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Target ALS and Modality.AI Collaborate in Multimodal Study of ALS

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Direct-to-participant study to reach 150 people living with ALS, with 2 participants already enrolled.

NEW YORK, Sept. 26, 2024 /PRNewswire/ — In a first-of-a-kind collaboration, Target ALS, a foundation breaking down barriers to amyotrophic lateral sclerosis (ALS) research to find effective treatments, and Modality.AI, whose platform measures what patients say and do in conversation with the virtual guide Tina, in-clinic and remotely, are conducting a study to evaluate the potential of this unique audiovisual platform to detect even the smallest changes in disease symptoms over time in ALS patients. A subset of 5 international sites, part of the Target ALS Global Natural History Study, is now recruiting 150 ALS and 50 healthy control participants and will deploy Modality.AI’s innovative digital health platform, including at locations in Spanish-speaking countries, over the next 3 years.

Participants will engage in twice-monthly Modality sessions over a period of 16-18 months, utilizing the platform’s self-directed assessment accessible on personal devices. Tina, a virtual guide, provides consistent engagement while capturing speech and facial biomarkers.

Results from this pioneering study will be made available to the research community on the Target ALS Data Engine.

Study Details
Participants will be consented in the clinic and then asked to complete twice-monthly Modality sessions at home. Sessions include a reading passage, spontaneous speech, activities of daily living such as brushing their hair and washing their face, and various cognitive tasks such as word recall and sequential movements. Modality works through a web browser, so no app installation or account creation is required. 

Modality’s Platform Offers Unique Advantages

The assessment is self-directed and takes place on a participant’s own device (computer, tablet, or phone), making it accessible in the convenience of their home. For trial sponsors, this minimizes the need for in-clinic assessment and the time and cost of shipping devices.The introduction of Tina, a virtual guide, encourages engagement through a welcoming interface for capturing the patient’s speech and facial biomarkers in a comfortable setting in just a few minutes. Tina provides consistent guidance, eliminating variance between clinicians, a confounding variable in studies.Modality’s cloud-based platform utilizes AI and multimodal signal processing to extract speech and facial measures from participants’ video in real time for immediate verification and analysis.The Patient Report of Problems™ (PROP™) allows trial participants to describe specific problems and symptoms in their own words. This study marks the first use of the PROP in a multilingual multicenter ALS Study.

Improving Study Participation, Retention, and Participant Diversity 
Advances in digital health technologies (DHTs) allow patients to participate in clinical research studies in the privacy and comfort of their own homes, rather than traveling to an investigator’s site.

Most DHT-based studies rely on continuous monitoring of patients or require patients to record activities in an electronic diary regularly. Modality’s approach is a brief speech and movement assessment led by a virtual guide, assuring privacy for participants and those around them.  Target ALS and Modality adhere to recognized privacy standards with data being used for research purposes only.

A well-known trial challenge is that access to trial sites is a significant burden for many. Giving patients the option to participate from home increases the likelihood of joining a study, reduces drop-out rates, and increases adherence to the study protocol. By reaching a wider range of patients, underrepresented groups are more readily included, which helps ensure that treatments can be effective over the widest possible population.

“We are delighted to participate in what is the first clinical study of Modality’s self-directed remote monitoring of speech and motor function with Target ALS,” said Modality.AI CEO, David Suendermann-Oeft. “Speech, language, video, and other multimodal analysis technologies may revolutionize remote neurological assessments. We look forward to this collaboration and our work together leading to more efficient clinical trials and, in turn, faster and more efficient drug discovery.”

“Modality.AI’s technology is at the forefront of digital health technologies being evaluated for the utility of predicting and tracking disease progression in ALS patients,” said Amy Easton, Senior Director of Scientific Programs at Target ALS. “These technologies are being developed to allow clinicians, patients, and caregivers to measure disease symptoms in a more sensitive and reliable manner than standard clinical assessments, and in the future, may even replace clinical outcome assessments used to evaluate novel treatments for ALS.”

To learn more about participating in this study click here.

About Target ALS

Founded in 2013, Target ALS is a 501(c)(3) medical research foundation breaking down barriers to Amyotrophic Lateral Sclerosis (ALS) research to find effective treatments. The organization has revolutionized ALS research through their landmark Innovation Ecosystem model, fostering unprecedented collaborations between academia and the pharma and biotech industry, providing no-strings-attached access to critical research tools, and acting as a hub of communication and networking for the worldwide scientific community. Driven by impatient optimism, deliberate disruption, and radical collaboration, Target ALS aims to transform ALS into a manageable disease, realizing a world where Everyone Lives. For more information, visit www.targetals.org

About Modality.AI
Modality.AI has developed the first conversational AI platform to accurately and objectively measure, analyze and track participant data through facial, speech, and movement patterns. The Modality platform utilizes a virtual guide, Tina, to remotely administer clinical trial assessments. The company is led by a team of world-class scientists, clinicians, technologists, and serial entrepreneurs.  Modality’s platform has shown validation through numerous peer-reviewed publications (https://modality.ai/publications), and is being used by leading research institutions, biotech firms, and top-10 pharmaceutical companies in observational studies and clinical trials. For additional information, please visit modality.ai

Contact
Stephanie Ishoo
stephanie.ishoo@targetals.org

David Fox
david.fox@modality.ai

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Hisense Celebrates Earth Day: The Quiet Green Shift Happening Inside Households Through Smarter Appliances

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DUBAI, UAE, April 22, 2026 /PRNewswire/ — There’s something futuristic about a refrigerator that thinks for itself. Not in a science-fiction, take-over-the-world kind of way, but in the everyday miracle of a 620-litre side-by-side unit deciding, on its own, that 3am is the perfect time to run its compressor at minimal power because nobody’s opening the door anyway.

This is the green revolution that nobody talks about at climate summits. While world leaders debate carbon credits and industrial emissions, a quieter transformation is unfolding in kitchens, utility rooms, and living spaces across the UAE and beyond. It happens every time a washing machine calculates the precise amount of water needed for that half-load of towels, or when an air conditioner’s inverter technology throttles down instead of cycling on and off like an energy-guzzling metronome.

Earth Day, falling on 22 April this year, typically conjures images of tree-planting ceremonies and beach clean-ups. Worthy endeavours, certainly. But the environmental impact of what sits in your home, running twenty-four hours a day, seven days a week, fifty-two weeks a year, rarely gets the attention it deserves.

On average, washing machines use 19 gallons of water per load, and the average household runs between 5 and 6 loads per week. Based on those figures, most washers use up to 5,605 gallons of water annually . Swap that for a modern front-load unit with AI wash programs, like Hisense’s models, and that figure can drop by up to 50 percent. Multiply this across the roughly 500,000 households in Dubai alone, and we’re suddenly talking about water savings that would make a desalination plant executive weep with joy.

The same logic applies to electricity consumption, a particularly pressing concern in a region where summer temperatures regularly exceed 45°C and air conditioning is a necessity. The difference between a conventional split AC unit and one equipped with inverter technology isn’t marginal, it’s substantial enough to show up on utility bills within the first month of operation.

Intelligence as an Environmental Strategy

What makes the current generation of home appliances genuinely different isn’t just improved efficiency ratings or eco-labelling. It’s the integration of AI into the very fabric of how these machines operate.

Hisense, a brand that has positioned itself at this intersection of technology and sustainability, describes its approach as a “dual-track strategy of intelligence plus green development.” Its ConnectLife ecosystem, available on select refrigerators, washing machines, dishwashers, and air conditioners, monitors energy consumption in real-time, learns household patterns, and makes AI-driven recommendations that, over time, compound into meaningful resource savings.

A Hisense 14-place setting dishwasher with auto-wash technology, for instance, doesn’t simply run the same cycle regardless of load. It assesses soil levels and adjusts water temperature and duration accordingly. A half-load mode means running appliances at appropriate capacity rather than wasting resources on unnecessary full cycles.

Multi-airflow cooling systems that reduce temperature fluctuation and preserve food longer. No-frost technology that eliminates the energy waste of ice buildup. Inverter compressors that modulate power consumption rather than running at full throttle constantly. These technologies have existed in various forms for years. What’s changed is their integration into accessible price points and mainstream product lines, making efficient living achievable for households beyond the ultra-premium market.

The Gulf region presents a fascinating case study for domestic sustainability. Per capita energy consumption ranks among the highest globally, driven by climate control requirements, water desalination dependencies, and historically subsidised utility costs. Yet the UAE has simultaneously positioned itself as a regional leader in renewable energy investment and sustainability commitments.

This creates a unique environment where smart appliance adoption carries amplified significance. A 1.5-ton inverter split AC running across a typical Abu Dhabi summer doesn’t just save its owner money, it reduces the load on an electrical grid increasingly powered by solar and nuclear generation. The connection between individual choices and collective outcomes becomes tangible in ways that might seem abstract in milder climates.

The rise of connected appliances adds another dimension. Remote diagnostics can extend product lifespans by identifying minor issues before they become terminal failures. Software updates can improve efficiency algorithms years after purchase. Energy monitoring creates accountability loops that encourage conscious consumption patterns.

Steam wash functions on modern washing machines reduce the need for hot-water cycles while improving allergen removal. Anti-bacterial filters in air conditioning units address both health and environmental concerns simultaneously. These convergences suggest that the old tension between convenience and conscience may be resolving itself through engineering rather than requiring consumers to choose sides.

The Household as Climate Actor

There’s something democratic about domestic sustainability. Industrial emissions reductions require policy negotiations, capital investments, and coordination across complex stakeholder ecosystems. Choosing a more efficient refrigerator requires a trip to the appliance store and perhaps a slightly higher upfront cost that will recoup itself over the product’s operational lifetime.

This isn’t to diminish the necessity of systemic change, individual action cannot substitute for structural transformation. But the two approaches complement rather than compete. Households equipped with intelligent appliances consume fewer resources, place less strain on infrastructure, and model consumption patterns that cascade through communities.

The quiet green shift happening inside households won’t make headlines the way renewable energy megaprojects or electric vehicle adoption rates do. But every time that dishwasher calculates optimal water usage, every time that inverter compressor modulates instead of cycles, every time that smart refrigerator adjusts its cooling schedule based on door-opening patterns, something meaningful happens. Millions of these moments, aggregated across millions of households, compound into impact that rivals any single infrastructure project.

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Dreame Nebula NEXT Auto expands academic collaboration to accelerate AI-driven automotive innovation

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UC Berkeley engagement underscores long-term investment in autonomous systems, engineering depth and intelligent vehicle development

BERKELEY, Calif., April 22, 2026 /PRNewswire/ — Dreame Nebula NEXT Auto has deepened its engagement with leading academic institutions, including the University of California, Berkeley, as it accelerates development of AI-defined vehicles and next-generation autonomous systems. The collaboration signals a long-term commitment to advancing core technologies that will shape the future of intelligent automotive motion.

The engagement brought Nebula NEXT engineers and leadership together with Berkeley researchers specialising in autonomous control systems, AI and intelligent transportation. The sessions focused on translating advanced research into real-world vehicle systems, with particular emphasis on safety, control and full-stack AI integration.

Jake Ma, Executive of Dreame Nebula NEXT Auto, said: “We aren’t building a car. We are building a new brain for the physical world. To us, the car is the only physical mothership capable of carrying the extreme compute required by large AI models today.”

The visit forms part of a broader strategy to anchor Nebula NEXT’s development in deep technical collaboration. By working closely with academic experts, the company is strengthening its approach to autonomous driving, vehicle intelligence and system-level engineering.

Nebula NEXT builds on Dreame Technology’s foundation in precision engineering and AI-driven innovation. This heritage underpins a shift from software-defined vehicles to AI-defined vehicles, where intelligence is embedded across the entire system, from perception and decision-making to chassis and powertrain control.

The company’s technical direction centres on integrating AI into the core dynamics of how vehicles operate. This includes continuous learning systems, multi-agent architectures and high-performance computing platforms designed to support real-time decision-making in complex driving environments.

Nebula NEXT first drew global attention at CES 2026 with the debut of the Nebula NEXT 01, a four-door electric hyper-sedan concept. The vehicle delivers 1.8-second acceleration from 0 to 100 km/h, more than 2,000 horsepower and a lightweight structure built from proprietary Blue Carbon Fiber.

Momentum continued with a high-profile appearance during the Super Bowl LVIII broadcast, extending the brand’s reach across North America and reinforcing its position as an emerging force in automotive technology.

Alongside performance, the company continues to prioritise foundational innovation. Its architecture combines AI-native operating systems, zonal electrical design and high-density computing platforms to enable scalable, intelligent vehicle systems.

Nebula NEXT is now entering a phase focused on system execution, engineering depth and scalable technology development. The company will present further advances at an upcoming Silicon Valley event on 27 April 2026, where it will unveil new products and core technologies.

By combining global market momentum, academic collaboration and a focus on engineering fundamentals, Dreame Nebula NEXT is positioning itself at the centre of the transition to AI-defined mobility.

Media contact:
Li Tong, Dreame Nebula Next Auto PR head, litong2@dreame.tech
Website: https://www.dreametech.com

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Sucden Financial Enables Client Trading in Shanghai Nickel Futures

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LONDON, April 22, 2026 /PRNewswire/ — Sucden Financial, the multi-asset execution, clearing and liquidity provider, announces that clients can now trade nickel futures and options on the Shanghai Futures Exchange (SHFE), following today’s opening of the contract to international participants.

Sucden Financial offers access to SHFE through its Overseas Intermediary status and established Chinese banking relationships. Clients can manage exposure across SHFE, the London Metal Exchange (LME) and more than 20 other global commodities markets through a single account.

In addition to SHFE nickel contracts, Sucden Financial’s clients can access the following Chinese exchanges: the Shanghai International Energy Exchange, the Dalian Commodity Exchange and the Zhengzhou Commodity Exchange.

Lucy Wainman, Head of Sales (China) at Sucden Financial, said:

“We are pleased to offer clients the opportunity to trade Shanghai nickel futures and options contracts, further broadening our access to Chinese markets. This milestone reflects the hard work of our team and the long-standing relationships we have built in China. We would like to thank SHFE and Chinese regulators for their support and constructive engagement.”

Marc Bailey, CEO of Sucden Financial, said:

“Expanding our global exchange coverage to include access to onshore mainland Chinese markets supports our organic growth strategy. By adding access to SHFE, we provide clients with an extended global reach through a single account. Continued investment in technology underpins our long-term commitment to our clients, enabling them to respond quickly to changing market dynamics and capture emerging opportunities.”

About Sucden Financial

With a history and heritage in commodity futures and options trading, Sucden Financial has evolved and diversified to become a leading global multi-asset execution, clearing and liquidity provider across FX, fixed income, and commodities.

Sucden Financial has a proven track record of over 50 years in financial markets. Since its foundation in 1973, it has been supported by its parent, Sucden, one of the world’s leading soft commodity trading groups, while remaining fully independent in its day-to-day trading operations.

Sucden Financial Limited is authorised and regulated by the Financial Conduct Authority.

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