.cboe.com/us_disclaimers/

Options involve risk and are not suitable for all market participants. Prior to buying or selling an option, a person should review the Characteristics and Risks of Standardized Options (ODD), which is required to be provided to all such persons. Copies of the ODD are available from your broker or from The Options Clearing Corporation, 125 S. Franklin Street, Suite 1200, Chicago, IL 60606.

View original content to download multimedia:https://www.prnewswire.com/news-releases/cboe-global-markets-reports-trading-volume-for-april-2026-302763165.html

SOURCE Cboe Global Markets, Inc.

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Danaher Announces Quarterly Dividend

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WASHINGTON, May 5, 2026 /PRNewswire/ — Danaher Corporation (NYSE: DHR) announced today that its Board of Directors has approved a regular quarterly cash dividend of $0.40 per share of its common stock, payable on July 31, 2026 to holders of record on June 26, 2026.

ABOUT DANAHER
Danaher is a leading global life sciences and diagnostics innovator, committed to accelerating the power of science and technology to improve human health. Through our connected ecosystem of industry-leading businesses, we work side by side with customers to solve many of their most complex scientific and clinical challenges—helping move innovations from discovery to delivery faster for patients who depend on them.

Powered by the Danaher Business System, our advanced science and technology and proven ability to innovate help enable faster, more accurate diagnoses and reduce the time, cost, and risk required to discover, develop, and deliver life-changing therapies. Through continuous improvement and operational excellence, our approximately 60,000 associates worldwide are focused on delivering lasting impact and improving quality of life around the world, while building a healthier, more sustainable tomorrow. Explore more at www.danaher.com.

View original content:https://www.prnewswire.com/news-releases/danaher-announces-quarterly-dividend-302763206.html

SOURCE Danaher Corporation

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