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Study Uncovers How Much of Biological Aging is Driven by Random Noise Versus Dynamic Biologic Change

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LEXINGTON, Ky., May 23, 2024 /PRNewswire/ — A new groundbreaking study, recently published in *Nature Aging*, by researchers from the University of Chinese Academy of Sciences, TruDiagnostic, and Harvard, has unveiled significant insights into the mechanisms of epigenetic clocks, which are widely used to predict biological age. The study’s findings suggest that a large portion of the predictive accuracy of chronological clocks can be attributed to stochastic, or random, DNA methylation (DNAm) changes rather than deterministic biological aging processes.

Epigenetic clocks, such as those developed by Horvath and Zhang, have gained prominence for their ability to estimate an individual’s biological age with remarkable accuracy, based solely on patterns of DNA methylation. However, the precise mechanisms by which these changes in DNAm occur has remained largely unexplored until now.

The research team, led by Dr. Andrew Teschendorff, utilized sophisticated simulation models and extensive DNAm data from over 25 independent cohorts totaling 22,770 samples. Their analysis revealed that between 66% to 90% of the accuracy of various epigenetic clocks could be explained by stochastic processes. This finding was particularly pronounced in Zhang’s clock, which showed that up to 90% of its predictive capability could be attributed to these random changes.

Dr. Andrew E. Teschendorff, a senior author of the study, noted, “Our results further indicate that biological age-acceleration is unlikely to be the result of an increased rate of stochastic change, but instead being driven by non-stochastic processes. However, one exception to this seems to be mitotic age-acceleration in precancerous lesions.”

Furthermore, the study distinguished between different types of epigenetic clocks, finding that those more predictive of chronological age, like Zhang’s clock, were largely influenced by stochastic DNAm changes. In contrast, clocks like PhenoAge, which are more reflective of biological age, showed a lower degree of stochastic influence. This suggests that first generation clocks, trained to predict chronological age, have less utility in predicting outcomes of aging than clocks trained on other phenotypes of aging or biomarkers.

These insights are vital for the future development and refinement of epigenetic clocks, potentially guiding medical professionals towards more accurate assessments of biological aging and associated health risks.

“One trend we have seen in recent years is that clocks trained to predict chronological age have lower predictive power than newer clocks trained on biological information. Additionally, chronological clocks can sometimes increase with known lifespan extension interventions. This is counter intuitive. This study might explain why. Clocks trained to predict chronological age are driven by random variation over time while clocks which are predictive of lifespan seem to be much more dynamic and responsive to the ways we live our life” added Dr. Varun Dwaraka, a co-author of the study. 

The full study is available in the latest issue of *Nature Aging* and provides a comprehensive view of the stochastic components influencing epigenetic aging. This research not only advances our understanding of genetic aging mechanisms but also enhances the potential for personalized medical strategies based on more accurate DNA methylation profiling.

For further information, access the full paper here.

About TruDiagnostic

Home to the largest, private DNA methylation database in the world, TruDiagnostic is a leading health data company and CLIA-certified laboratory that specializes in epigenetic testing and research. In partnership with notable biotech developers, researchers, and academic institutions, we are transforming the healthcare potential of epigenetic data into actionable applications. We aim to improve people’s lives by arming patients and physicians with novel biological insights; enabling them to make the right lifestyle and medical decisions through information found in the fluid epigenome. With the ability to analyze more than 1,000,000 locations on one’s DNA, our TruAge biological aging tests provide the most in-depth results, and multi-omic correlations to accelerated aging.

Additional Contacts

Hannah Went, Director of Operations

General Inquiries  

(937) 570-0471  

(833) 963-1700

hannah@trudiagnostic.com

support@trudiagnostic.com

www.trudiagnostic.com

www.trudiagnostic.com

**Contact:**
Dr. Andrew E. Teschendorff
Email: andrew@sinh.ac.cn
University of Chinese Academy of Sciences, Shanghai, China

Emilie Arroyo, Media Relations
(786) 247-4579
emilie@trudiagnostic.com  
www.trudiagnostic.com

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SOURCE TruDiagnostic

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VeriPark selected by Queensland Country Bank to support major technology transformation

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LONDON, Sept. 4, 2026 /PRNewswire/ — VeriPark, a global financial services technology provider, announced that Queensland Country Bank has selected its customer experience solutions as part of a major transformation program designed to deliver more connected, and member-focused banking experiences.

Queensland Country Bank will implement VeriPark’s VeriChannel digital banking platform, VeriTouch CRM platform and VeriLoan loan origination system. Together, the solutions will support digital banking, onboarding, lending and customer engagement across digital and assisted channels.

The broader transformation also includes Fiserv’s Finxact core banking platform and Vision Next card management solution. By bringing these technologies together, Queensland Country Bank is creating a future-ready environment spanning core banking, cards, lending, customer relationship management and digital channels.

The program will help the bank progressively modernize its platforms, reduce technology complexity and create more integrated experiences across member touchpoints, while preserving its community and member-owned focus.

“This is an important step in the next chapter of Queensland Country Bank,” said Shawn Anderson, Chief Transformation Officer of Queensland Country Bank. “Our Members expect banking to be simple, reliable and personal. By partnering with Fiserv and VeriPark, we are investing in the foundations that will help us deliver better experiences, support our people and continue serving Queensland communities well into the future.”

“We are proud to partner with Queensland Country Bank as it builds the foundations for its next generation of Member experiences,” said David Dervish, Chief Revenue Officer at VeriPark. “By connecting digital banking, lending and customer engagement, our platform will help the bank deliver more personalised and seamless journeys while giving its teams a more unified view of every Member. We look forward to turning this transformation vision into tangible value for Members and employees.”

QCB (www.queenslandcountry.bank)
Queensland Country Bank is a member-owned bank committed to helping Queenslanders live better lives through better financial wellbeing achieved through personal service, local understanding and community-focused banking. With roots across regional Queensland, the bank provides a range of banking products and services for Members across the state.

VeriPark (veripark.com) 
VeriPark is a global solutions provider enabling financial institutions to become digital leaders by placing Customer Experience at the core of digital transformation. From Omnichannel Delivery and Customer Engagement to Branch Automation and Loan Origination, VeriPark helps financial institutions accelerate digital transformation, increase productivity, and achieve tangible business outcomes.

 

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Intouch Insight to Unveil Annual Drive-Thru Study at QSR Evolution Conference

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Intouch Insight (INX: CA) to reveal the results of its annual Drive-Thru Study during the main stage session at the QSR Evolution Conference in AtlantaMain stage reveal to be delivered by VP Sales, Marketing & Product Strategy Sarah Beckett and Chief Revenue Officer Laura Livers on Thursday, September 10, 2026, ahead of the day’s keynoteBeckett and Livers will also moderate a panel of quick service restaurant operators on the technologies shaping the drive-thru of the future

OTTAWA, ON, Sept. 3, 2026 /CNW/ — Intouch Insight Ltd. (OTCQX: INXSF) (“Intouch” or the “Company”), a provider of customer experience measurement solutions, today announced that it will present the findings of its annual Drive-Thru Study on the main stage at the QSR Evolution Conference, taking place September 8-10, 2026, at the Hyatt Regency Atlanta. This marks the fourth consecutive year Intouch has partnered with QSR Magazine and Arrowfly, formerly WTWH Media, to bring the study’s results to the conference stage.

The main stage session, “Intouch Insight Drive-Thru Report Reveal,” is scheduled for Thursday, September 10, 2026, at 8:45 a.m. Eastern Time, immediately ahead of the day’s keynote. Sarah Beckett, VP Sales,Marketing & Product Strategy, and Laura Livers, Chief Revenue Officer, will give attendees an early, exclusive look at the fastest, most accurate, and best customer service drive-thrus in America.

Beckett and Livers will also moderate a panel session, “Unveiling the Drive-Thru of the Future,” which goes deeper into the technologies and innovations separating winning brands, and what it takes to run a modern drive-thru that delivers consistency and experience at scale. Panelists include Taylor Crookston-Grace, Director, Brand Standard, BK US&C Operations; Michael MacLennan, Cofounder and Co-CEO, Tryarc; Chris Cheek, Chief Development Officer, Newk’s Eatery; Trace Miller, Founder & CEO, Konala; and Tim Sharpe, COO, Oliver’s Real Food.

Now in its fourth year, the QSR Evolution Conference brings together senior leaders from across the quick service restaurant industry for practitioner-led sessions on operations, technology, and customer experience. Intouch’s participation on the main stage reflects its continued work in customer experience measurement and operational audits for restaurant operators and other multi-location brands.

Cameron Watt, President and Chief Executive Officer of Intouch Insight, said:

“The drive-thru study has become one of the most anticipated benchmarks in the industry, and the main stage at QSR Evolution is the right place to reveal it. Our research shows where brands are winning on speed, accuracy, and service, and where the gaps still are. We are looking forward to putting that data in front of the operators who can act on it, and to a fourth year of partnering with QSR Magazine and Arrowfly to make it happen.”

About Intouch Insight

Intouch Insight offers a complete portfolio of customer experience management (CEM) products and services that help global brands delight their customers, strengthen brand reputation and improve financial performance. Intouch helps clients collect and centralize data from multiple customer touch points, gives them actionable, real-time insights, and provides them with the tools to continuously improve customer experience. Founded in 1992, Intouch is trusted by over 300 of North America’s most-loved brands for their customer experience management, customer survey, mystery shopping, mobile forms, operational and compliance audits, geolocation data capture and event marketing automation solutions. For more information, visit intouchinsight.com.

Certain statements included in this news release including those related to the Company’s quarterly results, future products, opportunities and cost initiatives, strategies, and other statements that are predictive in nature that depend upon or refer to future events or conditions, or that include words such as “expects”, “anticipates”, “intends”, “plans”, “believes”, “estimates”, or similar expressions, are forward-looking statements within the meaning of applicable Canadian securities laws. Forward-looking statements that are made as of the date hereof, which by their nature are necessarily subject to risks and uncertainties and other factors that may cause actual results, performance or achievements of the Company to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. Such statements reflect the Company’s current views with respect to future events, and are based on information currently available to the Company and on hypotheses which it considers to be reasonable; however, management cautions the reader that hypotheses relative to future events which are beyond the control of management could prove to be false, given that they are subject to certain risks and uncertainties. Please refer to the risks set forth in the Company’s most recent annual MD&A and the Company’s continuous disclosure documents that can be found on SEDAR+ at www.sedarplus.ca. The Company does not intend, and disclaims any obligation, except as required by law, to update or revise any forward-looking statements whether as a result of new information, future events or otherwise.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

SOURCE Intouch Insight Ltd.

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Lyntris Completes CDR for KSAT Hyperion Satellite Program

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Tri-band RF system advances for KSAT’s next-generation HYPER relay network

WASHINGTON, Sept. 3, 2026 /PRNewswire/ — Lyntris Inc. (NYSE: LYNX), a defense technology company delivering sense-to-act connectivity solutions for the modern connected battlespace has completed Critical Design Review (CDR) for the tri-band antenna system in development for Kongsberg Satellite Services (KSAT)’s two-satellite Hyperion mission, marking a key milestone as the program advances toward hardware integration, qualification, and flight.

Hyperion is the pathfinder for HYPER, KSAT’s next-generation hybrid RF and optical relay network designed to extend global connectivity into orbit. The architecture will enable spacecraft to move mission data through relay satellites when direct ground-station access is unavailable, reducing latency and increasing access to time-sensitive information.

Delivering tri-band performance in a single antenna system is a demanding engineering problem. Each frequency band has to be tightly controlled — filtering out unwanted signals, isolating the bands from each other, and minimizing signal loss. But optimizing for one band can easily degrade performance in another. Meeting those requirements for all three simultaneously, inside a compact, space-qualified envelope, leaves little room for error.

That difficulty compounds when the design moves from RF engineering into flight hardware, and the completed system then has to be validated in test facilities capable of characterizing performance across all three bands at once, a capability few organizations maintain in-house.

Completion of CDR as planned demonstrates the technical maturity of the design and reflects the close engineering partnership between Lyntris and KSAT as both teams move toward flight hardware.

Lyntris brings RF engineering, manufacturing, system integration, and multi-band testing together under one roof. That combination — along with proprietary design and process IP — is what allows a design as demanding as the tri-band antenna to move from requirements to flight hardware.

“Hyperion is an important step toward a more connected and resilient space architecture,” said Madison Dye, Lyntris’ Vice President of C5ISR. “We’re proud to partner with KSAT and provide the advanced RF technology needed to make that architecture work. Completing CDR on schedule demonstrates our ability to move complex antenna systems from requirements to flight-ready hardware with speed and discipline.”

About Lyntris

Lyntris is a defense technology company delivering sense-to-act connectivity solutions for the modern, connected battlespace. Combining differentiated hardware, software and mission expertise, Lyntris helps customers detect threats earlier, decide faster and act with precision in contested, multi-domain environments.

Forward-Looking Statements

This press release contains “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. These forward-looking statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements generally can be identified by the use of forward-looking terminology such as “expect,” “believe,” “anticipate,” “may,” “could,” “intend,” “plan,” “estimate,” “target,” “predict,” “project,” “will,” “should,” “forecast,” “outlook” or similar expressions, or by discussion of strategies, plans or intentions.

Forward-looking statements in this press release include, but are not limited to, statements regarding: the expected timeline and progress of the Hyperion antenna program; the anticipated technical performance and capabilities of the tri-band antenna system; expected production and delivery schedules; the role of the antenna in KSAT’s HYPER relay network architecture; Lyntris’ ability to move complex antenna systems from requirements to flight-ready hardware; statements regarding Lyntris’ manufacturing, integration and qualification capabilities; and the potential for expanded business opportunities.

These statements are based on current expectations, estimates, assumptions and projections of Lyntris’ management and are neither predictions nor guarantees of future events, circumstances or performance. Forward-looking statements are inherently subject to known and unknown risks, uncertainties and assumptions that could cause actual results to differ materially from those expressed or implied by such statements. Important factors that could cause actual results to differ materially from those discussed in the forward-looking statements include, without limitation: dependence on KSAT’s program decisions, priorities, funding and continued support for the Hyperion demonstration mission and HYPER relay network; technical risks inherent in developing, qualifying, integrating and operating space-qualified hardware; the risk that completion of CDR does not guarantee successful qualification, integration or flight; the competitive environment for RF and antenna technologies; supply chain disruptions, shortages or constraints affecting specialized materials and components; schedule delays, technical challenges or cost overruns in complex space and defense programs; uncertainties in U.S. government and commercial space budgets, appropriations and customer spending; changes in applicable laws, regulations or government procurement policies; and other factors described under “Risk Factors” and elsewhere in Lyntris’ filings with the Securities and Exchange Commission, including its registration statement on Form S-1, as amended, copies of which are available free of charge on the SEC’s website at www.sec.gov under Lyntris Inc.

The forward-looking statements included in this press release are only made as of the date of this press release. Factors or events that could cause our actual results to differ may emerge from time to time, and it is not possible for us to predict all of them. We may not actually achieve the plans, intentions or expectations disclosed in our forward-looking statements, and you should not place undue reliance on our forward-looking statements. We undertake no obligation to publicly update or review any forward-looking statement, whether as a result of new information, future developments or otherwise, except as may be required by applicable law.

Nothing in this press release, including use or display of third parties’ trademarks, service marks, trade name or products, should be construed as an approval, endorsement, guarantee or sponsorship by any third parties of Lyntris Inc., its products, business or financial performance or any aspect of this press release.

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SOURCE Lyntris

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