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Ig Nobel Prize Awarded to Takanori Takebe for “Butt-Breathing” Study

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Go ahead, crack a joke. Butt seriously, this research from an expert at Cincinnati Children’s and the Tokyo Medical and Dental University might save lives someday by helping people when they cannot get enough oxygen via their lungs

CINCINNATI, Sept. 12, 2024 /PRNewswire/ — On one hand, Takanori Takebe, MD, PhD, would prefer to be remembered for his multiple breakthrough contributions to organoid medicine. However, he may never be forgotten for his work to demonstrate that people can “breathe” through their butts.

Takebe’s unusual insight about an alternative way to deliver oxygen to the bloodstream inspired headlines when a successful animal-model study was featured in June 2021 on the cover of the journal Med. His team’s findings have since attracted attention from media outlets including the New York Times, New York Post, Science NOW, and the Canada-based science television show  “The Nature of Things.”

Now, Takebe has received the ultimate snarky scientific honor: an Ig Nobel Prize.

This satiric prize has been awarded to 10 researchers each year since 1991 by the scientific humor magazine Annals of Improbable Research to “honor achievements that first make people laugh, and then make them think.” This year’s prizes were presented Sept. 12, 2024, at the Massachusetts Institute of Technology by actual Nobel Prize laureates.

Takebe is a native of Japan who holds academic posts in Tokyo and the United States. At Cincinnati Children’s, Takebe is Director for Commercial Innovation at the Center for Stem Cell and Organoid Research and Medicine (CuSTOM). In Japan, he is a professor with the Tokyo Medical and Dental University’s Institute of Research.

On the side, he began thinking several years ago about an odd, eel-like fish called a loach. Sometimes this freshwater bottom-dweller can wind up in water that’s running low on oxygen. When this occurs, the fish augments water-breathing via its gills by gulping surface air directly to its intestines.

What if people could do something similar?  Well, it appears quite possible.

“There are multiple health conditions including respiratory distress in newborn patients that can threaten lives by disrupting our lungs’ ability to transfer oxygen to the bloodstream. These include injuries or inflammation affecting the airway, pneumonia filling the lungs with fluid, and so on. During the COVID pandemic, many patients suffered in part because there was a global shortage of ventilators and limited accessibility to ECMO,” says Takebe. “Enteric ventilation could serve as an important alternative oxygen delivery route. Further confirmation is needed by our initial studies indicate that our ventilation system is capable of supporting patients experiencing severe respiratory failure.”

The butt-breathing concept involves delivering a liquid (called a perfluorocarbon) that can be loaded with much more oxygen than water normally carries.  When delivered through a rectal tube, the lower intestine can absorb oxygen from the liquid and send it directly into the bloodstream—much like receiving an enema.  

Takebe and colleagues have shown that this method has helped rodents and porcine models survive low-oxygen conditions that would otherwise be fatal.  

Since the initial studies, Takebe and colleagues have co-founded a start-up company called EVA Therapeutics, Inc., to further pursue human clinical trials in Japan. In June 2024, the company announced providing its first dose to a healthy human participant.

More research is needed to evaluate and fine-tune the delivery system, particularly for sick people in multiple settings. Goals include learning how much oxygen can be reliably delivered, for how long, and whether receiving the liquid poses any unforeseen risks.

The good news: Takebe’s Ig Nobel honor comes with a monetary prize to carry on the work–a single banknote worth 100 trillion Zimbabwean dollars. Ig Nobel officials say that adds up to about 40 cents in U.S. currency.

Learn more about Takebe’s work

Learn How Enteral Ventilation Concept Got Started

Read More About Organoid Research at Cincinnati Children’s

Watch an Employee Video About Dr. Takebe

Media Contact:
Tim Bonfield 
Cincinnati Children’s
Timothy.bonfield@cchmc.org 

 

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SOURCE Cincinnati Children’s Hospital Medical Center

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Asian Hall of Fame Heritage Gala Highlights Impactful Legacy

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Benefit supported Women In Tech, Entertainment, Science & Sports Scholars

LOS ANGELES, May 13, 2026 /PRNewswire/ — Global ambassador Asian Hall of Fame highlighted positive messages of interracial synergy with its Heritage Gala on May 1, 2026 at the iconic Biltmore Los Angeles. CBS LA Anchor Suzie Suh served as Master of Ceremonies of the festive Asian Heritage Month celebration brought to life by vibrant heritage costumes representing Asia, Latin America, and the U.S. Virgin Islands. The intergenerational benefit funded Women In Tech, Entertainment, Science & Sports (WinTESS) scholarships for 103 applicants from all racial backgrounds.

Guests from California, Washington, Oregon, Hawaii, and New York applauded the Class of 2026 Official Announcement, including Asian Hall of Fame’s first-ever Major League Baseball Inductee Hideo Nomo, nominated by the Los Angeles Dodgers, and DTLA muralist Robert Vargas as Goodwill Ambassador.

Dedicated San Marino philanthropist and Board of Governors Chairwoman Melinda Rogers was honored as the 2026 Woman of the Year, with a moving speech presented by her younger brother William Rogers. Chairwoman Rogers highlighted the endearing impact of family, and delighted audiences with her custom Korean hanbok, designed alongside Anna Kim at her Koreatown boutique.

Distinguished philanthropist Loida Nicolas Lewis (Inductee 2007) shared an inspiring fireside chat with stories of family legacy and community empowerment. Guests received commemorative autographed memoirs, and complimentary gifts from Nan Yang Delight and SUP. Inductees in attendance were Marc Anthony Nicolas, Kristen Lui, incoming Inductees Kitty Lo and Maggie Tseng, Official Design Partner of the 2026 Season.

The dramatic Heritage Costume Show, sponsored by Meridien Vacation Homes, presented pageant holders including a Rose Pageant Princess, Miss Asia USA, Miss Teen Latina Global, Hi-Teen USA, Miss International U.S. Virgin Islands, Miss Taiwanese American, and Mrs. Asia Glamour.

Maki Mae performed from her upcoming album release with pianist Jason Lo and cellist Ryan Phipps. Walter Nishinaka and Los Angeles Taiko Collective kicked off raffle drawings, including an 18-carat gold ring donated by long-standing supporter Vartan Kazanjian, owner of Estate Jewelers of South Pasadena.

ABOUT ASIAN HALL OF FAME
Established in 2004, Asian Hall of Fame strengthens interracial synergy by advancing mainstream recognition of Asian and Native legacy. Inductees include Connie Chung, Kristi Yamaguchi, Margaret Cho, amongst others. Contact: press@asianhalloffame.org, (626) 600-9418, www.asianhalloffame.org.

View original content to download multimedia:https://www.prnewswire.com/news-releases/asian-hall-of-fame-heritage-gala-highlights-impactful-legacy-302771594.html

SOURCE Asian Hall of Fame

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Notice of Data Privacy Incident

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MOUNT STERLING, Ill., May 13, 2026 /PRNewswire/ — Brown County

Brown County, Illinois provides notice of a data privacy incident involving personal information of certain county constituents and staff.

What Happened? On April 3, 2025, we received alerts of unusual activity in one of our email accounts. We launched an immediate investigation, and retained independent cyber incident response specialists to assist. The investigation determined that two email accounts experienced unauthorized access. We have no evidence of fraud or identity theft from this incident.

What Information Was Involved. The information involved varied by individual, and may have included a first and last name along with a Social Security number, driver’s license number, government issued identification number, medical information, or health insurance information.

What We Are Doing. In addition to the above, we are offering complimentary credit monitoring and identity protection services to individuals whose Social Security numbers were believed to be involved.

What You Can Do. Generally, it is best practice to remain vigilant for incidents of identity theft and fraud from any source by reviewing your account statements and credit reports for suspicious activity and errors. If you discover any suspicious or unusual activity, promptly contact your financial institution or service provider.

Individuals are entitled to one free credit report annually from each of the three major credit reporting bureaus, TransUnion, Experian, and Equifax. To order a free credit report, visit www.annualcreditreport.com or call 1-877-322-8228.

Individuals may further learn about identity theft, fraud alerts, credit freezes, and the steps to take to protect personal information by contacting the credit reporting bureaus, the Federal Trade Commission (FTC), or state Attorneys General. The FTC encourages those who discover that their information has been misused to file a complaint with them. It may be reached at 600 Pennsylvania Ave. NW, Washington, D.C. 20580; www.identitytheft.gov; 1-877-ID-THEFT (1-877-438-4338); and TTY: 1-866-653-4261.

For More Information, you may contact us at 1-800-405-6108, Monday through Friday, 8:00 a.m. to 8:00 p.m. EST for further assistance.

View original content:https://www.prnewswire.com/news-releases/notice-of-data-privacy-incident-302771596.html

SOURCE Kennedys CMK LLP

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SharkNinja Set to Join S&P MidCap 400; Flowers Foods and F&G Annuities & Life to Join S&P SmallCap 600

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NEW YORK, May 13, 2026 /PRNewswire/ — S&P Dow Jones Indices will make the following changes to the S&P MidCap 400, S&P SmallCap 600: 

SharkNinja (NYSE: SN) will replace Flowers Foods Inc. (NYSE: FLO) in the S&P MidCap 400, and Flowers Foods will replace CSG Systems Intl Inc. (NASD: CSGS) in the S&P SmallCap 600 effective prior to the opening of trading on Monday, May 18. NEC Corporation (TSE: 6701) is acquiring CSG Systems Intl in a deal expected to close soon, pending final closing conditions.F&G Annuities & Life Inc. (NYSE: FG) will replace Mister Car Wash Inc. (NASD: MCW) in the S&P SmallCap 600 effective prior to the opening of trading on Tuesday, May 19. Leonard Green & Partners L.P. is acquiring Mister Car Wash in a deal expected to close soon, pending final closing conditions.

Following is a summary of the changes that will take place prior to the open of trading on the effective date:

Effective Date

Index Name

Action

Company Name

Ticker

GICS Sector

May 18, 2026

S&P MidCap 400

Addition

SharkNinja

SN

Consumer Discretionary

May 18, 2026

S&P MidCap 400

Deletion

Flowers Foods

FLO

Consumer Staples

May 18, 2026

S&P SmallCap 600

Addition

Flowers Foods

FLO

Consumer Staples

May 18, 2026

S&P SmallCap 600

Deletion

CSG Systems Intl

CSGS

Industrials

May 19, 2026

S&P SmallCap 600

Addition

F&G Annuities & Life

FG

Financials

May 19, 2026

S&P SmallCap 600

Deletion

Mister Car Wash

MCW

Consumer Discretionary

ABOUT S&P DOW JONES INDICES

S&P Dow Jones Indices is the largest global resource for essential index-based concepts, data and research, and home to iconic financial market indicators, such as the S&P 500® and the Dow Jones Industrial Average®. More assets are invested in products based on our indices than products based on indices from any other provider in the world. Since Charles Dow invented the first index in 1884, S&P DJI has been innovating and developing indices across the spectrum of asset classes helping to define the way investors measure and trade the markets.

S&P Dow Jones Indices is a division of S&P Global (NYSE: SPGI), which provides essential intelligence for individuals, companies, and governments to make decisions with confidence. For more information, visit www.spglobal.com/spdji/en/

FOR MORE INFORMATION:

S&P Dow Jones Indices
index_services@spglobal.com

Media Inquiries
spdji.comms@spglobal.com

View original content:https://www.prnewswire.com/news-releases/sharkninja-set-to-join-sp-midcap-400-flowers-foods-and-fg-annuities–life-to-join-sp-smallcap-600-302771602.html

SOURCE S&P Dow Jones Indices

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